Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway

[1]  M. Delgado-Rodríguez,et al.  Systematic review and meta-analysis. , 2017, Medicina intensiva.

[2]  Miaojian Wan,et al.  β-Catenin is involved in oleanolic acid-dependent promotion of proliferation in human hair matrix cells in an in vitro organ culture model. , 2017, Fitoterapia.

[3]  Marshall Godwin,et al.  The effectiveness of treatments for androgenetic alopecia: A systematic review and meta‐analysis , 2017, Journal of the American Academy of Dermatology.

[4]  S. Arase,et al.  Novel ALK5 inhibitor TP0427736 reduces TGF-β induced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles. , 2017 .

[5]  S. Arase,et al.  Novel ALK5 inhibitor TP0427736 reduces TGF-β induced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles , 2017, Pharmacological reports : PR.

[6]  M. Halász,et al.  Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process , 2017, Clinical, cosmetic and investigational dermatology.

[7]  Guangyu Li,et al.  Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling , 2016, Cellular Physiology and Biochemistry.

[8]  M. Kwack,et al.  15-deoxy prostaglandin J2, the nonenzymatic metabolite of prostaglandin D2, induces apoptosis in keratinocytes of human hair follicles: a possible explanation for prostaglandin D2-mediated inhibition of hair growth , 2016, Naunyn-Schmiedeberg's Archives of Pharmacology.

[9]  M. Kwack,et al.  15-deoxy prostaglandin J2, the nonenzymatic metabolite of prostaglandin D2, induces apoptosis in keratinocytes of human hair follicles: a possible explanation for prostaglandin D2-mediated inhibition of hair growth , 2016, Naunyn-Schmiedeberg's Archives of Pharmacology.

[10]  Xuegang Li,et al.  The Hypoglycemic and Synergistic Effect of Loganin, Morroniside, and Ursolic Acid Isolated from the Fruits of Cornus officinalis , 2016, Phytotherapy research : PTR.

[11]  S. Su,et al.  Simultaneous determination of loganin, morroniside, catalpol and acteoside in normal and chronic kidney disease rat plasma by UPLC-MS for investigating the pharmacokinetics of Rehmannia glutinosa and Cornus officinalis Sieb drug pair extract. , 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[12]  P. Fong,et al.  In silico prediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss. , 2015, Journal of ethnopharmacology.

[13]  John H. E. Nash,et al.  Evaluation by microarray of the potential safety of Sarracenia purpurea L. (Sarraceniaceae) a traditional medicine used by the Cree of Eeyou Istchee. , 2015, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

[14]  K. Morishita,et al.  L-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo. , 2015, Journal of pharmacological sciences.

[15]  M. Herbin,et al.  Presence of plicidentine in the oral teeth of the coelacanth Latimeria chalumnae Smith 1939 (Sarcopterygii; Actinistia). , 2015, Journal of structural biology.

[16]  Michael R Hamblin,et al.  Drug discovery for alopecia: gone today, hair tomorrow , 2015, Expert opinion on drug discovery.

[17]  Li Zhang,et al.  Promoting neurogenesis via Wnt/β-catenin signaling pathway accounts for the neurorestorative effects of morroniside against cerebral ischemia injury. , 2014, European journal of pharmacology.

[18]  A. López-García,et al.  IL-6 as a corneal wound healing mediator in an in vitro scratch assay. , 2014, Experimental eye research.

[19]  S. Cai,et al.  Expression of decorin throughout the murine hair follicle cycle: hair cycle dependence and anagen phase prolongation , 2014, Experimental dermatology.

[20]  Heon-Sub Shin,et al.  Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model. , 2014, Biological & pharmaceutical bulletin.

[21]  M. Zheng,et al.  VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro. , 2014, Journal of dermatological science.

[22]  A. Jenkins,et al.  Elevated Circulation Levels of an Anti-angiogenic SERPIN in Patients with Diabetic Microvascular Complications Impairs Wound Healing through Suppression of Wnt Signaling , 2014, The Journal of investigative dermatology.

[23]  O. Kwon,et al.  Valproic acid promotes human hair growth in in vitro culture model. , 2013, Journal of dermatological science.

[24]  Wei Li,et al.  Morroniside promotes bone marrow mesenchymal stem cell proliferation in rats. , 2013, Molecular medicine reports.

[25]  R. Atit,et al.  Epithelial Wnt ligand secretion is required for adult hair follicle growth and regeneration , 2012, The Journal of investigative dermatology.

[26]  Chun-ming Li,et al.  VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway , 2012, Molecular Biology Reports.

[27]  M. Kim,et al.  Dickkopf 1 promotes regression of hair follicles. , 2012, The Journal of investigative dermatology.

[28]  R. Atit,et al.  Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation , 2012, Development.

[29]  B. Dong,et al.  Establishment and characterization of outer root sheath (ORS) cell line from Jining grey goat , 2012, Biotechnology Letters.

[30]  Piul S. Rabbani,et al.  Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration , 2011, Cell.

[31]  Jian-xing Ma,et al.  Wnt pathway antagonists and angiogenesis , 2010, Protein & Cell.

[32]  Xi-jun Wang,et al.  The Pharmacological Effects of Morroniside and Loganin Isolated from Liuweidihuang Wan, on MC3T3-E1 Cells , 2010, Molecules.

[33]  B. Morgan,et al.  beta-catenin activity in the dermal papilla regulates morphogenesis and regeneration of hair. , 2010, Developmental cell.

[34]  R. Nusse,et al.  Towards an integrated view of Wnt signaling in development , 2009, Development.

[35]  C. Higgins,et al.  From telogen to exogen: mechanisms underlying formation and subsequent loss of the hair club fiber. , 2009, The Journal of investigative dermatology.

[36]  R. Paus,et al.  Human hair follicle epithelium has an antimicrobial defence system that includes the inducible antimicrobial peptide psoriasin (S100A7) and RNase 7 , 2009, The British journal of dermatology.

[37]  H. Pasolli,et al.  A two-step mechanism for stem cell activation during hair regeneration. , 2009, Cell stem cell.

[38]  P. Arck,et al.  Burden of hair loss: stress and the underestimated psychosocial impact of telogen effluvium and androgenetic alopecia. , 2004, The Journal of investigative dermatology.

[39]  Hai-Ping Hao,et al.  Morroniside protects cultured human umbilical vein endothelial cells from damage by high ambient glucose. , 2004, Acta pharmacologica Sinica.

[40]  R Paus,et al.  A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. , 2001, The Journal of investigative dermatology.

[41]  W. Birchmeier,et al.  β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin , 2001, Cell.

[42]  R Paus,et al.  The biology of hair follicles. , 1999, The New England journal of medicine.

[43]  E. Fuchs,et al.  Manipulation of outer root sheath cell survival perturbs the hair‐growth cycle , 1999, The EMBO journal.

[44]  Qi Wang,et al.  Morroniside-Induced PP2A Activation Antagonizes Tau Hyperphosphorylation in a Cellular Model of Neurodegeneration. , 2016, Journal of Alzheimer's disease : JAD.

[45]  Ke Yang,et al.  Adenovirus-mediated Wnt10b overexpression induces hair follicle regeneration. , 2013, The Journal of investigative dermatology.

[46]  Gone Today.  Gone Today...Hair Tomorrow? , 2004, Lab Animal.