Causes of dysphagia among different age groups: a systematic review of the literature.

Dysphagia is a common problem that has the potential to result in severe complications such as malnutrition and aspiration pneumonia. Based on the complexity of swallowing, there may be many different causes. This article presents a systematic literature review to assess different comorbid disease associations with dysphagia based on age. The causes of dysphagia are different depending on age, affecting between 1.7% and 11.3% of the general population. Dysphagia can be a symptom representing disorders pertinent to any specialty of medicine. This review can be used to aid in the diagnosis of patients presenting with the complaint of dysphagia.

[1]  Michael J Lee,et al.  Risk factors for dysphagia after anterior cervical spine surgery: a two-year prospective cohort study. , 2007, The spine journal : official journal of the North American Spine Society.

[2]  J. Holland,et al.  Swallowing Function after Chemoradiation for Advanced Stage Oropharyngeal Cancer , 2004 .

[3]  A. Dursun,et al.  Is there an association between Helicobacter pylori in the inlet patch and globus sensation? , 2010, World journal of gastroenterology.

[4]  S. Wadler,et al.  Decreased short- and long-term swallowing problems with altered radiotherapy dosing used in an organ-sparing protocol for advanced pharyngeal carcinoma. , 2004, Archives of otolaryngology--head & neck surgery.

[5]  Takayuki Matsumoto,et al.  Non-erosive reflux disease rather than cervical inlet patch involves globus , 2010, Journal of Gastroenterology.

[6]  Sang Woo Lee,et al.  Prevalence and endoscopic features of eosinophilic esophagitis in patients with esophageal or upper gastrointestinal symptoms , 2012, Journal of digestive diseases.

[7]  J. Verschuuren,et al.  Detecting dysphagia in inclusion body myositis , 2009, Journal of Neurology.

[8]  R. Tamargo,et al.  Prevalence, Characteristics, and Management of Swallowing Disorders following Cerebellopontine Angle Surgery , 2012, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[9]  D. Seripa,et al.  Clinical Features of Reflux Esophagitis in Older People: A Study of 840 Consecutive Patients , 2006, Journal of the American Geriatrics Society.

[10]  P. Devitt,et al.  Single center prospective randomized trial of laparoscopic Nissen versus anterior 90 degrees fundoplication. , 2006, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.

[11]  Ling Gao,et al.  Presentations and management of thyroglossal duct cyst in children versus adults: a review of 106 cases. , 2011, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[12]  N. Mattek,et al.  Endoscopic Findings in Patients Presenting with Dysphagia: Analysis of a National Endoscopy Database , 2012, Dysphagia.

[13]  M. Majdan,et al.  Gastrointestinal involvement in patients with systemic sclerosis. , 2010, Polskie Archiwum Medycyny Wewnetrznej.

[14]  J. Pandolfino,et al.  Hyperdynamic Upper Esophageal Sphincter Pressure: A Manometric Observation in Patients Reporting Globus Sensation , 2009, The American Journal of Gastroenterology.

[15]  I. Aydogdu,et al.  Oropharyngeal swallowing in craniocervical dystonia , 2002, Journal of neurology, neurosurgery, and psychiatry.

[16]  H. El‐Serag,et al.  Systematic review: the epidemiology of eosinophilic oesophagitis in adults , 2010, Alimentary pharmacology & therapeutics.

[17]  R. V. Smith,et al.  Long-term swallowing problems after organ preservation therapy with concomitant radiation therapy and intravenous hydroxyurea: initial results. , 2000, Archives of otolaryngology--head & neck surgery.

[18]  B. Miller,et al.  Dysphagia in patients with frontotemporal lobar dementia. , 2007, Archives of neurology.

[19]  P. Vos,et al.  Dysphagia following chemoradiation for locally advanced head and neck cancer. , 2004, Annals of oncology : official journal of the European Society for Medical Oncology.

[20]  D. Tibboel,et al.  Dysphagia in children with severe generalized cerebral palsy and intellectual disability , 2008, Developmental medicine and child neurology.

[21]  Mark Speechley,et al.  Dysphagia After Stroke: Incidence, Diagnosis, and Pulmonary Complications , 2005, Stroke.

