Bipolar Sealer Devices Used in Posterior Spinal Fusion for Neuromuscular Scoliosis Reduce Blood Loss and Transfusion Requirements

Background:Reducing perioperative blood loss and the need for transfusions in patients undergoing spinal surgery is especially important for those with neuromuscular disorders. These patients require extensive spino-pelvic exposure and are often medically fragile. We have used Amicar to decrease blood loss since 2001. As an effort to further reduce blood loss and transfusions, we use a bipolar sealer device (Aquamantys) as an adjunct to electrocautery. We present the results of our first 64 neuromuscular patients to show the efficacy of the device. Methods:Using a prospectively maintained database we reviewed the operative time, estimated perioperative blood loss, cell saver use, and intraoperative and postoperative transfusion rate in patients who underwent posterior spinal fusion for neuromuscular scoliosis. Sixty-four patients were identified who fit these criteria since the use of the bipolar sealer device was instituted.We compared these patients with a control group of the preceding 65 patients in whom this device was not used for hemostasis. All patients, including those in the study group, received Amicar (infusion of 100 mg/kg over 15 to 20 min, then 10 mg/kg/h throughout the remainder of the procedure). The surgical technique did not differ between the 2 groups. Results:Baseline characteristics between the 2 groups were similar except for the number of patients having an all-screw construct which was larger in the investigational group (25% vs. 8%, P=0.03). There were no significant differences in operative time or duration of hospital stay. Intraoperative blood loss was lower in the study group (741 mL) as compared with the control group (1052 mL, P=0.003). Total perioperative blood loss, however, showed no significant difference. Thirty-five (55%) patients in the study group and 50 (77%) patients in the control group required additional intraoperative or postoperative transfusions (P=0.01). The number of packed red cell units transfused per patient was 0.81 in the study group and 1.57 in the control group (P=0.001). Although the intraoperative cell saver transfusion was same, the total blood volume transfused, which includes cell saver and any other transfusions, was significantly lower in the study group, 425 mL versus 671 mL (P=0.002). Conclusions:Use of a bipolar sealer device in posterior spinal fusion for neuromuscular scoliosis significantly reduced intraoperative blood loss and transfusion rate when compared with a control group in this retrospective review. Level of Evidence:Level III—retrospective comparative study.

[1]  Rachel N. Rattenni,et al.  Efficacy of tranexamic acid on surgical bleeding in spine surgery: a meta-analysis. , 2015, The spine journal : official journal of the North American Spine Society.

[2]  J. Son-Hing,et al.  Bipolar Sealer Device Reduces Blood Loss and Transfusion Requirements in Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis , 2013, Journal of pediatric orthopedics.

[3]  F. Schwab,et al.  Efficacy of Tranexamic Acid and Aminocaproic Acid on Bleeding in Spine Surgery: A Meta-Analysis , 2013 .

[4]  R. Khemani,et al.  Tranexamic Acid Reduces PRBC Transfusion after Posterior Spine Surgeryfor Idiopathic Scoliosis from the Operating Room to Post-Operative DayFour , 2013 .

[5]  C. Moore,et al.  Hemostasis With a Bipolar Sealer During Surgical Correction of Adolescent Idiopathic Scoliosis , 2012, Journal of spinal disorders & techniques.

[6]  S. Rajasekaran,et al.  Blood management in pediatric spinal deformity surgery: review of a 2‐year experience , 2011, Transfusion.

[7]  W. Barsoum,et al.  Prospective randomized evaluation of the need for blood transfusion during primary total hip arthroplasty with use of a bipolar sealer. , 2011, The Journal of bone and joint surgery. American volume.

[8]  Dionne A. Graham,et al.  Risk factors for surgical site infection after cardiac surgery in children. , 2010, The Annals of thoracic surgery.

[9]  T. Errico,et al.  A prospective, randomized, double-blinded single-site control study comparing blood loss prevention of tranexamic acid (TXA) to epsilon aminocaproic acid (EACA) for corrective spinal surgery , 2010, BMC surgery.

[10]  S. Curley,et al.  Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy: analysis of 1,557 consecutive liver resections. , 2010, Surgery.

[11]  V. Goldberg,et al.  Hemostasis using a bipolar sealer in primary unilateral total knee arthroplasty. , 2009, American journal of orthopedics.

[12]  D. Armstrong,et al.  Role of Amicar in Surgery for Neuromuscular Scoliosis , 2008, Spine.

