Sudden Cardiac Death (SCD) – risk stratification and prediction with molecular biomarkers

[1]  M. Budoff,et al.  The prognostic value of interleukin 6 in multiple chronic diseases and all-cause death: The Multi-Ethnic Study of Atherosclerosis (MESA). , 2018, Atherosclerosis.

[2]  C. Fernández-Hernando,et al.  Endothelial Transcytosis of Lipoproteins in Atherosclerosis , 2018, Front. Cardiovasc. Med..

[3]  R. Jamal,et al.  Probing the colorectal cancer proteome for biomarkers: Current status and perspectives. , 2018, Journal of proteomics.

[4]  A. Barry,et al.  Long‐Term Beta‐Blocker Therapy after Myocardial Infarction in the Reperfusion Era: A Systematic Review , 2018, Pharmacotherapy.

[5]  R. Pontremoli,et al.  Hypertriglyceridemia and omega-3 fatty acids: Their often overlooked role in cardiovascular disease prevention. , 2017, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[6]  A. Quyyumi,et al.  Biomarkers to Predict Cardiovascular Death. , 2017, Cardiac electrophysiology clinics.

[7]  Bei Cheng,et al.  The clinical value of inflammatory biomarkers in coronary artery disease: PTX3 as a new inflammatory marker , 2017, Experimental Gerontology.

[8]  S. Chugh Sudden cardiac death in 2017: Spotlight on prediction and prevention. , 2017, International journal of cardiology.

[9]  J. Goldberger,et al.  Sudden Cardiac Arrest Risk Assessment: Population Science and the Individual Risk Mandate , 2017, JAMA cardiology.

[10]  J. Skinner,et al.  Utility of Post-Mortem Genetic Testing in Cases of Sudden Arrhythmic Death Syndrome , 2017, Journal of the American College of Cardiology.

[11]  S. Basu,et al.  Targeting LDL Cholesterol: Beyond Absolute Goals Toward Personalized Risk , 2017, Current Cardiology Reports.

[12]  J. Nerbonne,et al.  Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics , 2017, The Journal of physiology.

[13]  A. Quyyumi,et al.  Pathway-Specific Aggregate Biomarker Risk Score Is Associated With Burden of Coronary Artery Disease and Predicts Near-Term Risk of Myocardial Infarction and Death , 2017, Circulation. Cardiovascular quality and outcomes.

[14]  Xilin Wang,et al.  Association between interleukin-6 and the risk of cardiac events measured by coronary computed tomography angiography , 2017, The International Journal of Cardiovascular Imaging.

[15]  Juan Wang,et al.  Novel biomarkers for cardiovascular risk prediction , 2017, Journal of geriatric cardiology : JGC.

[16]  R. Stocker,et al.  The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture , 2016, Redox report : communications in free radical research.

[17]  D. Atar,et al.  Neurohormonal Blockade in Heart Failure. , 2016, Cardiac failure review.

[18]  D. Mann,et al.  Neurohormonal activation in heart failure with reduced ejection fraction , 2017, Nature Reviews Cardiology.

[19]  S. Yale,et al.  Erythrocyte Sedimentation Rate and C-reactive Protein Measurements and Their Relevance in Clinical Medicine. , 2016, WMJ : official publication of the State Medical Society of Wisconsin.

[20]  H. Arnesen,et al.  Combined Elevated Levels of the Proinflammatory Cytokines IL-18 and IL-12 Are Associated with Clinical Events in Patients with Coronary Artery Disease: An Observational Study. , 2016, Metabolic syndrome and related disorders.

[21]  P. Villablanca,et al.  Soluble urokinase plasminogen activation receptor - An emerging new biomarker of cardiovascular disease and critical illness , 2016, Annals of cardiac anaesthesia.

[22]  S. Cook,et al.  Development of a Comprehensive Sequencing Assay for Inherited Cardiac Condition Genes , 2016, Journal of Cardiovascular Translational Research.

[23]  A. Heck,et al.  Reconciling proteomics with next generation sequencing. , 2016, Current opinion in chemical biology.

[24]  Dean P. Jones,et al.  Novel Biomarker of Oxidative Stress Is Associated With Risk of Death in Patients With Coronary Artery Disease , 2016, Circulation.

[25]  S. Chugh,et al.  Population-Based Analysis of Sudden Cardiac Death With and Without Left Ventricular Systolic Dysfunction , 2016 .

[26]  J. Makielski,et al.  Identification of rare variants of DSP gene in sudden unexplained nocturnal death syndrome in the southern Chinese Han population , 2016, International Journal of Legal Medicine.