[22]  I. Hirano,et al.  Temporal trends in the relative prevalence of dysphagia etiologies from 1999-2009. , 2012, World journal of gastroenterology.

[23]  B. Latal,et al.  Prevalence and predictors of later feeding disorders in children who underwent neonatal cardiac surgery for congenital heart disease , 2011, Cardiology in the Young.

[24]  A. Minagar,et al.  Oropharyngeal dysphagia in multiple sclerosis , 2010, Multiple sclerosis.

[25]  P. Belafsky,et al.  Causes of Dysphagia in a Tertiary-Care Swallowing Center , 2013, The Annals of otology, rhinology, and laryngology.

[26]  K. Chua,et al.  Functional outcome in brain stem stroke patients after rehabilitation. , 1996, Archives of physical medicine and rehabilitation.

[27]  C. Mavroudis,et al.  The incidence of dysphagia in pediatric patients after open heart procedures with transesophageal echocardiography. , 2003, The Annals of thoracic surgery.

[28]  Tyng-Guey Wang,et al.  Dysphagia in patients with brainstem stroke: incidence and outcome. , 2000, American journal of physical medicine & rehabilitation.

[29]  R. Genta,et al.  Lymphocytic oesophagitis: clinicopathological aspects of an emerging condition , 2011, Gut.

[30]  C. Corless,et al.  Pediatric eosinophilic esophagitis: Single‐center experience in northwestern USA , 2009 .

[31]  S. Barczi,et al.  How Should Dysphagia Care of Older Adults Differ? Establishing Optimal Practice Patterns , 2000, Seminars in speech and language.

[32]  D. Gotley,et al.  Symptoms, investigations and management of patients with cancer of the oesophagus and gastro‐oesophageal junction in Australia , 2010, The Medical journal of Australia.

[33]  Pablo Martinez-Martin,et al.  Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; Study using nonmotor symptoms questionnaire in 545 patients , 2007, Movement disorders : official journal of the Movement Disorder Society.

[34]  D. Katzka,et al.  Eosinophilic esophagitis: a prevalent disease in the United States that affects all age groups. , 2008, Gastroenterology.

[35]  Giovanni M. Lujan,et al.  Gastric heterotopia in the proximal oesophagus ("inlet patch"): Association with adenocarcinomas arising in Barrett mucosa. , 2012, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[36]  R. Martino,et al.  Incidence and impact of dysphagia in patients receiving prolonged endotracheal intubation after cardiac surgery. , 2009, Canadian journal of surgery. Journal canadien de chirurgie.

[37]  L. Hartelius,et al.  Speech and swallowing symptoms associated with Parkinson's disease and multiple sclerosis: a survey. , 1994, Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics.

[38]  C. Pedace,et al.  Oropharyngeal dysphagia after stroke: incidence, diagnosis, and clinical predictors in patients admitted to a neurorehabilitation unit. , 2009, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

[39]  A. Straumann,et al.  Eosinophilic esophagitis: escalating epidemiology? , 2005, The Journal of allergy and clinical immunology.

[40]  I R Odderson,et al.  Swallow management in patients on an acute stroke pathway: quality is cost effective. , 1995, Archives of physical medicine and rehabilitation.

[41]  E. Dejaeger,et al.  Dysphagia in multiple sclerosis , 2002, Clinical Neurology and Neurosurgery.

[42]  R. Ramakrishnan,et al.  Eosinophilic oesophagitis in adults , 2008, Histopathology.

[43]  Paula Cristina Cola,et al.  Incidência de disfagia orofaríngea após acidente vascular encefálico em hospital público de referência , 2004 .

[44]  S. Paolucci,et al.  Dysphagia in multiple sclerosis – prevalence and prognostic factors , 2002, Acta neurologica Scandinavica.

[45]  F. Mastaglia,et al.  Pharyngeal Dysphagia in Inflammatory Muscle Diseases Resulting from Impaired Suprahyoid Musculature , 2012, Dysphagia.

