Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer’s disease
暂无分享,去创建一个
[1] B. Hallgren,et al. THE EFFECT OF AGE ON THE NON‐HAEMIN IRON IN THE HUMAN BRAIN , 1958, Journal of neurochemistry.
[2] R. Terry,et al. ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA. , 1964, The American journal of pathology.
[3] N. Geschwind. Disconnexion syndromes in animals and man. I. , 1965, Brain : a journal of neurology.
[4] J. O'brien,et al. Lipid composition of the normal human brain: gray matter, white matter, and myelin. , 1965, Journal of lipid research.
[5] P. Yakovlev,et al. The myelogenetic cycles of regional maturation of the brain , 1967 .
[6] A. Minkowski,et al. Regional Development of the Brain in Early Life , 1968 .
[7] T A Sears,et al. The effects of experimental demyelination on conduction in the central nervous system. , 1970, Brain : a journal of neurology.
[8] A Barbeau,et al. [Huntington's chorea: 1872-1972]. , 1972, L'union medicale du Canada.
[9] G. Rouser,et al. Lipids in the nervous system of different species as a function of age: brain, spinal cord, peripheral nerve, purified whole cell preparations, and subcellular particulates: regulatory mechanisms and membrane structure. , 1972, Advances in lipid research.
[10] S G Waxman,et al. Conduction in myelinated, unmyelinated, and demyelinated fibers. , 1977, Archives of neurology.
[11] B Chance,et al. Hydroperoxide metabolism in mammalian organs. , 1979, Physiological reviews.
[12] J A Corsellis,et al. VARIATION WITH AGE IN THE VOLUMES OF GREY AND WHITE MATTER IN THE CEREBRAL HEMISPHERES OF MAN: MEASUREMENTS WITH AN IMAGE ANALYSER , 1980, Neuropathology and applied neurobiology.
[13] R. Thompson,et al. The Molecular basis of neuropathology , 1981 .
[14] A. Meyer,et al. Paul Flechsig’s System of Myelogenetic Cortical Localization In the Light of Recent Research in Neuroanatomy and Neurophysiology Part II , 1981, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.
[15] R. Wiggins. Myelin development and nutritional insufficiency , 1982, Brain Research Reviews.
[16] M. Moscarello,et al. Changes in lipid phase behaviour in human myelin during maturation and aging , 1983, FEBS letters.
[17] Richard P. Bunge,et al. The Biology of the Oligodendrocyte , 1984 .
[18] P. Morell,et al. In Vivo Metabolism of Oligodendroglial Lipids , 1984 .
[19] J. Thompson,et al. X-ray diffraction evidence for myelin disorder in brain from humans with Alzheimer's disease. , 1984, Biochimica et biophysica acta.
[20] M. Malone,et al. Neurochemical changes in white matter. Aged human brain and Alzheimer's disease. , 1985, Archives of neurology.
[21] Gary Aston-Jones,et al. Age-impaired impulse flow from nucleus basalis to cortex , 1985, Nature.
[22] P. Yeagle. Cholesterol and the cell membrane. , 1985, Biochimica et biophysica acta.
[23] R. Epand,et al. Modulation of myelin basic protein-induced aggregation and fusion of liposomes by cholesterol, aliphatic aldehydes and alkanes. , 1986, Biochimica et biophysica acta.
[24] A. Brun,et al. A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study , 1986, Annals of neurology.
[25] B. Halliwell,et al. Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts. , 1986, Archives of biochemistry and biophysics.
[26] P. Goldman-Rakic,et al. Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex. , 1986, Science.
[27] V. Swayze,et al. Two Hemispheres—One Brain: Functions of the Corpus Callosum , 1987 .
[28] B. Brody,et al. Sequence of Central Nervous System Myelination in Human Infancy. I. An Autopsy Study of Myelination , 1987, Journal of neuropathology and experimental neurology.
[29] A Brun,et al. White matter changes in dementia of Alzheimer's type. Biochemical and neuropathological correlates. , 1988, Brain : a journal of neurology.
[30] R. Mahley,et al. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. , 1988, Science.
[31] H. Kinney,et al. Sequence of Central Nervous System Myelination in Human Infancy. II. Patterns of Myelination in Autopsied Infants , 1988, Journal of neuropathology and experimental neurology.
[32] S. Monte. Disproportionate Atrophy of Cerebral White Matter in Chronic Alcoholics , 1988 .
[33] J. Growdon,et al. Neuropathological distinction between Parkinson's dementia and Parkinson's plus Alzheimer's disease , 1989, Annals of neurology.
[34] S. M. Sumi,et al. Phenotypic heterogeneity in familial alzheimer's disease: A study of 24 kindreds , 1989, Annals of neurology.
[35] A. Wallin,et al. Decreased myelin lipids in Alzheimer's disease and vascular dementia , 1989, Acta neurologica Scandinavica.