[27]  K. Reinier,et al.  Electrocardiographic Markers and the Left Ventricular Ejection Fraction have Cumulative Effects on Risk of Sudden Cardiac Death. , 2015, JACC. Clinical electrophysiology.

[28]  J. Jeppesen,et al.  suPAR: A New Biomarker for Cardiovascular Disease? , 2015, The Canadian journal of cardiology.

[29]  A. Sheikh,et al.  Early repolarization syndrome: A cause of sudden cardiac death. , 2015, World journal of cardiology.

[30]  Deepak L. Bhatt,et al.  Troponin and Cardiac Events in Stable Ischemic Heart Disease and Diabetes. , 2015, The New England journal of medicine.

[31]  K. Törő,et al.  A Common Polymorphism of the Human Cardiac Sodium Channel Alpha Subunit (SCN5A) Gene Is Associated with Sudden Cardiac Death in Chronic Ischemic Heart Disease , 2015, PloS one.

[32]  Y. Aizawa,et al.  Cardiac innervation and sudden cardiac death. , 2015, Circulation research.

[33]  A. Angelini,et al.  A founder MYBPC3 mutation results in HCM with a high risk of sudden death after the fourth decade of life , 2015, Journal of Medical Genetics.

[34]  X. Jouven,et al.  Microparticles and sudden cardiac death due to coronary occlusion. The TIDE (Thrombus and Inflammation in sudden DEath) study , 2015, European heart journal. Acute cardiovascular care.

[35]  K. Mahajan Interleukin-18 and Atherosclerosis: Mediator or Biomarker , 2014 .

[36]  Kathleen F. Kerr,et al.  A Common SCN5A Variant Is Associated with PR Interval and Atrial Fibrillation Among African Americans , 2014, Journal of cardiovascular electrophysiology.

[37]  W. Peacock Novel biomarkers in acute heart failure: MR-pro-adrenomedullin , 2014, Clinical chemistry and laboratory medicine.

[38]  A. Quyyumi,et al.  The Evaluation of Novel Biomarkers and the Multiple Biomarker Approach in the Prediction of Cardiovascular Disease , 2014, Current Cardiovascular Risk Reports.

[39]  F. Gustafsson,et al.  Copeptin as a biomarker in heart failure. , 2014, Biomarkers in medicine.

[40]  Nicole Schmitt,et al.  Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia. , 2014, Physiological reviews.

[41]  M. de Antonio,et al.  Head-to-head comparison of 2 myocardial fibrosis biomarkers for long-term heart failure risk stratification: ST2 versus galectin-3. , 2014, Journal of the American College of Cardiology.

[42]  T. Hansen,et al.  Cardiovascular risk prediction in the general population with use of suPAR, CRP, and Framingham Risk Score. , 2013, International journal of cardiology.

[43]  Dan M Roden,et al.  Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death , 2013, Nature Genetics.

[44]  V. Salomaa,et al.  Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population , 2013, Annals of medicine.

[45]  A. Sinha Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D). , 2013 .

[46]  C. Carnes,et al.  'Ryanopathy': causes and manifestations of RyR2 dysfunction in heart failure. , 2013, Cardiovascular research.

[47]  M. Cleman,et al.  Asymmetric Dimethylarginine (ADMA): a promising biomarker for cardiovascular disease? , 2013, Current topics in medicinal chemistry.

[48]  J. Svendsen,et al.  The Prevalence of Mutations in KCNQ1, KCNH2, and SCN5A in an Unselected National Cohort of Young Sudden Unexplained Death Cases , 2012, Journal of cardiovascular electrophysiology.

[49]  L. Tavazzi,et al.  Pentraxin‐3 in chronic heart failure: the CORONA and GISSI‐HF trials , 2012, European journal of heart failure.

[50]  V. Salomaa,et al.  Common Genetic Variants Associated with Sudden Cardiac Death: The FinSCDgen Study , 2012, PloS one.

[51]  D. Tester,et al.  Cardiac channel molecular autopsy: insights from 173 consecutive cases of autopsy-negative sudden unexplained death referred for postmortem genetic testing. , 2012, Mayo Clinic proceedings.

[52]  H. Harn,et al.  Angiotensin converting enzyme DD genotype is associated with acute coronary syndrome severity and sudden cardiac death in Taiwan: a case-control emergency room study , 2012, BMC Cardiovascular Disorders.

[53]  S. Chugh,et al.  Plasma Biomarkers for Prediction of Sudden Cardiac Death: Another Piece of the Risk Stratification Puzzle? , 2012, Circulation. Arrhythmia and electrophysiology.

[54]  C. Albert,et al.  Epidemiology and genetics of sudden cardiac death. , 2012, Circulation.

