Dosimetry for a microbeam array generated by synchrotron radiation at SPring-8.

A microbeam array was formed with a multi-slit collimator (MSC) for research on radiation therapy (MRT). Kodak EDR2 film was used to measure the dose distribution of the microbeam array. The calibration curve of optical density of the film with respect to a dose was established using a standard Farmer chamber and (60)Co gamma-ray source. The peak dose of 3.6 Gy/s at the maximum was derived from the film dosimetry using the calibration curve. The uncertainty was estimated to be 5% which was mainly attributed to the uncertainty of the calibration. It was found that the ionization chamber used for monitoring the dose during the MRT experiments gave lower dose by about 30% than the dose derived from the film dosimetry.

[1]  Chengyu Shi,et al.  Analysis of the sources of uncertainty for EDR2 film‐based IMRT quality assurance , 2006, Journal of applied clinical medical physics.

[2]  H. Blattmann,et al.  Erratum: “Characterization of a tungsten/gas multislit collimator (TMSC) for microbeam radiation therapy at the European Synchrotron Radiation Facility”[Rev. Sci. Instrum. 76, 064303 (2005)] , 2006 .

[3]  B. Bjärngard,et al.  Doses on the central axes of narrow 6-MV x-ray beams. , 1990, Medical physics.

[4]  R. Nath,et al.  Photon energy dependence of the sensitivity of radiochromic film and comparison with silver halide film and LiF TLDs used for brachytherapy dosimetry. , 1991, Medical physics.

[5]  J. Dempsey,et al.  TG-69: radiographic film for megavoltage beam dosimetry. , 2007, Medical physics.

[6]  H. Kitamura,et al.  SPECTRA: a synchrotron radiation calculation code. , 2001, Journal of synchrotron radiation.

[7]  H. Blattmann,et al.  Characterization of a tungsten/gas multislit collimator for microbeam radiation therapy at the European Synchrotron Radiation Facility , 2005 .

[8]  B. Clark,et al.  The use of radiographic film for linear accelerator stereotactic radiosurgical dosimetry. , 1999, Medical physics.

[9]  Takashi NAKAMURA,et al.  Development of General-Purpose Particle and Heavy Ion Transport Monte Carlo Code , 2002 .

[10]  M. Di Michiel,et al.  MOSFET dosimetry for microbeam radiation therapy at the European Synchrotron Radiation Facility. , 2003, Medical physics.