The Link Between Adipose Tissue Renin-Angiotensin-Aldosterone System Signaling and Obesity-Associated Hypertension.
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[1] H. Lithell,et al. Alterations in skeletal muscle morphology in glucose‐tolerant elderly hypertensive men: relationship to development of hypertension and heart rate , 2000, Journal of hypertension.
[2] G. Adler,et al. Mineralocorticoid Receptor Blockade Reverses Obesity-Related Changes in Expression of Adiponectin, Peroxisome Proliferator-Activated Receptor-&ggr;, and Proinflammatory Adipokines , 2008, Circulation.
[3] Azra Mahmud,et al. Review: Arterial stiffness and the renin-angiotensin-aldosterone system , 2004 .
[4] T. Saruta,et al. Electrophysiological Properties of Rostral Ventrolateral Medulla Neurons in Angiotensin II 1a Receptor Knockout Mice , 2005, Hypertension.
[5] R. M. Lee,et al. Mechanisms for perivascular adipose tissue-mediated potentiation of vascular contraction to perivascular neuronal stimulation: the role of adipocyte-derived angiotensin II. , 2010, European journal of pharmacology.
[6] M. Mendelsohn,et al. Angiotensin II and Aldosterone Regulate Gene Transcription Via Functional Mineralocortocoid Receptors in Human Coronary Artery Smooth Muscle Cells , 2005, Circulation research.
[7] R. Schmieder,et al. Aldosterone-induced cardiac damage: focus on blood pressure independent effects. , 2003, American journal of hypertension.
[8] E. Schiffrin,et al. Angiotensin-(1-7) Through Receptor Mas Mediates Endothelial Nitric Oxide Synthase Activation via Akt-Dependent Pathways , 2007, Hypertension.
[9] V. V. van Hinsbergh,et al. Insulin-induced changes in skeletal muscle microvascular perfusion are dependent upon perivascular adipose tissue in women , 2015, Diabetologia.
[10] I. Reid. Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure. , 1992, The American journal of physiology.
[11] A. Ferreira,et al. Angiotensin-converting enzyme 2, angiotensin-(1-7) and Mas: new players of the renin-angiotensin system. , 2013, The Journal of endocrinology.
[12] C. Caruso-Neves,et al. The angiotensin receptor type 1–Gq protein–phosphatidyl inositol phospholipase Cβ–protein kinase C pathway is involved in activation of proximal tubule Na+‐ATPase activity by angiotensin(1–7) in pig kidneys , 2008, Experimental physiology.
[13] J. Loscalzo,et al. Aldosterone Inactivates the Endothelin-B Receptor via a Cysteinyl Thiol Redox Switch to Decrease Pulmonary Endothelial Nitric Oxide Levels and Modulate Pulmonary Arterial Hypertension , 2012, Circulation.
[14] R. Santos,et al. Brain-Selective Overexpression of Human Angiotensin-Converting Enzyme Type 2 Attenuates Neurogenic Hypertension , 2010, Circulation research.
[15] K. Sunagawa,et al. Sympathoinhibitory effects of telmisartan through the reduction of oxidative stress in the rostral ventrolateral medulla of obesity-induced hypertensive rats , 2012, Journal of hypertension.
[16] J. van de Voorde,et al. Adipose Tissue as Regulator of Vascular Tone , 2012, Current Hypertension Reports.
[17] J. Stern,et al. Compromised blood–brain barrier permeability: novel mechanism by which circulating angiotensin II signals to sympathoexcitatory centres during hypertension , 2016, The Journal of physiology.
[18] V. Demarco,et al. Vascular stiffness in insulin resistance and obesity , 2015, Front. Physiol..
[19] R. Widdop,et al. Angiotensin-(1–7) Acts as a Vasodepressor Agent Via Angiotensin II Type 2 Receptors in Conscious Rats , 2005, Hypertension.
[20] R. Schmieder,et al. Rapid Nongenomic Effects of Aldosterone on the Renal Vasculature in Humans , 2006, Hypertension.
[21] J. Sowers,et al. NADPH Oxidase Contributes to Vascular Inflammation, Insulin Resistance, and Remodeling in the Transgenic (mRen2) Rat , 2007, Hypertension.
[22] N. Naing,et al. The effects of angiotensin II on pulse wave velocity in healthy humans. , 2009, International journal of clinical pharmacology and therapeutics.
[23] W. Kannel,et al. Incidence and precursors of hypertension in young adults: the Framingham Offspring Study. , 1987, Preventive medicine.
[24] R. Touyz,et al. Adipocytes Produce Aldosterone Through Calcineurin-Dependent Signaling Pathways: Implications in Diabetes Mellitus–Associated Obesity and Vascular Dysfunction , 2012, Hypertension.