[46]  T. Wilkins,et al.  The Prevalence of Dysphagia in Primary Care Patients: A HamesNet Research Network Study , 2007, The Journal of the American Board of Family Medicine.

[47]  Khader N. Mustafa,et al.  Clinical characteristics and outcomes of patients with idiopathic inflammatory myopathies from Jordan 1996–2009 , 2010, Clinical Rheumatology.

[48]  P. Davidson,et al.  Functional impairment severity is associated with health status among older persons with intellectual disability and cerebral palsy. , 2009, Journal of intellectual disability research : JIDR.

[49]  M. Sabbagh,et al.  Health Care Utilization and Costs Among Patients With AD With and Without Dysphagia , 2013, Alzheimer disease and associated disorders.

[50]  A. Auchus,et al.  Autonomic dysfunction in Parkinson's disease: a comprehensive symptom survey. , 2002, Parkinsonism & related disorders.

[51]  김향희.  Dysphagia in patients with dementia: Alzheimer versus vascular , 2009 .

[52]  R. Weichselbaum,et al.  Swallowing function in patients with head and neck cancer prior to treatment. , 2000, Archives of otolaryngology--head & neck surgery.

[53]  C. Clarke,et al.  Referral criteria for speech and language therapy assessment of dysphagia caused by idiopathic Parkinson's disease , 1998, Acta neurologica Scandinavica.

[54]  M. Kodaira,et al.  Prospective evaluation of incidence and severity of oral mucositis induced by conventional chemotherapy in solid tumors and malignant lymphomas , 2012, Supportive Care in Cancer.

[55]  Jimmy J Caudell,et al.  Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck. , 2010, International journal of radiation oncology, biology, physics.

[56]  G. Perotti,et al.  Scintigraphic evaluation of Zenker's diverticulum , 2003, European Journal of Nuclear Medicine and Molecular Imaging.

[57]  T. Smyrk,et al.  Prevalence and Predictive Factors of Eosinophilic Esophagitis in Patients Presenting With Dysphagia: A Prospective Study , 2007, The American Journal of Gastroenterology.

[58]  Maja O’Connor.  LONGITUDINAL STUDY , 2013 .

[59]  M. Heckman,et al.  Esophageal spasm: demographic, clinical, radiographic, and manometric features in 108 patients. , 2012, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[60]  R. McGlinchey,et al.  Antipsychotics and Oropharyngeal Dysphagia in Hospitalized Older Patients , 2008, Journal of clinical psychopharmacology.

[61]  R. Wong,et al.  Prevalence of eosinophilic esophagitis in an adult population undergoing upper endoscopy: a prospective study. , 2009, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[62]  LeiDong,et al.  Epidemiology of gastroesophageal reflux disease： A general population-based study in Xi＇an of Northwest China , 2004 .

[63]  B. Bloem,et al.  Prevalence of subjective dysphagia in community residents aged over 87. , 1990, BMJ.

[64]  R. Walker,et al.  Self-Reported Dysphagia and Its Correlates Within a Prevalent Population of People with Parkinson’s Disease , 2011, Dysphagia.

[65]  J. Fang,et al.  Eosinophilic oesophagitis in patients presenting with dysphagia – a prospective analysis , 2008, Alimentary pharmacology & therapeutics.

[66]  L. Dawson,et al.  Objective assessment of swallowing dysfunction and aspiration after radiation concurrent with chemotherapy for head-and-neck cancer. , 2002, International journal of radiation oncology, biology, physics.

[67]  M. Patti,et al.  Clinical, Radiological, and Manometric Profile in 145 Patients with Untreated Achalasia , 2008, World Journal of Surgery.

[68]  I Litvan,et al.  Progression of dysarthria and dysphagia in postmortem-confirmed parkinsonian disorders. , 2001, Archives of neurology.

[69]  Y. Yamasaki,et al.  Incidence and predictive factors for malignancies in 136 Japanese patients with dermatomyositis, polymyositis and clinically amyopathic dermatomyositis , 2011, Modern rheumatology.

[70]  M. Barawi,et al.  Eosinophilic esophagitis in children and adolescents: epidemiology, clinical presentation and seasonal variation , 2012, Journal of Gastroenterology.

