Integrated stress response activation by sleep fragmentation during late gestation in mice leads to emergence of adverse metabolic phenotype in offspring.

[1]  R. Simmons,et al.  Maternal obesity and prenatal programming , 2016, Molecular and Cellular Endocrinology.

[2]  L. Kheirandish-Gozal,et al.  Circulating Plasma Extracellular Microvesicle MicroRNA Cargo and Endothelial Dysfunction in Children with Obstructive Sleep Apnea. , 2016, American journal of respiratory and critical care medicine.

[3]  R. Farré,et al.  Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation , 2016, Oncotarget.

[4]  G. Burton,et al.  Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants , 2016, Diabetologia.

[5]  J. Edgar.  Q&A: What are exosomes, exactly? , 2016, BMC Biology.

[6]  J. Prins,et al.  Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes. , 2016, Journal of molecular endocrinology.

[7]  S. Ozanne,et al.  The early origins of obesity and insulin resistance: timing, programming and mechanisms , 2016, International Journal of Obesity.

[8]  D. Neureiter,et al.  Endoplasmic Reticulum Stress in Pancreatic Neuroendocrine Tumors is Linked to Clinicopathological Parameters and Possible Epigenetic Regulations. , 2015, Anticancer research.

[9]  K. Isobe,et al.  GADD34-deficient mice develop obesity, nonalcoholic fatty liver disease, hepatic carcinoma and insulin resistance , 2015, Scientific Reports.

[10]  D. Gozal,et al.  Epigenomic profiling in visceral white adipose tissue of offspring of mice exposed to late gestational sleep fragmentation , 2015, International Journal of Obesity.

[11]  M. Nóbrega,et al.  Early-life physical activity reverses metabolic and Foxo1 epigenetic misregulation induced by gestational sleep disturbance. , 2015, American journal of physiology. Regulatory, integrative and comparative physiology.

[12]  D. Gozal,et al.  Sleep Fragmentation During Late Gestation Induces Metabolic Perturbations and Epigenetic Changes in Adiponectin Gene Expression in Male Adult Offspring Mice , 2014, Diabetes.

[13]  H. Vidal,et al.  Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice , 2014, Diabetologia.

[14]  S. Marciniak,et al.  The integrated stress response in lung disease. , 2014, American journal of respiratory cell and molecular biology.

[15]  R. Arsenescu,et al.  Adipose Tissue Immune Response: Novel Triggers and Consequences for Chronic Inflammatory Conditions , 2014, Inflammation.

[16]  L. J. Lee,et al.  Epigenetic regulation of connective tissue growth factor by MicroRNA‐214 delivery in exosomes from mouse or human hepatic stellate cells , 2014, Hepatology.

[17]  Hong Wang,et al.  Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases , 2014, Biomarker Research.

[18]  J. Baur,et al.  Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism , 2013, Aging cell.

[19]  J. Kalbfleisch,et al.  Snoring during pregnancy and delivery outcomes: a cohort study. , 2013, Sleep.

[20]  K. Flegal,et al.  Prevalence of obesity among adults: United States, 2011-2012. , 2013, NCHS data brief.

[21]  S. Redline,et al.  Sleep-Disordered Breathing and Gestational Diabetes Mellitus , 2013, Diabetes Care.

[22]  M. St-Onge,et al.  Sleep duration and disorders in pregnancy: implications for glucose metabolism and pregnancy outcomes , 2013, International Journal of Obesity.

[23]  B. Hutchison,et al.  A postal survey of maternal sleep in late pregnancy , 2012, BMC Pregnancy and Childbirth.

[24]  D. Gozal,et al.  Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathway , 2012, Journal of Neuroinflammation.

[25]  Hong Chen,et al.  Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. , 2012, Journal of hepatology.

[26]  C. Mathieu,et al.  Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance , 2012, Diabetologia.

[27]  Sana Basseri,et al.  Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential , 2011, Biochemistry research international.

[28]  D. Gozal,et al.  Sleep fragmentation induces cognitive deficits via nicotinamide adenine dinucleotide phosphate oxidase-dependent pathways in mouse. , 2011, American journal of respiratory and critical care medicine.

[29]  V. Mohsenin,et al.  Sleep-disordered breathing in pregnancy. , 2011, Clinics in chest medicine.

[30]  S. Tufik,et al.  Biochemical, biometrical and behavioral changes in male offspring of sleep-deprived mice , 2010, Psychoneuroendocrinology.

[31]  K. Flegal,et al.  Prevalence and trends in obesity among US adults, 1999-2008. , 2010, JAMA.

[32]  M. Kryger,et al.  Sleep breathing disorders in the U.S. female population. , 2009, Journal of women's health.

[33]  J. Zieleński,et al.  Normalization of Obesity-Associated Insulin Resistance through Immunotherapy: CD4+ T Cells Control Glucose Homeostasis , 2009, Nature Medicine.

[34]  R. Simmons.  Perinatal programming of obesity. , 2008, Seminars in perinatology.

[35]  Yan Zhu,et al.  Aging Impairs the Unfolded Protein Response to Sleep Deprivation and Leads to Proapoptotic Signaling , 2008, The Journal of Neuroscience.

[36]  N. Naidoo,et al.  Eif-2a Protects Brainstem Motoneurons in a Murine Model of Sleep Apnea , 2008, The Journal of Neuroscience.

[37]  A. Saltiel,et al.  Obesity induces a phenotypic switch in adipose tissue macrophage polarization. , 2007, The Journal of clinical investigation.

[38]  A. Saltiel,et al.  Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity , 2007, Diabetes.

[39]  A. Pack,et al.  Sleep deprivation induces the unfolded protein response in mouse cerebral cortex , 2005, Journal of neurochemistry.

[40]  D. Ron,et al.  CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. , 2004, Genes & development.

[41]  L. Glimcher,et al.  Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes , 2004, Science.

[42]  P. Sahota,et al.  Sleep disorders in pregnancy , 2003, Current opinion in pulmonary medicine.

[43]  S. Akira,et al.  The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress—elucidation by GADD34‐deficient mice , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[44]  R. Kaufman,et al.  Phosphorylation of Eukaryotic Translation Initiation Factor 2 Mediates Apoptosis in Response to Activation of the Double-stranded RNA-dependent Protein Kinase* , 1998, The Journal of Biological Chemistry.

[45]  R. Turner,et al.  Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man , 1985, Diabetologia.

[46]  D. Gozal,et al.  Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice. , 2015, Sleep.