High gain signal averaged electrocardiogram combined with 24 hour monitoring in patients early after myocardial infarction for bedside prediction of arrhythmic events.

The value of the high gain, signal averaged electrocardiogram combined with 24 hour electrocardiographic monitoring in the prediction of arrhythmic events was assessed in 159 patients in the first week after myocardial infarction. Eleven patients (7%) suffered arrhythmic events during a mean (SD) of 12 (6) months of follow up (range 2-22, median 13 months). The combination of high gain, signal averaged electrocardiography and 24 hour electrocardiographic monitoring was more accurate than either technique alone or than clinical information collected during admission in predicting these events. The combination identified a high risk group of 13 (8%) patients, with an arrhythmic event rate of 62% and a low risk group with an event rate of 2%. The combination of high gain, signal averaged electrocardiography and 24 hour electrocardiographic monitoring in the first week after myocardial infarction provides a rapid, cheap, and non-invasive bedside method for the prediction of arrhythmias.

[1]  S L Winters,et al.  Optimal bandpass filters for time-domain analysis of the signal-averaged electrocardiogram. , 1987, The American journal of cardiology.

[2]  J. Uther,et al.  Changes in ventricular activation time on the signal-averaged electrocardiogram in the first year after acute myocardial infarction. , 1987, The American journal of cardiology.

[3]  S L Winters,et al.  A new noninvasive index to predict sustained ventricular tachycardia and sudden death in the first year after myocardial infarction: based on signal-averaged electrocardiogram, radionuclide ejection fraction and Holter monitoring. , 1987, Journal of the American College of Cardiology.

[4]  N. Sammel,et al.  Prediction of serious arrhythmic events after myocardial infarction: signal-averaged electrocardiogram, Holter monitoring and radionuclide ventriculography. , 1987, Journal of the American College of Cardiology.

[5]  D L Ross,et al.  Prognostic significance of ventricular tachycardia and fibrillation induced at programmed stimulation and delayed potentials detected on the signal-averaged electrocardiograms of survivors of acute myocardial infarction. , 1986, Circulation.

[6]  J. Brachmann,et al.  Day to day variations in morphology and duration of fragmented ventricular potentials during the late post-myocardial infarction phase in conscious dogs. , 1985, European heart journal.

[7]  M. Josephson,et al.  Identification of patients with ventricular tachycardia after myocardial infarction: signal-averaged electrocardiogram, Holter monitoring, and cardiac catheterization. , 1984, Circulation.

[8]  A. Jaffe,et al.  Risk factors for sudden death after acute myocardial infarction: two-year follow-up. , 1984, The American journal of cardiology.

[9]  J P Miller,et al.  The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction. , 1984, Circulation.

[10]  M Borggrefe,et al.  Prognostic significance of late ventricular potentials after acute myocardial infarction. , 1983, European heart journal.

[11]  A H Harken,et al.  Relation between late potentials on the body surface and directly recorded fragmented electrograms in patients with ventricular tachycardia. , 1983, The American journal of cardiology.

[12]  M. Simson.  Use of Signals in the Terminal QRS Complex to Identify Patients with Ventricular Tachycardia After Myocardial Infarction , 1981, Circulation.

[13]  A. Moss,et al.  Survivorship patterns in the posthospital phase of myocardial infarction. , 1979, Circulation.

[14]  B. Lown,et al.  Sudden cardiac death: the major challenge confronting contemporary cardiology. , 1979, The American journal of cardiology.

[15]  J. Bigger,et al.  Limitations of the Lown grading system for study of human ventricular arrhythmias. , 1977, American heart journal.

[16]  R Lazzara,et al.  Re‐entrant Ventricular Arrhythmias in the Late Myocardial Infarction Period: 2. Patterns of Initiation and Termination of Re‐entry , 1977, Circulation.

[17]  P. Brandt,et al.  A new coronary prognostic index. , 1969, American heart journal.

[18]  T. Killip,et al.  Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients. , 1967, The American journal of cardiology.