Structure and Function of Eukaryotic Chromosomes

This book presents an overview of various aspects of chromosome research, written by leading experts of the respective fields, combining classic and recent molecular biological results. The variety and comprehensiveness make it a handbook of chromosome research for all scientists, teachers and graduate students interested in this field. Dieses Buch fasst die unterschiedlichen Aspekte der Chromosomenforschung in Beitragen von fuhrenden Wissenschaftlern zusammen, wobei die klassischen Erkenntnisse mit neuesten Forschungsdaten zu einem umfassenden Uberblick uber das Gebiet kombiniert werden."

[1]  O. Miller,et al.  The 5′→3′ polarity of the xenopus ribosomal RNA precursor molecule , 1976, Cell.

[2]  P. Vogt,et al.  Identification of cloned Y chromosomal DNA sequences from a lampbrush loop of Drosophila hydei. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[3]  D. Hultmark,et al.  Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22 , 1986, Cell.

[4]  T. Mohandas,et al.  Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. , 1981, Science.

[5]  T. Kinsella,et al.  Bromodeoxyuridine in tumors and chromosomes detected with a monoclonal antibody. , 1983, The Journal of clinical investigation.

[6]  R. D. Carlson,et al.  OF CHROMATIN SUBSTRUCTURE: t)BODIES , 1975 .

[7]  L. Goldstein,et al.  Structural genes on the Y chromosome of Drosophila melanogaster. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[8]  A. Hsie,et al.  v-Bodies in mitotic chromatin , 1976 .

[9]  W. Hennig.  Ribonucleic acid synthesis of the Y-chromosome of Drosophila hydei. , 1968, Journal of molecular biology.

[10]  J. Sogo,et al.  Chromatin structure of a hyperactive secretory protein gene (in Balbiani ring 2) of Chironomus. , 1984, The EMBO journal.

[11]  S. Beermann.  A Quantitative Study of Chromatin Diminution in Embryonic Mitoses of CYCLOPS FURCIFER. , 1966, Genetics.

[12]  J. H. Taylor,et al.  Asynchronous Duplication of Chromosomes in Cultured Cells of Chinese Hamster , 2003 .

[13]  G. Felsenfeld,et al.  Nucleosome structure. , 1980, Annual review of biochemistry.

[14]  S. McKnight,et al.  Electron microscopic analysis of chromosome metabolism in the Drosophila melanogaster embryo. , 1978, Cold Spring Harbor symposia on quantitative biology.

[15]  Donald D. Brown.  The role of stable complexes that repress and activate eucaryotic genes , 1984, Cell.

[16]  D. E. Olins,et al.  Spheroid chromatin units (v bodies). , 1974, Science.

[17]  G. Clawson,et al.  Nuclear envelope structure and RNA maturation , 1985 .

[18]  H. Spring,et al.  Morphology of transcriptional units of rDNA. Evidence for transcription in apparent spacer intercepts and cleavages in the elongating nascent RNA. , 1976, Experimental cell research.

[19]  M. Lalande,et al.  High resolution analysis of the timing of replication of specific DNA sequences during S phase of mammalian cells. , 1983, Nucleic acids research.

[20]  P. Labhart,et al.  Involvement of higher order chromatin structures in metaphase chromosome organization , 1982, Cell.

[21]  W. Franke,et al.  Morphology of transcriptional units at different states of activity. , 1978, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[22]  Joseph Gall.  Chromosome Fibers from an Interphase Nucleus , 1963, Science.

[23]  H. Spring,et al.  Transcriptionally active chromatin in loops of lampbrush chromosomes at physiological salt concentrations as revealed by electron microscopy of sections. , 1981, European journal of cell biology.

[24]  M. Botchan,et al.  Characterization of the Bovine Papilloma virus plasmid maintenance sequences , 1984, Cell.

[25]  Y. Osheim,et al.  Novel amplification and transcriptional activity of chorion genes in Drosophila melanogaster follicle cells , 1983, Cell.

[26]  U. Scheer.  Changes of nucleosome frequency in nucleolar and non-nucleolar chromatin as a function of transcription: an electron microscopic study , 1978, Cell.

[27]  L. Deaven,et al.  Synchronized mammalian cell cultures. I. Cell replication cycle and macromolecular synthesis following brief colcemid arrest of mitosis , 1967, Journal of cellular physiology.

