Homology analysis detects topological changes of Iba1 localization accompanied by microglial activation

[1]  H. Hara,et al.  Neuroprotective Effect of Recombinant Human Granulocyte Colony-Stimulating Factor in Transient Focal Ischemia of Mice , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[2]  Tracy J. Yuen,et al.  M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination , 2013, Nature Neuroscience.

[3]  R. Leak,et al.  Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia , 2012, Stroke.

[4]  W. Gan,et al.  ATP mediates rapid microglial response to local brain injury in vivo , 2005, Nature Neuroscience.

[5]  C. Iadecola,et al.  Spatio-temporal profile, phenotypic diversity, and fate of recruited monocytes into the post-ischemic brain , 2016, Journal of Neuroinflammation.

[6]  T. Hökfelt,et al.  Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[7]  M. Zaremba,et al.  Quantitative morphological study of microglial cells in the ischemic rat brain using principal component analysis , 2005, Journal of Neuroscience Methods.

[8]  Y. Suzuki,et al.  Effects of GM‐CSF and ordinary supplements on the ramification of microglia in culture: A morphometrical study , 1996, Glia.

[9]  R. Pawlinski,et al.  Morphology of reactive microglia in the injured cerebral cortex. Fractal analysis and complementary quantitative methods , 2001, Journal of neuroscience research.

[10]  S. Akira,et al.  TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus , 2015, Nature Communications.

[11]  E. Ringelstein,et al.  Predominant phagocytic activity of resident microglia over hematogenous macrophages following transient focal cerebral ischemia: An investigation using green fluorescent protein transgenic bone marrow chimeric mice , 2005, Experimental Neurology.

[12]  F. Heppner,et al.  Vitamin E induces ramification and downregulation of adhesion molecules in cultured microglial cells , 1998, Glia.

[13]  J. Nabekura,et al.  Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals , 2009, The Journal of Neuroscience.

[14]  B. Felding-Habermann,et al.  Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis. , 2010, The American journal of pathology.

[15]  V. Perry,et al.  The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration , 1991, Neuroscience.

[16]  B. Lin,et al.  Fractalkine receptor regulates microglial neurotoxicity in an experimental mouse glaucoma model , 2014, Glia.

[17]  G. Kreutzberg Microglia: a sensor for pathological events in the CNS , 1996, Trends in Neurosciences.

[18]  D. Walker,et al.  Microglia in degenerative neurological disease , 1993, Glia.

[19]  J. Herman,et al.  Differential effects of homotypic vs. heterotypic chronic stress regimens on microglial activation in the prefrontal cortex , 2013, Physiology & Behavior.

[20]  G. Gowing,et al.  Selective Ablation of Proliferating Microglial Cells Exacerbates Ischemic Injury in the Brain , 2007, The Journal of Neuroscience.

[21]  A. Nimmerjahn,et al.  The Role of Microglia in the Healthy Brain , 2011, The Journal of Neuroscience.

[22]  Danny W. Wilson,et al.  Defining the Antigenic Diversity of Plasmodium falciparum Apical Membrane Antigen 1 and the Requirements for a Multi-Allele Vaccine against Malaria , 2012, PloS one.

[23]  T. Merchant,et al.  Rd permeability and leukocyte adhesion in the rat blood-brain barrier: modulation with anti-ICAM-1 antibodies , 2003 .

[24]  Midori A. Yenari,et al.  Microglial activation in stroke: Therapeutic targets , 2010, Neurotherapeutics.

[25]  G. Kreutzberg,et al.  Microglia: Intrinsic immuneffector cell of the brain , 1995, Brain Research Reviews.

[26]  Herbert F. Jelinek,et al.  Quantitating the subtleties of microglial morphology with fractal analysis , 2013, Front. Cell. Neurosci..

[27]  Y. Imai,et al.  A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. , 1996, Biochemical and biophysical research communications.

[28]  M. Yamada,et al.  Migration of enhanced green fluorescent protein expressing bone marrow-derived microglia/macrophage into the mouse brain following permanent focal ischemia , 2003, Neuroscience.

[29]  E. Ringelstein,et al.  Effects of monocyte chemoattractant protein 1 on blood-borne cell recruitment after transient focal cerebral ischemia in mice , 2009, Neuroscience.

[30]  D. Stern,et al.  A Reproducible and Simple Model of Permanent Cerebral Ischemia in CB-17 and SCID Mice. , 2010, Journal of experimental stroke & translational medicine.

[31]  Guohong Li,et al.  Inflammatory mechanisms in ischemic stroke: role of inflammatory cells , 2010, Journal of leukocyte biology.

[32]  U. Dirnagl,et al.  Pathophysiology of Stroke: Lessons from Animal Models , 2004, Metabolic Brain Disease.

[33]  L. Liaudet,et al.  Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.

[34]  J. Filosa,et al.  A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion , 2013, Journal of Neuroinflammation.

[35]  R. Leak,et al.  Microglial and macrophage polarization—new prospects for brain repair , 2015, Nature Reviews Neurology.

[36]  R. Gross,et al.  Adenosine A2A receptor mediates microglial process retraction , 2009, Nature Neuroscience.

[37]  Z. Fuks,et al.  Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiency. , 2000, Cancer research.

[38]  E. Ringelstein,et al.  Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia: a study in green fluorescent protein transgenic bone marrow chimeric mice , 2003, Experimental Neurology.

[39]  Kazuaki Nakane,et al.  Homology-based method for detecting regions of interest in colonic digital images , 2015, Diagnostic Pathology.

[40]  T. Furuyama,et al.  Effect of Sema4D on microglial function in middle cerebral artery occlusion mice , 2015, Glia.

[41]  Reduction of microglial activity in a model of multiple sclerosis by dipyridamole , 2013, Journal of Neuroinflammation.

[42]  M. O’Banion,et al.  Neuroinflammation and M2 microglia: the good, the bad, and the inflamed , 2014, Journal of Neuroinflammation.

[43]  Shengxiang Zhang,et al.  Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. , 2013, Brain : a journal of neurology.

[44]  D. Simmons,et al.  Molecular cloning of CD68, a human macrophage marker related to lysosomal glycoproteins. , 1993, Blood.

[45]  O. Hurtado,et al.  Role of nitric oxide after brain ischaemia. , 2004, Cell calcium.

[46]  Y. Imai,et al.  Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia. , 2000, Journal of cell science.

[47]  Kazuaki Nakane,et al.  Application of the homology method for quantification of low-attenuation lung region inpatients with and without COPD , 2016, International journal of chronic obstructive pulmonary disease.

[48]  J. Julien,et al.  Ablation of Proliferating Cells in the CNS Exacerbates Motor Neuron Disease Caused by Mutant Superoxide Dismutase , 2012, PloS one.

[49]  W. Paulus,et al.  Distribution and characterization of microglia/macrophages in human brain tumors , 1996, Acta Neuropathologica.