[25] K. Sandberg,et al. Reduction of plasma aldosterone and arterial stiffness in obese pre- and stage1 hypertensive subjects after aerobic exercise , 2014, Journal of Human Hypertension.
[26] W. White,et al. Effects of the Selective Aldosterone Blocker Eplerenone Versus the Calcium Antagonist Amlodipine in Systolic Hypertension , 2003, Hypertension.
[27] G. Tangelder,et al. Renal microvascular actions of angiotensin II fragments. , 2002, American journal of physiology. Renal physiology.
[28] D. Webb,et al. Changes in the derived central pressure waveform and pulse pressure in response to angiotensin II and noradrenaline in man , 2001, The Journal of physiology.
[29] R. Evans,et al. Renal sympathetic activation from long-term low-dose angiotensin II infusion in rabbits , 2012, Journal of hypertension.
[30] A. Ferguson,et al. Circulating signals as critical regulators of autonomic state--central roles for the subfornical organ. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.
[31] T. Tagawa,et al. AT(1) receptors mediate excitatory inputs to rostral ventrolateral medulla pressor neurons from hypothalamus. , 1999, Hypertension.
[32] Michael E. Hall,et al. Catheter-based radiorefrequency renal denervation lowers blood pressure in obese hypertensive dogs. , 2014, American journal of hypertension.
[33] A. Pries,et al. Microcirculation in Hypertension: A New Target for Treatment? , 2001, Circulation.
[34] T. Hussain,et al. Renal Angiotensin II Type-2 Receptors Are Upregulated and Mediate the Candesartan-Induced Natriuresis/Diuresis in Obese Zucker Rats , 2005, Hypertension.
[35] M. Schambelan,et al. The tissue renin‐angiotensin system in rats with fructose‐ induced hypertension: overexpression of type 1 angiotensin II receptor in adipose tissue , 2000, Journal of hypertension.
[36] Yiling Fu,et al. Mineralocorticoid-Induced Sodium Appetite and Renal Salt Retention: Evidence for Common Signaling and Effector Mechanisms , 2014, Nephron Physiology.
[37] K. Rahmouni,et al. Prolonged treatment with angiotensin 1–7 improves endothelial function in diet-induced obesity , 2013, Journal of hypertension.
[38] J. Bains,et al. ACTIONS OF ANGIOTENSIN IN THE SUBFORNICAL ORGAN AND AREA POSTREMA: IMPLICATIONS FOR LONG TERM CONTROL OF AUTONOMIC OUTPUT , 1997, Clinical and experimental pharmacology & physiology.
[39] C. de Ciuceis,et al. Blockade of the renin–angiotensin system in small arteries and anticontractile function of perivascular adipose tissue , 2015, Journal of hypertension.
[40] K. Sunagawa,et al. Activation of mineralocorticoid receptors in the rostral ventrolateral medulla is involved in hypertensive mechanisms in stroke-prone spontaneously hypertensive rats , 2012, Hypertension Research.
[41] C. Stehouwer,et al. Impaired Microvascular Function in Obesity: Implications for Obesity-Associated Microangiopathy, Hypertension, and Insulin Resistance , 2004, Circulation.
[42] T. Hussain,et al. AT2 receptor non-peptide agonist C21 promotes natriuresis in obese Zucker rats , 2012, Hypertension Research.
[43] A. Heagerty,et al. Perivascular adipose tissue from human systemic and coronary vessels: the emergence of a new pharmacotherapeutic target , 2012, British journal of pharmacology.
[44] A. A. da Silva,et al. Aldosterone Antagonism Attenuates Obesity-Induced Hypertension and Glomerular Hyperfiltration , 2004, Hypertension.
[45] A. Johnson,et al. Central endogenous angiotensin-(1-7) protects against aldosterone/NaCl-induced hypertension in female rats. , 2013, American journal of physiology. Heart and circulatory physiology.
[46] J. Webster,et al. Angiotensin II. Adrenergic sympathetic constrictor action in humans. , 1995, Circulation.
[47] L. Rosivall,et al. Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors. , 2002, American journal of physiology. Renal physiology.
[48] D. Warnock,et al. Angiotensin II directly stimulates ENaC activity in the cortical collecting duct via AT(1) receptors. , 2002, Journal of the American Society of Nephrology : JASN.
[49] J. Menani,et al. Hindbrain mineralocorticoid mechanisms on sodium appetite. , 2013, American journal of physiology. Regulatory, integrative and comparative physiology.
[50] Eric Vicaut,et al. Impaired Tissue Perfusion: A Pathology Common to Hypertension, Obesity, and Diabetes Mellitus , 2008, Circulation.
[51] R. Santos,et al. Angiotensin (1-7) Induces Mas Receptor Internalization , 2011, Hypertension.
[52] H. Struijker‐Boudier,et al. Current Perspectives on Arterial Stiffness and Pulse Pressure in Hypertension and Cardiovascular Diseases , 2003, Circulation.
