Breathlessness In The Elderly During The Last Year Of Life Sufficient To Restrict Activity

BREATHLESSNESS IN THE ELDERLY DURING THE LAST YEAR OF LIFE SUFFICIENT TO RESTRICT ACTIVITY: PREVALENCE, PATTERN AND ASSOCIATED FACTORS. Authors: Miriam J Johnson1 MD Professor in Palliative Medicine, J Martin Bland2, Ph.D., Prof of Health Statistics, Evelyne A Gahbauer3, MD, MPH Senior Data Manager Magnus Ekström4 PhD Postdoctoral research fellow, Aynharan Sinnarajah5 MD, MPH Medical Director, Thomas M Gill3 MD Humana Foundation Professor of Medicine (Geriatrics) and Professor of Epidemiology (Chronic Diseases) and of Investigative Medicine David C Currow4 PhD Professor. 1Hull York Medical School, University of Hull, UK; 2University of York UK; 3 Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; 4 Discipline of Palliative and Supportive Services, Flinders University, Adelaide, Australia; 5 Palliative & End of Life Care, Alberta Health Services (AHS) Calgary Zone, Canada.

[1]  J. Steward,et al.  Dyspnoea and mortality in older people in the community: a 10-year follow-up. , 2012, Age and ageing.

[2]  Susan C. Miller,et al.  Prediction of 6-month survival of nursing home residents with advanced dementia using ADEPT vs hospice eligibility guidelines. , 2010, JAMA.

[3]  L. Fried,et al.  Frailty in older adults: evidence for a phenotype. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

[4]  N. Christakis,et al.  Factors considered important at the end of life by patients, family, physicians, and other care providers. , 2000, JAMA.

[5]  Christianna S. Williams,et al.  Restricted Activity among Community-Living Older Persons: Incidence, Precipitants, and Health Care Utilization , 2001, Annals of Internal Medicine.

[6]  A. Gulsvik,et al.  Respiratory symptoms as predictors of all‐cause mortality in an urban community: a 30‐year follow‐up , 2006, Journal of internal medicine.

[7]  J. Guenette,et al.  Sex differences in exertional dyspnea in patients with mild COPD: Physiological mechanisms , 2011, Respiratory Physiology & Neurobiology.

[8]  R. Abbott,et al.  Relationships Between Respiratory Symptoms and FEV1 in Men and Women with Normal Lung Function: The Korean Health and Genome Study , 2005, Lung.

[9]  Suzanne G. Leveille,et al.  Preventing disability and falls in older adults: a population-based randomized trial. , 1994, American journal of public health.

[10]  Miriam J. Johnson,et al.  Prevalence and assessment of breathlessness in the clinical setting , 2014, Expert review of respiratory medicine.

[11]  S. Karlsen,et al.  A comparison of the palliative care needs of patients dying from chronic respiratory diseases and lung cancer , 2001, Palliative medicine.

[12]  J. Geraci,et al.  Progressive disease in patients with cancer presenting to an emergency room with acute symptoms predicts short-term mortality , 2006, Supportive Care in Cancer.

[13]  A. Abernethy,et al.  Do the trajectories of dyspnea differ in prevalence and intensity by diagnosis at the end of life? A consecutive cohort study. , 2010, Journal of pain and symptom management.

[14]  A. Buist,et al.  Predictors of dyspnoea prevalence: results from the BOLD study , 2013, European Respiratory Journal.

[15]  J. Guralnik,et al.  Patterns of functional decline at the end of life. , 2003, JAMA.

[16]  I. Higginson,et al.  Are there differences in the prevalence of palliative care-related problems in people living with advanced cancer and eight non-cancer conditions? A systematic review. , 2014, Journal of pain and symptom management.

[17]  Suzanne G. Leveille,et al.  Preventing Disability and Managing Chronic Illness in Frail Older Adults: A Randomized Trial of a Community‐Based Partnership with Primary Care , 1998, Journal of the American Geriatrics Society.

