Research and development of drug delivery systems based on drug transporter and nano-formulation

[1]  H. Chavda,et al.  Biopharmaceutics classification system , 2010 .

[2]  V. Ganapathy,et al.  Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5) , 2018, Expert opinion on therapeutic targets.

[3]  Zhenzhen Wu,et al.  A large-inner-diameter multi-walled carbon nanotube-based dual-drug delivery system with pH-sensitive release properties , 2017, Journal of Materials Science: Materials in Medicine.

[4]  B. Pickard,et al.  PEGylation of polypropylenimine dendrimers: effects on cytotoxicity, DNA condensation, gene delivery and expression in cancer cells , 2018, Scientific Reports.

[5]  P. Gaillard,et al.  The role of drug transporters at the blood-brain barrier. , 2003, Annual review of pharmacology and toxicology.

[6]  R. Levy,et al.  Intestinal Drug Interactions Mediated by OATPs: A Systematic Review of Preclinical and Clinical Findings. , 2017, Journal of pharmaceutical sciences.

[7]  M. Dobrovolskaia Dendrimers Effects on the Immune System: Insights into Toxicity and Therapeutic Utility. , 2017, Current pharmaceutical design.

[8]  B. Hagenbuch,et al.  OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies , 2012, British journal of pharmacology.

[9]  S. Flora,et al.  Nanocrystals: An Overview of Fabrication, Characterization and Therapeutic Applications in Drug Delivery. , 2019, Current pharmaceutical design.

[10]  A. Tsuji,et al.  P-glycoprotein-mediated efflux transport of anticancer drugs at the blood-brain barrier. , 1998, Therapeutic drug monitoring.

[11]  D. Keppler,et al.  Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma , 2001, International journal of cancer.

[12]  F. Ahmad,et al.  RETRACTED ARTICLE: Preparation and characterization of surface-modified PLGA-polymeric nanoparticles used to target treatment of intestinal cancer , 2018, Artificial cells, nanomedicine, and biotechnology.

[13]  W. Kamoun,et al.  Formulation optimization of an ephrin A2 targeted immunoliposome encapsulating reversibly modified taxane prodrugs. , 2019, Journal of controlled release : official journal of the Controlled Release Society.

[14]  A. Elhissi Liposomes for Pulmonary Drug Delivery: The Role of Formulation and Inhalation Device Design. , 2017, Current pharmaceutical design.

[15]  Hui Liu,et al.  Loading IR820 Using Multifunctional Dendrimers with Enhanced Stability and Specificity , 2018, Pharmaceutics.

[16]  Lu Wang,et al.  siRNA capsulated brain-targeted nanoparticles specifically knock down OATP2B1 in mice: a mechanism for acute morphine tolerance suppression , 2016, Scientific Reports.

[17]  Guimei Lin,et al.  Study of the pH-sensitive mechanism of tumor-targeting liposomes. , 2017, Colloids and surfaces. B, Biointerfaces.

[18]  H. Koepsell,et al.  Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications , 2007, Pharmaceutical Research.

[19]  M. Fromm,et al.  Pharmacogenomics of human OATP transporters , 2006, Naunyn-Schmiedeberg's Archives of Pharmacology.

[20]  N. Voelcker,et al.  Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma , 2018, Journal of Nanobiotechnology.

[21]  S. Bharate,et al.  Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer. , 2017, European journal of medicinal chemistry.

[22]  F. Wang,et al.  Synthesis and characterization of poly(lactic acid-co-glycolic acid) complex microspheres as drug carriers , 2016, Journal of biomaterials applications.

[23]  M. Niemi,et al.  Impact of OATP transporters on pharmacokinetics , 2009, British journal of pharmacology.

[24]  N. Picard,et al.  Multidrug resistance-associated protein 4 in pharmacology: Overview of its contribution to pharmacokinetics, pharmacodynamics and pharmacogenetics. , 2019, Life sciences.