[55]  L. Tavazzi,et al.  Serial Measurement of Cardiac Troponin T Using a Highly Sensitive Assay in Patients With Chronic Heart Failure: Data From 2 Large Randomized Clinical Trials , 2012, Circulation.

[56]  M. Volpe,et al.  Plasma osteopontin reveals left ventricular reverse remodelling following cardiac resynchronization therapy in heart failure. , 2011, International journal of cardiology.

[57]  W. März,et al.  Associations of plasma renin with 10-year cardiovascular mortality, sudden cardiac death, and death due to heart failure. , 2011, European heart journal.

[58]  Sujoy Ghosh,et al.  Natriuretic peptides: Diagnostic and therapeutic use , 2011, Indian journal of endocrinology and metabolism.

[59]  P. Ponikowski,et al.  Increased 90-Day Mortality in Patients With Acute Heart Failure With Elevated Copeptin: Secondary Results From the Biomarkers in Acute Heart Failure (BACH) Study , 2011, Circulation. Heart failure.

[60]  R. Frye,et al.  Profibrinolytic, Antithrombotic, and Antiinflammatory Effects of an Insulin-Sensitizing Strategy in Patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial , 2011, Circulation.

[61]  A. Uy‐Evanado,et al.  Prolonged Tpeak-to-Tend Interval on the Resting ECG Is Associated With Increased Risk of Sudden Cardiac Death , 2011, Circulation. Arrhythmia and electrophysiology.

[62]  A. Hofman,et al.  Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals , 2011, PLoS genetics.

[63]  R. Kronmal,et al.  N-terminal pro-B-type natriuretic peptide is associated with sudden cardiac death risk: the Cardiovascular Health Study. , 2011, Heart rhythm.

[64]  A. Khera,et al.  Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. , 2010, JAMA.

[65]  K. Strimbu,et al.  What are biomarkers? , 2010, Current opinion in HIV and AIDS.

[66]  X. Jouven,et al.  C-Reactive Protein, Interleukin 6, Fibrinogen and Risk of Sudden Death in European Middle-Aged Men: The PRIME Study , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[67]  J. Manson,et al.  Common Variants in Cardiac Ion Channel Genes Are Associated With Sudden Cardiac Death , 2010, Circulation. Arrhythmia and electrophysiology.

[68]  P. Ponikowski,et al.  Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial. , 2010, Journal of the American College of Cardiology.

[69]  W. März,et al.  Plasma aldosterone levels are associated with increased cardiovascular mortality: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. , 2010, European heart journal.

[70]  B. Gersh,et al.  Sudden cardiac death: epidemiology and risk factors , 2010, Nature Reviews Cardiology.

[71]  M. Pfeffer,et al.  A sensitive cardiac troponin T assay in stable coronary artery disease. , 2009, The New England journal of medicine.

[72]  Dean P. Jones,et al.  Measuring the poise of thiol/disulfide couples in vivo. , 2009, Free radical biology & medicine.

[73]  R. Khalil,et al.  Inflammatory cytokines in vascular dysfunction and vascular disease. , 2009, Biochemical pharmacology.

[74]  B. Khan,et al.  Usefulness of elevations in serum choline and free F2)-isoprostane to predict 30-day cardiovascular outcomes in patients with acute coronary syndrome. , 2009, The American journal of cardiology.

[75]  N. Cook,et al.  Amino-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity C-Reactive Protein as Predictors of Sudden Cardiac Death Among Women , 2009, Circulation.

[76]  Linda Greensmith,et al.  Induction of heat shock proteins for protection against oxidative stress. , 2009, Advanced drug delivery reviews.

[77]  Dawn Peters,et al.  Determinants of Prolonged QT Interval and Their Contribution to Sudden Death Risk in Coronary Artery Disease: The Oregon Sudden Unexpected Death Study , 2009, Circulation.

[78]  P. Libby,et al.  Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. , 2008, The New England journal of medicine.

[79]  J. Struck,et al.  Comparison of copeptin, B-type natriuretic peptide, and amino-terminal pro-B-type natriuretic peptide in patients with chronic heart failure: prediction of death at different stages of the disease. , 2008, Journal of the American College of Cardiology.

[80]  R. Lavi,et al.  Role of lipoprotein-associated phospholipase A2 in atherosclerosis , 2008, Current atherosclerosis reports.

[81]  E. Barrett-Connor,et al.  Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo Study. , 2008, Journal of the American College of Cardiology.

[82]  M. Pencina,et al.  General Cardiovascular Risk Profile for Use in Primary Care: The Framingham Heart Study , 2008, Circulation.

[83]  Giuseppe Lippi,et al.  Sudden cardiac death: Prevalence, pathogenesis, and prevention , 2008, Annals of medicine.

