Automatic estimation of the noise variance from the histogram of a magnetic resonance image

Estimation of the noise variance of a magnetic resonance (MR) image is important for various post-processing tasks. In the literature, various methods for noise variance estimation from MR images are available, most of which however require user interaction and/or multiple (perfectly aligned) images. In this paper, we focus on automatic histogram-based noise variance estimation techniques. Previously described methods are reviewed and a new method based on the maximum likelihood (ML) principle is presented. Using Monte Carlo simulation experiments as well as experimental MR data sets, the noise variance estimation methods are compared in terms of the root mean squared error (RMSE). The results show that the newly proposed method is superior in terms of the RMSE.

[1]  R. Fisher The Advanced Theory of Statistics , 1943, Nature.

[2]  J. Wolfowitz,et al.  Introduction to the Theory of Statistics. , 1951 .

[3]  P. H. Sydenham,et al.  Handbook of measurement science , 1982 .

[4]  M. Bronskill,et al.  Noise and filtration in magnetic resonance imaging. , 1985, Medical physics.

[5]  R. Henkelman Measurement of signal intensities in the presence of noise in MR images. , 1985, Medical physics.

[6]  S. Holland MRI: Acceptance testing and quality control—The role of the clinical medical physicist , 1989 .

[7]  D. Ortendahl,et al.  Measuring signal-to-noise ratios in MR imaging. , 1989, Radiology.

[8]  Russell M. Mersereau,et al.  Automatic Detection of Brain Contours in MRI Data Sets , 1991, IPMI.

[9]  B. Murphy,et al.  Signal-to-noise measures for magnetic resonance imagers. , 1993, Magnetic Resonance Imaging.

[10]  M. Smith,et al.  An unbiased signal-to-noise ratio measure for magnetic resonance images. , 1993, Medical physics.

[11]  H. Gudbjartsson,et al.  The rician distribution of noisy mri data , 1995, Magnetic resonance in medicine.

[12]  P. Scheunders,et al.  Quantification and improvement of the signal-to-noise ratio in a magnetic resonance image acquisition procedure. , 1996, Magnetic resonance imaging.

[13]  Alan C. Evans,et al.  BrainWeb: Online Interface to a 3D MRI Simulated Brain Database , 1997 .

[14]  J Sijbers,et al.  Estimation of the noise in magnitude MR images. , 1998, Magnetic resonance imaging.

[15]  Geert M. P. van Kempen,et al.  Influence of background estimation on the superresolution properties of nonlinear image restoration algorithms , 1999 .

[16]  Jan Sijbers,et al.  Parameter estimation from magnitude MR images , 1999, Int. J. Imaging Syst. Technol..

[17]  Geert M. P. van Kempen,et al.  The influence of the background estimation on the superresolution properties of non-linear image restoration algorithms , 1999 .

[18]  Robert D. Nowak,et al.  Wavelet-based Rician noise removal for magnetic resonance imaging , 1999, IEEE Trans. Image Process..

[19]  O. A. Ahmed New denoising scheme for magnetic resonance spectroscopy signals , 2001, 2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[20]  Stephen M. Smith,et al.  Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm , 2001, IEEE Transactions on Medical Imaging.

[21]  Fabrice Heitz,et al.  Automatic change detection in multimodal serial MRI: application to multiple sclerosis lesion evolution , 2003, NeuroImage.

[22]  Julian Stander,et al.  Bayesian analysis of dynamic magnetic resonance breast images , 2004 .

[23]  Carlo Pierpaoli,et al.  Estimating intensity variance due to noise in registered images , 2005, SPIE Medical Imaging.

[24]  Carlo Pierpaoli,et al.  Estimating intensity variance due to noise in registered images: Applications to diffusion tensor MRI , 2005, NeuroImage.

[25]  B. Whitcher,et al.  Multiple hypothesis mapping of functional MRI data in orthogonal and complex wavelet domains , 2005, IEEE Transactions on Signal Processing.

[26]  Luigi Landini,et al.  Advanced Image Processing in Magnetic Resonance Imaging , 2005 .

[27]  Carlo Pierpaoli,et al.  An automatic method for estimating noise-induced signal variance in magnitude-reconstructed magnetic resonance images , 2005, SPIE Medical Imaging.

[28]  Osama A. Ahmed,et al.  New denoising scheme for magnetic resonance spectroscopy signals , 2005, IEEE Transactions on Medical Imaging.

[29]  K. Straughan,et al.  Information in magnetic resonance images: evaluation of signal, noise and contrast , 2006, Medical and Biological Engineering and Computing.