Effects of Altering the Time of Administration and the Time Frame of Quality of life Assessments in Clinical Trials: An Example Using the EORTC QLQ-C30 in a Large Anti-Emetic Trial

[1]  F. Shepherd,et al.  Dexamethasone improves the efficacy of granisetron in the first 24 h following high-dose cisplatin chemotherapy , 1995, Supportive Care in Cancer.

[2]  M. Aapro.  Methodological issues in antiemetic studies , 1993, Investigational New Drugs.

[3]  J. Hainsworth,et al.  Phase III double-blind comparison of dolasetron mesylate and ondansetron and an evaluation of the additive role of dexamethasone in the prevention of acute and delayed nausea and vomiting due to moderately emetogenic chemotherapy. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[4]  D. Osoba,et al.  Effect of postchemotherapy nausea and vomiting on health-related quality of life , 1997, Supportive Care in Cancer.

[5]  J. Hainsworth,et al.  The role of the 5-HT3 antagonists ondansetron and dolasetron in the control of delayed onset nausea and vomiting in patients receiving moderately emetogenic chemotherapy. , 1997, Annals of oncology : official journal of the European Society for Medical Oncology.

[6]  D. Osoba,et al.  Determinants of postchemotherapy nausea and vomiting in patients with cancer. Quality of Life and Symptom Control Committees of the National Cancer Institute of Canada Clinical Trials Group. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[7]  D. Osoba,et al.  Quality of life studies in chemotherapy-induced emesis. , 1996, Oncology.

[8]  Andrew Bottomley,et al.  EORTC QLQ-C30 Scoring Manual , 1995 .

[9]  D. Osoba,et al.  The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. , 1993, Journal of the National Cancer Institute.

[10]  M. Tonato,et al.  Methodology of antiemetic trials: a review. , 1991, Annals of oncology : official journal of the European Society for Medical Oncology.