Cardiac CT: state of the art for the detection of coronary arterial stenosis.

The recent evolution of multidetector computed tomography (CT) technology has substantially improved the ability of CT to visualize the heart and coronary arteries. After injection of contrast agent, relatively reliable imaging of the coronary arteries can be achieved, even though some restrictions are caused because the spatial and temporal resolutions are still somewhat limited. Several studies have shown that stenoses of the native coronary arteries can be detected with high sensitivity and specificity if image quality is adequate. More challenging situations include imaging of patients with stents and bypass grafts. Several clinical applications have been defined as "appropriate" and include the use of CT angiography in patients who have symptoms but who cannot exercise or who have an uninterpretable stress test result, or in patients with acute chest pain of intermediate likelihood for coronary artery disease but lack of electrocardiographic changes or myocardial enzyme elevations. It can be expected that further improvement of CT technology will help to more firmly establish the clinical role of CT coronary angiography and to explore further applications of this technique.

[1]  J. Blanc,et al.  Assessment of coronary artery stents by 16 slice computed tomography , 2005, Heart.

[2]  Brian O'Neil,et al.  The diagnostic accuracy of 64-slice computed tomography coronary angiography compared with stress nuclear imaging in emergency department low-risk chest pain patients. , 2007, Annals of emergency medicine.

[3]  Ulrich Baum,et al.  Usefulness of multidetector row spiral computed tomography with 64- x 0.6-mm collimation and 330-ms rotation for the noninvasive detection of significant coronary artery stenoses. , 2006, The American journal of cardiology.

[4]  S. Achenbach,et al.  Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography. , 2006, Journal of the American College of Cardiology.

[5]  Werner Moshage,et al.  Noninvasive coronary angiography by retrospectively ECG-gated multislice spiral CT. , 2000 .

[6]  Stephen Schroeder,et al.  Noninvasive detection of coronary lesions using 16-detector multislice spiral computed tomography technology: initial clinical results. , 2004, Journal of the American College of Cardiology.

[7]  W. Bautz,et al.  Coronary artery bypass graft (CABG) patency: assessment with high-resolution submillimeter 16-slice multidetector-row computed tomography (MDCT) versus coronary angiography. , 2006, European journal of radiology.

[8]  S. Achenbach,et al.  Value of electron-beam computed tomography for the noninvasive detection of high-grade coronary-artery stenoses and occlusions. , 1998, The New England journal of medicine.

[9]  R. Detrano,et al.  Quantification of coronary artery calcium using ultrafast computed tomography. , 1990, Journal of the American College of Cardiology.

[10]  Konstantin Nikolaou,et al.  Accuracy of 64-slice computed tomography to classify and quantify plaque volumes in the proximal coronary system: a comparative study using intravascular ultrasound. , 2006, Journal of the American College of Cardiology.

[11]  Maximilian Reiser,et al.  Composition of coronary atherosclerotic plaques in patients with acute myocardial infarction and stable angina pectoris determined by contrast-enhanced multislice computed tomography. , 2003, The American journal of cardiology.

[12]  J. Mehta,et al.  Evaluation of Venous and Arterial Conduit Patency by 16-Slice Spiral Computed Tomography , 2004, Circulation.

[13]  Udo Hoffmann,et al.  Predictive Value of 16-Slice Multidetector Spiral Computed Tomography to Detect Significant Obstructive Coronary Artery Disease in Patients at High Risk for Coronary Artery Disease: Patient- Versus Segment-Based Analysis , 2004, Circulation.

[14]  Heshui Shi,et al.  Noninvasive Coronary Angiography With Multislice Computed Tomography , 2005 .

[15]  W. B. Meijboom,et al.  Multislice Spiral Computed Tomography for the Evaluation of Stent Patency After Left Main Coronary Artery Stenting: A Comparison With Conventional Coronary Angiography and Intravascular Ultrasound , 2006, Circulation.

[16]  Konstantin Nikolaou,et al.  Accuracy of 64-MDCT in the diagnosis of ischemic heart disease. , 2006, AJR. American journal of roentgenology.

[17]  Konstantin Nikolaou,et al.  Accuracy of multidetector spiral computed tomography in identifying and differentiating the composition of coronary atherosclerotic plaques: a comparative study with intracoronary ultrasound. , 2004, Journal of the American College of Cardiology.

