A three-dimensional co-culture model of the aortic valve using magnetic levitation.

[1]  J. Hamako,et al.  von Willebrand factor and von Willebrand disease. , 2016, [Rinsho ketsueki] The Japanese journal of clinical hematology.

[2]  Craig A Simmons,et al.  Hemodynamic and cellular response feedback in calcific aortic valve disease. , 2013, Circulation research.

[3]  M. Kolonin,et al.  Adipose tissue engineering in three-dimensional levitation tissue culture system based on magnetic nanoparticles. , 2013, Tissue engineering. Part C, Methods.

[4]  R. Raphael,et al.  Assembly of a three-dimensional multitype bronchiole coculture model using magnetic levitation. , 2013, Tissue engineering. Part C, Methods.

[5]  A. Gotlieb,et al.  The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops. , 2013, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[6]  C. Tung,et al.  Detection of hydroxyapatite in calcified cardiovascular tissues. , 2012, Atherosclerosis.

[7]  K. Masters,et al.  A time course investigation of the statin paradox among valvular interstitial cell phenotypes. , 2012, American journal of physiology. Heart and circulatory physiology.

[8]  K. Billiar,et al.  Investigating the role of substrate stiffness in the persistence of valvular interstitial cell activation. , 2012, Journal of biomedical materials research. Part A.

[9]  April M. Kloxin,et al.  Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus , 2012, PloS one.

[10]  N. Rajamannan.  Calcific aortic valve disease: cellular origins of valve calcification. , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[11]  Kevin Kit Parker,et al.  Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve , 2011, Proceedings of the National Academy of Sciences.

[12]  P. Ohtonen,et al.  Statin treatment and gene expression of anti-atherogenic factor C-type natriuretic peptide system in stenotic aortic valves. , 2011, The Journal of heart valve disease.

[13]  E. Aikawa,et al.  Progenitor Cells Confer Plasticity to Cardiac Valve Endothelium , 2011, Journal of cardiovascular translational research.

[14]  Gretchen J. Mahler,et al.  Inflammatory Regulation of Valvular Remodeling: The Good(?), the Bad, and the Ugly , 2011, International journal of inflammation.

[15]  K. Masters,et al.  Can valvular interstitial cells become true osteoblasts? A side-by-side comparison. , 2011, The Journal of heart valve disease.

[16]  M. Georgescu,et al.  Invasive glioblastoma cells acquire stemness and increased Akt activation. , 2010, Neoplasia.

[17]  James A Bankson,et al.  Three-dimensional tissue culture based on magnetic cell levitation. , 2010, Nature nanotechnology.

[18]  K. Teo,et al.  Effect of Lipid Lowering With Rosuvastatin on Progression of Aortic Stenosis: Results of the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) Trial , 2010, Circulation.

[19]  Michael S Sacks,et al.  Endothelial progenitor cells as a sole source for ex vivo seeding of tissue-engineered heart valves. , 2010, Tissue engineering. Part A.

[20]  Kristi S Anseth,et al.  Statins Block Calcific Nodule Formation of Valvular Interstitial Cells by Inhibiting α-Smooth Muscle Actin Expression , 2009, Arteriosclerosis, thrombosis, and vascular biology.

[21]  K. Masters,et al.  Efficacy of Simvastatin Treatment of Valvular Interstitial Cells Varies With the Extracellular Environment , 2009, Arteriosclerosis, thrombosis, and vascular biology.

[22]  Craig A Simmons,et al.  Techniques for isolating and purifying porcine aortic valve endothelial cells. , 2008, The Journal of heart valve disease.

[23]  J. Bischoff,et al.  Opposing actions of Notch1 and VEGF in post-natal cardiac valve endothelial cells. , 2008, Biochemical and biophysical research communications.

[24]  J. Chambers,et al.  Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. , 2008, The New England journal of medicine.

[25]  W. Arap,et al.  Bottom-Up Assembly of Hydrogels from Bacteriophage and Au Nanoparticles: The Effect of Cis- and Trans-Acting Factors , 2008, PloS one.

[26]  C. Simmons,et al.  Mechanobiology of the aortic heart valve. , 2008, The Journal of heart valve disease.

[27]  V. Joag,et al.  The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology. , 2007, The American journal of pathology.

[28]  A. Chester,et al.  Molecular and functional characteristics of heart-valve interstitial cells , 2007, Philosophical Transactions of the Royal Society B: Biological Sciences.

[29]  Robert M Nerem,et al.  Valvular endothelial cells and the mechanoregulation of valvular pathology , 2007, Philosophical Transactions of the Royal Society B: Biological Sciences.

[30]  K. Grande-Allen,et al.  The use of collagenase III for the isolation of porcine aortic valvular interstitial cells: rationale and optimization. , 2007, The Journal of heart valve disease.

[31]  J. Zamorano,et al.  Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis. , 2007, Journal of the American College of Cardiology.

[32]  M. Amrani,et al.  Role of Human Valve Interstitial Cells in Valve Calcification and Their Response to Atorvastatin , 2006, Circulation.

[33]  R. Hinton,et al.  Extracellular Matrix Remodeling and Organization in Developing and Diseased Aortic Valves , 2006, Circulation research.

