Role of a distal enhancer in the transcriptional responsiveness of the human CD200 gene to interferon-gamma and tumor necrosis factor-alpha.

[1]  N. Sharpless,et al.  CD200 is induced by ERK and is a potential therapeutic target in melanoma. , 2007, The Journal of clinical investigation.

[2]  R. Gorczynski,et al.  Mice Lacking CD200R1 Show Absence of Suppression of Lipopolysaccharide-Induced Tumor Necrosis Factor-&agr; and Mixed Leukocyte Culture Responses by CD200 , 2007, Transplantation.

[3]  R. Bronson,et al.  Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration. , 2007, The American journal of pathology.

[4]  J. Mcwhirter,et al.  CD200 Expression on Tumor Cells Suppresses Antitumor Immunity: New Approaches to Cancer Immunotherapy , 2007, The Journal of Immunology.

[5]  K. Honda,et al.  IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors , 2006, Nature Reviews Immunology.

[6]  P. Marsden,et al.  Cloning and characterization of the human CD200 promoter region. , 2006, Molecular immunology.

[7]  A. Saven,et al.  Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[8]  D. Geller,et al.  Differential Effects of TNF-α and IFN-γ on Gene Transcription Mediated by NF-κB-Stat1 Interactions , 2005 .

[9]  L. Tora,et al.  The role of enhancers as centres for general transcription factor recruitment. , 2005, Trends in biochemical sciences.

[10]  J. Fish,et al.  The Expression of Endothelial Nitric-oxide Synthase Is Controlled by a Cell-specific Histone Code* , 2005, Journal of Biological Chemistry.

[11]  W. Bessler,et al.  Characterization of an interaction between fetal hemoglobin and lipid A of LPS resulting in augmented induction of cytokine production in vivo and in vitro. , 2004, International immunopharmacology.

[12]  M. Rosenblum,et al.  Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance? , 2004, The Journal of investigative dermatology.

[13]  J. Fish,et al.  The Cell-specific Expression of Endothelial Nitric-oxide Synthase , 2004, Journal of Biological Chemistry.

[14]  A. Langerak,et al.  Regulation of MHC class II expression in human T-cell malignancies. , 2004, Blood.

[15]  K. Schroder,et al.  Interferon‐γ: an overview of signals, mechanisms and functions , 2004 .

[16]  Joseph H. Phillips,et al.  Characterization of the CD200 Receptor Family in Mice and Humans and Their Interactions with CD200 1 , 2003, The Journal of Immunology.

[17]  Wei Xu,et al.  Androgen-induced recruitment of RNA polymerase II to a nuclear receptor–p160 coactivator complex , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[18]  J. Forrester,et al.  Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis. , 2002, The American journal of pathology.

[19]  R. Gorczynski,et al.  The Same Immunoregulatory Molecules Contribute to Successful Pregnancy and Transplantation , 2002, American journal of reproductive immunology.

[20]  A. Barclay,et al.  CD200 and membrane protein interactions in the control of myeloid cells. , 2002, Trends in immunology.

[21]  D. Goeddel,et al.  TNF-R1 Signaling: A Beautiful Pathway , 2002, Science.

[22]  Y. Shang,et al.  Formation of the androgen receptor transcription complex. , 2002, Molecular cell.

[23]  P. Farnham,et al.  Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. , 2002, Methods.

[24]  R. Gorczynski,et al.  CD200 immunoadhesin suppresses collagen-induced arthritis in mice. , 2001, Clinical immunology.

[25]  R. Gorczynski,et al.  Evidence of a role for CD200 in regulation of immune rejection of leukaemic tumour cells in C57BL/6 mice , 2001, Clinical and experimental immunology.

[26]  B. Blom,et al.  Down-regulation of the macrophage lineage through interaction with OX2 (CD200). , 2000, Science.

[27]  S. Paludan.  Synergistic action of pro‐inflammatory agents: cellular and molecular aspects , 2000, Journal of leukocyte biology.

[28]  G. Yu,et al.  An immunoadhesin incorporating the molecule OX-2 is a potent immunosuppressant that prolongs allo- and xenograft survival. , 1999, Journal of immunology.

[29]  Yang Wang,et al.  Characterization of the Human Endothelial Nitric-oxide Synthase Promoter* , 1999, The Journal of Biological Chemistry.

[30]  R. Gorczynski,et al.  Evidence that an OX-2-positive cell can inhibit the stimulation of type 1 cytokine production by bone marrow-derived B7-1 (and B7-2)-positive dendritic cells. , 1999, Journal of immunology.

[31]  S. Majumder,et al.  p48/STAT-1α-Containing Complexes Play a Predominant Role in Induction of IFN-γ-Inducible Protein, 10 kDa (IP-10) by IFN-γ Alone or in Synergy with TNF-α , 1998, Journal of Immunology.

[32]  L. Pfeffer,et al.  STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activities. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[33]  R. Gorczynski,et al.  Increased expression of the novel molecule OX-2 is involved in prolongation of murine renal allograft survival. , 1998, Transplantation.

[34]  R. Gorczynski,et al.  Cloning and characterization of the murine homologue of the rat/human MRC OX-2 gene. , 1997, Biochimica et biophysica acta.

[35]  A. Means,et al.  Organization and Analysis of the Complete Rat Calmodulin- dependent Protein Kinase IV Gene * , 1995, The Journal of Biological Chemistry.

[36]  J. Pober,et al.  HLA class I heavy-chain gene promoter elements mediating synergy between tumor necrosis factor and interferons. , 1994, Molecular and cellular biology.

[37]  A. Deisseroth,et al.  A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter , 1993, Molecular and cellular biology.

[38]  J. Pober,et al.  IFN-gamma enhances endothelial activation induced by tumor necrosis factor but not IL-1. , 1990, Journal of immunology.

[39]  A. Barclay,et al.  Purification and chemical characterisation of membrane glycoproteins from rat thymocytes and brain, recognised by monoclonal antibody MRC OX 2. , 1982, European journal of biochemistry.

[40]  A. Barclay.  Different reticular elements in rat lymphoid tissue identified by localization of Ia, Thy-1 and MRC OX 2 antigens. , 1981, Immunology.

[41]  Zheng‐gang Liu,et al.  Molecular mechanism of TNF signaling and beyond , 2005, Cell Research.

[42]  F. Grosveld,et al.  The gene for MRC OX-2 membrane glycoprotein is localized on human chromosome 3 , 2004, Immunogenetics.

[43]  D. S. Gross,et al.  Nuclease hypersensitive sites in chromatin. , 1988, Annual review of biochemistry.