[28]  C. Bridges.  Non-Disjunction as Proof of the Chromosome Theory of Heredity. , 2019, Genetics.

[29]  J. M. Collins.  Rates of DNA synthesis during the S-phase of HeLa cells. , 1978, The Journal of biological chemistry.

[30]  E. Craig,et al.  The heat shock response. , 1985, CRC critical reviews in biochemistry.

[31]  H. Ris,et al.  6 – Chromosome Structure and Levels of Chromosome Organization , 1979 .

[32]  P. Vogt,et al.  Y chromosomal DNA of Drosophila hydei. , 1983, Journal of molecular biology.

[33]  G. F. Meyer,et al.  CHROMOSOMAL DIFFERENTIATIONS OF THE LAMPBRUSH TYPE FORMED BY THE Y CHROMOSOME IN DROSOPHILA HYDEI AND DROSOPHILA NEOHYDEI , 1963, The Journal of cell biology.

[34]  G. F. Meyer,et al.  Genetic activities of the Y chromosome in Drosophila during spermatogenesis. , 1968, Advances in genetics.

[35]  K. Livak.  Organization and mapping of a sequence on the Drosophila melanogaster X and Y chromosomes that is transcribed during spermatogenesis. , 1984, Genetics.

[36]  O. Miller,et al.  Extrachromosomal nucleolar genes in amphibian oocytes. , 1969, Genetics.

[37]  R. Hill.  A quantitative electron-microscope analysis of chromatin from Xenopus laevis lampbrush chromosomes. , 1979, Journal of cell science.

[38]  B. Hamkalo,et al.  Higher Order Structure in Chromosomes , 1981 .

[39]  James M. Roberts,et al.  Negative control of DNA replication in composite SV40-bovine papilloma virus plasmids , 1986, Cell.

[40]  Robert Tjian,et al.  Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro , 1985, Cell.

[41]  M. Lyon.  Gene Action in the X-chromosome of the Mouse (Mus musculus L.) , 1961, Nature.

[42]  W. Jelinek,et al.  Replication of a plasmid bearing a human Alu-family repeat in monkey COS-7 cells. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[43]  T. Cech,et al.  Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo. , 1980, Journal of molecular biology.

[44]  H. Spring,et al.  Homogeneity and heterogeneity of sizes of transcriptional units and spacer regions in nucleolar genes of acetabularia , 1976 .

[45]  H. Zentgraf,et al.  Supranucleosomal organization of sea urchin sperm chromatin in regularly arranged 40 to 50 nm large granular subunits. , 1980, European Journal of Cell Biology.

[46]  R. Axel,et al.  Integration, transcription, and control of a Drosophila heat shock gene in mouse cells. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[47]  E. Lifschytz.  A procedure for the cloning and identification of Y-specific middle repetitive sequences in Drosophila hydei. , 1979, Journal of molecular biology.

[48]  W. Hennig,et al.  Structure and function of the Y chromosome of Drosophila hydei. , 1974, Cold Spring Harbor symposia on quantitative biology.

[49]  D. Ballinger,et al.  3 – Mechanism of Translational Control in Heat-Shocked Drosophila Cells , 1985 .

[50]  W. Hennig,et al.  MOLECULAR ASPECTS OF THE FERTILITY FACTORS IN DROSOPHILA , 1975 .

[51]  R. Greimers,et al.  Organization of transcribed and nontranscribed chromatin in isolated nuclei of Zea mays root cells. , 1981, European journal of cell biology.

[52]  C. Schildkraut,et al.  alpha-Globulin sequences are located in a region of early-replicating DNA in murine erythroleukemia cells. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[53]  W. Bernhard,et al.  Visualization of two different types of nuclear transcriptional complexes in rat liver cells. , 1977, Journal of ultrastructure research.

[54]  U. Scheer,et al.  Sizes of chromosome loops and hnRNA molecules in oocytes of amphibia of different genome sizes. , 1982, Experimental cell research.

[55]  J. Taylor.  Sister Chromatid Exchanges in Tritium-Labeled Chromosomes. , 1958, Genetics.

[56]  M. Bustin,et al.  Chromatin structure visualization by immunoelectron microscopy , 1976, Cell.

[57]  C. Schildkraut,et al.  Changes in gene position are accompanied by a change in time of replication , 1984, Cell.

