Fine-needle aspiration of palpable breast masses. A program for staged implementation.

Fine-needle aspiration (FNA) can provide a morphologic diagnosis of palpable breast masses in an accurate, efficient, inexpensive, and safe manner. However, how one acquires the skill to perform the FNA and interpret the resulting smears, while protecting the patient from the risk of false-positive or false-negative results, is scarcely considered. We used a three-phase program to acquire experience with FNA while providing services for 205 patients over a 16-month period. We performed FNA sequentially in vitro, in vivo, and finally in vivo for clinical use. With available literature and this graduated implementation program, physicians totally inexperienced with FNA can achieve results similar to those of medical centers having experience with thousands of patients.

[1]  A. C. Carter,et al.  Breast self‐examination, relationship to stage of breast cancer at diagnosis , 1981, Cancer.

[2]  Kline Ts,et al.  Masquerades of malignancy: a review of 4,241 aspirates from the breast. , 1981 .

[3]  C. Huguley,et al.  The value of breast self‐examination , 1981, Cancer.

[4]  I. Fentiman,et al.  Value of needle biopsy in outpatient diagnosis of breast cancer. , 1980, Archives of surgery.

[5]  T. Kline,et al.  Fine‐needle aspiration of the breast: Diagnoses and pitfalls. A review of 3545 cases , 1979, Cancer.

[6]  A. Cuschieri,et al.  Needle aspiration of the breast with immediate reporting of material. , 1979, British medical journal.

[7]  L. Koss Thin needle aspiration biopsy of endocrine organs. , 1979, Annals of clinical and laboratory science.

[8]  C. Fox INNOVATION IN MEDICAL DIAGNOSIS—THE SCANDINAVIAN CURIOSITY , 1979, The Lancet.

[9]  W. H. Kern,et al.  The diagnosis of breast cancer by fine-needle aspiration smears. , 1979, JAMA.

[10]  J. Wittenberg,et al.  Malignant seeding of the tract after thin-needle aspiration biopsy. , 1979, Radiology.

[11]  Wilson Sl,et al.  The cytologic diagnosis of breast aspirations. , 1978 .

[12]  M. Coel,et al.  Safety of percutaneous fine-needle pancreatic biopsy: a porcine model. , 1978, Investigative radiology.

[13]  B. Rush,et al.  Changing attitudes in the management of cancer of the breast. , 1978, Surgery.

[14]  R. Blamey,et al.  A comparison of the use of the ‘Tru‐Cut’ needle and fine needle aspiration cytology in the pre‐operative diagnosis of carcinoma of the breast , 1978, Histopathology.

[15]  L. Tao,et al.  Fine needle aspiration biopsy of malignant lesions in and around the pancreas , 1978, Cancer.

[16]  G. Kreuzer Aspiration biopsy cytology in proliferating benign mammary dysplasia. , 1978, Acta cytologica.

[17]  P P Rosen,et al.  Frozen Section Diagnosis of Breast Lesions: Recent Experience with 556 Consecutive Biopsies , 1978, Annals of surgery.

[18]  J. Zajicek Aspiration biopsy cytology. , 1977, Lymphology.

[19]  A. Wallgren,et al.  Cytologic presentation of mammary carcinoma on aspiration biopsy smears. , 1976, Acta cytologica.

[20]  J. Zajicek,et al.  Implantation Metastasis after Percutaneous Transthoracic Needle Aspiration Biopsy , 1976, Acta radiologica: diagnosis.

[21]  G. Kreuzer,et al.  Aspiration biopsy cytology, mammography and clinical exploration: a modern set up in diagnosis of tumors of the breast. , 1976, Acta cytologica.

[22]  W. Frable Thin-needle aspiration biopsy. A personal experience with 469 cases. , 1976, American journal of clinical pathology.

[23]  George Wd,et al.  Drill biopsy in the diagnosis of breast cancer. , 1975 .

[24]  M. Baum,et al.  The 'tru-cut' biopsy in breast cancer. , 1975, Clinical oncology.

[25]  B. Stenkvist,et al.  The diagnostic accuracy of palpation and fine-needle biopsy and an evaluation of their combined use in the diagnosis of breast lesions: report on a prospective study in 1244 women with symptoms. , 1975, Annals of surgery.

[26]  S. Desai,et al.  Needle aspiration of palpable breast lesions: a new application of the membrane filter technique and its results. , 1975, Clinical oncology.

[27]  A. Zajdela,et al.  The value of aspiration cytology in the diagnosis of breast cancer: Experience at the fondation curie , 1975, Cancer.

[28]  L. Schour,et al.  Fine needle aspiration in the management of patients with neoplastic disease. , 1974, Acta cytologica.

[29]  W. Holaday,et al.  Ten thousand consecutive frozen sections. A retrospective study focusing on accuracy and quality control. , 1974, American journal of clinical pathology.

[30]  A. Patchefsky,et al.  Increased detection of occult breast carcinoma after more thorough histologic examination of breast biopsies. , 1973, American journal of clinical pathology.

[31]  M. Melamed,et al.  The diagnostic value of aspiration smears. , 1973, American journal of clinical pathology.

[32]  J. Zajicek,et al.  Cytologic diagnosis of mammary tumors from aspiration biopsy smears. 3. Studies on 200 carcinomas with false negative or doubtful cytologic reports. , 1972, Acta cytologica.

[33]  J. Zajicek,et al.  Cytologic diagnosis of mammary tumors from aspiration biopsy smears. II. Studies on 210 fibroadenomas and 210 cases of benign dysplasia. , 1972, Acta cytologica.

[34]  D. Gb,et al.  The cytopathology of hyperplastic and neoplastic mammary duct epithelium. Cytologic and ultrastructural studies. , 1972 .

[35]  P. Esposti,et al.  Investigation on tumour spread in connection with aspiration biopsy. , 1971, Acta radiologica: therapy, physics, biology.

[36]  G. Robbins,et al.  A late look at the safety of aspiration biopsy , 1962, Cancer.

[37]  R. Sparkman Reliability of frozen sections in the diagnosis of breast lesions. , 1962, Annals of surgery.

[38]  Mcclellan Jt,et al.  An analysis of 1500 breast biopsies. , 1960, The American surgeon.

[39]  G. Robbins,et al.  Is aspiration biopsy of breast cancer dangerous to the patient? , 1954, Cancer.

[40]  Storrs Hg The role of excision biopsy in lesions of the breast. , 1952 .

[41]  H. Strawbridge,et al.  Role of cytology in management of lesions of the breast. , 1981, Surgery, gynecology & obstetrics.

[42]  Koss Lg Thin needle aspiration biopsy. , 1980 .

[43]  H. Schöndorf,et al.  Aspiration cytology of the breast , 1978 .

[44]  R. Galen,et al.  Beyond Normality: The Predictive Value and E ciency of Medical Diagnoses , 1975 .

[45]  J. Zajicek,et al.  Aspiration biopsy of metastatic carcinoma in lymph nodes of the neck. A review of 1101 consecutive cases. , 1971, Acta oto-laryngologica.

[46]  J. Zajicek,et al.  Aspiration biopsy in diagnosis of palpable lesions of the breast. Critical review of 3479 consecutive biopsies. , 1968, Acta radiologica: therapy, physics, biology.

[47]  R. Lattes,et al.  Frozen section experience in 3000 cases. Accuracy, limitations, and value in residency training. , 1968, American journal of clinical pathology.

[48]  N. Wikstad,et al.  Renal adenocarcinoma. Is there a risk of spreading tumour cells in diagnostic puncture? , 1967, Scandinavian journal of urology and nephrology.