[53] P. Dagnelie,et al. Age, waist circumference, and blood pressure are associated with skin microvascular flow motion: The Maastricht Study , 2014, Journal of hypertension.
[54] E. Schiffrin,et al. Angiotensin-(1-7) Counterregulates Angiotensin II Signaling in Human Endothelial Cells , 2007, Hypertension.
[55] Arya M. Sharma,et al. The adipose-tissue renin-angiotensin-aldosterone system: role in the metabolic syndrome? , 2003, The international journal of biochemistry & cell biology.
[56] R. Kreutz,et al. Comparative expression analysis of the renin-angiotensin system components between white and brown perivascular adipose tissue. , 2008, The Journal of endocrinology.
[57] J. T. ter Maaten,et al. Impaired Skin Capillary Recruitment in Essential Hypertension Is Caused by Both Functional and Structural Capillary Rarefaction , 2001, Hypertension.
[58] G. Sesti,et al. Angiotensin II Impairs the Insulin Signaling Pathway Promoting Production of Nitric Oxide by Inducing Phosphorylation of Insulin Receptor Substrate-1 on Ser312 and Ser616 in Human Umbilical Vein Endothelial Cells , 2004, Circulation research.
[59] N. Toda,et al. Aldosterone affects blood flow and vascular tone regulated by endothelium‐derived NO: therapeutic implications , 2013, British journal of pharmacology.
[60] Meredith J. Luttrell,et al. Mineralocorticoid receptors modulate vascular endothelial function in human obesity. , 2013, Clinical science.
[61] C. Acampora,et al. Effects of Losartan and Chlorthalidone on Blood Pressure and Renal Vascular Resistance Index in Non-Diabetic Patients with Essential Hypertension and Normal Renal Function , 2004, Journal of cardiovascular pharmacology.
[62] K. Nakao,et al. Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy. , 2010, American journal of hypertension.
[63] J. Yudkin,et al. Insulin's microvascular vasodilatory effects are inversely related to peripheral vascular resistance in overweight, but insulin‐sensitive subjects , 2013, Obesity.
[64] C. Stehouwer,et al. Visceral and truncal subcutaneous adipose tissue are associated with impaired capillary recruitment in healthy individuals. , 2006, The Journal of clinical endocrinology and metabolism.
[65] O. Krizanova,et al. Rat epididymal fat tissue express all components of the renin-angiotensin system. , 2000, General physiology and biophysics.
[66] J. Frisbee. Hypertension‐Independent Microvascular Rarefaction in the Obese Zucker Rat Model of the Metabolic Syndrome , 2005, Microcirculation.
[67] C. Caruso-Neves,et al. Angiotensin-(1–7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na+-ATPase activity via a A779-sensitve receptor , 2002, Regulatory Peptides.
[68] K. Griendling,et al. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. , 2007, American journal of physiology. Cell physiology.
[69] C. Gomez-Sanchez,et al. Intracerebroventricular infusion of RU28318 blocks aldosterone-salt hypertension. , 1990, The American journal of physiology.
[70] A. Heagerty,et al. Mechanisms of adiponectin-associated perivascular function in vascular disease. , 2014, Arteriosclerosis, thrombosis, and vascular biology.
[71] J. T. ter Maaten,et al. Microvascular function relates to insulin sensitivity and blood pressure in normal subjects. , 1999, Circulation.
[72] J. Fitzsimons,et al. The association of thirst, sodium appetite and vasopressin release with c-fos expression in the forebrain of the rat after intracerebroventricular injection of angiotensin II, angiotensin-(1–7) or carbachol , 1995, Neuroscience.
[73] A. Kroon,et al. Aldosterone-Renin Ratio and Side-Selective Renal Perfusion in Essential Hypertension. , 2016, American journal of hypertension.
[74] J. Twisk,et al. Body mass index is related to microvascular vasomotion, this is partly explained by adiponectin , 2014, European journal of clinical investigation.
[75] D. Randall,et al. Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension. , 2004, American journal of physiology. Regulatory, integrative and comparative physiology.
[76] B. Viollet,et al. Perivascular Adipose Tissue Control of Insulin-Induced Vasoreactivity in Muscle Is Impaired in db/db Mice , 2013, Diabetes.
[77] S. Nedogoda,et al. Randomized Trial of Perindopril, Enalapril, Losartan and Telmisartan in Overweight or Obese Patients with Hypertension , 2013, Clinical Drug Investigation.
[78] Y-B Zhou,et al. Superoxide anions modulate the effects of angiotensin-(1–7) in the rostral ventrolateral medulla on cardiac sympathetic afferent reflex and sympathetic activity in rats , 2012, Neuroscience.
[79] Zhenqi Liu,et al. Angiotensin II Receptors Modulate Muscle Microvascular and Metabolic Responses to Insulin In Vivo , 2011, Diabetes.