[25]  Sherief Essa,et al.  Effect of polyethylene glycol (PEG) chain organization on the physicochemical properties of poly(D, L-lactide) (PLA) based nanoparticles. , 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[26]  F. Mahjoubi,et al.  MDR1 gene polymorphisms: possible association with its expression and clinicopathology characteristics in colorectal cancer patients. , 2011, Asian Pacific journal of cancer prevention : APJCP.

[27]  P. Pávek,et al.  Breast cancer resistance protein (BCRP/ABCG2). , 2005, The international journal of biochemistry & cell biology.

[28]  J. Varshosaz,et al.  Hollow Inorganic Nanoparticles as Efficient Carriers for siRNA Delivery: A Comprehensive Review. , 2015, Current pharmaceutical design.

[29]  A. M. Al-Abd,et al.  P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review , 2014, Journal of advanced research.

[30]  W. Sadee,et al.  Intra- and Interindividual Variabilities of Valacyclovir Oral Bioavailability and Effect of Coadministration of an hPEPT1 Inhibitor , 2003, Antimicrobial Agents and Chemotherapy.

[31]  Hyung Jun Ahn,et al.  PLGA nanoparticles co-delivering MDR1 and BCL2 siRNA for overcoming resistance of paclitaxel and cisplatin in recurrent or advanced ovarian cancer , 2018, Scientific Reports.

[32]  M. S. Muthu,et al.  Transferrin receptor-targeted vitamin E TPGS micelles for brain cancer therapy: preparation, characterization and brain distribution in rats , 2016, Drug delivery.

[33]  Sungpil Yoon,et al.  P-gp Inhibition by XL019, a JAK2 Inhibitor, Increases Apoptosis of Vincristine-treated Resistant KBV20C Cells with Increased p21 and pH2AX Expression. , 2017, Anticancer research.

[34]  Xin Ma,et al.  Nanocrystals Technology for Pharmaceutical Science. , 2018, Current pharmaceutical design.

[35]  J. Li,et al.  Overcoming Multidrug Resistance by Codelivery of MDR1-Targeting siRNA and Doxorubicin Using EphA10-Mediated pH-Sensitive Lipoplexes: In Vitro and In Vivo Evaluation. , 2018, ACS applied materials & interfaces.

[36]  Hideyuki Saito,et al.  Gene expression levels and immunolocalization of organic ion transporters in the human kidney. , 2002, Journal of the American Society of Nephrology : JASN.

[37]  W. Hua,et al.  The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins. , 2012, Cardiovascular therapeutics.

[38]  S. Cole,et al.  Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. , 2005, Toxicology and applied pharmacology.

[39]  Adam E. M. Eltorai,et al.  Microchips in Medicine: Current and Future Applications , 2016, BioMed research international.

[40]  J. Iqbal,et al.  Targeted Drug Delivery Systems and Their Therapeutic Applications in Cancer and Immune Pathological Conditions. , 2017, Infectious disorders drug targets.

[41]  D. Mishra,et al.  Carbon Nanotubes: Classification, Method of Preparation and Pharmaceutical Application. , 2017, Current drug delivery.

[42]  A. Tiwary,et al.  Antimalarial solid self-emulsifying system for oral use: in vitro investigation. , 2017, Therapeutic delivery.

[43]  A. Schätzlein,et al.  Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate. , 2016, International journal of pharmaceutics.

[44]  F. Remião,et al.  Opioids and the Blood-Brain Barrier: A Dynamic Interaction with 
Consequences on Drug Disposition in Brain , 2017, Current neuropharmacology.

[45]  M. Trauner,et al.  Bile acid transporters and regulatory nuclear receptors in the liver and beyond , 2013, Journal of hepatology.

[46]  H. Koepsell Role of organic cation transporters in drug–drug interaction , 2015, Expert opinion on drug metabolism & toxicology.

[47]  Qingcheng Mao,et al.  Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update , 2014, The AAPS Journal.

[48]  Shulan Huang,et al.  Down-Regulation of MRP1 Expression in C6/VP16 Cells by Chitosan-MRP1-siRNA Nanoparticles , 2015, Cell Biochemistry and Biophysics.

