Objective assessment of postural stability in Parkinson's disease using mobile technology

A significant gap remains in the ability to effectively characterize postural instability in individuals with Parkinson's disease. Clinical evaluation of postural declines is largely subjective, whereas objective biomechanical approaches are expensive and time consuming, thus limiting clinical adoption. Recent advances in mobile devices present an opportunity to address the gap in the quantification of postural stability. The aim of this project was to determine whether kinematic data measured by hardware within a tablet device, a 3rd generation iPad, was of sufficient quantity and quality to characterize postural stability.

[1]  R B Stein,et al.  Application of tilt sensors in functional electrical stimulation. , 1996, IEEE transactions on rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.

[2]  Dominique Hansen,et al.  Exercise Assessment and Prescription in Patients With Type 2 Diabetes in the Private and Home Care Setting: Clinical Recommendations From AXXON (Belgian Physical Therapy Association) , 2013, Physical Therapy.

[3]  B M Nigg,et al.  A method for inverse dynamic analysis using accelerometry. , 1996, Journal of biomechanics.

[4]  J. Mehrholz,et al.  Immediate effects of speed-dependent treadmill training on gait parameters in early Parkinson's disease. , 2003, Archives of physical medicine and rehabilitation.

[5]  Sheldon R Simon,et al.  Quantification of human motion: gait analysis-benefits and limitations to its application to clinical problems. , 2004, Journal of biomechanics.

[6]  M S Redfern,et al.  A comparison of accelerometry and center of pressure measures during computerized dynamic posturography: a measure of balance. , 2011, Gait & posture.

[7]  P H Veltink,et al.  Detection of static and dynamic activities using uniaxial accelerometers. , 1996, IEEE transactions on rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society.

[8]  A. Beuter,et al.  Postural Sway and Effect of Levodopa in Early Parkinson's Disease , 2008, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[9]  F. Horak,et al.  Trunk accelerometry reveals postural instability in untreated Parkinson's disease. , 2011, Parkinsonism & related disorders.

[10]  Ann Ashburn,et al.  A meta‐analysis of six prospective studies of falling in Parkinson's disease , 2007, Movement disorders : official journal of the Movement Disorder Society.

[11]  Jay L. Alberts,et al.  Quantification of postural stability in older adults using mobile technology , 2014, Experimental Brain Research.

[12]  F. Horak,et al.  Postural sway as a marker of progression in Parkinson's disease: a pilot longitudinal study. , 2012, Gait & posture.

[13]  Alfons Schnitzler,et al.  High compliance with rotigotine transdermal patch in the treatment of idiopathic Parkinson's disease. , 2010, Parkinsonism & related disorders.

[14]  P. Veltink,et al.  Estimating orientation with gyroscopes and accelerometers. , 1999, Technology and health care : official journal of the European Society for Engineering and Medicine.

[15]  W. Koller,et al.  Falls and Parkinson's disease. , 1989, Clinical neuropharmacology.

[16]  Katy Mitchell,et al.  Gait and step training to reduce falls in Parkinson's disease. , 2005, NeuroRehabilitation.

[17]  M P Kadaba,et al.  Measurement of lower extremity kinematics during level walking , 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[18]  M. Morris Movement disorders in people with Parkinson disease: a model for physical therapy. , 2000, Physical therapy.

[19]  F. Horak,et al.  Effects of Parkinson's disease and levodopa on functional limits of stability. , 2008, Clinical biomechanics.

[20]  M. Baker,et al.  Is Self-Administration of Subcutaneous Immunoglobulin Therapy Safe in a Home Care Setting? An Evidence-Based Practice Journey , 2013, Home healthcare nurse.

[21]  R. Walker,et al.  Incidence and prediction of falls in Parkinson's disease: a prospective multidisciplinary study , 2002, Journal of neurology, neurosurgery, and psychiatry.

[22]  M H Granat,et al.  A practical gait analysis system using gyroscopes. , 1999, Medical engineering & physics.

[23]  Peter H Veltink,et al.  Accelerometer and rate gyroscope measurement of kinematics: an inexpensive alternative to optical motion analysis systems. , 2002, Journal of biomechanics.

[24]  Mikel Gray Context for practice: effectiveness of WOC specialty practice nursing in the home health care setting. , 2013, Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society.

[25]  Susan C. Miller,et al.  The role of hospice care in the nursing home setting. , 2002, Journal of palliative medicine.

[26]  P. Veltink Sensory feedback in artificial control of human mobility. , 1999, Technology and health care : official journal of the European Society for Engineering and Medicine.

[27]  A. Zwinderman,et al.  Prospective assessment of falls in Parkinson's disease , 2001, Journal of Neurology.

[28]  Jay Hertel,et al.  Systematic review of postural control and lateral ankle instability, part II: is balance training clinically effective? , 2008, Journal of athletic training.

[29]  M H Cole,et al.  Predictors of future falls in Parkinson disease , 2010, Neurology.

[30]  R. B. Davis,et al.  A gait analysis data collection and reduction technique , 1991 .

[31]  Yoav Ben-Shlomo,et al.  How common are complications of Parkinson's disease? , 2002, Journal of Neurology.

[32]  B. Bloem,et al.  Falls in the elderly. I. Identification of risk factors. , 2001, Wiener klinische Wochenschrift.

[33]  M. Morris,et al.  The reliability of three-dimensional kinematic gait measurements: a systematic review. , 2009, Gait & posture.

[34]  Age and Ageing Correlation of accelerometry with clinical balance tests in older fallers and non-fallers , 2009 .

[35]  Christopher Kennard,et al.  Eye movements in visual search indicate impaired saliency processing in Parkinson's disease , 2008, Progress in brain research.

[36]  Shinji Miyazaki,et al.  Comparison of the performance of 3D camera systems , 1995 .

[37]  B R Bloem,et al.  Falls in the elderly. II. Strategies for prevention. , 2001, Wiener klinische Wochenschrift.