[80] G. Adler,et al. Effect of mineralocorticoid receptor antagonist on insulin resistance and endothelial function in obese subjects , 2014, Diabetes, obesity & metabolism.
[81] B. Del-Río-Navarro,et al. Effect of Losartan on Vascular Function in Fructose-Fed Rats: The Role of Perivascular Adipose Tissue , 2010, Clinical and experimental hypertension.
[82] S. Ko,et al. Hypertension Management and Microvascular Insulin Resistance in Diabetes , 2010, Current hypertension reports.
[83] K. Burns,et al. The role of angiotensin II-stimulated renal tubular transport in hypertension , 2003, Current hypertension reports.
[84] M. Phillips,et al. Levels of angiotensin and molecular biology of the tissue renin angiotensin systems , 1993, Regulatory Peptides.
[85] N. Vaziri,et al. Upregulation of Angiotensin II Type 1 Receptor, Inflammatory Mediators, and Enzymes of Arachidonate Metabolism in Obese Zucker Rat Kidney: Reversal by Angiotensin II Type 1 Receptor Blockade , 2005, Circulation.
[86] L. Cassis,et al. Characterization of renin activity in brown adipose tissue. , 1997, The American journal of physiology.
[87] G. Kajiyama,et al. Effects of Angiotensin-(1-7) on Forearm Circulation in Normotensive Subjects and Patients With Essential Hypertension , 2001, Hypertension.
[88] Jason D. Fowler,et al. Regulated renin release from 3T3-L1 adipocytes. , 2009, American journal of physiology. Endocrinology and metabolism.
[89] C. Stehouwer,et al. Microvascular Dysfunction: A Potential Mechanism in the Pathogenesis of Obesity‐associated Insulin Resistance and Hypertension , 2012, Microcirculation.
[90] J. Hall,et al. Angiotensin II and long-term arterial pressure regulation: the overriding dominance of the kidney. , 1999, Journal of the American Society of Nephrology : JASN.
[91] J. Paton,et al. Baroreflex inhibition of cardiac sympathetic outflow is attenuated by angiotensin II in the nucleus of the solitary tract , 2001, Neuroscience.
[92] S. Coppack,et al. Insulin-Mediated Upregulation of the Renin Angiotensin System in Human Subcutaneous Adipocytes Is Reduced by Rosiglitazone , 2005, Circulation.
[93] A. Heagerty,et al. Obesity-related hypertension: Epidemiology, pathophysiology, treatments, and the contribution of perivascular adipose tissue , 2012, Annals of medicine.
[94] N. Farman,et al. The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[95] W. Rascher,et al. Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release. , 1992, The Journal of pharmacology and experimental therapeutics.
[96] G. Schmid-Schönbein,et al. Enhancement of Glucocorticoid and Mineralocorticoid Receptor Density in the Microcirculation of the Spontaneously Hypertensive Rat , 2004, Microcirculation.
[97] C. Ecelbarger,et al. Aldosterone infusion with high-NaCl diet increases blood pressure in obese but not lean Zucker rats. , 2006, American journal of physiology. Renal physiology.
[98] C. Stehouwer,et al. Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity-associated insulin resistance and hypertension. , 2007, Physiology.
[99] M. Campagnole-Santos,et al. Differential baroreceptor reflex modulation by centrally infused angiotensin peptides. , 1992, The American journal of physiology.
[100] H. Tomita,et al. Aldosterone causes vasoconstriction in coronary arterioles of rats via angiotensin II type-1 receptor: influence of hypertension. , 2007, European journal of pharmacology.
[101] E. Barrett,et al. Angiotensin-(1–7) Recruits Muscle Microvasculature and Enhances Insulin’s Metabolic Action via Mas Receptor , 2014, Hypertension.
[102] J. Sowers,et al. Low-Dose Mineralocorticoid Receptor Blockade Prevents Western Diet–Induced Arterial Stiffening in Female Mice , 2015, Hypertension.
[103] Young Yang,et al. A novel adipokine CTRP1 stimulates aldosterone production , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[104] M. Raizada,et al. Overexpression of Angiotensin-Converting Enzyme 2 in the Rostral Ventrolateral Medulla Causes Long-Term Decrease in Blood Pressure in the Spontaneously Hypertensive Rats , 2007, Hypertension.
[105] T. Matsukawa,et al. Effects of intravenous infusions of angiotensin II on muscle sympathetic nerve activity in humans. , 1991, The American journal of physiology.
[106] G. Mancia,et al. Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: results of the CROSS study , 2003, Journal of hypertension.
[107] C. Stehouwer,et al. Physiological hyperinsulinaemia increases intramuscular microvascular reactive hyperaemia and vasomotion in healthy volunteers , 2004, Diabetologia.
[108] V. Achard,et al. Renin receptor expression in human adipose tissue. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.
