Ultrasonographic features of aggressive primary thyroid diffuse B-cell lymphoma: A report of two cases.

Primary thyroid lymphoma (PTL) is a relatively rare malignant tumor. Aggressive PTL is extremely rare, and there is limited literature regarding the imaging features of PTL with invasion into adjacent structures, including internal jugular vein, muscles, esophagus, trachea and carotid artery. In addition, the ultrasonographic features of the cases presented in the current report differ from those reported in previous studies. In the present study, two cases of PTL, who presented to The First Affiliated Hospital of Wannan Medical College (Wuhu, China) with a short history of a rapidly growing mass in the front of their neck, are reported. Both patients had undergone ultrasound examination, and the subsequent histopathological and immunohistochemical examinations confirmed that the two masses were primary diffuse large B-cell lymphoma. The ultrasonographic findings of these two cases are discussed in the present report.

[1]  Ying Xiao,et al.  Primary Thyroid Lymphoma Has Different Sonographic and Color Doppler Features Compared to Nodular Goiter , 2015, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[2]  Yu-xin Jiang,et al.  Sonographic Appearance of Primary Thyroid Lymphoma-Preliminary Experience , 2014, PloS one.

[3]  V. D. Di Crescenzo,et al.  Early cytological diagnosis of extranodal stage I, primary thyroid Non-Hodgkin lymphoma in elderly patients. Report of two cases and review of the literature , 2013, BMC Surgery.

[4]  E. McDermott,et al.  Thyroid lymphoma: recent advances in diagnosis and optimal management strategies. , 2013, The oncologist.

[5]  Eun Sook Ko,et al.  Thyroid Lymphoma , 2012, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[6]  Hiroshi Honda,et al.  Impact of FDG-PET/CT in the management of lymphoma , 2011, Annals of nuclear medicine.

[7]  S. Roman,et al.  Prognosis of primary thyroid lymphoma: demographic, clinical, and pathologic predictors of survival in 1,408 cases. , 2009, Surgery.

[8]  Min Jung Kim,et al.  Primary Thyroid Lymphoma , 2007, Journal of ultrasound in medicine.

[9]  A. Miyauchi,et al.  Usefulness of ultrasonography for diagnosis of malignant lymphoma of the thyroid. , 2006, Thyroid : official journal of the American Thyroid Association.

[10]  Sung In Cho,et al.  High incidence of mucosa-associated lymphoid tissue in primary thyroid lymphoma: A clinicopathologic study of 18 casesin the Korean population , 2006, Leukemia & lymphoma.

[11]  S. Takashima,et al.  Primary Thyroid Lymphoma: Evaluation with US, CT, and MRI , 1995, Journal of computer assisted tomography.

[12]  K. Aozasa Hashimoto's Thyroiditis as a Risk Factor of Thyroid Lymphoma , 1990, Acta pathologica japonica.

[13]  Z. Ye,et al.  Primary thyroid lymphoma: multi-slice computed tomography findings. , 2015, Asian Pacific journal of cancer prevention : APJCP.

[14]  Y. Shibamoto,et al.  Non-Hodgkin's lymphoma of the thyroid. A clinical study of twenty-two cases. , 1996, Acta oncologica.