[36] S. M. de la Monte,et al. Quantitation of cerebral atrophy in preclinical and end‐stage alzheimer's disease , 1989, Annals of neurology.
[37] J. Morrison,et al. Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: II. Primary and secondary visual cortex , 1990, The Journal of comparative neurology.
[38] M M Mesulam,et al. Large‐scale neurocognitive networks and distributed processing for attention, language, and memory , 1990, Annals of neurology.
[39] P. Rakić,et al. Cytological and quantitative characteristics of four cerebral commissures in the rhesus monkey , 1990, The Journal of comparative neurology.
[40] Kevin Cox,et al. Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: I. Superior frontal and inferior temporal cortex , 1990, The Journal of comparative neurology.
[41] D. McLachlan,et al. Intramuscular desferrioxamine in patients with Alzheimer's disease , 1991, The Lancet.
[42] W. Markesbery,et al. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[43] Peter Davies,et al. Identification of normal and pathological aging in prospectively studied nondemented elderly humans , 1992, Neurobiology of Aging.
[44] C. Morris,et al. Histochemical distribution of non-haem iron in the human brain. , 1992, Acta anatomica.
[45] L. Herbette,et al. Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol , 1992, Neurobiology of Aging.
[46] W. Meier-Ruge,et al. Age‐Related White Matter Atrophy in the Human Brain , 1992, Annals of the New York Academy of Sciences.
[47] A. Hofman,et al. Epidemiology of Alzheimer's disease. , 1992, Epidemiologic reviews.
[48] H. Persson,et al. Myelinated nerve fibres in the CNS , 1993, Progress in Neurobiology.
[49] R. Floyd,et al. The Role of Metal Ions in Oxidative Processes and Aging , 1993, Toxicology and industrial health.
[50] P. Mecocci,et al. Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain , 1993, Annals of neurology.
[51] L. Ignarro,et al. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. , 1993, Journal of immunology.
[52] M. Albert,et al. Neuropsychological and neurophysiological changes in healthy adult humans across the age range , 1993, Neurobiology of Aging.
[53] A. L. Watson,et al. In vitro polymerization of oxidized tau into filaments , 1993, Brain Research.
[54] M. Carson,et al. Insulin-like growth factor I increases brain growth and central nervous system myelination in tTransgenic mice , 1993, Neuron.
[55] T. Kemper,et al. Neuroanatomical and neuropathological changes during aging and dementia. , 1994 .
[56] B. Pakkenberg,et al. No global neocortical nerve cell loss in brains from patients with senile dementia of Alzheimer's type , 1994, Neurobiology of Aging.
[57] E. Änggård. Nitric oxide: mediator, murderer, and medicine , 1994, The Lancet.
[58] G. Bartzokis,et al. In vivo MR evaluation of age-related increases in brain iron. , 1994, AJNR. American journal of neuroradiology.
[59] C. Gottfries,et al. Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early‐Onset Form (Type I) and Demyelination in Late‐Onset Form (Type II) , 1994, Journal of neurochemistry.
[60] J. Troncoso,et al. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease , 1994, The Lancet.
[61] Jim Mintz,et al. In vivo evaluation of brain iron in Alzheimer's disease and normal subjects using MRI , 1994, Biological Psychiatry.
[62] F. Benes,et al. Myelination of a key relay zone in the hippocampal formation occurs in the human brain during childhood, adolescence, and adulthood. , 1994, Archives of general psychiatry.
[63] B. Juurlink,et al. Oligodendroglial precursor cell susceptibility to hypoxia is related to poor ability to cope with reactive oxygen species , 1995, Brain Research.
[64] W. D. Ehmann,et al. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease , 1995, Neurology.
[65] F. Schroeder,et al. Cholesterol domains in biological membranes. , 1995, Molecular membrane biology.
[66] R. S. Sohal,et al. Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies. , 1995, Free radical biology & medicine.
[67] J. Assouline,et al. Electrically evoked auditory brainstem response in peripherally myelin-deficient mice , 1995, Hearing Research.
[68] H. Vinters,et al. Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes , 1995, Neuroscience.
[69] H. Braak,et al. Close-meshed prevalence rates of different stages as a tool to uncover the rate of Alzheimer's disease-related neurofibrillary changes , 1995, Neuroscience.
[70] S. LeVine,et al. The distribution of iron in the brain: a phylogenetic analysis using iron histochemistry. , 1996, Brain research. Developmental brain research.
[71] J. Connor,et al. The expression of ferritin subunits and iron in oligodendrocytes in neonatal porcine brains. , 1996, Developmental neuroscience.
[72] D. Perl,et al. Evidence of neuronal oxidative damage in Alzheimer's disease. , 1996, The American journal of pathology.