[18]  N. Matsumoto,et al.  Evaluation of plaque texture by means of multislice computed tomography in patients with acute coronary syndrome and stable angina. , 2004, Circulation journal : official journal of the Japanese Circulation Society.

[19]  Manesh R. Patel,et al.  ACCF/ACR/SCCT/SCMR/ASNC/NASCI/SCAI/SIR 2006 appropriateness criteria for cardiac computed tomography and cardiac magnetic resonance imaging. A report of the American College of Cardiology Foundation Quality Strategic Directions Committee Appropriateness Criteria Working Group. , 2006, Journal of the American College of Radiology : JACR.

[20]  Matthijs Oudkerk,et al.  Coronary angiography with multi-slice computed tomography , 2001, The Lancet.

[21]  Jeroen J. Bax,et al.  Feasibility of assessment of coronary stent patency using 16-slice computed tomography. , 2004, The American journal of cardiology.

[22]  W. Bautz,et al.  Assessment of coronary artery stent restenosis by 64-slice multi-detector computed tomography. , 2006, European heart journal.

[23]  M. Graif,et al.  Clinical value of 16‐slice multi‐detector CT compared to invasive coronary angiography , 2005, International journal of cardiovascular interventions.

[24]  C. Claussen,et al.  Image quality and diagnostic accuracy of non-invasive coronary imaging with 16 detector slice spiral computed tomography with 188 ms temporal resolution , 2005, Heart.

[25]  L. O. Yaneza,et al.  Non-invasive detection of significant coronary artery disease with multi-section computed tomography angiography in patients with suspected coronary artery disease. , 2006, Clinical radiology.

[26]  C Georg,et al.  Noninvasive detection and evaluation of atherosclerotic coronary plaques with multislice computed tomography. , 2001, Journal of the American College of Cardiology.

[27]  Rainer Raupach,et al.  64-slice multidetector coronary CT angiography: in vitro evaluation of 68 different stents , 2006, European Radiology.

[28]  S. Schroeder,et al.  Noninvasive detection of coronary lesions using 16-detector multislice spiral computed tomography technology , 2004 .

[29]  S. Achenbach,et al.  Comparison of measurement of cross-sectional coronary atherosclerotic plaque and vessel areas by 16-slice multidetector computed tomography versus intravascular ultrasound. , 2004, The American journal of cardiology.

[30]  Simon Wildermuth,et al.  Accuracy of MSCT coronary angiography with 64-slice technology: first experience. , 2005 .

[31]  W. B. Meijboom,et al.  Pre-operative computed tomography coronary angiography to detect significant coronary artery disease in patients referred for cardiac valve surgery. , 2006, Journal of the American College of Cardiology.

[32]  C. Claussen,et al.  Non-invasive evaluation of coronary artery bypass grafts using 16-row multi-slice computed tomography with 188 ms temporal resolution. , 2006, International journal of cardiology.

[33]  R. Romagnoli,et al.  Follow-up of coronary artery bypass graft patency by multislice computed tomography. , 2005, The American journal of cardiology.

[34]  Borut Marincek,et al.  Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control , 2006, European Radiology.

[35]  M. Hadamitzky,et al.  Improved noninvasive assessment of coronary artery bypass grafts with 64-slice computed tomographic angiography in an unselected patient population. , 2007, Journal of the American College of Cardiology.

[36]  Patrick W Serruys,et al.  Improved diagnostic accuracy with 16-row multi-slice computed tomography coronary angiography. , 2005, Journal of the American College of Cardiology.

[37]  Jeffrey J Fine,et al.  Comparison of accuracy of 64-slice cardiovascular computed tomography with coronary angiography in patients with suspected coronary artery disease. , 2006, The American journal of cardiology.

[38]  M F Reiser,et al.  Imaging of noncalcified coronary plaques using helical CT with retrospective ECG gating. , 2000, AJR. American journal of roentgenology.

[39]  M. Pfisterer,et al.  Limited diagnostic yield of non-invasive coronary angiography by 16-slice multi-detector spiral computed tomography in routine patients referred for evaluation of coronary artery disease. , 2005, European heart journal.

[40]  Filippo Cademartiri,et al.  Usefulness of multislice computed tomographic coronary angiography to assess in-stent restenosis. , 2005, The American journal of cardiology.

[41]  Konstantin Nikolaou,et al.  Ex vivo coronary atherosclerotic plaque characterization with multi-detector-row CT , 2003, European Radiology.

