Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990–2010: a systematic review and analysis

Methods In our systematic review we searched for reports of Alzheimer’s disease or dementia in China, published in Chinese and English between 1990 and 2010. We searched China National Knowledge Infrastructure, Wanfang, and PubMed databases. Two investigators independently assessed case defi nitions of Alzheimer’s disease and dementia: we excluded studies that did not use internationally accepted case defi nitions. We also excluded reviews and viewpoints, studies with no numerical estimates, and studies not done in mainland China. We used Poisson regression and UN demographic data to estimate the prevalence (in nine age groups), incidence, and standardised mortality ratio of dementia and its subtypes in China in 1990, 2000, and 2010.

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