Outcomes of pulmonary rehabilitation after lung resection in patients with lung cancer

Background In this study, we aimed to examine the effectiveness of pulmonary rehabilitation applied after resection in patients with lung cancer. Methods Between October 2017 and December 2019, a total of 66 patients (53 males, 13 females; median age: 65 years; range, 58 to 70 years) who underwent lung resection for non-small cell lung cancer and who were not administered any chemotherapy or radiotherapy regimen were included in the study. An eight-week comprehensive outpatient pulmonary rehabilitation program was applied to half of the patients, while the other half received respiratory exercise training. After the intervention, the results of both groups were compared. Results In the pulmonary rehabilitation group, forced vital capacity value (p=0.011), six-minute walking distance (p<0.001), and Short Form-36 physical function, mental health, vitality scores increased significantly, while all scores of St. George's Respiratory Questionnaire, dyspnea (p<0.001) and anxiety score (p=0.041) significantly decreased. In the group given breathing exercise training, only dyspnea (p=0.046) and St. George's Respiratory Questionnaire symptom scores (p=0.038) were decreased. When the changes in the groups after pulmonary rehabilitation were compared, the decrease in dyspnea perception was significantly higher in the pulmonary rehabilitation group (p<0.001). Conclusion Pulmonary rehabilitation program applied after lung resection in patients with non-small cell lung cancer reduces dyspnea and psychological symptoms, increases exercise capacity, and improves quality of life. It should be ensured that patients with lung cancer who have undergone lung resection are directed to the pulmonary rehabilitation program and benefit from this program.

[1]  B. Naidu,et al.  The key questions in rehabilitation in thoracic surgery. , 2018, Journal of thoracic disease.

[2]  J. de Vries,et al.  Psychosocial consequences of diagnosis and treatment of lung cancer and evaluation of the need for a lung cancer specific instrument using focus group methodology , 2018, Supportive Care in Cancer.

[3]  J. Varga,et al.  Effectiveness of pulmonary rehabilitation and correlations in between functional parameters, extent of thoracic surgery and severity of post-operative complications: randomized clinical trial. , 2018, Journal of thoracic disease.

[4]  H. Lee,et al.  Prehabilitation and rehabilitation for surgically treated lung cancer patients , 2017 .

[5]  Y. Shimada,et al.  Impact of pulmonary rehabilitation on postoperative complications in patients with lung cancer and chronic obstructive pulmonary disease , 2017, Thoracic cancer.

[6]  Y. Shin,et al.  Efficacy of Systemic Postoperative Pulmonary Rehabilitation After Lung Resection Surgery , 2015, Annals of rehabilitation medicine.

[7]  P. Nana-Sinkam,et al.  Integrating pulmonary rehabilitation into the multidisciplinary management of lung cancer: a review. , 2015, Respiratory medicine.

[8]  M. Spruit,et al.  How to adapt the pulmonary rehabilitation programme to patients with chronic respiratory disease other than COPD , 2013, European Respiratory Review.

[9]  A. Yorgancioglu,et al.  [Validity and reliability of Turkish version of St. George's respiratory questionnaire]. , 2013, Tuberkuloz ve toraks.

[10]  K. Taniyama,et al.  Multidisciplinary Team-Based Approach for Comprehensive Preoperative Pulmonary Rehabilitation Including Intensive Nutritional Support for Lung Cancer Patients , 2013, PloS one.

[11]  H. Groen,et al.  A Randomized Controlled Trial of Postthoracotomy Pulmonary Rehabilitation in Patients with Resectable Lung Cancer , 2013, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[12]  Ying-Li Pan,et al.  Breathing exercises improve post-operative pulmonary function and quality of life in patients with lung cancer: A meta-analysis , 2013, Experimental and therapeutic medicine.

[13]  U. Sartipy,et al.  Long-term health-related quality of life following surgery for lung cancer. , 2012, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[14]  L. Tanoue,et al.  Lung cancer: epidemiology, etiology, and prevention. , 2011, Clinics in chest medicine.

[15]  D. Galetta,et al.  Post-operative respiratory rehabilitation after lung resection for non-small cell lung cancer. , 2007, Lung cancer.

[16]  E. Wouters,et al.  Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study. , 2006, Lung cancer.

[17]  J. Nazarian Cardiopulmonary rehabilitation after treatment for lung cancer , 2004, Current treatment options in oncology.

[18]  ATS Statement , 2002 .

[19]  ATS statement: guidelines for the six-minute walk test. , 2002, American journal of respiratory and critical care medicine.

[20]  R. A’Hern,et al.  Multicentre randomised controlled trial of nursing intervention for breathlessness in patients with lung cancer. , 1999, BMJ.

[21]  C. Zwillich,et al.  Dyspnea in the patient with chronic obstructive pulmonary disease. Etiology and management. , 1990, Clinics in chest medicine.

[22]  G. Borg Psychophysical bases of perceived exertion. , 1982, Medicine and science in sports and exercise.

[23]  C. Dolea,et al.  World Health Organization , 1949, International Organization.