[42]  M. Bell,et al.  Intravenous electron-beam computed tomographic coronary angiography for segmental analysis of coronary artery stenoses. , 1998, Journal of the American College of Cardiology.

[43]  Konstantin Nikolaou,et al.  Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. , 2005, Journal of the American College of Cardiology.

[44]  C. Roobottom,et al.  Highly accurate coronary angiography with submillimetre, 16 slice computed tomography , 2005, Heart.

[45]  P. V. van Ooijen,et al.  Intravenous coronary angiography by electron beam computed tomography: a clinical evaluation. , 1998, Circulation.

[46]  Jonathan Lessick,et al.  Accuracy of 16-row multidetector computed tomography for the assessment of coronary artery stenosis. , 2006, JAMA.

[47]  Gilles Rioufol,et al.  Noninvasive assessment of left main coronary stent patency with 16-slice computed tomography. , 2005, The American journal of cardiology.

[48]  T. Fujii,et al.  Noninvasive assessment of coronary stents in patients by 16-slice computed tomography. , 2006, International journal of cardiology.

[49]  G. Raff,et al.  Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. , 2005, Journal of the American College of Cardiology.

[50]  Konstantin Nikolaou,et al.  Dual-source CT cardiac imaging: initial experience , 2006, European Radiology.

[51]  G. Simonetti,et al.  Accuracy of thin-slice computed tomography in the detection of coronary stenoses. , 2004, European heart journal.

[52]  Richard D. White,et al.  Non-invasive assessment of plaque morphology and remodeling in mildly stenotic coronary segments: comparison of 16-slice computed tomography and intravascular ultrasound , 2003, Coronary artery disease.

[53]  Filippo Cademartiri,et al.  Multislice spiral computed tomography coronary angiography in patients with stable angina pectoris. , 2004, Journal of the American College of Cardiology.

[54]  S. Achenbach,et al.  Detection of Calcified and Noncalcified Coronary Atherosclerotic Plaque by Contrast-Enhanced, Submillimeter Multidetector Spiral Computed Tomography: A Segment-Based Comparison With Intravascular Ultrasound , 2003, Circulation.

[55]  Eric Perrier,et al.  Comparison of coronary minimal lumen area quantification by sixty-four-slice computed tomography versus intravascular ultrasound for intermediate stenosis. , 2006, The American journal of cardiology.

[56]  K Bachmann,et al.  Coronary artery stenoses: three-dimensional imaging with electrocardiographically triggered, contrast agent-enhanced, electron-beam CT. , 1995, Radiology.

[57]  P. Carrascosa,et al.  Characterization of coronary atherosclerotic plaques by multidetector computed tomography. , 2006, The American journal of cardiology.

[58]  Pedro A. Lemos,et al.  Reliable Noninvasive Coronary Angiography With Fast Submillimeter Multislice Spiral Computed Tomography , 2002, Circulation.

[59]  Jeroen J. Bax,et al.  Prognostic value of multislice computed tomography coronary angiography in patients with known or suspected coronary artery disease. , 2007, Journal of the American College of Cardiology.

[60]  Jeroen J. Bax,et al.  Noninvasive coronary imaging and assessment of left ventricular function using 16-slice computed tomography. , 2005, The American journal of cardiology.

[61]  D. Oncel,et al.  Coronary stent patency and in-stent restenosis: determination with 64-section multidetector CT coronary angiography--initial experience. , 2007, Radiology.

[62]  C. Higgins,et al.  Coronary artery stenoses: assessment with contrast-enhanced electron-beam CT and axial reconstructions. , 1998, Radiology.

[63]  Udo Hoffmann,et al.  Assessment of coronary remodeling in stenotic and nonstenotic coronary atherosclerotic lesions by multidetector spiral computed tomography. , 2004, Journal of the American College of Cardiology.

[64]  William W O'Neill,et al.  A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain. , 2007, Journal of the American College of Cardiology.

[65]  W A Kalender,et al.  ECG-correlated image reconstruction from subsecond multi-slice spiral CT scans of the heart. , 2000, Medical physics.

[66]  Naoki Suzuki,et al.  Real-Time Volumetric Imaging of Human Heart Without Electrocardiographic Gating by 256-Detector Row Computed Tomography: Initial Experience , 2005, Journal of computer assisted tomography.