[71]  J. Ringers,et al.  The effect of laparoscopic partial fundoplication on dysphagia, esophageal and lower esophageal sphincter motility. , 2007, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[72]  N. Talley,et al.  Dysphagia: epidemiology, risk factors and impact on quality of life – a population‐based study , 2008, Alimentary pharmacology & therapeutics.

[73]  T. Wittmann,et al.  Regional differences in the manifestation of gastrointestinal motor disorders in type 1 diabetic patients with autonomic neuropathy. , 2004, Zeitschrift fur Gastroenterologie.

[74]  P. Vos,et al.  Analysis of the factors influencing dysphagia severity upon diagnosis of head and neck cancer. , 2008, The British journal of radiology.

[75]  A. Ahuja,et al.  Dysphagia in treated nasopharyngeal cancer , 2000, Head & neck.

[76]  L. Cozzi,et al.  Early Morbidity after Radiotherapy with or without Chemotherapy in Advanced Head and Neck Cancer , 2003, Strahlentherapie und Onkologie.

[77]  M. Thomson,et al.  Eosinophils in the oesophageal mucosa: clinical, pathological and epidemiological relevance in children: a cohort study , 2012, BMJ Open.

[78]  P. Levendag,et al.  Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: a dose-effect relationship. , 2007, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[79]  E. Dejaeger,et al.  Dysphagia in Head and Neck Cancer Patients Treated with Chemoradiotherapy , 2010, Dysphagia.

[80]  S. Tavassoli,et al.  Eosinophilic Esophagitis in Patients with Refractory Gastroesophageal Reflux Disease , 2008, Digestive Diseases and Sciences.

[81]  Aarthi Madhavan,et al.  Dysphagia in the elderly: management and nutritional considerations , 2012, Clinical interventions in aging.

[82]  S. Aceves,et al.  Distinguishing Eosinophilic Esophagitis in Pediatric Patients: Clinical, Endoscopic, and Histologic Features of An Emerging Disorder , 2007, Journal of clinical gastroenterology.

[83]  R. Russo,et al.  Clinical characteristics of children with Juvenile Systemic Sclerosis: follow-up of 23 patients in a single tertiary center , 2007, Pediatric rheumatology online journal.

[84]  D. Buchholz,et al.  The Burke Dysphagia Screening Test: validation of its use in patients with stroke. , 1996, Dysphagia.

[85]  P. Vos,et al.  Aspiration rate following chemoradiation for head and neck cancer: an underreported occurrence. , 2006, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[86]  A. Fioritti,et al.  Choking Incidents among Psychiatric Patients: Retrospective Analysis of Thirty-one Cases from the West Bologna Psychiatric Wards , 1997, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[87]  T. Howe,et al.  Prevalence of feeding related issues/difficulties in Taiwanese children with history of prematurity, 2003-2006. , 2010, Research in developmental disabilities.

[88]  S. Cheon,et al.  Nonmotor symptoms of Parkinson's disease: prevalence and awareness of patients and families. , 2008, Parkinsonism & related disorders.

[89]  M. Yalnız,et al.  Heterotopic gastric mucosa (inlet patch): endoscopic prevalence, histopathological, demographical and clinical characteristics , 2009, International journal of clinical practice.

[90]  M. Latorre,et al.  Perioperative complications, comorbidities, and survival in oral or oropharyngeal cancer. , 2003, Archives of otolaryngology--head & neck surgery.

[91]  Yi Cui,et al.  Prevalence, clinical manifestations and endoscopic features of eosinophilic esophagitis: A pathological review in China , 2012, Journal of digestive diseases.

[92]  M. Vassallo,et al.  WHAT INFLUENCES OUTCOME OF STROKE – PYREXIA OR DYSPHAGIA? , 2001, International journal of clinical practice.

[93]  T. Nagamine.  Serum substance P levels in patients with chronic schizophrenia treated with typical or atypical antipsychotics , 2008, Neuropsychiatric disease and treatment.

[94]  M. Fehlings,et al.  Perioperative and delayed complications associated with the surgical treatment of cervical spondylotic myelopathy based on 302 patients from the AOSpine North America Cervical Spondylotic Myelopathy Study. , 2012, Journal of neurosurgery. Spine.