[73] V Hachinski,et al. Diffuse vacuolization (spongiosis) and arteriolosclerosis in the frontal white matter occurs in vascular dementia. , 1996, Archives of neurology.
[74] Rita Y. Emmerson,et al. Life Span Changes in Electrophysiological Measures of Inhibition , 1996, Brain and Cognition.
[75] C. Gottfries,et al. Membrane Components Separate Early-Onset Alzheimer's Disease From Senile Dementia of the Alzheimer Type , 1996, International Psychogeriatrics.
[76] J. Connor,et al. Relationship of iron to oligondendrocytes and myelination , 1996 .
[77] D. Salmon,et al. Association of dementia severity with cortical gray matter and abnormal white matter volumes in dementia of the Alzheimer type. , 1996, Archives of neurology.
[78] C. Morris,et al. Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin. , 1996, Biochimica et biophysica acta.
[79] B. Pakkenberg,et al. Age-Induced White Matter Changes in the Human Brain: A Stereological Investigation , 1997, Neurobiology of Aging.
[80] C. Cotman,et al. β‐Amyloid Neurotoxicity In Vitro: Evidence of Oxidative Stress but Not Protection by Antioxidants , 1997, Journal of neurochemistry.
[81] J. Garcìa,et al. Pathogenesis of leukoaraiosis: a review. , 1997, Stroke.
[82] G. Bartzokis,et al. MR evaluation of age-related increase of brain iron in young adult and older normal males. , 1997, Magnetic resonance imaging.
[83] U. Igbavboa,et al. Lipid Binding to Amyloid β‐Peptide Aggregates: Preferential Binding of Cholesterol as Compared with Phosphatidylcholine and Fatty Acids , 1997, Journal of neurochemistry.
[84] Kenneth J. Smith,et al. Conduction in Segmentally Demyelinated Mammalian Central Axons , 1997, The Journal of Neuroscience.
[85] M. Ghandour,et al. Oligodendrocytes express different isoforms of β‐amyloid precursor protein in chemically defined cell culture conditions: In situ hybridization and immunocytochemical detection , 1997, Journal of neuroscience research.
[86] B. Juurlink. Response of Glial Cells to Ischemia: Roles of Reactive Oxygen Species and Glutathione , 1997, Neuroscience & Biobehavioral Reviews.
[87] R. Miledi,et al. Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[88] H. Braak,et al. Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories , 1997, Neurobiology of Aging.
[89] D. Hanger,et al. Oxidative Stress Induces Dephosphorylation of τ in Rat Brain Primary Neuronal Cultures , 1997 .
[90] M Takasaki,et al. Increased water diffusion in cerebral white matter in Alzheimer's disease. , 1997, Gerontology.
[91] P. Huttenlocher,et al. Regional differences in synaptogenesis in human cerebral cortex , 1997, The Journal of comparative neurology.
[92] U. Igbavboa,et al. Transbilayer Distribution of Cholesterol Is Modified in Brain Synaptic Plasma Membranes of Knockout Mice Deficient in the Low‐Density Lipoprotein Receptor, Apolipoprotein E, or Both Proteins , 1997, Journal of neurochemistry.
[93] W R Markesbery,et al. Oxidative stress hypothesis in Alzheimer's disease. , 1997, Free radical biology & medicine.
[94] A. Bosio,et al. Myelin glycolipids and their functions , 1997, Current Opinion in Neurobiology.
[95] G. Bartzokis,et al. Relationship between blood pressure and subcortical lesions in healthy elderly people. , 1998, Stroke.
[96] R. Kikinis,et al. White matter changes with normal aging , 1998, Neurology.
[97] S. Cadenas,et al. The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach , 1998, Journal of Comparative Physiology B.
[98] M. Garrido,et al. Evidence of altered central nervous system development in infants with iron deficiency anemia at 6 mo: delayed maturation of auditory brainstem responses. , 1998, The American journal of clinical nutrition.
[99] T. Kachi,et al. Auditory and visual event-related potentials and flash visual evoked potentials in Alzheimer's disease: correlations with Mini-Mental State Examination and Raven's Coloured Progressive Matrices , 1998, Journal of the Neurological Sciences.
[100] Reinhold Schmidt,et al. Pathophysiologic Mechanisms in the Development of Age-Related White Matter Changes of the Brain , 1998, Dementia and Geriatric Cognitive Disorders.
[101] Xudong Huang,et al. Dramatic Aggregation of Alzheimer Aβ by Cu(II) Is Induced by Conditions Representing Physiological Acidosis* , 1998, The Journal of Biological Chemistry.
[102] Joseph J. Volpe,et al. Maturation-Dependent Vulnerability of Oligodendrocytes to Oxidative Stress-Induced Death Caused by Glutathione Depletion , 1998, The Journal of Neuroscience.
[103] T. Kudo,et al. White matter changes in the gerbil brain under chronic cerebral hypoperfusion. , 1998, Stroke.
