Constant hypoxia inhibits osteoclast differentiation and bone resorption by regulating phosphorylation of JNK and IκBα
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Jinxia Zhao | Xiangyuan Liu | Zhenzhen Ma | Lin Sun | Chang-hong Li | R. Yu | L. Jian
[1] A. Maurizi,et al. The Osteoclast in Bone Metastasis: Player and Target , 2018, Cancers.
[2] Yoshiya Tanaka,et al. Mechanisms and therapeutic targets for bone damage in rheumatoid arthritis, in particular the RANK‐RANKL system , 2018, Current opinion in pharmacology.
[3] X. Liu,et al. Hypoxia induces production of citrullinated proteins in human fibroblast‐like synoviocytes through regulating HIF1α , 2018, Scandinavian journal of immunology.
[4] A. Barton,et al. Rheumatoid arthritis , 2018, Nature Reviews Disease Primers.
[5] T. Nakashima,et al. Recent advances in osteoclast biology , 2018, Histochemistry and Cell Biology.
[6] J. Rho,et al. Regulation of Osteoclast Differentiation by Cytokine Networks , 2018, Immune network.
[7] Y. Soh,et al. Macrolactin F inhibits RANKL‐mediated osteoclastogenesis by suppressing Akt, MAPK and NFATc1 pathways and promotes osteoblastogenesis through a BMP‐2/smad/Akt/Runx2 signaling pathway , 2017, European journal of pharmacology.
[8] Soo Young Lee,et al. Current Understanding of RANK Signaling in Osteoclast Differentiation and Maturation , 2017, Molecules and cells.
[9] Jin Qi,et al. Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway , 2017, Front. Immunol..
[10] N. Lee,et al. Up-Regulation of RANK Expression via ERK1/2 by Insulin Contributes to the Enhancement of Osteoclast Differentiation , 2017, Molecules and cells.
[11] Liren Li,et al. Functional disability associated with disease and quality-of-life parameters in Chinese patients with rheumatoid arthritis , 2017, Health and Quality of Life Outcomes.
[12] H. Knowles,et al. Hypoxia‐inducible factor 1‐alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl‐4‐hydroxylase 2 , 2017, The Journal of pathology.
[13] Baojie Li,et al. p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner , 2017, Scientific Reports.
[14] D. Peng,et al. Gastrodin inhibits osteoclastogenesis via down-regulating the NFATc1 signaling pathway and stimulates osseointegration in vitro. , 2017, Biochemical and biophysical research communications.
[15] H. Yamanaka,et al. RANK Expression and Osteoclastogenesis in Human Monocytes in Peripheral Blood from Rheumatoid Arthritis Patients , 2016, BioMed research international.
[16] Mingli Yang,et al. Eriodictyol Inhibits RANKL‐Induced Osteoclast Formation and Function Via Inhibition of NFATc1 Activity , 2016, Journal of cellular physiology.
[17] S. González-Chávez,et al. Hypoxia and its implications in rheumatoid arthritis , 2016, Journal of Biomedical Science.
[18] V. Nevzorova,et al. Role of Osteoprotegerin and Receptor Activator of Nuclear Factor-κB Ligand in Bone Loss Related to Advanced Chronic Obstructive Pulmonary Disease , 2016, Chinese medical journal.
[19] D. Hao,et al. Natural products for treatment of bone erosive diseases: The effects and mechanisms on inhibiting osteoclastogenesis and bone resorption. , 2016, International immunopharmacology.
[20] Shuhua Yang,et al. Role of Epithelium Sodium Channel in Bone Formation , 2016, Chinese medical journal.
[21] H. Knowles. Hypoxic regulation of osteoclast differentiation and bone resorption activity , 2015, Hypoxia.
[22] E. Rankin,et al. Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin , 2015, Genes & development.
[23] L. Deng,et al. HIF-1α disturbs osteoblasts and osteoclasts coupling in bone remodeling by up-regulating OPG expression , 2015, In Vitro Cellular & Developmental Biology - Animal.
[24] Yongwon Choi,et al. Biology of the RANKL–RANK–OPG System in Immunity, Bone, and Beyond , 2014, Front. Immunol..
[25] M. Oyama,et al. Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell–cell fusion , 2012, The Journal of cell biology.
[26] W. Wilson,et al. Targeting hypoxia in cancer therapy , 2011, Nature Reviews Cancer.
[27] M. Zaiss,et al. Interleukin‐33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[28] M. Gillespie,et al. Interleukin-33, a target of parathyroid hormone and oncostatin m, increases osteoblastic matrix mineral deposition and inhibits osteoclast formation in vitro. , 2011, Endocrinology.
[29] A. Flanagan,et al. Hypoxia stimulates osteoclast formation from human peripheral blood , 2010, Cell biochemistry and function.
[30] Seng H. Cheng,et al. Inhibition of osteoclastogenesis by prolyl hydroxylase inhibitor dimethyloxallyl glycine , 2010, Journal of Bone and Mineral Metabolism.
[31] Zhangkun Li. [Facing the challenge of low recognition and high disability in rheumatoid arthritis]. , 2009, Zhonghua yi xue za zhi.
[32] H. Knowles,et al. Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis , 2009, The Journal of pathology.
[33] H. Lee,et al. Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice. , 2009, The Journal of clinical investigation.
[34] B. Wouters,et al. Hypoxia signalling through mTOR and the unfolded protein response in cancer , 2008, Nature Reviews Cancer.
[35] J. Price,et al. Hypoxia Induces Giant Osteoclast Formation and Extensive Bone Resorption in the Cat , 2006, Calcified Tissue International.
[36] Y. Nogi,et al. Essential Role of p38 Mitogen-activated Protein Kinase in Cathepsin K Gene Expression during Osteoclastogenesis through Association of NFATc1 and PU.1* , 2004, Journal of Biological Chemistry.
[37] T. Arnett,et al. Hypoxia is a major stimulator of osteoclast formation and bone resorption , 2003, Journal of cellular physiology.
[38] Hao Wu,et al. Distinct molecular mechanism for initiating TRAF6 signalling , 2002, Nature.
[39] D. Mccarty,et al. Synovial fluid pH, lactate, oxygen and carbon dioxide partial pressure in various joint diseases. , 1971, Arthritis and rheumatism.
[40] K Lund-Olesen,et al. Oxygen tension in synovial fluids. , 1970, Arthritis and rheumatism.
[41] H. Takayanagi,et al. Analysis of NFATc1-centered transcription factor regulatory networks in osteoclast formation. , 2014, Methods in molecular biology.
[42] C. P. Winlove,et al. Synovial hypoxia as a cause of tendon rupture in rheumatoid arthritis. , 2008, The Journal of hand surgery.
[43] C. Werning. [Rheumatoid arthritis]. , 1983, Medizinische Monatsschrift fur Pharmazeuten.