[95]  M. Tanrıverdi,et al.  Deep neck space infections: a retrospective review of 173 cases. , 2012, American journal of otolaryngology.

[96]  H. Bergquist,et al.  The Incidence of Esophageal Bolus Impaction , 2011, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[97]  Tomoyuki Koike,et al.  Prevalence of gastroesophageal reflux symptoms in a large unselected general population in Japan. , 2008, World journal of gastroenterology.

[98]  O. Ekberg,et al.  Quantitative assessment of oral and pharyngeal function in Parkinson's disease , 2004, Dysphagia.

[99]  D. Dawson,et al.  Swallowing in Alzheimer's Disease , 1994, Alzheimer disease and associated disorders.

[100]  D. Smithard,et al.  Complications and outcome after acute stroke. Does dysphagia matter? , 1996, Stroke.

[101]  L. Riley,et al.  Postoperative Dysphagia in Anterior Cervical Spine Surgery , 2010, Spine.

[102]  S. Hamdy,et al.  Prevalence and symptom profiling of oropharyngeal dysphagia in a community dwelling of an elderly population: a self-reporting questionnaire survey. , 2009, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[103]  M. Davila,et al.  Features of Gastroesophageal Reflux Disease in Women , 2004, American Journal of Gastroenterology.

[104]  S. Spencer,et al.  Factors associated with long-term dysphagia after definitive radiotherapy for locally advanced head-and-neck cancer. , 2009, International journal of radiation oncology, biology, physics.

[105]  R. Kaufman,et al.  Prediction of aspiration in patients with newly diagnosed untreated advanced head and neck cancer. , 2001, Archives of otolaryngology--head & neck surgery.

[106]  E. Quigley,et al.  Gastrointestinal dysfunction in Parkinson's disease , 1992, Neurology.

[107]  N. Taylor,et al.  Dysphagia is a Common and Serious Problem for Adults with Mental Illness: A Systematic Review , 2012, Dysphagia.

[108]  D. Watson,et al.  Prevalence of Symptoms and Use of Medication for Gastroesophageal Reflux in an Australian Community , 2008, World Journal of Surgery.

[109]  A. Hölscher,et al.  Prevalence of Dysphagia in Patients with Gastroesophageal Reflux in Germany , 2008, Dysphagia.

[110]  D H Barer,et al.  The natural history and functional consequences of dysphagia after hemispheric stroke. , 1989, Journal of neurology, neurosurgery, and psychiatry.

[111]  J. Robbins,et al.  Eating Changes in Mild-Stage Alzheimer's Disease: A Pilot Study , 1997, Dysphagia.

[112]  N. Theodore,et al.  Dysphagia after anterior cervical spine surgery: incidence and risk factors. , 2012, World neurosurgery.

[113]  A. Singal,et al.  Lymphocytic Esophagitis: A Diagnosis of Increasing Frequency , 2012, Journal of clinical gastroenterology.

[114]  C. Chung,et al.  Aspiration subsequent to a pure medullary infarction: lesion sites, clinical variables, and outcome. , 2000, Archives of neurology.

[115]  O. Kölbl,et al.  Dysphagia. Impact on quality of life after radio(chemo)therapy of head and neck cancer. , 2011, Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al].

[116]  L. Werneck,et al.  Cervical dystonia: clinical and therapeutic features in 85 patients. , 2008, Arquivos de neuro-psiquiatria.

[117]  A M Stiggelbout,et al.  Patient-reported autonomic symptoms in Parkinson disease , 2007, Neurology.

[118]  J. Baudet,et al.  Heterotopic gastric mucosa: A significant clinical entity , 2006, Scandinavian journal of gastroenterology.

[119]  Shunichiro Shinagawa,et al.  Characteristics of eating and swallowing problems in patients who have dementia with Lewy bodies , 2009, International Psychogeriatrics.

[120]  C. Gaelyn Garrett,et al.  Otolaryngologic presentations of amyotrophic lateral sclerosis , 2005, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[121]  G. Hankey,et al.  Swallowing function after stroke: prognosis and prognostic factors at 6 months. , 1999, Stroke.