[104] P. Riederer,et al. In Vitro Studies of Ferritin Iron Release and Neurotoxicity , 1998, Journal of neurochemistry.
[105] J. Mcdonald,et al. Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity , 1998, Nature Medicine.
[106] S. Bondy,et al. Promotion of transition metal-induced reactive oxygen species formation by β-amyloid , 1998, Brain Research.
[107] J. Connor,et al. Abnormal localization of iron regulatory protein in Alzheimer's disease , 1998, Brain Research.
[108] P. Davidson,et al. Prenatal methylmercury exposure and children: neurologic, developmental, and behavioral research. , 1998, Environmental health perspectives.
[109] F Lepore,et al. Interhemispheric disconnection syndrome in Alzheimer's disease. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[110] Bruce A. Yankner,et al. Aging renders the brain vulnerable to amyloid β-protein neurotoxicity , 1998, Nature Medicine.
[111] M N Rossor,et al. Presymptomatic cognitive deficits in individuals at risk of familial Alzheimer's disease. A longitudinal prospective study. , 1998, Brain : a journal of neurology.
[112] R. Nieuwenhuys,et al. The Central Nervous System of Vertebrates , 1997, Springer Berlin Heidelberg.
[113] M. Beal,et al. The neurotoxicity of amyloid beta protein in aged primates. , 1998, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[114] O. Salonen,et al. Gelsolin‐related spinal and cerebral amyloid angiopathy , 1999, Annals of neurology.
[115] K. Berman,et al. Context-dependent, neural system-specific neurophysiological concomitants of ageing: mapping PET correlates during cognitive activation. , 1999, Brain : a journal of neurology.
[116] J. Wettstein,et al. White matter ischaemia , 1999, Brain Research Reviews.
[117] J. Trojanowski,et al. The Levels of Soluble versus Insoluble Brain Aβ Distinguish Alzheimer's Disease from Normal and Pathologic Aging , 1999, Experimental Neurology.
[118] M. Berry,et al. In vivo actions of fibroblast growth factor‐2 and insulin‐like growth factor‐I on oligodendrocyte development and myelination in the central nervous system , 1999, Journal of neuroscience research.
[119] C. Haass,et al. Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture* , 1999, The Journal of Biological Chemistry.
[120] C. Glabe,et al. Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence. , 1999, Bioorganic & medicinal chemistry letters.
[121] T. Crow,et al. Fiber content of the fornix in schizophrenia: lack of evidence for a primary limbic encephalopathy. , 1999, The American journal of psychiatry.
[122] E. Gould,et al. Learning enhances adult neurogenesis in the hippocampal formation , 1999, Nature Neuroscience.
[123] P. Hof,et al. Preservation of Prefrontal Cortical Volume in Behaviorally Characterized Aged Macaque Monkeys , 1999, Experimental Neurology.
[124] J M Fuster,et al. Synopsis of function and dysfunction of the frontal lobe , 1999, Acta psychiatrica Scandinavica. Supplementum.
[125] S. Bondy,et al. The stabilization of ferrous iron by a toxic β-amyloid fragment and by an aluminum salt , 1999, Brain Research.
[126] U. Igbavboa,et al. Recent advances in brain cholesterol dynamics: Transport, domains, and Alzheimer's disease , 1999, Lipids.
[127] A. Rodríguez-Peña,et al. Oligodendrocyte development and thyroid hormone. , 1999, Journal of neurobiology.
[128] W R Markesbery,et al. The magnitude of brain lipid peroxidation correlates with the extent of degeneration but not with density of neuritic plaques or neurofibrillary tangles or with APOE genotype in Alzheimer's disease patients. , 1999, The American journal of pathology.
[129] Sarah Tomlin,et al. Microtechnology: Laying it on thick , 1999, Nature.
[130] Ramesh Srinivasan,et al. Spatial structure of the human alpha rhythm: global correlation in adults and local correlation in children , 1999, Clinical Neurophysiology.
[131] J. Sloane,et al. Increased microglial activation and protein nitration in white matter of the aging monkey☆ , 1999, Neurobiology of Aging.
[132] M. Xi,et al. Changes in the axonal conduction velocity of pyramidal tract neurons in the aged cat , 1999, Neuroscience.
[133] G. Bartzokis,et al. Magnetic resonance imaging evidence of “silent” cerebrovascular toxicity in cocaine dependence , 1999, Biological Psychiatry.
[134] H. Braak,et al. Temporal Sequence of Alzheimer’s Disease-Related Pathology , 1999 .
[135] D. Selkoe,et al. Translating cell biology into therapeutic advances in Alzheimer's disease , 1999, Nature.
[136] H. Braak,et al. Age-related progression of tau pathology in brains of baboons , 2000, Neurobiology of Aging.