[58]  R. Kornberg,et al.  Structure of chromatin. , 1977, Annual review of biochemistry.

[59]  H. G. Callan.  Review Lecture - Replication of DNA in the chromosomes of eukaryotes , 1972, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[60]  Y. Osheim,et al.  RNP particles at splice junction sequences on Drosophila chorion transcripts , 1985, Cell.

[61]  M. Ashburner,et al.  The induction of gene activity in drosophila by heat shock , 1979, Cell.

[62]  J. Koninkx.  Protein synthesis in salivary glands of Drosophila hydei after experimental gene induction. , 1976, The Biochemical journal.

[63]  M. Diaz,et al.  Transcripts from both strands of a satellite DNA occur on lampbrush chromosome loops of the newt notophthalmus , 1981, Cell.

[64]  W. Y. Chooi.  RNA Transcription and Ribosomal Protein Assembly in Drosophila melanogaster , 1976 .

[65]  W. Burhans,et al.  Isolation of the origin of replication associated with the amplified Chinese hamster dihydrofolate reductase domain. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[66]  O. Miller,et al.  Correlation of hnRNP structure and nascent transcript cleavage , 1981, Cell.

[67]  B. Childs,et al.  DEMONSTRATION OF TWO POPULATIONS OF CELLS IN THE HUMAN FEMALE HETEROZYGOUS FOR GLUCOSE-6-PHOSPHATE DEHYDROGENASE VARIANTS. , 1963, Proceedings of the National Academy of Sciences of the United States of America.

[68]  M. Bustin,et al.  Injected histone antibodies interfere with transcription of lampbrush chromosome loops in oocytes of Pleurodeles. , 1979, Journal of cell science.

[69]  S. Henikoff,et al.  Localization of RNA from heat-induced polysomes at puff sites in Drosophila melanogaster. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[70]  R. Reeder,et al.  Transcription in cloned spacers of Xenopus laevis ribosomal DNA. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[71]  C. Cantor,et al.  Reversible changes in nucleosome structure and histone H3 accessibility in transcriptionally active and inactive states of rDNA chromatin , 1983, Cell.

[72]  U. Scheer.  Structural organization of spacer chromatin between transcribed ribosomal RNA genes in amphibian oocytes. , 1980, European journal of cell biology.

[73]  H. Zentgraf,et al.  Evidence for the Existence of Globular Units in the Supranucleosomal Organization of Chromatin , 1981 .

[74]  J. Hackstein,et al.  Lampbrush loop-specific protein of Drosophila hydei. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[75]  Susan Lindquist,et al.  Regulation of protein synthesis during heat shock , 1981, Nature.

[76]  R. Morimoto,et al.  Sequence homologies in the 5' regions of four Drosophila heat-shock genes. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[77]  V. Foe,et al.  Comparative organization of active transcription units in Oncopeltus fasciatus , 1976, Cell.

[78]  H. Zentgraf,et al.  Morphology of transcriptionally active chromatin. , 1978, Cold Spring Harbor symposia on quantitative biology.

[79]  J. Calvet,et al.  Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[80]  M. Botchan,et al.  Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors , 1985, Journal of virology.

[81]  J. Priest,et al.  Reversal of DNA methylation with 5-azacytidine alters chromosome replication patterns in human lymphocyte and fibroblast cultures. , 1984, American journal of human genetics.

[82]  M Meselson,et al.  Interspecific nucleotide sequence comparisons used to identify regulatory and structural features of the Drosophila hsp82 gene. , 1986, Journal of molecular biology.

[83]  J. Davie,et al.  Ultrastructural organization of yeast chromatin , 1982, The Journal of cell biology.

[84]  A. Lima-de-faria,et al.  Late DNA Synthesis in Heterochromatin , 1968, Nature.

[85]  F. Peters.  Genomic organization of heat shock locus 2-48B of Drosophila hydei , 1983 .

[86]  D. Hémon,et al.  Mechanisms of transcription in nucleoli of amphibian oocytes as visualized by high-resolution autoradiography , 1979, The Journal of cell biology.

[87]  V. Foe.  Modulation of ribosomal RNA synthesis in Oncopeltus fasciatus: an electron microscopic study of the relationship between changes in chromatin structure and transcriptional activity. , 1978, Cold Spring Harbor symposia on quantitative biology.

