Rationale for treating primary Sjögren’s syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab)
暂无分享,去创建一个
V. Devauchelle | A. Saraux | E. Montero | C. Le Dantec | Yves Renaudineau | T. Fali | Ruby Alonso | Jacques Olivier Pers
[1] J. Pers,et al. Diagnostic value of labial minor salivary gland biopsy for Sjögren's syndrome: a systematic review. , 2013, Autoimmunity reviews.
[2] Namrata Singh,et al. The T cell in Sjogren's syndrome: force majeure, not spectateur. , 2012, Journal of autoimmunity.
[3] J. Pers,et al. B cells in Sjögren's syndrome: from pathophysiology to diagnosis and treatment. , 2012, Journal of autoimmunity.
[4] Y. Shoenfeld,et al. Low levels of vitamin-D are associated with neuropathy and lymphoma among patients with Sjögren's syndrome. , 2012, Journal of autoimmunity.
[5] J. Pers,et al. CD5 expression promotes multiple intracellular signaling pathways in B lymphocyte. , 2012, Autoimmunity reviews.
[6] J. Pers,et al. Epigenetics and Sjögren's syndrome. , 2012, Current pharmaceutical biotechnology.
[7] L. Essioux,et al. CD6 and Syntaxin Binding Protein 6 Variants and Response to Tumor Necrosis Factor Alpha Inhibitors in Danish Patients with Rheumatoid Arthritis , 2012, PloS one.
[8] J. Pers,et al. Neurological Disorders in Primary Sjögren's Syndrome , 2012, Autoimmune diseases.
[9] J. Anaya,et al. HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies. , 2012, Autoimmunity reviews.
[10] J. Pers,et al. In Sjögren's syndrome, B lymphocytes induce epithelial cells of salivary glands into apoptosis through protein kinase C delta activation. , 2012, Autoimmunity reviews.
[11] S. Davis,et al. CD6 attenuates early and late signaling events, setting thresholds for T-cell activation , 2011, European journal of immunology.
[12] E. Montero,et al. A clinical exploratory study with itolizumab, an anti-CD6 monoclonal antibody, in patients with rheumatoid arthritis. , 2012, Results in immunology.
[13] P. D. De Jager,et al. The CD6 Multiple Sclerosis Susceptibility Allele Is Associated with Alterations in CD4+ T Cell Proliferation , 2011, The Journal of Immunology.
[14] J. Reichert. Antibody-based therapeutics to watch in 2011 , 2011, mAbs.
[15] J. Pers,et al. Rationale for Targeting CD6 as a Treatment for Autoimmune Diseases , 2011, Arthritis.
[16] J. Ellwart,et al. The CD6 Scavenger Receptor Is Differentially Expressed on a CD56dim Natural Killer Cell Subpopulation and Contributes to Natural Killer-Derived Cytokine and Chemokine Secretion , 2010, Journal of Innate Immunity.
[17] L. Misery,et al. Memory B-cell aggregates in skin biopsy are diagnostic for primary Sjögren's syndrome. , 2010, Journal of autoimmunity.
[18] J. Pers,et al. Significance of B cells and B cell clonality in Sjögren's syndrome. , 2010, Arthritis and rheumatism.
[19] H. Moutsopoulos,et al. Characteristics of the minor salivary gland infiltrates in Sjögren's syndrome. , 2010, Journal of autoimmunity.
[20] J. Pers,et al. Epigenetics and autoimmunity. , 2010, Journal of autoimmunity.
[21] Ludwig Kappos,et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci , 2009, Nature Genetics.
[22] J. Pers,et al. Ectopic Germinal Centers Are Rare in Sjögren’s Syndrome Salivary Glands and Do Not Exclude Autoreactive B Cells1 , 2009, The Journal of Immunology.
[23] N. Patel,et al. Long-term outcomes of nonconditioned patients with severe combined immunodeficiency transplanted with HLA-identical or haploidentical bone marrow depleted of T cells with anti-CD6 mAb. , 2008, The Journal of allergy and clinical immunology.
[24] Glay Chinea,et al. Towards the definition of a chimpanzee and human conserved CD6 domain 1 epitope recognized by T1 monoclonal antibody. , 2008, Hybridoma.
[25] Danica Stanimirovic,et al. Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system , 2008, Nature Immunology.
[26] J. Pers,et al. BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjögren's syndrome. , 2007, Arthritis and rheumatism.
[27] A. Peixoto,et al. Extracellular Isoforms of CD6 Generated by Alternative Splicing Regulate Targeting of CD6 to the Immunological Synapse1 , 2007, The Journal of Immunology.
[28] B. Cochener,et al. Improvement of Sjögren's syndrome after two infusions of rituximab (anti-CD20). , 2007, Arthritis and rheumatism.
[29] J. Pers,et al. Identification of transitional type II B cells in the salivary glands of patients with Sjögren's syndrome. , 2006, Arthritis and rheumatism.
[30] P. Youinou,et al. Role of B-cell antigen receptor-associated molecules and lipid rafts in CD5-induced apoptosis of B CLL cells , 2005, Leukemia.
[31] R. Pérez,et al. Humanization of predicted T-cell epitopes reduces the immunogenicity of chimeric antibodies: new evidence supporting a simple method. , 2003, Hybridoma and hybridomics.
[32] R. Jonsson,et al. Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group , 2002, Annals of the rheumatic diseases.
[33] L. Beretta,et al. CD6: expression during development, apoptosis and selection of human and mouse thymocytes. , 2002, International immunology.
[34] T. Behrens,et al. Cd5 Maintains Tolerance in Anergic B Cells , 2000, The Journal of experimental medicine.
[35] E. Montero,et al. CD6 molecule may be important in the pathological mechanisms of lymphocytes adhesion to human skin in psoriasis and ior t1 MAb a possible new approach to treat this disease. , 1999, Autoimmunity.
[36] A. Grinberg,et al. CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity , 1998, The Journal of experimental medicine.
[37] D. Patel,et al. Cytokine-regulated expression of activated leukocyte cell adhesion molecule (CD166) on monocyte-lineage cells and in rheumatoid arthritis synovium. , 1998, Arthritis and rheumatism.
[38] H. Mellstedt,et al. CD6 ligation modulates the Bcl-2/Bax ratio and protects chronic lymphocytic leukemia B cells from apoptosis induced by anti-IgM. , 1997, Blood.
[39] T. Daniels. Labial salivary gland biopsy in Sjögren's syndrome. Assessment as a diagnostic criterion in 362 suspected cases. , 1984, Arthritis and rheumatism.