[109] C. Ferrario,et al. Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[110] M. Brody,et al. Role of central mineralocorticoid binding sites in development of hypertension. , 1990, The American journal of physiology.
[111] S. Umemura,et al. Modulation of tissue angiotensinogen gene expression in genetically obese hypertensive rats. , 1997, The American journal of physiology.
[112] K. Sunagawa,et al. Angiotensin II receptor blockers improve endothelial dysfunction associated with sympathetic hyperactivity in metabolic syndrome , 2012, Journal of hypertension.
[113] Meredith J. Luttrell,et al. Acute effect of mineralocorticoid receptor antagonism on vascular function in healthy older adults , 2016, Experimental Gerontology.
[114] M. Emdin,et al. Microvascular responses to aldosterone in hamster cheek pouch microcirculation. , 2013, Clinical hemorheology and microcirculation.
[115] Reinder Evertz,et al. Direct evidence for insulin-induced capillary recruitment in skin of healthy subjects during physiological hyperinsulinemia. , 2002, Diabetes.
[116] K. Sutton-Tyrrell,et al. Serum Aldosterone Is Associated with Inflammation and Aortic Stiffness in Normotensive Overweight and Obese Young Adults , 2012, Clinical and experimental hypertension.
[117] Lina Zhao,et al. Losartan increases muscle insulin delivery and rescues insulin's metabolic action during lipid infusion via microvascular recruitment. , 2013, American journal of physiology. Endocrinology and metabolism.
[118] J. Hall,et al. Control of sodium excretion by angiotensin II: intrarenal mechanisms and blood pressure regulation. , 1986, The American journal of physiology.
[119] F. Ruschitzka,et al. Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity , 2013, European heart journal.
[120] De-Pei Li,et al. Angiotensin II Attenuates Synaptic GABA Release and Excites Paraventricular-Rostral Ventrolateral Medulla Output Neurons , 2005, Journal of Pharmacology and Experimental Therapeutics.
[121] Eric Lazartigues,et al. Angiotensin-Converting Enzyme 2 Overexpression in the Subfornical Organ Prevents the Angiotensin II–Mediated Pressor and Drinking Responses and Is Associated With Angiotensin II Type 1 Receptor Downregulation , 2008, Circulation research.
[122] R. Muniyappa,et al. Metabolic actions of angiotensin II and insulin: A microvascular endothelial balancing act , 2013, Molecular and Cellular Endocrinology.
[123] G. Sesti,et al. Angiotensin (1-7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs. , 2013, Cardiovascular research.
[124] D. Averill,et al. Losartan, nonpeptide angiotensin II-type 1 (AT1) receptor antagonist, attenuates pressor and sympathoexcitatory responses evoked by angiotensin II andL-glutamate in rostral ventrolateral medulla , 1994, Brain Research.
[125] P. D. de Leeuw,et al. Angiotensin II enhances insulin-stimulated whole-body glucose disposal but impairs insulin-induced capillary recruitment in healthy volunteers. , 2010, The Journal of clinical endocrinology and metabolism.
[126] A. Sugawara,et al. Nongenomic vascular action of aldosterone in the glomerular microcirculation. , 2003, Journal of the American Society of Nephrology : JASN.
[127] J. Blacher,et al. Association between increased plasma levels of aldosterone and decreased systemic arterial compliance in subjects with essential hypertension. , 1997, American journal of hypertension.
[128] A. Nishiyama,et al. Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats. , 2007, Journal of the American Society of Nephrology : JASN.
[129] J. Morrow,et al. Angiotensin receptor blockade improves arterial distensibility and reduces exercise-induced pressor responses in obese hypertensive patients with the metabolic syndrome. , 2004, American journal of hypertension.
[130] J. Sowers,et al. The pathophysiology of hypertension in patients with obesity , 2014, Nature Reviews Endocrinology.
[131] Z. Fortes,et al. Upregulation of ERK1/2-eNOS via AT2 Receptors Decreases the Contractile Response to Angiotensin II in Resistance Mesenteric Arteries from Obese Rats , 2014, PloS one.
[132] Yu-Ming Kang,et al. Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats. , 2008, American journal of physiology. Heart and circulatory physiology.
[133] Jia Liu,et al. Candesartan acutely recruits skeletal and cardiac muscle microvasculature in healthy humans. , 2012, The Journal of clinical endocrinology and metabolism.
[134] W. Spiering,et al. Mechanisms linking obesity to hypertension , 2012, Obesity reviews : an official journal of the International Association for the Study of Obesity.
[135] R. Iliescu,et al. Transgenic Angiotensin-Converting Enzyme 2 Overexpression in Vessels of SHRSP Rats Reduces Blood Pressure and Improves Endothelial Function , 2008, Hypertension.
[136] O. Carretero,et al. Vasodilator Action of Angiotensin-(1-7) on Isolated Rabbit Afferent Arterioles , 2002, Hypertension.