[137] Alan Peters,et al. The effects of aging on the frequency of nerve fibers in rhesus monkey striate cortex , 2000, Neurobiology of Aging.
[138] A. Fagan,et al. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[139] M. Mesulam,et al. A Plasticity‐Based Theory of the Pathogenesis of Alzheimer's Disease , 2000, Annals of the New York Academy of Sciences.
[140] G. Bartzokis,et al. In vivo evaluation of brain iron in Alzheimer disease using magnetic resonance imaging. , 2000, Archives of general psychiatry.
[141] H. Braak,et al. Sequence of Aβ‐Protein Deposition in the Human Medial Temporal Lobe , 2000 .
[142] J. de Vellis,et al. Dietary iron and the integrity of the developing rat brain: a study with the artificially-reared rat pup. , 2000, Cellular and molecular biology.
[143] C. Cotman,et al. Ultrastructural analyses of β-amyloid in the aged dog brain: Neuronal β-amyloid is localized to the plasma membrane , 2000, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[144] J. Mazziotta,et al. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[145] Xudong Huang,et al. Evidence that the β-Amyloid Plaques of Alzheimer's Disease Represent the Redox-silencing and Entombment of Aβ by Zinc* , 2000, The Journal of Biological Chemistry.
[146] A. D'ercole,et al. Insulin‐like growth factor‐I (IGF‐I) protects myelination from undernutritional insult: Studies of transgenic mice overexpressing IGF‐I in brain , 2000, Journal of neuroscience research.
[147] S. Carlton,et al. Peripheral glutamate release in the hindpaw following low and high intensity sciatic stimulation , 2000, Neuroreport.
[148] P. Ye,et al. Insulin-Like Growth Factor-1 Inhibits Mature Oligodendrocyte Apoptosis during Primary Demyelination , 2000, The Journal of Neuroscience.
[149] J. Sastre,et al. Mitochondria, oxidative stress and aging , 2000, Free radical research.
[150] V. Challa,et al. Cerebrovascular Pathology in Alzheimer's Disease and Leukoaraiosis , 2000, Annals of the New York Academy of Sciences.
[151] V. Papadopoulos,et al. Pathways of Neurosteroid Biosynthesis in Cell Lines from Human Brain , 2000, Journal of neurochemistry.
[152] M. Smith,et al. Oxidative stress in Alzheimer's disease. , 2000, Biochimica et biophysica acta.
[153] Alan C. Evans,et al. Growth patterns in the developing brain detected by using continuum mechanical tensor maps , 2000, Nature.
[154] P. Riederer,et al. Transition metal-mediated glycoxidation accelerates cross-linking of beta-amyloid peptide. , 2000, European journal of biochemistry.
[155] H. Braak,et al. Filamentous Tau Pathology in Nerve Cells, Astrocytes, and Oligodendrocytes of Aged Baboons , 2000, Journal of neuropathology and experimental neurology.
[156] Alan Peters,et al. Effects of aging on myelinated nerve fibers in monkey primary visual cortex , 2000, The Journal of comparative neurology.
[157] J. Townsend,et al. Normal brain development and aging: quantitative analysis at in vivo MR imaging in healthy volunteers. , 2000, Radiology.
[158] L. Schmued,et al. Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain , 2000, Brain Research.
[159] A. Bush,et al. Oxidative processes in Alzheimer's disease: the role of Aβ-metal interactions , 2000, Experimental Gerontology.
[160] K. Bedi,et al. Exposure of rats to a high but not low dose of ethanol during early postnatal life increases the rate of loss of optic nerve axons and decreases the rate of myelination , 2000, Journal of anatomy.
[161] G. Alonso. Prolonged corticosterone treatment of adult rats inhibits the proliferation of oligodendrocyte progenitors present throughout white and gray matter regions of the brain , 2000, Glia.
[162] J. Kuret,et al. Oxidative regulation of fatty acid-induced tau polymerization. , 2000, Biochemistry.
[163] Xudong Huang,et al. Metal Chelation as a Potential Therapy for Alzheimer's Disease , 2000, Annals of the New York Academy of Sciences.
[164] D. Butterfield,et al. Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity. , 2000, Journal of structural biology.
[165] A. McKee,et al. Serum amyloid A in Alzheimer's disease brain is predominantly localized to myelin sheaths and axonal membrane , 2000, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[166] T. Miyaoka,et al. Dementia of Alzheimer type with and without multiple lacunar infarctions: Evaluation of white matter lesions , 2000, Neuropathology : official journal of the Japanese Society of Neuropathology.
[167] H. Braak,et al. Vulnerability of Select Neuronal Types to Alzheimer's Disease , 2000, Annals of the New York Academy of Sciences.
[168] R. McKinnon,et al. Lead exposure delays the differentiation of oligodendroglial progenitors in vitro. , 2001, Toxicology and applied pharmacology.
