Ligand-gated ion channels
暂无分享,去创建一个
Christoph Weise | D. Purves | L. C. Katz | J. McNamara | G. Augustine | A. LaMantia | D. Fitzpatrick | A. Friday | F. Hucho | C. Weise | Ferdinand Hucho | V. Cockcroft | S Mark Williams | G. G. Lunt | D. J. Osguthorpe | E. A. Barnard
[1] R. Dingledine,et al. Identification of a site in glutamate receptor subunits that controls calcium permeability , 1991, Science.
[2] Diying Huang,et al. An early Cambrian craniate-like chordate , 1999, Nature.
[3] M. Sheng,et al. Ligand-gated ion channel interactions with cytoskeletal and signaling proteins. , 2000, Annual review of physiology.
[4] D C Rees,et al. Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel. , 1998, Science.
[5] B. Chait,et al. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. , 1998, Science.
[6] A. Goldman,et al. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein , 1991, Science.
[7] Terri L. Gilbert,et al. The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins , 1993, Neuron.
[8] M. Eisenstein,et al. How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors. , 2000, Trends in pharmacological sciences.
[9] S. Heinemann,et al. Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins , 1994, Neuron.
[10] K. Keay,et al. Structural motif and characteristics of the extracellular domain of P2X receptors. , 1997, Biochemical and biophysical research communications.
[11] R. Dingledine,et al. The glutamate receptor ion channels. , 1999, Pharmacological reviews.
[12] N. Unwin. Acetylcholine receptor channel imaged in the open state , 1995, Nature.
[13] A. Karlin,et al. Substituted-cysteine accessibility method. , 1998, Methods in enzymology.
[14] L. Hood,et al. Acetylcholine receptor: complex of homologous subunits. , 1980, Science.
[15] R. North,et al. Pore dilation of neuronal P2X receptor channels , 1999, Nature Neuroscience.
[16] F. Hucho,et al. The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor. , 1996, European journal of biochemistry.
[17] H. Hirai,et al. Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit , 1997, Neuron.
[18] S. Sine,et al. Molecular Dissection of Subunit Interfaces in the Acetylcholine Receptor , 1996, The Journal of Biological Chemistry.
[19] R. Beroukhim,et al. Ultrastructure of the 5‐Hydroxytryptamine3 Receptor , 1995, Journal of neurochemistry.
[20] S. Rhee,et al. Molecular Cloning, Splice Variants, Expression, and Purification of Phospholipase C-4 (*) , 1996, The Journal of Biological Chemistry.
[21] A. Vincent,et al. Genes at the junction – candidates for congenital myasthenic syndromes , 1997, Trends in Neurosciences.
[22] B. Fakler,et al. Gating of inward-rectifier K+ channels by intracellular pH. , 2000, European journal of biochemistry.
[23] F. Hucho,et al. Anionic subsites of the acetylcholinesterase from Torpedo californica: affinity labelling with the cationic reagent N,N‐dimethyl‐2‐phenyl‐aziridinium. , 1990, The EMBO journal.
[24] Richard J. Evans,et al. The Role of Positively Charged Amino Acids in ATP Recognition by Human P2X1 Receptors* , 2000, The Journal of Biological Chemistry.
[25] T. Sixma,et al. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors , 2001, Nature.
[26] R. Huganir,et al. Phosphorylation of the Nicotinic Acetylcholine Receptor by Protein Tyrosine Kinases a , 1995, Annals of the New York Academy of Sciences.
[27] A. Malafosse,et al. A nonsense mutation in the α4 subunit of the nicotinic acetylcholine receptor (CHRNA4) cosegregates with 20q-linked benign neonatal familial convulsions (EBNI) , 1994, Neurobiology of Disease.
[28] L. Jan,et al. Taking Apart the Gating of Voltage-Gated K+ Channels , 2000, Neuron.
[29] D. Langosch,et al. Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[30] Y. J. Sun,et al. The structure of glutamine-binding protein complexed with glutamine at 1.94 A resolution: comparisons with other amino acid binding proteins. , 1998, Journal of molecular biology.
[31] F. Hucho,et al. The handedness of the subunit arrangement of the nicotinic acetylcholine receptor from Torpedo californica. , 1995, European journal of biochemistry.
[32] E. Gouaux,et al. Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor Crystal Structures of the GluR2 Ligand Binding Core , 2000, Neuron.
[33] S. Grant,et al. Proteomic analysis of NMDA receptor–adhesion protein signaling complexes , 2000, Nature Neuroscience.
[34] R. North,et al. Identification of amino acid residues contributing to the pore of a P2X receptor , 1997, The EMBO journal.
[35] A. Nicke,et al. P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand‐gated ion channels , 1998, The EMBO journal.
[36] M. Mark,et al. G-protein mediated gating of inward-rectifier K+ channels. , 2000, European journal of biochemistry.
