Estimates of the economic costs of birth defects.

Birth defects now are the leading cause of infant mortality and a major contributor to heightened morbidity in the United States. Considerable medical and nonmedical resources are devoted to treating persons with birth defects. Yet, little is known about birth defects' economic burden to society and the profile of component direct and indirect costs over the lifespan of those born with specific birth defects. Using an incidence approach, we made the most comprehensive estimates to date of the cost of 18 of the most clinically significant birth defects in the United States. Our analysis provides the basis for assessing competing strategies for research and prevention.

[1]  R. Scheffler,et al.  Prevention: the cost-effectiveness of the California Diabetes and Pregnancy Program. , 1992, American journal of public health.

[2]  N. Glass Economic Aspects of the Prevention of Down's Syndrome (Mongolism) , 1975 .

[3]  S. Chaikind,et al.  The impact of low birthweight on special education costs. , 1991, Journal of health economics.

[4]  M. Moore Patterns in Special Education Service Delivery and Cost. , 1988 .

[5]  Gordon S. Smith,et al.  COST OF INJURY IN THE UNITED STATES: A REPORT TO CONGRESS , 1989 .

[6]  Rice Dp,et al.  Estimating the cost of illness. , 1967 .

[7]  J. Pearn,et al.  Childhood deaths in Down's syndrome. Survival curves and causes of death from a total population study in Queensland, Australia, 1976 to 1985. , 1989, Journal of medical genetics.

[8]  E. Alberman,et al.  Cerebral palsy: why we must plan for survival. , 1990, Archives of disease in childhood.

[9]  Dorothy P. Rice,et al.  The economic costs of illness: A replication and update , 1985, Health care financing review.

[10]  Clifford Goodman,et al.  Physician Payment Review Commission , 1988 .

[11]  R. Fein Economics of mental illness , 1958 .

[12]  Rice Dp,et al.  The economic cost of illness revisited. , 1976 .

[13]  J. Ferrell Economics of Public Health. , 1927 .

[14]  S. Hagard,et al.  Screening for spina bifida cystica. A cost-benefit analysis. , 1976, British journal of preventive & social medicine.

[15]  S. Mushkin,et al.  Economic costs of disease and injury. , 1959, Public health reports.

[16]  Q. Malone Mortality and survival of the Down's syndrome population in Western Australia. , 2008, Journal of mental deficiency research.

[17]  D. C. Miller,et al.  Surgical repair of tetralogy of Fallot. Long-term follow-up with particular emphasis on late death and reoperation. , 1985, The Journal of thoracic and cardiovascular surgery.

[18]  P. Baird,et al.  Spina bifida and hydrocephalus: a population study over a 35-year period. , 1989, American journal of human genetics.

[19]  L. Cousins Etiology and prevention of congenital anomalies among infants of overt diabetic women. , 1991, Clinical obstetrics and gynecology.

[20]  Charles N. Smart,et al.  The incidence and economic costs of major health impairments: A comparative analysis of cancer, motor vehicle injuries, coronary heart disease, and stroke , 1982 .

[21]  Norman T. J. Bailey,et al.  Systems Aspects of Health Planning , 1976 .

[22]  A. Detsky,et al.  When does mass screening for open neural tube defects in low-risk pregnancies result in cost savings? , 1987, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[23]  C. Goodman Prospective Payment Assessment Commission , 1988 .