[49]  A. Rey-Rico,et al.  PEO-PPO-PEO Tri-Block Copolymers for Gene Delivery Applications in Human Regenerative Medicine—An Overview , 2018, International journal of molecular sciences.

[50]  K. Yan,et al.  Cationic liposome codelivering PI3K pathway regulator improves the response of BRCA1‐deficient breast cancer cells to PARP1 inhibition , 2019, Journal of cellular biochemistry.

[51]  V. Patravale,et al.  Transmucosal Nanoparticles: Toxicological Overview. , 2018, Advances in experimental medicine and biology.

[52]  Masanori Nakakariya,et al.  Appropriate risk criteria for OATP inhibition at the drug discovery stage based on the clinical relevancy between OATP inhibitors and drug-induced adverse effect. , 2016, Drug metabolism and pharmacokinetics.

[53]  F. Kiessling,et al.  Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[54]  M. Kool,et al.  Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. , 2000, Cancer research.

[55]  J. Schellens,et al.  Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP , 2012, Investigational New Drugs.

[56]  D. Douer Efficacy and Safety of Vincristine Sulfate Liposome Injection in the Treatment of Adult Acute Lymphocytic Leukemia. , 2016, The oncologist.

[57]  C. Ehrhardt,et al.  Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro , 2017, Pharmaceutical Research.

[58]  Jia-Lin Yang,et al.  Nanoparticle-siRNA: A potential cancer therapy? , 2016, Critical reviews in oncology/hematology.

[59]  Magnetic-Immuno-Loop-Mediated Isothermal Amplification Based on DNA Encapsulating Liposome for the Ultrasensitive Detection of P-glycoprotein , 2017, Scientific Reports.

[60]  Yanan Liu,et al.  Sialic acid (SA)-modified selenium nanoparticles coated with a high blood-brain barrier permeability peptide-B6 peptide for potential use in Alzheimer's disease. , 2015, Acta biomaterialia.

[61]  Vasilis Vasiliou,et al.  Human ATP-binding cassette (ABC) transporter family , 2009, Human Genomics.

[62]  Dinesh Kumar,et al.  Micellar carriers for the delivery of multiple therapeutic agents. , 2015, Colloids and surfaces. B, Biointerfaces.

[63]  I. Rubio-Aliaga,et al.  Mammalian peptide transporters as targets for drug delivery. , 2002, Trends in pharmacological sciences.

[64]  K. Kalia,et al.  Surface Engineered Dendrimers in siRNA Delivery and Gene Silencing. , 2017, Current pharmaceutical design.

[65]  Hua Sun,et al.  Composition design and medical application of liposomes. , 2019, European journal of medicinal chemistry.

[66]  V. Šubr,et al.  Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate. , 2017, Biomaterials.

[67]  M. Zoli,et al.  PEG-g-chitosan nanoparticles functionalized with the monoclonal antibody OX26 for brain drug targeting. , 2015, Nanomedicine.

[68]  Jiayi Pan,et al.  Dendrimers as Nanocarriers for Nucleic Acid and Drug Delivery in Cancer Therapy , 2017, Molecules.

[69]  K. B. Sutradhar,et al.  Implantable microchip: the futuristic controlled drug delivery system , 2016, Drug delivery.

[70]  Kee W. Tan,et al.  High‐content screening of clinically tested anticancer drugs identifies novel inhibitors of human MRP1 (ABCC1) , 2017, Pharmacological research.

[71]  M. Yeh,et al.  Biodegradable polymeric microsphere-based vaccines and their applications in infectious diseases , 2015, Human vaccines & immunotherapeutics.

[72]  R. Neubert,et al.  Drug specificity and intestinal membrane localization of human organic cation transporters (OCT). , 2005, Biochemical pharmacology.

[73]  M. El-Badry,et al.  Self-emulsifying drug-delivery systems modulate P-glycoprotein activity: role of excipients and formulation aspects. , 2018, Nanomedicine.