[169] C. Dreyfus,et al. Neuronal signals regulate neurotrophin expression in oligodendrocytes of the basal forebrain , 2001, Glia.
[170] E. Baulieu,et al. Neurosteroids: recent findings , 2001, Brain Research Reviews.
[171] W. Singer,et al. Dynamic predictions: Oscillations and synchrony in top–down processing , 2001, Nature Reviews Neuroscience.
[172] D. Davies,et al. Neurodegenerative Changes Associated with β-Amyloid Deposition in the Brains of Mice Carrying Mutant Amyloid Precursor Protein and Mutant Presenilin-1 Transgenes , 2001, Experimental Neurology.
[173] C. Palmer,et al. Hypoxic/ischemic insult alters ferritin expression and myelination in neonatal rat brains , 2001 .
[174] D. Burn,et al. Multiple system atrophy: cellular and molecular pathology , 2001, Molecular pathology : MP.
[175] D. Allsop,et al. New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps. , 2001, Free radical biology & medicine.
[176] G. Annoni,et al. The hemochromatosis gene affects the age of onset of sporadic Alzheimer’s disease , 2001, Neurobiology of Aging.
[177] J. Dietschy,et al. Cholesterol metabolism in the brain , 2001, Current opinion in lipidology.
[178] H. Braak,et al. Gender and age modify the association between APOE and AD-related neuropathology , 2001, Neurology.
[179] Development: Ear see rescue , 2001, Nature Reviews Neuroscience.
[180] C. Masters,et al. Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice , 2001, Neuron.
[181] M. J. Wade,et al. Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. , 2001, Archives of neurology.
[182] Ashley I. Bush,et al. Redox-active iron mediates amyloid-β toxicity , 2001 .
[183] D. Sparks,et al. Cholesterol Accumulates in Senile Plaques of Alzheimer Disease Patients and in Transgenic APPsw Mice , 2001, Journal of neuropathology and experimental neurology.
[184] D. Selkoe. Alzheimer's disease: genes, proteins, and therapy. , 2001, Physiological reviews.
[185] S. Dunlop,et al. Repeated prenatal corticosteroid administration delays myelination of the corpus callosum in fetal sheep , 2001, International Journal of Developmental Neuroscience.
[186] C. Masters,et al. Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits* , 2001, The Journal of Biological Chemistry.
[187] M. Goldberg,et al. Amyloid-β Peptides Are Cytotoxic to Oligodendrocytes , 2001, The Journal of Neuroscience.
[188] J. López. Neurodegenerative disorders: A-beta, tau and the fabrication of tangles , 2001, Nature Reviews Neuroscience.
[189] W. Schlote,et al. Giant cell arteritis in a 19-year-old woman associated with vertebral artery aneurysm and subarachnoid hemorrhage. , 2001, Clinical neuropathology.
[190] J. Martinerie,et al. The brainweb: Phase synchronization and large-scale integration , 2001, Nature Reviews Neuroscience.
[191] G. Bartzokis,et al. Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study. , 2001, Archives of general psychiatry.
[192] B. Winblad,et al. Alzheimer's disease : advances in etiology, pathogenesis, and therapeutics , 2001 .
[193] K. Jellinger,et al. Problems of cell death in neurodegeneration and Alzheimer's Disease. , 2001, Journal of Alzheimer's disease : JAD.
[194] J. Marx. Bad for the Heart, Bad For the Mind? , 2001, Science.
[195] O. Bertrand,et al. Oscillatory Synchrony between Human Extrastriate Areas during Visual Short-Term Memory Maintenance , 2001, The Journal of Neuroscience.
[196] D. Morath,et al. Iron modulates the differentiation of a distinct population of glial precursor cells into oligodendrocytes. , 2001, Developmental biology.
[197] B. Winblad,et al. On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells , 2001, Neuroscience Letters.
[198] C. Elger,et al. Human memory formation is accompanied by rhinal–hippocampal coupling and decoupling , 2001, Nature Neuroscience.
[199] T. Ueda,et al. The relationship between the aggregational state of the amyloid‐β peptides and free radical generation by the peptides , 2001, Journal of neurochemistry.
[200] R. Scott,et al. Is hemochromatosis a risk factor for Alzheimer's disease? , 2001, Journal of Alzheimer's disease : JAD.
[201] G Ratcliff,et al. Patterns of cognitive decline in presymptomatic Alzheimer disease: a prospective community study. , 2001, Archives of general psychiatry.
[202] Gert Lubec,et al. Decreased brain levels of 2′,3′-cyclic nucleotide-3′-phosphodiesterase in Down syndrome and Alzheimer’s disease , 2001, Neurobiology of Aging.
[203] C. Göritz,et al. CNS synaptogenesis promoted by glia-derived cholesterol. , 2001, Science.