[88]  K. Leiby,et al.  An electron microscopic method for localization of ribosomal proteins during transcription of ribosomal DNA: a method for studying protein assembly. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[89]  D. Villard,et al.  Visualisation des complexes de transcription dans la chromatine étalée de cellules de mammifères: étude en autoradiographie à haute résolution. , 1978 .

[90]  G. Rubin,et al.  Effect of heat shock on the synthesis of low molecular weight RNAs in drosophila: Accumulation of a novel form of 5S RNA , 1975, Cell.

[91]  K. Gross,et al.  Localization of histone gene transcripts in newt lampbrush chromosomes by in situ hybridization. , 1977, Journal of cell science.

[92]  David B. Walden,et al.  Changes in Eukaryotic Gene Expression in Response to Environmental Stress , 1985 .

[93]  U. Scheer.  Injection of antibodies into the nucleus of amphibian oocytes: an experimental means of interfering with gene expression in the living cell. , 1986, Journal of embryology and experimental morphology.

[94]  A. Bakken,et al.  Morphological studies of transcription. , 1972, Acta endocrinologica. Supplementum.

[95]  A. Spradling,et al.  Analysis of drosophila mRNA by in situ hybridization: Sequences transcribed in normal and heat shocked cultured cells , 1975, Cell.

[96]  F. Harper,et al.  Localization of T‐antigen on simian virus 40 minichromosomes by immunoelectron microscopy. , 1984, EMBO Journal.

[97]  M. Dabauvalle,et al.  Functional organization of the amphibian oocyte nucleus. , 1985, Developmental biology.

[98]  M. A. Goldman,et al.  Replication timing of genes and middle repetitive sequences. , 1984, Science.

[99]  F. Puvion-Dutilleul,et al.  Morphology of transcription at cellular and molecular levels. , 1983, International review of cytology.

[100]  M. Trendelenburg,et al.  Transcriptionally active and inactive regions of nucleolar chromatin in amplified nucleoli of fully grown oocytes of hibernating frogs, Rana pipiens (Amphibia, Anura). A quantitative electron microscopic study. , 1979, Differentiation; research in biological diversity.

[101]  W. Hennig.  Y chromosome function and spermatogenesis in Drosophila hydei. , 1985, Advances in genetics.

[102]  M. Méchali,et al.  Lack of specific sequence requirement for DNA replication in Xenopus eggs compared with high sequence specificity in yeast , 1984, Cell.

[103]  L. J. Korn.  Transcription of Xenopus 5S ribosomal RNA genes , 1982, Nature.

[104]  R. Reeder,et al.  Effect of topological constraint on transcription of ribosomal DNA in Xenopus oocytes. Comparison of plasmid and endogenous genes. , 1984, Journal of molecular biology.

[105]  H. Macgregor,et al.  The development of lampbrush chromosome-type transcription in the early diplotene oocytes of Xenopus laevis: an electron-microscope analysis. , 1980, Journal of cell science.

[106]  A. Mirzabekov,et al.  Chromatin structure of hsp 70 genes, activated by heat shock: Selective removal of histones from the coding region and their absence from the 5′ region , 1984, Cell.

[107]  F. Baas,et al.  Chromosomal localization of a unique gene by non-autoradiographic in situ hybridization , 1985, Nature.

[108]  T. Cech,et al.  Chromatin structure at the replication origins and transcription-initiation regions of the ribosomal RNA genes of tetrahymena , 1984, Cell.

[109]  B. Hamkalo,et al.  Electronmicroscopy of genetic activity. , 1973, Annual review of biochemistry.

[110]  A. J. Petersen.  DNA SYNTHESIS AND CHROMOSOMAL ASYNCHRONY , 1964, The Journal of cell biology.

[111]  B. Hamkalo,et al.  Ultrastructure of active eukaryotic genomes. , 1974, Cold Spring Harbor symposia on quantitative biology.

[112]  L. Tres,et al.  Structural and transcriptional features of the mouse spermatid genome , 1975, The Journal of cell biology.

[113]  J. H. Taylor,et al.  One role for DNA methylation in vertebrate cells is strand discrimination in mismatch repair. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[114]  W. Hennig,et al.  Lampbrush chromosome loop‐specificity of transcript morphology in spermatocyte nuclei of Drosophila hydei , 1984, The EMBO journal.