[74]  E. Cocucci,et al.  Role of Passive Diffusion, Transporters, and Membrane Trafficking‐Mediated Processes in Cellular Drug Transport , 2017, Clinical pharmacology and therapeutics.

[75]  M. Leopoldo,et al.  Design and Synthesis of New Selective P-gp Substrates and Inhibitors. , 2016, Current pharmaceutical design.

[76]  Huijun Sun,et al.  Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs) , 2019, Acta pharmaceutica Sinica. B.

[77]  A. Yari Khosroushahi,et al.  Polymeric micelles as mighty nanocarriers for cancer gene therapy: a review , 2017, Cancer chemotherapy and pharmacology.

[78]  Xin Jin,et al.  Ascorbyl palmitate/d-α-tocopheryl polyethylene glycol 1000 succinate monoester mixed micelles for prolonged circulation and targeted delivery of compound K for antilung cancer therapy in vitro and in vivo , 2017, International journal of nanomedicine.

[79]  A. K. Kondapi,et al.  Evaluation of Antiproliferative Activity, Safety and Biodistribution of Oxaliplatin and 5-Fluorouracil Loaded Lactoferrin Nanoparticles for the Management of Colon Adenocarcinoma: an In Vitro and an In Vivo Study , 2018, Pharmaceutical Research.

[80]  R. Piñol,et al.  PEG-copolymer-coated iron oxide nanoparticles that avoid the reticuloendothelial system and act as kidney MRI contrast agents. , 2018, Nanoscale.

[81]  J. Irache,et al.  Oral delivery of camptothecin using cyclodextrin/poly(anhydride) nanoparticles. , 2016, International journal of pharmaceutics.

[82]  Sushant Lakkadwala,et al.  Co-delivery of doxorubicin and erlotinib through liposomal nanoparticles for glioblastoma tumor regression using an in vitro brain tumor model. , 2019, Colloids and surfaces. B, Biointerfaces.

[83]  Jing Zhao,et al.  Polyester-based nanoparticles for nucleic acid delivery. , 2018, Materials science & engineering. C, Materials for biological applications.

[84]  Zhe Chen,et al.  Chinese a Nti鄄 Cancer a Ssociation , 2022 .

[85]  Xingzhong Zhao,et al.  Synthetic nanoparticles camouflaged with biomimetic erythrocyte membranes for reduced reticuloendothelial system uptake , 2016, Nanotechnology.

[86]  M. Staples Microchips and controlled-release drug reservoirs. , 2010, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[87]  R. Masereeuw,et al.  A Human Renal Proximal Tubule Cell Line with Stable Organic Anion Transporter 1 and 3 Expression Predictive for Antiviral-Induced Toxicity , 2016, The AAPS Journal.

[88]  D. Burgess,et al.  Recent advances in testing of microsphere drug delivery systems , 2016, Expert opinion on drug delivery.

[89]  G. Burckhardt,et al.  Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, Physiological, and Pathological Roles , 2007, Pharmaceutical Research.

[90]  A. Salifoglou,et al.  Magnetic cationic liposomal nanocarriers for the efficient drug delivery of a curcumin-based vanadium complex with anticancer potential. , 2019, Journal of inorganic biochemistry.

[91]  A. Mathur,et al.  Comparative analysis of single-walled and multi-walled carbon nanotubes for electrochemical sensing of glucose on gold printed circuit boards. , 2018, Materials science & engineering. C, Materials for biological applications.

[92]  M. Kumar,et al.  Improved anti-tumor activity of oxaliplatin by encapsulating in anti-DR5 targeted gold nanoparticles , 2016, Drug delivery.

[93]  Sanghyo Kim,et al.  Recent insights into the development of nucleic acid-based nanoparticles for tumor-targeted drug delivery. , 2018, Colloids and surfaces. B, Biointerfaces.

[94]  S. Talegaonkar,et al.  Novel flavonoid-based biodegradable nanoparticles for effective oral delivery of etoposide by P-glycoprotein modulation: an in vitro, ex vivo and in vivo investigations , 2016, Drug delivery.