[122]  F. Feng,et al.  Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures. , 2007, International journal of radiation oncology, biology, physics.

[123]  R. Pietrobon,et al.  Impact of surgical approach on complications and resource utilization of cervical spine fusion: a nationwide perspective to the surgical treatment of diffuse cervical spondylosis. , 2009, The spine journal : official journal of the North American Spine Society.

[124]  A. Perry,et al.  Post-Laryngectomy: It’s Hard to Swallow , 2009, Dysphagia.

[125]  M. Wallander,et al.  Esophageal Stricture: Incidence, Treatment Patterns, and Recurrence Rate , 2006, The American Journal of Gastroenterology.

[126]  B. Bloem,et al.  Prevalence of oropharyngeal dysphagia in Parkinson's disease: a meta-analysis. , 2012, Parkinsonism & related disorders.

[127]  P. Clavé,et al.  Prevalence and prognostic implications of dysphagia in elderly patients with pneumonia. , 2010, Age and ageing.

[128]  L. Jacobsson,et al.  Dysphagia and dysmotility of the pharynx and oesophagus in patients with primary Sjögren's syndrome , 2007, Scandinavian journal of rheumatology.

[129]  P. Devitt,et al.  Single center prospective randomized trial of laparoscopic Nissen versus anterior 90° fundoplication , 2006, Journal of Gastrointestinal Surgery.

[130]  R L Hewer,et al.  Motor loss and swallowing difficulty after stroke: frequency, recovery, and prognosis. , 1987, Acta neurologica Scandinavica.

[131]  D. Yang,et al.  The prevalence and patterns of pharyngoesophageal dysmotility in patients with early stage Parkinson's disease , 2010, Movement disorders : official journal of the Movement Disorder Society.

[132]  D. García-Compeán,et al.  Prevalence of eosinophilic esophagitis in patients with refractory gastroesophageal reflux disease symptoms: A prospective study. , 2011, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[133]  L. Weisberg,et al.  Aspiration in patients with acute stroke. , 1998, Archives of physical medicine and rehabilitation.

[134]  A. Féve,et al.  Laryngeal tardive dyskinesia , 1995, Journal of Neurology.

[135]  A. Bakheit,et al.  Dysphagia in Parkinson's disease. , 1997, European neurology.

[136]  S. Parikh,et al.  Otolaryngologic manifestations of mitochondrial cytopathies. , 2009, American journal of otolaryngology.

[137]  H. Nava,et al.  The changing profile of esophageal cancer presentation and its implication for diagnosis. , 2007, Journal of the National Medical Association.

[138]  W. Schäbitz,et al.  Assessment of aspiration risk in acute ischaemic stroke—evaluation of the simple swallowing provocation test , 2008, Journal of Neurology, Neurosurgery, and Psychiatry.

[139]  I. Walsh,et al.  Prevalence of Dysphagia in Acute and Community Mental Health Settings , 2006, Dysphagia.

[140]  S. Remick,et al.  Anaplastic Thyroid Cancer: A Review of Epidemiology, Pathogenesis, and Treatment , 2011, Journal of oncology.

[141]  P. Devitt,et al.  Ten‐year clinical outcome of a prospective randomized clinical trial of laparoscopic Nissen versus anterior 180° partial fundoplication , 2008, The British journal of surgery.

[142]  D. Gottlieb,et al.  Validation of the 50 ml3 drinking test for evaluation of post-stroke dysphagia. , 1996, Disability and rehabilitation.

[143]  P. Kerlin,et al.  Prevalence of Eosinophilic Esophagitis in Adults With Food Bolus Obstruction of the Esophagus , 2007, Journal of clinical gastroenterology.

[144]  D. Bragg,et al.  The effect of chlorpromazine on the swallowing function in chronic schizophrenic patients. , 1969, American Journal of Psychiatry.

[145]  D J Burn,et al.  Swallowing problems in Parkinson disease: frequency and clinical correlates , 2008, Journal of Neurology, Neurosurgery & Psychiatry.