[204] M. O’Sullivan,et al. Incidence of ALS in Italy , 2001, Neurology.
[205] A Compston,et al. A role for oligodendrocyte‐derived IGF‐1 in trophic support of cortical neurons , 2001, Glia.
[206] U. Beisiegel,et al. Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain. , 2002, Archives of neurology.
[207] C. Masters,et al. Overexpression of Alzheimer's Disease Amyloid-β Opposes the Age-dependent Elevations of Brain Copper and Iron* , 2002, The Journal of Biological Chemistry.
[208] George Bartzokis,et al. Ambulatory blood pressure and brain atrophy in the healthy elderly , 2002, Neurology.
[209] HR Waterham,et al. Inherited disorders of cholesterol biosynthesis , 2002, Clinical genetics.
[210] Arto Mannermaa,et al. Apolipoprotein E 4 Allele, Elevated Midlife Total Cholesterol Level, and High Midlife Systolic Blood Pressure Are Independent Risk Factors for Late-Life Alzheimer Disease , 2002, Annals of Internal Medicine.
[211] G. Kress,et al. The Relationship between Intracellular Free Iron and Cell Injury in Cultured Neurons, Astrocytes, and Oligodendrocytes , 2002, The Journal of Neuroscience.
[212] H. Hayashi,et al. Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice , 2002, Neuroreport.
[213] T. Iwamoto,et al. Demonstration and distribution of tau‐positive glial coiled body‐like structures in white matter and white matter threads in early onset Alzheimer’s disease , 2002, Neuropathology : official journal of the Japanese Society of Neuropathology.
[214] J. Trojanowski,et al. Repetitive Mild Brain Trauma Accelerates Aβ Deposition, Lipid Peroxidation, and Cognitive Impairment in a Transgenic Mouse Model of Alzheimer Amyloidosis , 2002, The Journal of Neuroscience.
[215] J. Babb,et al. Age-related total gray matter and white matter changes in normal adult brain. Part I: volumetric MR imaging analysis. , 2002, AJNR. American journal of neuroradiology.
[216] Yu-Min Kuo,et al. Increased Aβ Peptides and Reduced Cholesterol and Myelin Proteins Characterize White Matter Degeneration in Alzheimer's Disease† , 2002 .
[217] Alan Peters,et al. Aging and the myelinated fibers in prefrontal cortex and corpus callosum of the monkey , 2002, The Journal of comparative neurology.
[218] V. Papadopoulos,et al. Function of β‐amyloid in cholesterol transport: a lead to neurotoxicity , 2002 .
[219] R. Mayeux,et al. The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function , 2002, Neurology.
[220] H. Braak,et al. Phases of Aβ-deposition in the human brain and its relevance for the development of AD , 2002, Neurology.
[221] P. Zandi,et al. Reduced incidence of AD with NSAID but not H2 receptor antagonists: The Cache County Study , 2002, Neurology.
[222] B. Winblad,et al. Statins in the Prevention and Treatment of Alzheimer Disease , 2002, Alzheimer disease and associated disorders.
[223] W. K. Cullen,et al. Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo , 2002, Nature.
[224] D. Schenk. Amyloid-β immunotherapy for Alzheimer's disease: the end of the beginning , 2002, Nature Reviews Neuroscience.
[225] H. Bratzke,et al. Incidence of axonal injury in human brain tissue , 2002, Acta Neuropathologica.
[226] Jaakko Tuomilehto,et al. The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study. , 2002 .
[227] Y. Koshino,et al. Apoptosis of astrocytes with enhanced lysosomal activity and oligodendrocytes in white matter lesions in Alzheimer's disease , 2002, Neuropathology and applied neurobiology.
[228] K. Heilman,et al. Relative Frequencies of Alzheimer Disease, Lewy Body, Vascular and Frontotemporal Dementia, and Hippocampal Sclerosis in the State of Florida Brain Bank , 2002, Alzheimer disease and associated disorders.
[229] J. Joseph,et al. Amyloid-β and τ serve antioxidant functions in the aging and Alzheimer brain , 2002 .
[230] S. Wisniewski,et al. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment , 2002, Annals of neurology.
[231] D. Okonkwo,et al. Caspase-3-mediated cleavage of amyloid precursor protein and formation of amyloid Beta peptide in traumatic axonal injury. , 2002, Journal of neurotrauma.
[232] H. Lassmann,et al. Endoplasmic Reticulum Stress in PLP‐Overexpressing Transgenic Rats: Gray Matter Oligodendrocytes Are More Vulnerable than White Matter Oligodendrocytes , 2002, Journal of neuropathology and experimental neurology.
[233] D. Allsop,et al. Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease. , 2002 .
[234] M. Noble,et al. Oligodendrocyte precursor cells from different brain regions express divergent properties consistent with the differing time courses of myelination in these regions. , 2002, Developmental biology.
