Forskolin and IBMX Induce Neural Transdifferentiation of MSCs Through Downregulation of the NRSF

[1]  Jing Liang,et al.  Chromatin architecture reorganization during stem cell differentiation , 2015, Nature.

[2]  Li Liu,et al.  CREB modulates calcium signaling in cAMP-induced bone marrow stromal cells (BMSCs). , 2014, Cell calcium.

[3]  B. Ren,et al.  The 3D genome in transcriptional regulation and pluripotency. , 2014, Cell stem cell.

[4]  Kwang-Soo Kim,et al.  Functional roles of Nurr1, Pitx3, and Lmx1a in neurogenesis and phenotype specification of dopamine neurons during in vitro differentiation of embryonic stem cells. , 2014, Stem cells and development.

[5]  K. Hochedlinger,et al.  Chromatin dynamics during cellular reprogramming , 2013, Nature.

[6]  M. S. Farhan,et al.  Short‐term evaluation of autologous transplantation of bone marrow–derived mesenchymal stem cells in patients with cirrhosis: Egyptian study , 2013, Clinical transplantation.

[7]  T. Florio,et al.  Tryptophan hydroxylase 2 (TPH2) in a neuronal cell line: modulation by cell differentiation and NRSF/rest activity , 2012, Journal of neurochemistry.

[8]  Maria Teresa Dell'Anno,et al.  Direct generation of functional dopaminergic neurons from mouse and human fibroblasts , 2011, Nature.

[9]  Li Liu,et al.  cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells , 2011, Cellular and Molecular Life Sciences.

[10]  Q. Han,et al.  Not a process of simple vicariousness, the differentiation of human adipose-derived mesenchymal stem cells to renal tubular epithelial cells plays an important role in acute kidney injury repairing. , 2010, Stem cells and development.

[11]  H. Okano,et al.  BMP-induced REST regulates the establishment and maintenance of astrocytic identity , 2010, The Journal of cell biology.

[12]  S. Totey,et al.  Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stem cell transplantation in Parkinson's disease. , 2010, Translational research : the journal of laboratory and clinical medicine.

[13]  S. Phadnis,et al.  Generation of Pancreatic Hormone‐Expressing Islet‐Like Cell Aggregates from Murine Adipose Tissue‐Derived Stem Cells , 2009, Stem cells.

[14]  M. Calcagnotto,et al.  Chemically-Induced RAT Mesenchymal Stem Cells Adopt Molecular Properties of Neuronal-Like Cells but Do Not Have Basic Neuronal Functional Properties , 2009, PloS one.

[15]  M. Tomishima,et al.  Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling , 2009, Nature Biotechnology.

[16]  A. Sbarbati,et al.  Neuronal differentiation potential of human adipose-derived mesenchymal stem cells. , 2008, Stem cells and development.

[17]  Lin Chen,et al.  NRSF silencing induces neuronal differentiation of human mesenchymal stem cells. , 2008, Experimental cell research.

[18]  E. Melamed,et al.  Induction of human mesenchymal stem cells into dopamine-producing cells with different differentiation protocols. , 2008, Stem cells and development.

[19]  Yang Shi,et al.  SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation , 2008, Nature.

[20]  M. MacDonald,et al.  Widespread Disruption of Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy at Its Target Genes in Huntington's Disease , 2007, The Journal of Neuroscience.

[21]  A. Sbarbati,et al.  Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus. , 2007, Bone.

[22]  A. Benabid,et al.  Functional Neuronal Differentiation of Bone Marrow‐Derived Mesenchymal Stem Cells , 2006, Stem cells.

[23]  A. Vercelli,et al.  Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types. , 2006, Experimental hematology.

[24]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[25]  Seung-Up Kim,et al.  Regulation of human tyrosine hydroxylase gene by neuron-restrictive silencer factor. , 2006, Biochemical and biophysical research communications.

[26]  J. Massagué,et al.  Smad transcription factors. , 2005, Genes & development.

[27]  J. Zimmer,et al.  Neural transdifferentiation of mesenchymal stem cells – a critical review , 2005, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[28]  J. Coulson Transcriptional Regulation: Cancer, Neurons and the REST , 2005, Current Biology.

[29]  G. Mandel,et al.  REST and Its Corepressors Mediate Plasticity of Neuronal Gene Chromatin throughout Neurogenesis , 2005, Cell.

[30]  L. Altucci,et al.  Molecular pathways involved in neural in vitro differentiation of marrow stromal stem cells , 2005, Journal of cellular biochemistry.

[31]  G. Moonen,et al.  Plasticity of Cultured Mesenchymal Stem Cells: Switch from Nestin‐Positive to Excitable Neuron‐Like Phenotype , 2005, Stem cells.

[32]  O. Lee,et al.  In vitro hepatic differentiation of human mesenchymal stem cells , 2004, Hepatology.

[33]  S. Kameoka,et al.  Activation of REST/NRSF Target Genes in Neural Stem Cells Is Sufficient To Cause Neuronal Differentiation , 2004, Molecular and Cellular Biology.

[34]  L. Lagneaux,et al.  Bone marrow-derived mesenchymal stem cells already express specific neural proteins before any differentiation. , 2004, Differentiation; research in biological diversity.

[35]  M. Tuszynski,et al.  Induction of bone marrow stromal cells to neurons: Differentiation, transdifferentiation, or artifact? , 2004, Journal of neuroscience research.

[36]  E. D. De Robertis,et al.  Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. , 2003, Genes & development.

[37]  T. Ogura,et al.  The canonical Wnt pathway directly regulates NRSF/REST expression in chick spinal cord. , 2003, Biochemical and biophysical research communications.

[38]  Andrea Crotti,et al.  Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes , 2003, Nature Genetics.

[39]  Min Zhu,et al.  Human adipose tissue is a source of multipotent stem cells. , 2002, Molecular biology of the cell.

[40]  Ali H. Brivanlou,et al.  Neural induction, the default model and embryonic stem cells , 2002, Nature Reviews Neuroscience.

[41]  H. Lorenz,et al.  Multilineage cells from human adipose tissue: implications for cell-based therapies. , 2001, Tissue engineering.

[42]  I. Fischer,et al.  In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. , 2001, Biochemical and biophysical research communications.

[43]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[44]  S. Ogawa,et al.  Cardiomyocytes can be generated from marrow stromal cells in vitro. , 1999, The Journal of clinical investigation.

[45]  H. Weintraub,et al.  Expression of a single transfected cDNA converts fibroblasts to myoblasts , 1987, Cell.