The case for myocardial ischemia in hypertrophic cardiomyopathy.

[1]  Warren J Manning,et al.  Clinical Profile and Significance of Delayed Enhancement in Hypertrophic Cardiomyopathy , 2008, Circulation. Heart failure.

[2]  A. Pupi,et al.  Spatial Relationship Between Coronary Microvascular Dysfunction and Delayed Contrast Enhancement in Patients with Hypertrophic Cardiomyopathy , 2008, Journal of Nuclear Medicine.

[3]  P. Serruys,et al.  Effect of successful alcohol septal ablation on microvascular function in patients with obstructive hypertrophic cardiomyopathy. , 2008, The American journal of cardiology.

[4]  W. Manning,et al.  Occurrence and frequency of arrhythmias in hypertrophic cardiomyopathy in relation to delayed enhancement on cardiovascular magnetic resonance. , 2008, Journal of the American College of Cardiology.

[5]  W. Roberts,et al.  Sudden cardiac arrest in hypertrophic cardiomyopathy in the absence of conventional criteria for high risk status. , 2008, The American journal of cardiology.

[6]  S. Ommen,et al.  Evaluation of Left Ventricular Filling Pressures by Doppler Echocardiography in Patients With Hypertrophic Cardiomyopathy: Correlation With Direct Left Atrial Pressure Measurement at Cardiac Catheterization , 2007, Circulation.

[7]  J. Seidman,et al.  Genetic Basis of Hypertrophic Cardiomyopathy: From Bench to the Clinics , 2007, Journal of cardiovascular electrophysiology.

[8]  G. Taffet,et al.  Coronary Microvascular Dysfunction , 2007 .

[9]  M. Robson,et al.  Evidence for Microvascular Dysfunction in Hypertrophic Cardiomyopathy: New Insights From Multiparametric Magnetic Resonance Imaging , 2007, Circulation.

[10]  J. Zwanenburg,et al.  Regional heterogeneity of resting perfusion in hypertrophic cardiomyopathy is related to delayed contrast enhancement but not to systolic function: A PET and MRI study , 2006, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

[11]  W. Manning,et al.  Prevalence, Clinical Profile, and Significance of Left Ventricular Remodeling in the End-Stage Phase of Hypertrophic Cardiomyopathy , 2006, Circulation.

[12]  F. Girolami,et al.  Relevance of coronary microvascular flow impairment to long-term remodeling and systolic dysfunction in hypertrophic cardiomyopathy. , 2006, Journal of the American College of Cardiology.

[13]  R. Gibbons,et al.  Prognostic utility of single-photon emission computed tomography in adult patients with hypertrophic cardiomyopathy. , 2006, American heart journal.

[14]  M. Borggrefe,et al.  CMR scarring in a patient with hypertrophic cardiomyopathy correlates well with histological findings of fibrosis. , 2005, European heart journal.

[15]  A. Tajik,et al.  Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy. , 2005, Journal of the American College of Cardiology.

[16]  J. Lima,et al.  Cardiovascular magnetic resonance imaging: current and emerging applications. , 2004, Journal of the American College of Cardiology.

[17]  I. Olivotto,et al.  Coronary microvascular dysfunction and ischemia in hypertrophic cardiomyopathy. Mechanisms and clinical consequences. , 2004, Italian heart journal : official journal of the Italian Federation of Cardiology.

[18]  Dudley J Pennell,et al.  The histologic basis of late gadolinium enhancement cardiovascular magnetic resonance in hypertrophic cardiomyopathy. , 2004, Journal of the American College of Cardiology.

[19]  M. Entman,et al.  Aldosterone, Through Novel Signaling Proteins, Is a Fundamental Molecular Bridge Between the Genetic Defect and the Cardiac Phenotype of Hypertrophic Cardiomyopathy , 2004, Circulation.

[20]  S. Kaul,et al.  Microvasculature in acute myocardial ischemia: part II: evolving concepts in pathophysiology, diagnosis, and treatment. , 2004, Circulation.

[21]  A. Tajik,et al.  Adverse Prognosis of Patients With Hypertrophic Cardiomyopathy Who Have Epicardial Coronary Artery Disease , 2003, Circulation.

[22]  Barry J Maron,et al.  American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice G , 2003, Journal of the American College of Cardiology.

[23]  M. Chiariello,et al.  Myocardial Collagen Turnover in Hypertrophic Cardiomyopathy , 2003, Circulation.

[24]  I. Olivotto,et al.  Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy. , 2003, The New England journal of medicine.

[25]  A. Matsumori,et al.  Measurements of cardiac troponin T in patients with hypertrophic cardiomyopathy , 2003, Heart.