[37] Henry A. Lester,et al. State-dependent cross-inhibition between transmitter-gated cation channels , 2000, Nature.
[38] Rolf Hilgenfeld,et al. The selectivity filter of a ligand‐gated ion channel , 1989, FEBS letters.
[39] C. January,et al. Internet resources for exploring gene family diversity. , 2000, TIPS - Trends in Pharmacological Sciences.
[40] D. Kirsch,et al. Photolabeling reveals the proximity of the alpha-neurotoxin binding site to the M2 helix of the ion channel in the nicotinic acetylcholine receptor. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[41] T. Vorherr,et al. The calmodulin-binding domain mediates the self-association of the plasma membrane Ca2+ pump. , 1991, The Journal of biological chemistry.
[42] T. Egan,et al. Hetero-oligomeric Assembly of P2X Receptor Subunits , 1999, The Journal of Biological Chemistry.
[43] G. Coruzzi,et al. Molecular evolution of glutamate receptors: a primitive signaling mechanism that existed before plants and animals diverged. , 1999, Molecular biology and evolution.
[44] B. Sakmann,et al. Location of a δ-subunit region determining ion transport through the acetylcholine receptor channel , 1986, Nature.
[45] K. Keinänen,et al. Molecular dissection of the agonist binding site of an AMPA receptor. , 1995, The EMBO journal.
[46] R. Sparkes,et al. Startle disease, or hyperekplexia: Response to clonazepam and assignment of the gene (STHE) to chromosome 5q by linkage analysis , 1992, Annals of neurology.
[47] A. Karlin,et al. Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the α subunit , 1994, Neuron.
[48] B. Sakmann,et al. Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance , 1988, Nature.
[49] G. Coruzzi,et al. Glutamate-receptor genes in plants , 1998, Nature.
[50] B. Sakmann,et al. Threonine in the selectivity filter of the acetylcholine receptor channel. , 1992, Biophysical journal.
[51] K. Mikoshiba,et al. Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[52] H. Lester,et al. Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor. , 1988, Science.
[53] A. Karlin,et al. The Location of the Gate in the Acetylcholine Receptor Channel , 1998, Neuron.
[54] J. Changeux,et al. Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[55] S. Sine. Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[56] P. Seeburg,et al. Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits. , 1988, Science.
[57] Baukrowitz. Inward rectifier potassium channels and a multitude of intracellular gating molecules , 2000, European Journal of Biochemistry.
[58] J. Changeux,et al. Allosteric transitions of the acetylcholine receptor. , 1998, Advances in protein chemistry.
[59] Nicolas Le Novère,et al. The Ligand Gated Ion Channel Database , 1999, Nucleic Acids Res..
[60] Richard L. Huganir,et al. GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors , 1997, Nature.
[61] F. Lottspeich,et al. The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits , 1986 .
[62] Y. Fujiyoshi,et al. Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall. , 1999, Journal of molecular biology.
[63] J. Changeux,et al. Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation. , 1999, Biophysical journal.
[64] Miriam Eisenstein,et al. Identification of the Amino Acid Subsets Accounting for the Ligand Binding Specificity of a Glutamate Receptor , 1996, Neuron.
[65] A. Karlin,et al. Structure of the Nicotinic Receptor Acetylcholine-binding Site , 1995, The Journal of Biological Chemistry.
[66] Baljit S Khakh,et al. Dynamic Selectivity Filters in Ion Channels , 1999, Neuron.
[67] K. Keinänen,et al. Ligand recognition in glutamate receptors: insights from mutagenesis of the soluble alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-binding domain of glutamate receptor type D (GluR-D). , 1997, Biochemical Society Transactions.
[68] A. Karlin,et al. Acetylcholine receptor binding site contains a disulfide cross-link between adjacent half-cystinyl residues. , 1986, The Journal of biological chemistry.
[69] E. Michaelis. Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging , 1998, Progress in Neurobiology.
[70] Xiaodong Wang,et al. Nucleotide Requirements for the in Vitro Activation of the Apoptosis Protein-activating Factor-1-mediated Caspase Pathway* , 2000, The Journal of Biological Chemistry.
[71] J. Changeux,et al. Stratification of the channel domain in neurotransmitter receptors. , 1993, Current opinion in cell biology.
[72] C. Bigge. Ionotropic glutamate receptors. , 1999, Current opinion in chemical biology.
[73] A. Vincent,et al. Molecular targets for autoimmune and genetic disorders of neuromuscular transmission. , 2000, European journal of biochemistry.
[74] F. Hucho. Molecular weight and quaternary structure of the cholinergic receptor protein extracted by detergents from Electrophorus electricus electric tissue , 1973, FEBS letters.
[75] Jean-Luc Galzi,et al. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic , 1992, Nature.
[76] H. Betz,et al. Evidence for a Tetrameric Structure of Recombinant NMDA Receptors , 1998, The Journal of Neuroscience.