[137] L. Cassis,et al. Angiotensin Converting Enzyme 2 Contributes to Sex Differences in the Development of Obesity Hypertension in C57BL/6 Mice , 2012, Arteriosclerosis, thrombosis, and vascular biology.
[138] C. D. A. Stehouwer,et al. Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease , 2008, Diabetologia.
[139] J. Filosa,et al. Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis , 2015, Circulation.
[140] G. Giacchetti,et al. Overexpression of the renin-angiotensin system in human visceral adipose tissue in normal and overweight subjects. , 2002, American journal of hypertension.
[141] R. Klein,et al. Retinal vascular caliber and the development of hypertension: a meta-analysis of individual participant data , 2014, Journal of hypertension.
[142] David L. Brown,et al. Effect of inhibition of the renin-angiotensin system on development of type 2 diabetes mellitus (meta-analysis of randomized trials). , 2007, The American journal of cardiology.
[143] R. M. Lee,et al. Endothelium-dependent relaxation factor released by perivascular adipose tissue , 2009, Journal of hypertension.
[144] Daniel Levy,et al. Aortic stiffness, blood pressure progression, and incident hypertension. , 2012, JAMA.
[145] R. Kwong,et al. Mineralocorticoid Receptor Blockade Improves Coronary Microvascular Function in Individuals With Type 2 Diabetes , 2014, Diabetes.
[146] R. Charnigo,et al. Adipocyte Deficiency of Angiotensinogen Prevents Obesity-Induced Hypertension in Male Mice , 2012, Hypertension.
[147] A. Ferguson,et al. Subfornical organ neurons projecting to paraventricular nucleus: whole-cell properties , 2001, Brain Research.
[148] S. Laurent,et al. The structural factor of hypertension: large and small artery alterations. , 2015, Circulation research.
[149] Michael E. Hall,et al. Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms. , 2015, Circulation research.
[150] Hui Chen,et al. Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells* , 2003, Journal of Biological Chemistry.
[151] J. Loscalzo,et al. Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity , 2007, Nature Medicine.
[152] D. Lyn,et al. Eplerenone suppresses aldosterone/ salt-induced expression of NOX-4 , 2011, Journal of the renin-angiotensin-aldosterone system : JRAAS.
[153] E. Barrett,et al. Obesity Blunts Insulin-Mediated Microvascular Recruitment in Human Forearm Muscle , 2006, Diabetes.
[154] C. Caruso-Neves,et al. Involvement of the Gi/o/cGMP/PKG pathway in the AT2-mediated inhibition of outer cortex proximal tubule Na+-ATPase by Ang-(1-7). , 2006, The Biochemical journal.
[155] L. Sjöström,et al. Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II. , 1998, The Journal of clinical endocrinology and metabolism.
[156] B. Balkau,et al. Hypertension and vascular dynamics in men and women with metabolic syndrome. , 2013, Journal of the American College of Cardiology.
[157] E. Schiffrin,et al. Endothelin Antagonism on Aldosterone-Induced Oxidative Stress and Vascular Remodeling , 2003, Hypertension.
[158] B. Jensen,et al. Rapid actions of aldosterone in vascular health and disease--friend or foe? , 2006, Pharmacology & therapeutics.
[159] A. Loewy,et al. Aldosterone in the brain. , 2009, American journal of physiology. Renal physiology.
[160] D. Rizzoni,et al. Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients. , 2008, The Journal of clinical endocrinology and metabolism.
[161] M. G. Cogan,et al. Angiotensin II: a powerful controller of sodium transport in the early proximal tubule. , 1990, Hypertension.
[162] P. Challande,et al. Smooth Muscle Cell Mineralocorticoid Receptors Are Mandatory for Aldosterone–Salt to Induce Vascular Stiffness , 2014, Hypertension.
[163] Azra Mahmud,et al. Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. , 2005, American journal of hypertension.
[164] Leptin and aldosterone in sympathetic activity in resistant hypertension with or without type 2 diabetes. , 2012, Arquivos brasileiros de cardiologia.
[165] J. Loscalzo,et al. Aldosterone Increases Oxidant Stress to Impair Guanylyl Cyclase Activity by Cysteinyl Thiol Oxidation in Vascular Smooth Muscle Cells* , 2009, Journal of Biological Chemistry.
[166] D. Diz,et al. Pressor and reflex sensitivity is altered in spontaneously hypertensive rats treated with angiotensin-(1-7). , 1995, Hypertension.
[167] C Bogardus,et al. Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man. , 1987, The Journal of clinical investigation.
[168] F. Gao,et al. Vascular insulin resistance in prehypertensive rats: role of PI3-kinase/Akt/eNOS signaling. , 2010, European journal of pharmacology.
[169] M. Campagnole-Santos,et al. Evidence that angiotensin-(1–7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors , 1994, Brain Research.