[84]  J. Cohn,et al.  Prognostic Value of Very Low Plasma Concentrations of Troponin T in Patients With Stable Chronic Heart Failure , 2007, Circulation.

[85]  Palazzuoli Alberto,et al.  Acute Coronary Syndromes: From The Laboratory Markers To The Coronary Vessels , 2006, Biomarker insights.

[86]  G. Montalescot,et al.  High Plasma Aldosterone Levels on Admission Are Associated With Death in Patients Presenting With Acute ST-Elevation Myocardial Infarction , 2006, Circulation.

[87]  D. Mozaffarian,et al.  Plasma Phospholipid Trans Fatty Acids, Fatal Ischemic Heart Disease, and Sudden Cardiac Death in Older Adults: The Cardiovascular Health Study , 2006, Circulation.

[88]  Karen L. Gunson,et al.  Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction: two-year findings from the Oregon Sudden Unexpected Death Study. , 2006, Journal of the American College of Cardiology.

[89]  BjörnZethelius,et al.  Troponin I as a Predictor of Coronary Heart Disease and Mortality in 70-Year-Old Men , 2006 .

[90]  P. Venge,et al.  Troponin I as a Predictor of Coronary Heart Disease and Mortality in 70-Year-Old Men: A Community-Based Cohort Study , 2006, Circulation.

[91]  T. Thomsen HeartScore®: a new web-based approach to European cardiovascular disease risk management , 2005, European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology.

[92]  J. Struck,et al.  Measurement of midregional proadrenomedullin in plasma with an immunoluminometric assay. , 2005, Clinical chemistry.

[93]  K. Ley,et al.  Macrophage differentiation to foam cells. , 2005, Current pharmaceutical design.

[94]  A. Zalewski,et al.  Role of Lipoprotein-Associated Phospholipase A2 in Atherosclerosis: Biology, Epidemiology, and Possible Therapeutic Target , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[95]  J. Morrow,et al.  F2-Isoprostanes as markers of oxidative stress in vivo: An overview , 2005, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

[96]  C. Garlanda,et al.  Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. , 2005, Annual review of immunology.

[97]  J. Keaney,et al.  Hypochlorous Acid Impairs Endothelium-Derived Nitric Oxide Bioactivity Through a Superoxide-Dependent Mechanism , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[98]  C. Meisinger,et al.  Lipoprotein-Associated Phospholipase A2 Adds to Risk Prediction of Incident Coronary Events by C-Reactive Protein in Apparently Healthy Middle-Aged Men From the General Population: Results From the 14-Year Follow-Up of a Large Cohort From Southern Germany , 2004, Circulation.

[99]  J. McMurray,et al.  Anemia and Its Relationship to Clinical Outcome in Heart Failure , 2004, Circulation.

[100]  G. Lamas,et al.  Prolonged QTc interval and risks of total and cardiovascular mortality and sudden death in the general population: a review and qualitative overview of the prospective cohort studies. , 2004, Archives of internal medicine.

[101]  Uichi Ikeda,et al.  Matrix metalloproteinases and atherosclerosis , 2004, Current atherosclerosis reports.

[102]  C. Meisinger,et al.  Lipoprotein-Associated Phospholipase A 2 Adds to Risk Prediction of Incident Coronary Events by C-Reactive Protein in Apparently Healthy Middle-Aged Men From the General Population , 2004 .

[103]  A. Quyyumi,et al.  Increased Serum Levels of Heat Shock Protein 70 Are Associated With Low Risk of Coronary Artery Disease , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[104]  Paul M. Ridker,et al.  Prospective Study of C-Reactive Protein, Homocysteine, and Plasma Lipid Levels as Predictors of Sudden Cardiac Death , 2002, Circulation.

[105]  R. Berger,et al.  B-Type Natriuretic Peptide Predicts Sudden Death in Patients With Chronic Heart Failure , 2002, Circulation.

[106]  J. Cohn,et al.  A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. , 2001, The New England journal of medicine.

[107]  X. Jouven,et al.  Circulating Nonesterified Fatty Acid Level as a Predictive Risk Factor for Sudden Death in the Population , 2001, Circulation.

[108]  S. Coppack,et al.  C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[109]  T. Ueno,et al.  Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes. , 1998, Journal of the American College of Cardiology.

[110]  R. Rodeheffer,et al.  Cardiac secretion of adrenomedullin in human heart failure. , 1996, The Journal of clinical investigation.

[111]  T. Ishimitsu,et al.  Increased plasma levels of adrenomedullin in patients with heart failure. , 1995, Journal of the American College of Cardiology.