[95]  Ajazuddin,et al.  Recent advancements in liposomes targeting strategies to cross blood‐brain barrier (BBB) for the treatment of Alzheimer's disease , 2017, Journal of controlled release : official journal of the Controlled Release Society.

[96]  Gert Storm,et al.  Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release , 2010, Pharmaceutical Research.

[97]  K. Sawant,et al.  Mucoadhesive microspheres: a promising tool in drug delivery. , 2008, Current drug delivery.

[98]  U. Bogdahn,et al.  Long‐term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin , 2001, Cancer.

[99]  Na Li,et al.  Development and evaluation of a novel phytosome-loaded chitosan microsphere system for curcumin delivery. , 2013, International journal of pharmaceutics.

[100]  G. Burckhardt Drug transport by Organic Anion Transporters (OATs). , 2012, Pharmacology & therapeutics.

[101]  P. Sharma,et al.  Advancement in microsphere preparation using natural polymers and recent patents. , 2014, Recent patents on drug delivery & formulation.

[102]  Huang-Ping Yu,et al.  Injectable Drug-Loaded Nanocarriers for Lung Cancer Treatments. , 2017, Current pharmaceutical design.

[103]  M. Yokoyama Polymeric micelles as drug carriers: their lights and shadows , 2014, Journal of drug targeting.

[104]  R. Ramesh,et al.  Tumor-Targeted Dendrimer Nanoparticles for Combinatorial Delivery of siRNA and Chemotherapy for Cancer Treatment. , 2020, Methods in molecular biology.

[105]  M. Mokhtar,et al.  Design of PEG-grafted-PLA nanoparticles as oral permeability enhancer for P-gp substrate drug model Famotidine , 2017, Journal of microencapsulation.

[106]  Pallab Pradhan,et al.  Targeted temperature sensitive magnetic liposomes for thermo-chemotherapy. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[107]  K. Gowthamarajan,et al.  Oxaliplatin immuno hybrid nanoparticles for active targeting: an approach for enhanced apoptotic activity and drug delivery to colorectal tumors , 2016, Drug delivery.

[108]  V. Torchilin,et al.  Polyamidoamine dendrimers‐based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance , 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[109]  W. Dehaen,et al.  Selenium-Platinum Coordination Dendrimers with Controlled Anti-Cancer Activity. , 2016, ACS applied materials & interfaces.

[110]  A. Akbarzadeh,et al.  Reversion of Multidrug Resistance by Co-Encapsulation of Doxorubicin and Metformin in Poly(lactide-co-glycolide)-d-α-tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles , 2018, Pharmaceutical Research.

[111]  Youtao Xu,et al.  L-BLP25 as a peptide vaccine therapy in non-small cell lung cancer: a review. , 2014, Journal of thoracic disease.

[112]  Y. Assaraf,et al.  &bgr;‐Casein micelles for oral delivery of SN‐38 and elacridar to overcome BCRP‐mediated multidrug resistance in gastric cancer , 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[113]  Young Bin Choy,et al.  Implantable micro-chip for controlled delivery of diclofenac sodium. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[114]  Leslie Z Benet,et al.  Intestinal drug transporters: an overview. , 2013, Advanced drug delivery reviews.

[115]  X. Jing,et al.  Curcumin-loaded PLGA-PEG nanoparticles conjugated with B6 peptide for potential use in Alzheimer’s disease , 2018, Drug delivery.

[116]  T. Iwatsubo,et al.  Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1–3 in vitro and implications for drug–drug interactions , 2008 .

[117]  W. Duan,et al.  Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development. , 2008, Current medicinal chemistry.

[118]  Fabian Müller,et al.  Transporters and Drug-Drug Interactions: Important Determinants of Drug Disposition and Effects , 2013, Pharmacological Reviews.

[119]  C. Benz,et al.  Development of ligand-targeted liposomes for cancer therapy , 2004, Expert opinion on therapeutic targets.

[120]  R. Béliveau,et al.  Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier. , 2002, Vascular pharmacology.

[121]  M. Hiasa,et al.  The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations. , 2006, Trends in pharmacological sciences.