[170] R. Britto,et al. Role of angiotensin-(1-7) in the modulation of the baroreflex in renovascular hypertensive rats. , 1997, Hypertension.
[171] E. Schiffrin,et al. Selective Mineralocorticoid Receptor Blocker Eplerenone Reduces Resistance Artery Stiffness in Hypertensive Patients , 2008, Hypertension.
[172] R. Santos,et al. Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone. , 2005, Hypertension.
[173] R. Carey,et al. Localization of angiotensin peptide-forming enzymes of 3T3-F442A adipocytes. , 1993, The American journal of physiology.
[174] M. Campagnole-Santos,et al. Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats. , 1996, Hypertension.
[175] I. Zucker,et al. Microinjection of ANG II into paraventricular nucleus enhances cardiac sympathetic afferent reflex in rats. , 2002, American journal of physiology. Heart and circulatory physiology.
[176] Arya M. Sharma,et al. Weight Loss and the Renin-Angiotensin-Aldosterone System , 2005, Hypertension.
[177] G. Giacchetti,et al. Comparison of circulating and local adipose tissue renin-angiotensin system in normotensive and hypertensive obese subjects , 2002, Journal of endocrinological investigation.
[178] L. Tallam,et al. Significance Of Exaggerated Natriuresis After Angiotensin AT1 Receptor Blockade Or Angiotensin‐ Converting Enzyme Inhibition In Obese Zucker Rats , 2001, Clinical and experimental pharmacology & physiology.
[179] H. Oberleithner,et al. The role of ENaC in vascular endothelium , 2013, Pflügers Archiv - European Journal of Physiology.
[180] F. Jessen,et al. Early-Onset and Late-Onset Depression Are Independent of the Genetic Polymorphism of Apolipoprotein E , 1999, Dementia and Geriatric Cognitive Disorders.
[181] J. T. ter Maaten,et al. Capillary recruitment is impaired in essential hypertension and relates to insulin's metabolic and vascular actions. , 2001, Cardiovascular research.
[182] N. Martell,et al. Characterization of angiotensin-(1-7) in the urine of normal and essential hypertensive subjects. , 1998, American journal of hypertension.
[183] A. Schreihofer,et al. Altered regulation of the rostral ventrolateral medulla in hypertensive obese Zucker rats. , 2011, American journal of physiology. Heart and circulatory physiology.
[184] Yen-Hung Lin,et al. Adrenalectomy improves increased carotid intima-media thickness and arterial stiffness in patients with aldosterone producing adenoma. , 2012, Atherosclerosis.
[185] S. Davidge,et al. Angiotensin-Converting Enzyme 2 Is a Critical Determinant of Angiotensin II–Induced Loss of Vascular Smooth Muscle Cells and Adverse Vascular Remodeling , 2014, Hypertension.
[186] K. Monahan,et al. Aldosterone impairs baroreflex sensitivity in healthy adults. , 2007, American journal of physiology. Heart and circulatory physiology.
[187] R. Iliescu,et al. Systemic and Renal‐Specific Sympathoinhibition in Obesity Hypertension , 2011, Hypertension.
[188] J. Maly,et al. Effect of Intrarenal Infusion of Angiotensin–(1–7) in the Dog , 2000, Kidney and Blood Pressure Research.
[189] J. Sowers,et al. Mineralocorticoid Receptor Antagonism Treats Obesity-Associated Cardiac Diastolic Dysfunction , 2015, Hypertension.
[190] I. Kowalik,et al. Postprocedural TIMI flow grade 2 in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary revascularization. (PL-ACS Registry) , 2013 .
[191] W. Mayhan,et al. Angiotensin-mediated increase in renal sympathetic nerve discharge within the PVN: role of nitric oxide. , 2001, American journal of physiology. Regulatory, integrative and comparative physiology.
[192] B. Adams-Huet,et al. Spironolactone Prevents Chlorthalidone-Induced Sympathetic Activation and Insulin Resistance in Hypertensive Patients , 2012, Hypertension.
[193] R. M. Lee,et al. Alterations in perivascular adipose tissue structure and function in hypertension. , 2011, European journal of pharmacology.
[194] M. Safar,et al. Increased Carotid Wall Elastic Modulus and Fibronectin in Aldosterone-Salt–Treated Rats: Effects of Eplerenone , 2002, Circulation.
[195] A. Nishiyama,et al. Aldosterone Suppresses Insulin Signaling Via the Downregulation of Insulin Receptor Substrate-1 in Vascular Smooth Muscle Cells , 2007, Hypertension.
[196] J. Francis,et al. ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension. , 2011, Cardiovascular research.
[197] P. D. de Leeuw,et al. Acute angiotensin II receptor blockade improves insulin-induced microvascular function in hypertensive individuals. , 2011, Microvascular research.
