Regulation of inflammasomes by autophagy.

[1]  N. Ktistakis,et al.  Digesting the Expanding Mechanisms of Autophagy. , 2016, Trends in cell biology.

[2]  Mark Ellisman,et al.  NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria , 2016, Cell.

[3]  Shuzhao Li,et al.  The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation , 2016, Nature.

[4]  Sangeeta Khare,et al.  Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition) , 2016 .

[5]  C. Behl,et al.  Ubiquitin-Dependent And Independent Signals In Selective Autophagy. , 2016, Trends in cell biology.

[6]  Si Ming Man,et al.  Converging roles of caspases in inflammasome activation, cell death and innate immunity , 2015, Nature Reviews Immunology.

[7]  T. Saitoh,et al.  Autophagy and autophagy-related proteins in the immune system , 2015, Nature Immunology.

[8]  Denise N. Bronner,et al.  Endoplasmic Reticulum stress activates the inflammasome via NLRP 3-caspase-2 driven mitochondrial damage , 2015 .

[9]  B. Friguet,et al.  Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet , 2015, Circulation.

[10]  S. Koo,et al.  Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes , 2014, Nature Communications.

[11]  Myung-Shik Lee,et al.  Autophagy—a key player in cellular and body metabolism , 2014, Nature Reviews Endocrinology.

[12]  Vishva M. Dixit,et al.  Mechanisms and Functions of Inflammasomes , 2014, Cell.

[13]  D. Bumann,et al.  Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases , 2014, Nature.

[14]  Jacob D. Jaffe,et al.  Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense , 2014, Proceedings of the National Academy of Sciences.

[15]  Qiang Xu,et al.  Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer , 2014, Autophagy.

[16]  J. DeVoss,et al.  A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3 , 2014, Nature.

[17]  B. Oh,et al.  Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses. , 2014, Cell host & microbe.

[18]  Y. Ohsumi Historical landmarks of autophagy research , 2013, Cell Research.

[19]  M. Daly,et al.  Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules. , 2013, ACS chemical biology.

[20]  G. Barber,et al.  Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling , 2013, Cell.

[21]  Shizuo Akira,et al.  Autophagy in infection, inflammation and immunity , 2013, Nature Reviews Immunology.

[22]  E. Latz,et al.  Activation and regulation of the inflammasomes , 2013, Nature Reviews Immunology.

[23]  S. Akira,et al.  Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome , 2013, Nature Immunology.

[24]  Paul G. Thomas,et al.  Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection , 2013, Nature Immunology.

[25]  Xian Chen,et al.  The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. , 2012, Immunity.

[26]  M. Kastan,et al.  Autophagy links inflammasomes to atherosclerotic progression. , 2012, Cell metabolism.

[27]  Robert Clarke,et al.  Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .

[28]  A. Sher,et al.  Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction , 2012, Nature Immunology.

[29]  V. Deretic,et al.  Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β , 2011, The EMBO journal.

[30]  Masaaki Komatsu,et al.  Autophagy: Renovation of Cells and Tissues , 2011, Cell.

[31]  Denis Gris,et al.  Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling , 2011, Nature Immunology.

[32]  S. Ryter,et al.  Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. , 2011, Nature immunology.

[33]  J. Tschopp,et al.  A role for mitochondria in NLRP3 inflammasome activation , 2011, Nature.

[34]  J. Tschopp,et al.  Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation , 2011, The Journal of Biological Chemistry.

[35]  R. Xavier,et al.  Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine , 2010, Cell.

[36]  S. Akira,et al.  Pattern Recognition Receptors and Inflammation , 2010, Cell.

[37]  K. Ishii,et al.  Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response , 2009, Proceedings of the National Academy of Sciences.

[38]  Yoshiaki Kamada,et al.  Dynamics and diversity in autophagy mechanisms: lessons from yeast , 2009, Nature Reviews Molecular Cell Biology.

[39]  Shizuo Akira,et al.  The roles of TLRs, RLRs and NLRs in pathogen recognition. , 2009, International immunology.

[40]  A. Iwasaki,et al.  Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling , 2009, Proceedings of the National Academy of Sciences.

[41]  S. Akira,et al.  Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production , 2008, Nature.

[42]  Sarah L. Brown,et al.  A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells , 2008, Nature.

[43]  K. Rock,et al.  Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization , 2008, Nature Immunology.

[44]  J. Tschopp,et al.  Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica , 2008, Science.

[45]  D. Green,et al.  Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis , 2007, Nature.

[46]  A. Miyawaki,et al.  The Atg5–Atg12 conjugate associates with innate antiviral immune responses , 2007, Proceedings of the National Academy of Sciences.

[47]  A. Sharafkhaneh,et al.  Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. , 2007, Immunity.

[48]  Judy H Cho,et al.  Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis , 2007, Nature Genetics.

[49]  A. Iwasaki,et al.  In Brief , 2007, Nature Reviews Immunology.

[50]  Thomas Lengauer,et al.  A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 , 2007, Nature Genetics.

[51]  A. Novikoff,et al.  The Proximal Tubule Cell in Experimental Hydronephrosis , 1959, The Journal of biophysical and biochemical cytology.

[52]  S. L. Clark CELLULAR DIFFERENTIATION IN THE KIDNEYS OF NEWBORN MICE STUDIED WITH THE ELECTRON MICROSCOPE , 1957, The Journal of biophysical and biochemical cytology.