[34]  Robert M Nerem,et al.  Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress. , 2006, Tissue engineering.

[35]  C. Lilley,et al.  A Hybrid Vector for Ligand-Directed Tumor Targeting and Molecular Imaging , 2006, Cell.

[36]  Stefan Jockenhoevel,et al.  A collagen-glycosaminoglycan co-culture model for heart valve tissue engineering applications. , 2006, Biomaterials.

[37]  L. Griffith,et al.  Capturing complex 3D tissue physiology in vitro , 2006, Nature Reviews Molecular Cell Biology.

[38]  Wadih Arap,et al.  Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Robert M. Nerem,et al.  Transcriptional Profiles of Valvular and Vascular Endothelial Cells Reveal Phenotypic Differences: Influence of Shear Stress , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[40]  Kristi S Anseth,et al.  Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules. , 2005, Matrix biology : journal of the International Society for Matrix Biology.

[41]  R. Prescott,et al.  A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis. , 2005, The New England journal of medicine.

[42]  Craig A. Simmons,et al.  Spatial Heterogeneity of Endothelial Phenotypes Correlates With Side-Specific Vulnerability to Calcification in Normal Porcine Aortic Valves , 2005, Circulation research.

[43]  M. Schemper,et al.  Statins but Not Angiotensin-Converting Enzyme Inhibitors Delay Progression of Aortic Stenosis , 2004, Circulation.

[44]  Frederick J Schoen,et al.  Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves. , 2004, The Journal of heart valve disease.

[45]  L. Leinwand,et al.  Valvular Myofibroblast Activation by Transforming Growth Factor-&bgr;: Implications for Pathological Extracellular Matrix Remodeling in Heart Valve Disease , 2004, Circulation research.

[46]  Robert M Nerem,et al.  Unique Morphology and Focal Adhesion Development of Valvular Endothelial Cells in Static and Fluid Flow Environments , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[47]  Shuguang Zhang,et al.  Beyond the Petri dish , 2004, Nature Biotechnology.

[48]  A. Abbott.  Cell culture: Biology's new dimension , 2003, Nature.

[49]  Gino Gerosa,et al.  Cell characterization of porcine aortic valve and decellularized leaflets repopulated with aortic valve interstitial cells: the VESALIO Project (Vitalitate Exornatum Succedaneum Aorticum Labore Ingenioso Obtenibitur). , 2003, The Annals of thoracic surgery.

[50]  Magdi H. Yacoub,et al.  The cardiac valve interstitial cell. , 2003, The international journal of biochemistry & cell biology.

[51]  R. Levy,et al.  Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis. , 2003, The Annals of thoracic surgery.

[52]  E. Picano,et al.  Aortic valve sclerosis is associated with systemic endothelial dysfunction. , 2003, Journal of the American College of Cardiology.

[53]  L. Krishnan,et al.  A stable matrix for generation of tissue-engineered nonthrombogenic vascular grafts. , 2002, Tissue engineering.

[54]  F. Schoen,et al.  Aortic Valve Endothelial Cells Undergo Transforming Growth Factor-β-Mediated and Non-Transforming Growth Factor-β-Mediated Transdifferentiation in Vitro , 2001 .

[55]  F. Schoen,et al.  Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro. , 2001, The American journal of pathology.

[56]  D Guidolin,et al.  Cell composition of the human pulmonary valve: a comparative study with the aortic valve--the VESALIO Project. Vitalitate Exornatum Succedaneum Aorticum labore Ingegnoso Obtinebitur. , 2000, The Annals of thoracic surgery.

[57]  K. Müller,et al.  Expression of endothelial cell adhesion molecules on heart valves: up‐regulation in degeneration as well as acute endocarditis , 2000, The Journal of pathology.

[58]  J. Thyberg,et al.  Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[59]  T. Michel,et al.  Expression and regulation of endothelial nitric oxide synthase. , 1997, Trends in cardiovascular medicine.

[60]  A. Gotlieb,et al.  Cell biology of valvular interstitial cells. , 1996, The Canadian journal of cardiology.

[61]  M. Rosenqvist,et al.  Expression of HLA-DR antigen and smooth muscle cell differentiation markers by valvular fibroblasts in degenerative aortic stenosis. , 1994, Journal of the American College of Cardiology.

[62]  M. Rosenqvist,et al.  Accumulation of T lymphocytes and expression of interleukin-2 receptors in nonrheumatic stenotic aortic valves. , 1994, Journal of the American College of Cardiology.

[63]  G. Rubanyi.  Endothelium‐derived relaxing and contracting factors , 1991, Journal of cellular biochemistry.

[64]  V. Fuster,et al.  Platelet thrombus formation on collagen type I. A model of deep vessel injury. Influence of blood rheology, von Willebrand factor, and blood coagulation. , 1988, Circulation.

[65]  J D Hellums,et al.  Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin. , 1988, Blood.

[66]  J. Moake,et al.  Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation. , 1986, The Journal of clinical investigation.

[67]  J. Sixma,et al.  Subendothelial Proteins and Platelet Adhesion: von Willebrand Factor and Fibronectin, Not Thrombospondin, Are involved in Platelet Adhesion to Extracellular Matrix of Human Vascular Endothelial Cells , 1986, Arteriosclerosis.