[235] H. Fillit. The role of hormone replacement therapy in the prevention of Alzheimer disease. , 2002, Archives of internal medicine.
[236] B. Wolozin,et al. Cholesterol and Alzheimer's disease. , 2002, Biochemical Society transactions.
[237] K. Zou,et al. Cholesterol‐dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons , 2002, Journal of neurochemistry.
[238] F. Jessen,et al. 24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. , 2002, Journal of psychiatric research.
[239] J. Trojanowski,et al. Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease. , 2002, Archives of neurology.
[240] W. M. van der Flier,et al. Magnetization transfer imaging in normal aging, mild cognitive impairment, and Alzheimer's disease , 2002, Annals of neurology.
[241] J. Hardy,et al. The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics , 2009 .
[242] U. Igbavboa,et al. Brain membrane cholesterol domains, aging and amyloid beta-peptides , 2002, Neurobiology of Aging.
[243] Epidemiology of Dementia in Down's Syndrome , 2002 .
[244] G. Ojemann,et al. Anatomic subdivisions in human temporal cortical neuronal activity related to recent verbal memory , 2002, Nature Neuroscience.
[245] F. Craik,et al. Lapses of Intention and Performance Variability Reveal Age-Related Increases in Fluctuations of Executive Control , 2002, Brain and Cognition.
[246] H. Damasio,et al. Humans and great apes share a large frontal cortex , 2002, Nature Neuroscience.
[247] K. Zou,et al. A Novel Function of Monomeric Amyloid β-Protein Serving as an Antioxidant Molecule against Metal-Induced Oxidative Damage , 2002, The Journal of Neuroscience.
[248] Jim Mintz,et al. Brain maturation may be arrested in chronic cocaine addicts , 2002, Biological Psychiatry.
[249] Lars-Olof Wahlund,et al. Postmortem MRI and Histopathology of White Matter Changes in Alzheimer Brains , 2002, Dementia and Geriatric Cognitive Disorders.
[250] J. Schulz,et al. Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes , 2002, The Journal of cell biology.
[251] N. Greig,et al. Alzheimer’s disease drug discovery targeted to the APP mRNA 5′Untranslated region , 2002, Journal of Molecular Neuroscience.
[252] C. Yip,et al. Aβ42-Peptide Assembly on Lipid Bilayers , 2002 .
[253] Á. Pascual-Leone,et al. Effects of Early Undernutrition on the Brain Insulin‐Like Growth Factor‐I System , 2002, Journal of neuroendocrinology.
[254] Yulin Ge,et al. Age-related total gray matter and white matter changes in normal adult brain. Part II: quantitative magnetization transfer ratio histogram analysis. , 2002, AJNR. American journal of neuroradiology.
[255] B. Ames,et al. Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[256] Xianlin Han,et al. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis , 2002, Journal of neurochemistry.
[257] George Bartzokis,et al. Schizophrenia: Breakdown in the Well-regulated Lifelong Process of Brain Development and Maturation , 2002, Neuropsychopharmacology.
[258] C. Haass,et al. Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts , 2003, The Journal of cell biology.
[259] H. Braak,et al. Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. , 2003, Archives of neurology.
[260] B. Pakkenberg,et al. Aging and the human neocortex , 2003, Experimental Gerontology.
[261] G. Bartzokis,et al. White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study. , 2003, Archives of neurology.
[262] Pamela L. Follett,et al. Mature myelin basic protein‐expressing oligodendrocytes are insensitive to kainate toxicity , 2003, Journal of neuroscience research.
[263] Suzanne E. Welcome,et al. Mapping cortical change across the human life span , 2003, Nature Neuroscience.
[264] Colin J Barrow,et al. Cholesterol is necessary both for the toxic effect of Aβ peptides on vascular smooth muscle cells and for Aβ binding to vascular smooth muscle cell membranes , 2003, Journal of neurochemistry.
[265] G. Eckert,et al. Statin effects on cholesterol micro-domains in brain plasma membranes. , 2003, Biochemical pharmacology.
[266] I. Mackenzie. Senile plaques do not progressively accumulate with normal aging , 2004, Acta Neuropathologica.
[267] G. Bartzokis,et al. Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical “disconnection” in aging and Alzheimer’s disease , 2004, Neurobiology of Aging.
[268] George Bartzokis,et al. Quadratic trajectories of brain myelin content: unifying construct for neuropsychiatric disorders , 2004, Neurobiology of Aging.
[269] H. Wiśniewski,et al. Spectrum of morphological appearance of amyloid deposits in Alzheimer's disease , 2004, Acta Neuropathologica.
[270] G. Rouser,et al. Curvilinear regression course of human brain lipid composition changes with age , 1968, Lipids.
[271] P. Morell,et al. Origin of cholesterol in myelin , 1996, Neurochemical Research.