[13]  Dierick R Sparks,et al.  The use of bipolar hemosealing technology in orthopedic oncology: safety and clinical impact. , 2008, Orthopedics.

[14]  D. Armstrong,et al.  The Role of Amicar in Same-Day Anterior and Posterior Spinal Fusion for Idiopathic Scoliosis , 2008, Spine.

[15]  T. Seyler,et al.  Reductions in blood loss with a bipolar sealer in total hip arthroplasty , 2008, Expert review of medical devices.

[16]  Christopher Lawrence,et al.  Surgery , 1899, The Lancet.

[17]  R. Betz,et al.  Strategies to reduce blood loss during posterior spinal fusion for neuromuscular scoliosis: a review of current techniques and experience with a unique bipolar electrocautery device. , 2008, Surgical technology international.

[18]  A. Rosenberg Reducing blood loss in total joint surgery with a saline-coupled bipolar sealing technology. , 2007, The Journal of arthroplasty.

[19]  D. Chinkes,et al.  Blood transfusions are associated with increased risk for development of sepsis in severely burned pediatric patients* , 2007, Critical care medicine.

[20]  D. Armstrong,et al.  Fibrinogen Levels Following Amicar in Surgery for Idiopathic Scoliosis , 2007, Spine.

[21]  P. Learn,et al.  Laparoscopic hepatic resection using saline-enhanced electrocautery permits short hospital stays , 2006, Journal of Gastrointestinal Surgery.

[22]  R. Gamelli,et al.  Effect of blood transfusion on outcome after major burn injury: A multicenter study , 2007 .

[23]  C. Poe-Kochert,et al.  The Role of Amicar in Decreasing Perioperative Blood Loss in Idiopathic Scoliosis , 2005, Spine.

[24]  F. Shapiro,et al.  Blood loss in pediatric spine surgery , 2004, European Spine Journal.

[25]  O. Boachie-Adjei,et al.  Outcome of Pediatric Patients With Severe Restrictive Lung Disease Following Reconstructive Spine Surgery , 2004, Spine.

[26]  L. Blakemore,et al.  The Effect of Amicar on Perioperative Blood Loss in Idiopathic Scoliosis:: The Results of a Prospective, Randomized Double-Blind Study , 2004, Spine.

[27]  D. Murray,et al.  Blood loss during posterior spinal fusion surgery in patients with neuromuscular disease: is there an increased risk? , 2003, Paediatric anaesthesia.

[28]  E. Rendina,et al.  A new technological approach to nonanatomical pulmonary resection: saline enhanced thermal sealing. , 2002, The Annals of thoracic surgery.

[29]  S. Kannan,et al.  Bleeding and coagulation changes during spinal fusion surgery: A comparison of neuromuscular and idiopathic scoliosis patients , 2002, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[30]  S. Kannan,et al.  Predictors of Red Cell Transfusion in Children and Adolescents Undergoing Spinal Fusion Surgery , 2002, Spine.

[31]  L. Blakemore,et al.  The Effect of &egr;-Aminocaproic Acid on Perioperative Blood Loss in Patients With Idiopathic Scoliosis Undergoing Posterior Spinal Fusion: A Preliminary Prospective Study , 2001, Spine.

[32]  S. Leal-Noval,et al.  Transfusion of blood components and postoperative infection in patients undergoing cardiac surgery. , 2001, Chest.

[33]  M. Guertin,et al.  Predicting blood loss in surgery for idiopathic scoliosis , 1994, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[34]  R. Hensinger,et al.  CONTROL OF BLOOD LOSS DURING SCOLIOSIS SURGERY , 1988, Clinical orthopaedics and related research.

[35]  S. Paskin,et al.  Induced moderate hypotensive anesthesia for spinal fusion and Harrington-rod instrumentation. , 1985, The Journal of bone and joint surgery. American volume.

[36]  K. Kuo,et al.  Controlled hypotensive anesthesia in scoliosis surgery. , 1974, The Journal of bone and joint surgery. American volume.

[37]  H. Cowell,et al.  Autotransfusion in children's orthopaedics. , 1974, The Journal of bone and joint surgery. American volume.

[38]  J E Relton,et al.  An operation frame for spinal fusion. A new apparatus designed to reduce haemorrhage during operation. , 1967, The Journal of bone and joint surgery. British volume.

[39]  H. Johnson,et al.  Formation of a functional thumb post with sensation in phocomelia. , 1967, The Journal of bone and joint surgery. American volume.