[146]  A. Rademaker,et al.  Pretreatment swallowing function in patients with head and neck cancer , 2000, Head & neck.

[147]  J. Rothwell,et al.  Explaining oropharyngeal dysphagia after unilateral hemispheric stroke , 1997, The Lancet.

[148]  S. Y. Phua,et al.  Accuracy of Bedside Clinical Methods Compared with Fiberoptic Endoscopic Examination of Swallowing (FEES) in Determining the Risk of Aspiration in Acute Stroke Patients , 2014, Dysphagia.

[149]  S. Wong,et al.  Dysphagia in individuals with tetraplegia: incidence and risk factors , 2011, The journal of spinal cord medicine.

[150]  J R Hodges,et al.  Changes in appetite, food preference, and eating habits in frontotemporal dementia and Alzheimer’s disease , 2002, Journal of neurology, neurosurgery, and psychiatry.

[151]  R. Teasell,et al.  Clinical characteristics of patients with brainstem strokes admitted to a rehabilitation unit. , 2002, Archives of physical medicine and rehabilitation.

[152]  A. Morgan,et al.  Incidence and clinical presentation of dysarthria and dysphagia in the acute setting following paediatric traumatic brain injury. , 2010, Child: care, health and development.

[153]  S. Danesh-Sani,et al.  Clinical assessment of orofacial manifestations in 500 patients with multiple sclerosis. , 2013, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[154]  S. Langmore,et al.  Predictors of Aspiration Pneumonia: How Important Is Dysphagia? , 1998, Dysphagia.

[155]  Angelo Antonini,et al.  The PRIAMO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease , 2009, Movement disorders : official journal of the Movement Disorder Society.

[156]  R. Franco.  Acute Supraglottitis in Adults in Finland: Review and Analysis of 308 Cases , 2012 .

[157]  C. Lamb,et al.  The diagnosis of primary eosinophilic oesophagitis in adults: missed or misinterpreted? , 2010, European journal of gastroenterology & hepatology.

[158]  D. Sinha,et al.  Proximal Esophageal Stenosis in Head and Neck Cancer Patients after Total Laryngectomy and Radiation , 2008, ORL.

[159]  Kannayiram Alagiakrishnan,et al.  Evaluation and management of oropharyngeal dysphagia in different types of dementia: a systematic review. , 2013, Archives of gerontology and geriatrics.

[160]  J. Macmahon,et al.  Aspiration in acute stroke: a clinical study with videofluoroscopy. , 1993, The Quarterly journal of medicine.

[161]  I. Martin,et al.  Multicenter, prospective, double-blind, randomized trial of laparoscopic nissen vs anterior 90 degrees partial fundoplication. , 2004, Archives of surgery.

[162]  Michael J Lee,et al.  Incidence of Dysphagia After Anterior Cervical Spine Surgery: A Prospective Study , 2002, Spine.

[163]  D. Streiner,et al.  MRI-Based Neuroanatomical Predictors of Dysphagia after Acute Ischemic Stroke: A Systematic Review and Meta-Analysis , 2011, Cerebrovascular Diseases.

[164]  R. Hinder,et al.  Insights Gained from Symptom Evaluation of Esophageal Motility Disorders: A Review of 4,215 Patients , 2012, Digestion.

[165]  B. Avidan,et al.  Reflux symptoms are associated with psychiatric disease , 2001, Alimentary pharmacology & therapeutics.

[166]  W. Wong,et al.  Prevalence, clinical spectrum and health care utilization of gastro‐oesophageal reflux disease in a Chinese population: a population‐based study , 2003, Alimentary pharmacology & therapeutics.

[167]  D. Levine,et al.  Dysphagia in patients with erosive esophagitis: prevalence, severity, and response to proton pump inhibitor treatment. , 2004, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[168]  T. Warnecke,et al.  Dysphagia in patients with acute striatocapsular hemorrhage , 2011, Journal of Neurology.

[169]  C. M. Wiles,et al.  Assessment of swallowing and referral to speech and language therapists in acute stroke. , 1998, QJM : monthly journal of the Association of Physicians.

