In vivo effects of single or combined topical neuroprotective and regenerative agents on degeneration of retinal ganglion cells in rat optic nerve crush model

[1]  L. Mesentier-Louro,et al.  Nerve Growth Factor Role on Retinal Ganglion Cell Survival and Axon Regrowth: Effects of Ocular Administration in Experimental Model of Optic Nerve Injury , 2018, Molecular Neurobiology.

[2]  Yan Jin,et al.  PD-1 is required to maintain stem cell properties in human dental pulp stem cells , 2018, Cell Death & Differentiation.

[3]  Xin-Yuan Fu,et al.  APP upregulation contributes to retinal ganglion cell degeneration via JNK3 , 2017, Cell Death & Differentiation.

[4]  Z. Ahmed,et al.  Caspases in retinal ganglion cell death and axon regeneration , 2017, Cell Death Discovery.

[5]  T. Oshitari,et al.  Mechanisms of Neuronal Cell Death in AGE-exposed Retinas - Research and Literature Review. , 2017, Current diabetes reviews.

[6]  T. Oshitari,et al.  Combination of Neuroprotective and Regenerative Agents for AGE-Induced Retinal Degeneration: In Vitro Study , 2017, BioMed research international.

[7]  Z. Wen,et al.  Neuroprotective effect of 4-(Phenylsulfanyl)butan-2-one on optic nerve crush model in rats. , 2016, Experimental eye research.

[8]  M. Vidal-Sanz,et al.  Apoptotic Retinal Ganglion Cell Death After Optic Nerve Transection or Crush in Mice: Delayed RGC Loss With BDNF or a Caspase 3 Inhibitor. , 2016, Investigative ophthalmology & visual science.

[9]  V. Gómez-Vicente,et al.  Neuroprotective Effect of Tauroursodeoxycholic Acid on N-Methyl-D-Aspartate-Induced Retinal Ganglion Cell Degeneration , 2015, PloS one.

[10]  V. Parisi,et al.  Treatment with citicoline eye drops enhances retinal function and neural conduction along the visual pathways in open angle glaucoma , 2015, Graefe's Archive for Clinical and Experimental Ophthalmology.

[11]  T. Oshitari,et al.  Altered Expression of NF-κB and SP1 after Exposure to Advanced Glycation End-Products and Effects of Neurotrophic Factors in AGEs Exposed Rat Retinas , 2015, Journal of diabetes research.

[12]  V. Parisi,et al.  A preliminary study of the neuroprotective role of citicoline eye drops in glaucomatous optic neuropathy , 2014, Indian journal of ophthalmology.

[13]  F. Bandello,et al.  In Vivo Evaluation of Retinal and Choroidal Structure in a Mouse Model of Long-Lasting Diabetes. Effect of Topical Treatment with Citicoline. , 2014 .

[14]  T. Oshitari,et al.  Increased Expression of c-Fos, c-Jun and c-Jun N-Terminal Kinase Associated with Neuronal Cell Death in Retinas of Diabetic Patients , 2014, Current eye research.

[15]  T. Oshitari,et al.  Increased expression of phosphorylated c-Jun and phosphorylated c-Jun N-terminal kinase associated with neuronal cell death in diabetic and high glucose exposed rat retinas , 2014, Brain Research Bulletin.

[16]  T. Oshitari,et al.  Neurite regeneration in adult rat retinas exposed to advanced glycation end-products and regenerative effects of neurotrophin-4 , 2013, Brain Research.

[17]  M. Fruttiger,et al.  Whole mount immunofluorescent staining of the neonatal mouse retina to investigate angiogenesis in vivo. , 2013, Journal of visualized experiments : JoVE.

[18]  S. Graham,et al.  TrkB Receptor Signalling: Implications in Neurodegenerative, Psychiatric and Proliferative Disorders , 2013, International journal of molecular sciences.

[19]  S. Masuda,et al.  Sodium tauroursodeoxycholate prevents paraquat-induced cell death by suppressing endoplasmic reticulum stress responses in human lung epithelial A549 cells. , 2013, Biochemical and biophysical research communications.

[20]  P. Fagone,et al.  Phosphatidylcholine and the CDP-choline cycle. , 2013, Biochimica et biophysica acta.

[21]  Y. Diao,et al.  Inhibition of Endoplasmic Reticulum Stress Improves Mouse Embryo Development , 2012, PloS one.

[22]  Kevin W Eliceiri,et al.  NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.

[23]  S. John,et al.  JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death , 2012, Neurobiology of Disease.

[24]  M. Gutiérrez-Fernández,et al.  CDP-choline treatment induces brain plasticity markers expression in experimental animal stroke , 2012, Neurochemistry International.

[25]  T. Oshitari,et al.  Effect of neurotrophin-4 on endoplasmic reticulum stress-related neuronal apoptosis in diabetic and high glucose exposed rat retinas , 2011, Neuroscience Letters.

[26]  J. Secades Citicoline: pharmacological and clinical review, 2010 update. , 2011, Revista de neurologia.

[27]  M. Russo,et al.  Ocular Application of Nerve Growth Factor Protects Degenerating Retinal Ganglion Cells in a Rat Model of Glaucoma , 2011, Journal of glaucoma.

[28]  P. Campochiaro,et al.  Constituents of bile, bilirubin and TUDCA, protect against oxidative stress‐induced retinal degeneration , 2011, Journal of neurochemistry.

[29]  S. Kügler,et al.  Long-Distance Axon Regeneration in the Mature Optic Nerve: Contributions of Oncomodulin, cAMP, and pten Gene Deletion , 2010, The Journal of Neuroscience.

[30]  S. Woo,et al.  Ursodeoxycholic acid and tauroursodeoxycholic acid suppress choroidal neovascularization in a laser-treated rat model. , 2010, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

[31]  V. Parisi,et al.  Experimental and clinical evidence of neuroprotection by nerve growth factor eye drops: Implications for glaucoma , 2009, Proceedings of the National Academy of Sciences.

[32]  T. Oshitari,et al.  Mitochondria- and caspase-dependent cell death pathway involved in neuronal degeneration in diabetic retinopathy , 2008, British Journal of Ophthalmology.

[33]  J. Saver Citicoline: update on a promising and widely available agent for neuroprotection and neurorepair. , 2008, Reviews in neurological diseases.

[34]  E. Huang,et al.  Trk receptors: roles in neuronal signal transduction. , 2003, Annual review of biochemistry.

[35]  G. Jerums,et al.  Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease. , 2003, Archives of biochemistry and biophysics.

[36]  M. Chao,et al.  Neurotrophins and their receptors: A convergence point for many signalling pathways , 2003, Nature Reviews Neuroscience.

[37]  T. Oshitari,et al.  Citicoline has a protective effect on damaged retinal ganglion cells in mouse culture retina , 2002, Neuroreport.

[38]  P. Fonlupt,et al.  Effects of cytidine-5' diphosphocholine on norepinephrine, dopamine and serotonin synthesis in various regions of the rat brain. , 1979, Archives internationales de pharmacodynamie et de therapie.