[115]  Professor Dr. Harold Garnet Callan.  Lampbrush Chromosomes , 1986, Molecular Biology, Biochemistry and Biophysics.

[116]  J. Hozier.  Chapter VII – Nucleosomes and Higher Levels of Chromosomal Organization , 1979 .

[117]  M. Pardue,et al.  A Drosophila heat shock locus with a rapidly diverging sequence but a conserved structure. , 1986, The Journal of biological chemistry.

[118]  M. Soyer,et al.  Distinctive features of dinoflagellate chromatin. Absence of nucleosomes in a primitive species Prorocentrum micans E. , 1981, European journal of cell biology.

[119]  W. Beermann.  Nuclear differentiation and functional morphology of chromosomes. , 1956, Cold Spring Harbor symposia on quantitative biology.

[120]  H. Zentgraf,et al.  Reversible in vitro packing of nucleosomal filaments into globular supranucleosomal units in chromatin of whole chick erythrocyte nuclei. , 1980, European journal of cell biology.

[121]  J. Hackstein,et al.  Genetic fine structure of the Y chromosome of Drosophila hydei. , 1982, Genetics.

[122]  J. H. Taylor,et al.  THE ORGANIZATION AND DUPLICATION OF CHROMOSOMES AS REVEALED BY AUTORADIOGRAPHIC STUDIES USING TRITIUM-LABELED THYMIDINEE. , 1957, Proceedings of the National Academy of Sciences of the United States of America.

[123]  B. Migeon,et al.  Complete reactivation of X chromosomes from human chorionic villi with a switch to early DNA replication. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[124]  P. Chambon,et al.  Electron microscopic and biochemical evidence that chromatin structure is a repeating unit , 1975, Cell.

[125]  S. McKnight,et al.  Ribonucleoprotein structure in nascent hnRNA is nonrandom and sequence-dependent , 1980, Cell.

[126]  J. Engberg.  The ribosomal RNA genes of Tetrahymena: structure and function. , 1985, European journal of cell biology.

[127]  F. Harper,et al.  Non-nucleolar transcription complexes of rat liver as revealed by spreading isolated nuclei. , 1979, Journal of cell science.

[128]  G. Pierron,et al.  Invariant temporal order of replication of the four actin gene loci during the naturally synchronous mitotic cycles of Physarum polycephalum. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[129]  E. Lifschytz,et al.  DNA clones and RNA transcripts of four lampbrush loops from the Y chromosome of Drosophila hydei , 1983, Cell.

[130]  M. Pardue,et al.  Heat shock locus 93D of Drosophila melanogaster: a spliced RNA most strongly conserved in the intron sequence. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[131]  O. Westergaard,et al.  Nuclease-sensitive regions on the extrachromosomal r-chromatin from Tetrahymena pyriformis. , 1981, European journal of biochemistry.

[132]  E. J. Dupraw.  DNA and chromosomes , 1970 .

[133]  M. Frasch,et al.  Nonpackaging and packaging proteins of hnRNA in Drosophila melanogaster , 1983, Cell.

[134]  M. Schlissel,et al.  A positive transcription factor controls the differential expression of two 5S RNA genes , 1985, Cell.

[135]  S. Lindquist,et al.  RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis , 1986, Cell.

[136]  J. Hackstein,et al.  Involvement of Y chromosomal loci in the synthesis of Drosophila hydei sperm proteins. , 1983, Developmental biology.

[137]  N. Maizels,et al.  Dictyostelium ribosomal RNA is processed during transcription , 1980, Cell.

[138]  S. Hiraga,et al.  In vitro replication of recombinant plasmids carrying chromosomal segments of Xenopus laevis. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[139]  S. Wolff,et al.  New Giemsa method for the differential staining of sister chromatids , 1974, Nature.

[140]  W. Franke,et al.  Regulation of transcription of genes of ribosomal rna during amphibian oogenesis. A biochemical and morphological study , 1976, The Journal of cell biology.

[141]  J. Sommerville.  1 – Immunolocalization and Structural Organization of Nascent RNP , 1981 .

[142]  K. H. Glätzer.  Regular substructures within homologous transcripts of spread Drosophila germ cells. , 1980, Experimental cell research.