[170]  R. Pietrobon,et al.  Prospective Analysis of Incidence and Risk Factors of Dysphagia in Spine Surgery Patients: Comparison of Anterior Cervical, Posterior Cervical, and Lumbar Procedures , 2004, Spine.

[171]  P. Vos,et al.  Dysphagia severity following chemoradiation and postoperative radiation for head and neck cancer. , 2006, European journal of radiology.

[172]  R. Murison,et al.  Incidence, Characteristics, and Predictive Factors for Dysphagia After Pediatric Traumatic Brain Injury , 2003, The Journal of head trauma rehabilitation.

[173]  L. Knight,et al.  Congenital cysts of the infant larynx. , 2012, International journal of pediatric otorhinolaryngology.

[174]  M. B. Gillespie,et al.  Thyroid disease and compressive symptoms , 2012, The Laryngoscope.

[175]  Y. Rampersaud,et al.  Morbidity and mortality of major adult spinal surgery. A prospective cohort analysis of 942 consecutive patients. , 2009, The spine journal : official journal of the North American Spine Society.

[176]  Laurence Negre-Pages,et al.  Oro‐buccal symptoms (dysphagia, dysarthria, and sialorrhea) in patients with Parkinson’s disease: preliminary analysis from the French COPARK cohort , 2012, European journal of neurology.

[177]  J C Rothwell,et al.  Recovery of swallowing after dysphagic stroke relates to functional reorganization in the intact motor cortex. , 1998, Gastroenterology.

[178]  F. Mastaglia,et al.  Dysphagia in Inflammatory Myopathy: Self-report, Incidence, and Prevalence , 2012, Dysphagia.

[179]  P. Clavé,et al.  Long-term prevalence of oropharyngeal dysphagia in head and neck cancer patients: Impact on quality of life. , 2007, Clinical nutrition.

[180]  A. Morgan.  Dysphagia in childhood traumatic brain injury: A reflection on the evidence and its implications for practice , 2010, Developmental neurorehabilitation.

[181]  D. Wade,et al.  Dysphagia in acute stroke. , 1987, British medical journal.

[182]  M. Power,et al.  Awareness of Dysphagia by Patients Following Stroke Predicts Swallowing Performance , 2003, Dysphagia.

[183]  Edie R. Hapner,et al.  Prevalence of Perceived Dysphagia and Quality-of-Life Impairment in a Geriatric Population , 2007, Dysphagia.

[184]  M. Muntó,et al.  [Swallowing changes in cerebrovascular accidents: incidence, natural history, and repercussions on the nutritional status, morbidity, and mortality]. , 1998, Revista de neurologia.

[185]  N. Aaronson,et al.  Quality of life after curative radiotherapy in Stage I non-small-cell lung cancer. , 2002, International journal of radiation oncology, biology, physics.

[186]  W. Dolen,et al.  Feeding Dysfunction in Children With Eosinophilic Gastrointestinal Diseases , 2011, Pediatrics.

[187]  K. Hamberg,et al.  Symptoms and problems with functioning among women and men with inoperable lung cancer--a longitudinal study. , 2008, Lung cancer.

[188]  M. Vieth,et al.  Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: the population-based Kalixanda study , 2006, Gut.

[189]  G. Fried,et al.  Comparison of patient-centered outcomes after laparoscopic Nissen fundoplication for gastroesophageal reflux disease or paraesophageal hernia , 2008, Surgical Endoscopy.

[190]  L. Mccargar,et al.  Nutrition impact symptoms: Key determinants of reduced dietary intake, weight loss, and reduced functional capacity of patients with head and neck cancer before treatment , 2009, Head & neck.

[191]  H. Arnold,et al.  Routine screening for eosinophilic esophagitis in patients presenting with dysphagia , 2011, Therapeutic advances in gastroenterology.

[192]  P. Vos,et al.  Evolution of chronic dysphagia following treatment for head and neck cancer. , 2006, Oral oncology.

[193]  M. Raimondo,et al.  Seasonal Distribution in Newly Diagnosed Cases of Eosinophilic Esophagitis in Adults , 2009, The American Journal of Gastroenterology.