[198] C. Stehouwer,et al. Microvascular dysfunction as a link between obesity, insulin resistance and hypertension. , 2014, Diabetes research and clinical practice.
[199] K. Sunagawa,et al. Role of Angiotensin-(1-7) in Rostral Ventrolateral Medulla in Blood Pressure Regulation via Sympathetic Nerve Activity in Wistar-Kyoto and Spontaneous Hypertensive Rats , 2011, Clinical and experimental hypertension.
[200] Cynthia A. Reinhart-King,et al. Arterial Stiffening Precedes Systolic Hypertension in Diet-Induced Obesity , 2013, Hypertension.
[201] C. Kahn,et al. Cross-talk between the insulin and angiotensin signaling systems. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[202] R. Santos,et al. Systemic and regional hemodynamic effects of angiotensin-(1-7) in rats. , 2003, American journal of physiology. Heart and circulatory physiology.
[203] C. Gomez-Sanchez,et al. Central regulation of blood pressure by the mineralocorticoid receptor , 2012, Molecular and Cellular Endocrinology.
[204] M. Campagnole-Santos,et al. Central and peripheral actions of angiotensin-(1-7). , 1994, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
[205] R. Touyz,et al. Adipocytes, aldosterone and obesity-related hypertension. , 2016, Journal of molecular endocrinology.
[206] J. Filosa,et al. Circulating Angiotensin II Gains Access to the Hypothalamus and Brain Stem During Hypertension via Breakdown of the Blood–Brain Barrier , 2014, Hypertension.
[207] T. Yoshimoto,et al. Aldosterone induces superoxide generation via Rac1 activation in endothelial cells. , 2008, Endocrinology.
[208] A. Kroon,et al. Angiotensin-(1–7)–Induced Renal Vasodilation in Hypertensive Humans Is Attenuated by Low Sodium Intake and Angiotensin II Co-Infusion , 2013, Hypertension.
[209] M. Romero,et al. Modulation of phospholipase A2 activity and sodium transport by angiotensin-(1-7). , 1993, Kidney international.
[210] S. Umemura,et al. Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man. , 2000, Hypertension.
[211] I. Jaffe,et al. Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease , 2013, Pflügers Archiv - European Journal of Physiology.
[212] S. Millasseau,et al. Relations between large artery structure and function and aldosterone. , 2011, Journal of hypertension.
[213] A. Kroon,et al. Angiotensin-(1-7) as a strategy in the treatment of hypertension? , 2014, Current opinion in nephrology and hypertension.
[214] M. Campagnole-Santos,et al. Modulation of the baroreflex control of heart rate by angiotensin‐(1–7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats , 2000, Journal of hypertension.
[215] R. Henning,et al. The role of angiotensin(1–7) in renal vasculature of the rat , 2006, Journal of hypertension.
[216] G. Nguyen,et al. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. , 2002, The Journal of clinical investigation.
[217] J. Connell,et al. The new biology of aldosterone. , 2005, The Journal of endocrinology.
[218] P. Schling,et al. Human Adipose Tissue Cells Keep Tight Control on the Angiotensin II Levels in Their Vicinity* , 2002, The Journal of Biological Chemistry.
[219] J. Peti-Peterdi,et al. Angiotensin II stimulates macula densa basolateral sodium/hydrogen exchange via type 1 angiotensin II receptors. , 1999, Journal of the American Society of Nephrology : JASN.
[220] A. Stanton,et al. Pharmacological Modulation of Arterial Stiffness , 2011, Drugs.
[221] P. Schling,et al. Evidence for a local renin angiotensin system in primary cultured human preadipocytes , 1999, International Journal of Obesity.
[222] S. Engeli,et al. Co-expression of renin-angiotensin system genes in human adipose tissue. , 1999, Journal of hypertension.
[223] M. Safar,et al. Prevention of aortic fibrosis by spironolactone in spontaneously hypertensive rats. , 1997, Arteriosclerosis, thrombosis, and vascular biology.
[224] N. Martell,et al. Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension , 1996, Journal of hypertension.
[225] P. Arner,et al. Increased adipose angiotensinogen gene expression in human obesity. , 2000, Obesity research.
[226] J. Strandhoy,et al. Renal actions of angiotensin-(1-7): in vivo and in vitro studies. , 1996, The American journal of physiology.
[227] E. Barrett,et al. Skeletal muscle capillary responses to insulin are abnormal in late-stage diabetes and are restored by angiotensin-converting enzyme inhibition. , 2007, American journal of physiology. Endocrinology and metabolism.
[228] M. Barton,et al. Obesity and risk of vascular disease: importance of endothelium‐dependent vasoconstriction , 2012, British journal of pharmacology.
[229] A. Dupont,et al. Brain angiotensin peptides regulate sympathetic tone and blood pressure , 2010, Journal of hypertension.