Digital design and fabrication of customized mandible implant

Reconstruction of mandibular defects following severe trauma is one of the most challenging problems faced by today's maxillofacial reconstructive surgeons. Mandible plays a major role in the support of dental and para-dental structures like mastication, articulation, deglutition and respiration. Segmental Mandibular resections without reconstruction result in deviation of the mandible towards the resected side due to the unopposed pull of the remaining muscles, loss of function and significant cosmetic defect. With the advancement of current medical imaging technology such as Computer Tomography (CT) and Magnetic Resonance Imaging (MRI), and other technologies such as Computer Aided Design (CAD) and Additive Manufacturing, it is possible to design geometrical models and visualize the anatomical structures to obtained required information fabricate customized implants for each patients. This article presents the results of an on-going project in mandiblular reconstruction using Electron Beam Melting (EBM) additive manufacturing technology for mandibular reconstruction and surgery.

[1]  E H Greener,et al.  Studies of Ti alloys for dental castings. , 1989, Dental materials : official publication of the Academy of Dental Materials.

[2]  Abhay Pandit,et al.  Fabrication methods of porous metals for use in orthopaedic applications. , 2006, Biomaterials.

[3]  Martin Werner,et al.  CO2 laser milling of hard tissue , 2007, SPIE BiOS.

[4]  Gregori M Kurtzman CAD/CAM Implant Suprastructures: Accuracy, Durability and Precision , 2010 .

[5]  Emma Louise McGinley,et al.  Biocompatibility effects of indirect exposure of base-metal dental casting alloys to a human-derived three-dimensional oral mucosal model. , 2013, Journal of dentistry.

[6]  A Linney,et al.  A prospective study of computer-aided design and manufacture of titanium plate for cranioplasty and its clinical outcome. , 1999, British journal of neurosurgery.

[7]  Van Roekel Nb Prosthesis fabrication using electrical discharge machining. , 1992 .

[8]  J. Ciurana,et al.  Biomedical production of implants by additive electro-chemical and physical processes , 2012 .

[9]  Biswanath Doloi,et al.  Surface Characteristics of Titanium during ECM Process for Biomedical Applications , 2011 .

[10]  Chikahiro Ohkubo,et al.  The present status of dental titanium casting , 1998 .

[11]  Simion Bran,et al.  Silicone rubber mould cast polyethylmethacrylate-hydroxyapatite plate used for repairing a large skull defect. , 2006, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[12]  N B Van Roekel,et al.  Prosthesis fabrication using electrical discharge machining. , 1992, The International journal of oral & maxillofacial implants.

[13]  Lu Bingheng,et al.  Design and fabrication of custom mandible titanium tray based on rapid prototyping. , 2004, Medical engineering & physics.

[14]  J. Kruth,et al.  Benchmarking of different SLS/SLM processes as Rapid Manufacturing techniques , 2005 .

[15]  Schmitt Sm,et al.  Fabrication of titanium implant-retained restorations with nontraditional machining techniques. , 1995 .

[16]  D. F. Williams,et al.  The Williams dictionary of biomaterials , 1999 .

[17]  Dietmar W Hutmacher,et al.  Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. , 2004, Trends in biotechnology.

[18]  Zhijian Pei,et al.  Rotary Ultrasonic Machining of Dental Ceramics: A Preliminary Study on Subsurface Cracks , 2010 .

[19]  David C. Dunand,et al.  Processing of Titanium Foams , 2004 .

[20]  D. Williams,et al.  The Williams Dictionary of Biomaterials: L , 1999 .

[21]  Mohammed Rafiq Abdul Kadir,et al.  Manufacturing methods for machining micro pits of hip implant for metal-on-metal lubrication , 2012, 2012 International Conference on Biomedical Engineering (ICoBE).

[22]  Y Hotta,et al.  Development of fabrication system of prostheses using electric discharge machining. , 1993, Asian journal of aesthetic dentistry.

[23]  L. Froyen,et al.  Binding Mechanisms in Selective Laser Sintering and Selective Laser Melting , 2004 .

[24]  S M Schmitt,et al.  Fabrication of titanium implant-retained restorations with nontraditional machining techniques. , 1995, The International journal of prosthodontics.

[25]  C. Leroux,et al.  Bone growth in rapid prototyped porous titanium implants. , 2008, Journal of biomedical materials research. Part A.

[26]  Jean-Pierre Kruth,et al.  Digital manufacturing of biocompatible metal frameworks for complex dental prostheses by means of SLS/SLM , 2005 .

[27]  Emeka Nkenke,et al.  In vivo performance of selective electron beam-melted Ti-6Al-4V structures. , 2010, Journal of biomedical materials research. Part A.

[28]  George A Zarb,et al.  A comparison of the accuracy of fit of 2 methods for fabricating implant-prosthodontic frameworks. , 2007, The International journal of prosthodontics.

[29]  Torsten Jemt,et al.  Comparisons of precision of fit between cast and CNC-milled titanium implant frameworks for the edentulous mandible. , 2003, The International journal of prosthodontics.

[30]  S. Raman,et al.  A design for the additive manufacture of functionally graded porous structures with tailored mechanical properties for biomedical applications , 2011 .

[31]  J. Kruth,et al.  Selective laser melting of biocompatible metals for rapid manufacturing of medical parts , 2006 .

[32]  J Takahashi,et al.  Application of 18-8 stainless steel to dental cast crown. , 1981, The Journal of Osaka University Dental School.