[67]  Peter Hunold,et al.  Noninvasive visualization of coronary artery bypass grafts using 16-detector row computed tomography. , 2004, Journal of the American College of Cardiology.

[68]  Patrik Rogalla,et al.  Noninvasive Detection of Coronary Artery Stenoses with Multislice Computed Tomography or Magnetic Resonance Imaging , 2006, Annals of Internal Medicine.

[69]  W. Bautz,et al.  Detection of Coronary Artery Stenoses With Thin-Slice Multi-Detector Row Spiral Computed Tomography and Multiplanar Reconstruction , 2003, Circulation.

[70]  W. Kalender,et al.  Contrast-enhanced coronary artery visualization by dual-source computed tomography--initial experience. , 2006, European journal of radiology.

[71]  C. Caussin,et al.  Characterization of vulnerable nonstenotic plaque with 16-slice computed tomography compared with intravascular ultrasound. , 2004, The American journal of cardiology.

[72]  R. Günther,et al.  64-slice computed tomography assessment of coronary artery stents: a phantom study , 2006, Acta radiologica.

[73]  D. Bluemke,et al.  Non-invasive half millimetre 32 detector row computed tomography angiography accurately excludes significant stenoses in patients with advanced coronary artery disease and high calcium scores , 2005, Heart.

[74]  P. Hall,et al.  Noninvasive coronary angiography: agreement of multi-slice spiral computed tomography and selective catheter angiography , 2004, The International Journal of Cardiovascular Imaging.

[75]  K. Stierstorfer,et al.  First performance evaluation of a dual-source CT (DSCT) system , 2006, European Radiology.

[76]  Werner Moshage,et al.  Detection of Coronary Artery Stenoses by Contrast-Enhanced, Retrospectively Electrocardiographically-Gated, Multislice Spiral Computed Tomography , 2001, Circulation.

[77]  D. Groves,et al.  Coronary artery bypass graft imaging using ECG-gated multislice computed tomography: comparison with catheter angiography. , 2005, Clinical radiology.

[78]  Gabriel P. Krestin,et al.  High-Resolution Spiral Computed Tomography Coronary Angiography in Patients Referred for Diagnostic Conventional Coronary Angiography , 2005, Circulation.

[79]  Udo Hoffmann,et al.  Coronary Multidetector Computed Tomography in the Assessment of Patients With Acute Chest Pain , 2006 .

[80]  S. Achenbach,et al.  Detection of coronary artery stenoses using multi-detector CT with 16 x 0.75 collimation and 375 ms rotation. , 2005, European heart journal.

[81]  Jonathan G Goldin,et al.  Assessment of Coronary Artery Disease by Cardiac Computed Tomography: A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiolog , 2006, Circulation.

[82]  B. Lewis,et al.  Diagnosis of coronary in-stent restenosis with multidetector row spiral computed tomography. , 2005, Journal of the American College of Cardiology.

[83]  M. Budoff,et al.  Intravenous three-dimensional coronary angiography using contrast enhanced electron beam computed tomography. , 1999, The American journal of cardiology.

[84]  Udo Hoffmann,et al.  Characterization of non-calcified coronary atherosclerotic plaque by multi-detector row CT: comparison to IVUS. , 2007, Atherosclerosis.

[85]  M. Reiser,et al.  Cardiac imaging by means of electrocardiographically gated multisection spiral CT: initial experience. , 2000, Radiology.

[86]  A. Knez,et al.  Quantification of Obstructive and Nonobstructive Coronary Lesions of 64-Slice Computed Tomography , 2005 .

[87]  Peter M T Pattynama,et al.  Evaluation of patients after coronary artery bypass surgery: CT angiographic assessment of grafts and coronary arteries. , 2003, Radiology.

[88]  W. Bautz,et al.  Diagnostic Accuracy of Noninvasive Coronary Angiography in Patients After Bypass Surgery Using 64-Slice Spiral Computed Tomography With 330-ms Gantry Rotation , 2006, Circulation.

[89]  N. Suzuki,et al.  Volumetric coronary angiography using the 256-detector row computed tomography scanner: comparison in vivo and in vitro with porcine models , 2006, Acta radiologica.

[90]  Jeroen J. Bax,et al.  Comprehensive assessment of patients after coronary artery bypass grafting by 16-detector-row computed tomography. , 2005, American heart journal.