[18]  Thomas M Gill,et al.  Transitions between frailty states among community-living older persons. , 2006, Archives of internal medicine.

[19]  I. Higginson,et al.  Are bereaved family members a valid proxy for a patient's assessment of dying? , 1994, Social science & medicine.

[20]  M. Buchalter,et al.  Dyspnoea and quality of life in older people at home. , 2001, Age and ageing.

[21]  A. Abernethy,et al.  Predictors of chronic breathlessness: a large population study , 2011, BMC public health.

[22]  A. Gulsvik,et al.  Respiratory symptoms and 30 year mortality from obstructive lung disease and pneumonia , 2006, Thorax.

[23]  Stefania Costi,et al.  Effects of a walking aid in COPD patients receiving oxygen therapy. , 2007, Chest.

[24]  A. Abernethy,et al.  A community population survey of prevalence and severity of dyspnea in adults. , 2009, Journal of pain and symptom management.

[25]  C. Janson,et al.  Dyspnea in relation to symptoms of anxiety and depression: A prospective population study. , 2006, Respiratory medicine.

[26]  J. Lynn,et al.  Trajectories of disability in the last year of life. , 2010, The New England journal of medicine.

[27]  W. Katon,et al.  The impact of major depression on chronic medical illness. , 1996, General hospital psychiatry.

[28]  T. Weiland,et al.  Verbal dyspnoea score predicts emergency department departure status in patients with shortness of breath , 2010, Emergency medicine Australasia : EMA.

[29]  M. Tamburini,et al.  Karnofsky and ECOG performance status scoring in lung cancer: a prospective, longitudinal study of 536 patients from a single institution. , 1996, European journal of cancer.

[30]  I. Higginson,et al.  Is a specialist breathlessness service more effective and cost-effective for patients with advanced cancer and their carers than standard care? Findings of a mixed-method randomised controlled trial , 2014, BMC Medicine.

[31]  J. Halter,et al.  Daily Symptoms and Behavioral Responses: Results of a Health Diary with Older Adults , 1988, Medical care.

[32]  D. Reuben,et al.  A Randomized Clinical Trial of Outpatient Comprehensive Geriatric Assessment Coupled with an Intervention to Increase Adherence to Recommendations , 1999, Journal of the American Geriatrics Society.

[33]  S. Cummings,et al.  Effect of alendronate on limited-activity days and bed-disability days caused by back pain in postmenopausal women with existing vertebral fractures. Fracture Intervention Trial Research Group. , 2000, Archives of internal medicine.

[34]  A. Abernethy,et al.  Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea , 2003, BMJ : British Medical Journal.

[35]  E. C. Hammond,et al.  SOME PRELIMINARY FINDINGS ON PHYSICAL COMPLAINTS FROM A PROSPECTIVE STUDY OF 1,064,004 MEN AND WOMEN. , 1964, American journal of public health and the nation's health.

[36]  S. Dunbar,et al.  Heart Failure Symptom Assessment and Management: Can Caregivers Serve as Proxy? , 2010, The Journal of cardiovascular nursing.

[37]  Dror Ofir,et al.  Sex differences in the perceived intensity of breathlessness during exercise with advancing age. , 2008, Journal of applied physiology.

[38]  D. Atar,et al.  Evaluation of dyspnoea in a sample of elderly subjects recruited from general practice , 2007, International journal of clinical practice.

[39]  I. Higginson,et al.  A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. , 2006, Journal of pain and symptom management.

[40]  I. Higginson,et al.  Understanding breathlessness: cross-sectional comparison of symptom burden and palliative care needs in chronic obstructive pulmonary disease and cancer. , 2010, Journal of palliative medicine.

[41]  C. Ripamonti,et al.  Management of dyspnea in advanced cancer patients , 1999, Supportive Care in Cancer.

[42]  Surgeon General,et al.  Healthy people : the Surgeon General's report on health promotion and disease prevention , 1979 .

[43]  Miriam J. Johnson,et al.  Researching breathlessness in palliative care: consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup , 2009, Palliative medicine.