[122]  D. Chiappetta,et al.  Polymeric mixed micelles as nanomedicines: Achievements and perspectives. , 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[123]  A. Yu,et al.  ABC transporters in multidrug resistance and pharmacokinetics, and strategies for drug development. , 2014, Current pharmaceutical design.

[124]  Jiechao Ge,et al.  Near-infrared fluorescent carbon dots encapsulated liposomes as multifunctional nano-carrier and tracer of the anticancer agent cinobufagin in vivo and in vitro. , 2019, Colloids and surfaces. B, Biointerfaces.

[125]  C. Gong,et al.  LHD-Modified Mechanism-Based Liposome Coencapsulation of Mitoxantrone and Prednisolone Using Novel Lipid Bilayer Fusion for Tissue-Specific Colocalization and Synergistic Antitumor Effects. , 2016, ACS applied materials & interfaces.

[126]  Xiaolong Liu,et al.  Reduction/photo dual-responsive polymeric prodrug nanoparticles for programmed siRNA and doxorubicin delivery. , 2018, Biomaterials science.

[127]  Russell J Mumper,et al.  Doxorubicin and paclitaxel-loaded lipid-based nanoparticles overcome multidrug resistance by inhibiting P-glycoprotein and depleting ATP. , 2009, Cancer research.

[128]  S. Zeng,et al.  Epigenetic activation of the drug transporter OCT2 sensitizes renal cell carcinoma to oxaliplatin , 2016, Science Translational Medicine.

[129]  Eichman,et al.  The use of PAMAM dendrimers in the efficient transfer of genetic material into cells. , 2000, Pharmaceutical science & technology today.

[130]  Wei Tang,et al.  Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans Cantor. , 2011, International immunopharmacology.

[131]  Xing-jie Liang,et al.  The Promising Nanocarrier for Doxorubicin and siRNA Co-delivery by PDMAEMA-based Amphiphilic Nanomicelles. , 2016, ACS applied materials & interfaces.

[132]  Xinguo Jiang,et al.  The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2. , 2012, Biomaterials.

[133]  Linyin Feng,et al.  Transferrin-conjugated polyphosphoester hybrid micelle loading paclitaxel for brain-targeting delivery: synthesis, preparation and in vivo evaluation. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[134]  Emad B. Basalious,et al.  Contribution of both olfactory and systemic pathways for brain targeting of nimodipine-loaded lipo-pluronics micelles: in vitro characterization and in vivo biodistribution study after intranasal and intravenous delivery , 2017, Drug delivery.

[135]  D. Ross,et al.  Chinese a Nti鄄 Cancer a Ssociation , 2022 .

[136]  Xiaochi Ma,et al.  Organic anion transporter 3 (OAT3)‐mediated transport of dicaffeoylquinic acids and prediction of potential drug‐drug interaction , 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[137]  W. Banks,et al.  Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease? , 2017, Acta Neuropathologica Communications.

[138]  Hong Yuan,et al.  Rational Design of Redox‐Responsive and P‐gp‐Inhibitory Lipid Nanoparticles with High Entrapment of Paclitaxel for Tumor Therapy , 2018, Advanced healthcare materials.

[139]  A. Madgulkar,et al.  Improvement of Oral Bioavailability of Lopinavir Without Co-administration of Ritonavir Using Microspheres of Thiolated Xyloglucan , 2017, AAPS PharmSciTech.

[140]  Wensyang Hsu,et al.  An Implantable Drug-delivery System on a Chip. , 2015, Current topics in medicinal chemistry.

[141]  Claudia Battistella,et al.  Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates. , 2017, Biomacromolecules.

[142]  L. Chow,et al.  Flavonoids as P-gp inhibitors: a systematic review of SARs. , 2019, Current medicinal chemistry.

[143]  Tapan K. Dash,et al.  Selection of P-Glycoprotein Inhibitor and Formulation of Combinational Nanoformulation Containing Selected Agent Curcumin and DOX for Reversal of Resistance in K562 Cells , 2017, Pharmaceutical Research.