[77] J. Changeux,et al. Chimaeric nicotinic–serotonergic receptor combines distinct ligand binding and channel specificities , 1993, Nature.
[78] W. Catterall,et al. Selectivity of cations and nonelectrolytes for acetylcholine-activated channels in cultured muscle cells , 1978, The Journal of general physiology.
[79] Jean-Luc Galzi,et al. Neurotransmitter-gated ion channels as unconventional allosteric proteins , 1994 .
[80] S. Heinemann,et al. Molecular Neurobiology and Genetics: Investigation of Neural Function and Dysfunction , 1998, Neuron.
[81] E. Kawashima,et al. The Cytolytic P2Z Receptor for Extracellular ATP Identified as a P2X Receptor (P2X7) , 1996, Science.
[82] A. Herrmann,et al. How do acetylcholine receptor ligands reach their binding sites? , 1999, European journal of biochemistry.
[83] T. Sixma,et al. A glia-derived acetylcholine-binding protein that modulates synaptic transmission , 2001, Nature.
[84] D. A. Dougherty,et al. The Cationminus signpi Interaction. , 1997, Chemical reviews.
[85] P. Seeburg. The Role of RNA Editing in Controlling Glutamate Receptor Channel Properties , 1996, Journal of neurochemistry.
[86] Werner Hoch,et al. Formation of the neuromuscular junction , 1999 .
[87] D. Osguthorpe,et al. Modeling of agonist binding to the ligand‐gated ion channel superfamily of receptors , 1990, Proteins.
[88] P. Seeburg,et al. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels , 1991, Cell.
[89] E. Perozo,et al. Structural rearrangements underlying K+-channel activation gating. , 1999, Science.
[90] B. Fakler,et al. Polyamines as gating molecules of inward-rectifier K+ channels. , 2000, European journal of biochemistry.
[91] A. Nicke,et al. Molecular determinants of glycine receptor subunit assembly , 1999, The EMBO journal.
[92] E. Gouaux,et al. Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct , 1998, Protein science : a publication of the Protein Society.
[93] T. Egan,et al. A Domain Contributing to the Ion Channel of ATP-Gated P2X2 Receptors Identified by the Substituted Cysteine Accessibility Method , 1998, The Journal of Neuroscience.
[94] R. North,et al. Families of ion channels with two hydrophobic segments. , 1996, Current opinion in cell biology.
[95] B. Fakler,et al. KATP channels gated by intracellular nucleotides and phospholipids. , 2000, European journal of biochemistry.
[96] S. Muallem,et al. The N-terminal domain of the IP3 receptor gates store-operated hTrp3 channels. , 1999, Molecular cell.
[97] P P Humphrey,et al. International Union of Pharmacology. XIX. The IUPHAR receptor code: a proposal for an alphanumeric classification system. , 1998, Pharmacological reviews.
[98] N. Brandon,et al. GABAA-receptor-associated protein links GABAA receptors and the cytoskeleton , 1999, Nature.
[99] Lixin Tang,et al. Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors , 1995, Nature.
[100] E. Gouaux,et al. Structure of a glutamate-receptor ligand-binding core in complex with kainate , 1998, Nature.
[101] P. H. Barry,et al. M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective. , 2000, Biophysical journal.
[102] D. Bertrand,et al. A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX , 1990, Neuron.
[103] P. Seeburg,et al. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. , 1995, Science.
[104] I. Scheffer,et al. A missense mutation in the neuronal nicotinic acetylcholine receptor α4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy , 1995, Nature Genetics.
[105] D. A. Dougherty,et al. From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[106] R. North,et al. Ionic permeability of, and divalent cation effects on, two ATP‐gated cation channels (P2X receptors) expressed in mammalian cells. , 1996, The Journal of physiology.
[107] N. Nayeem,et al. Quaternary Structure of the Native GABAA Receptor Determined by Electron Microscopic Image Analysis , 1994, Journal of neurochemistry.
[108] N. Unwin. Nicotinic acetylcholine receptor at 9 A resolution. , 1993, Journal of molecular biology.
[109] D. Julius,et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway , 1997, Nature.
[110] Eric Gouaux,et al. Functional characterization of a potassium-selective prokaryotic glutamate receptor , 1999, Nature.
[111] K. Palczewski,et al. Crystal Structure of Rhodopsin: A G‐Protein‐Coupled Receptor , 2002, Chembiochem : a European journal of chemical biology.
[112] A. Karlin,et al. Identification of acetylcholine receptor channel-lining residues in the M1 segment of the beta-subunit. , 1995, Biochemistry.
[113] Henry A. Lester,et al. Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds , 1999, Nature Neuroscience.
[114] J. Changeux,et al. Mutational Analysis of the Charge Selectivity Filter of the α7 Nicotinic Acetylcholine Receptor , 1999, Neuron.
[115] R. Huganir,et al. Protein phosphorylation of ligand-gated ion channels. , 1999, Methods in enzymology.