[26]  D. Pennell,et al.  Toward clinical risk assessment in hypertrophic cardiomyopathy with gadolinium cardiovascular magnetic resonance. , 2003, Journal of the American College of Cardiology.

[27]  Raymond J Kim,et al.  Gadolinium-enhanced magnetic resonance imaging in hypertrophic cardiomyopathy: in vivo imaging of the pathologic substrate for premature cardiac death? , 2003, Journal of the American College of Cardiology.

[28]  Dudley J Pennell,et al.  Cardiovascular magnetic resonance: twenty-first century solutions in cardiology. , 2003, Clinical medicine.

[29]  M. Sherrid,et al.  Obstructive hypertrophic cardiomyopathy: echocardiography, pathophysiology, and the continuing evolution of surgery for obstruction. , 2003, The Annals of thoracic surgery.

[30]  B. Maron,et al.  Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. , 2003, The New England journal of medicine.

[31]  Heiko Mahrholdt,et al.  Myocardial scarring in asymptomatic or mildly symptomatic patients with hypertrophic cardiomyopathy. , 2002, Journal of the American College of Cardiology.

[32]  B. Maron.  Hypertrophic cardiomyopathy: a systematic review. , 2002, JAMA.

[33]  D. Pennell,et al.  Mechanisms of Coronary Microcirculatory Dysfunction in Patients With Aortic Stenosis and Angiographically Normal Coronary Arteries , 2002, Circulation.

[34]  T. Miller,et al.  Myocardial ischemia on thallium scintigraphy in hypertrophic cardiomyopathy: predictor of sudden cardiac death. , 2001, Circulation.

[35]  M. Entman,et al.  Angiotensin II Blockade Reverses Myocardial Fibrosis in a Transgenic Mouse Model of Human Hypertrophic Cardiomyopathy , 2001, Circulation.

[36]  P. Elliott,et al.  Sudden death in hypertrophic cardiomyopathy: identification of high risk patients. , 2000, Journal of the American College of Cardiology.

[37]  W J McKenna,et al.  Hypertrophic cardiomyopathy: the interrelation of disarray, fibrosis, and small vessel disease , 2000, Heart.

[38]  B. Maron,et al.  Epidemiology of hypertrophic cardiomyopathy-related death: revisited in a large non-referral-based patient population. , 2000, Circulation.

[39]  G Thiene,et al.  Hypertrophic cardiomyopathy and sudden death in the young: pathologic evidence of myocardial ischemia. , 2000, Human pathology.

[40]  B. Maron,et al.  Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathy. , 2000, The New England journal of medicine.

[41]  G. Thiene,et al.  Myocardial infarction in a patient with hypertrophic cardiomyopathy. , 2000, The New England journal of medicine.

[42]  O. Simonetti,et al.  Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. , 1999, Circulation.

[43]  O. Rimoldi,et al.  Transmural myocardial blood flow distribution in hypertrophic cardiomyopathy and effect of treatment , 1999, Basic Research in Cardiology.

[44]  W. Mckenna,et al.  Coronary vasodilator reserve is impaired in patients with hypertrophic cardiomyopathy and left ventricular dysfunction. , 1998, American heart journal.

[45]  B. Strauer,et al.  Alterations of the architecture of subendocardial arterioles in patients with hypertrophic cardiomyopathy and impaired coronary vasodilator reserve: a possible cause for myocardial ischemia. , 1998, Journal of the American College of Cardiology.

[46]  C. M. Lowe,et al.  Dipyridamole stress thallium-201 perfusion abnormalities in patients with hypertrophic cardiomyopathy. Relationship to clinical presentation and outcome. , 1998, European heart journal.

[47]  P. Serruys,et al.  Decreased coronary flow reserve in hypertrophic cardiomyopathy is related to remodeling of the coronary microcirculation. , 1998, Circulation.

[48]  E. Picano,et al.  Dipyridamole-induced ischemia as a prognostic marker of future adverse cardiac events in adult patients with hypertrophic cardiomyopathy. Echo Persantine Italian Cooperative (EPIC) Study Group, Subproject Hypertrophic Cardiomyopathy. , 1997, Circulation.

[49]  W. Mckenna,et al.  Chest pain during daily life in patients with hypertrophic cardiomyopathy: an ambulatory electrocardiographic study. , 1996, European heart journal.

[50]  P. Poole‐Wilson,et al.  Changes in coronary sinus pH during dipyridamole stress in patients with hypertrophic cardiomyopathy. , 1996, Heart.

[51]  B. Maron,et al.  Hypertrophic cardiomyopathy in Tuscany: clinical course and outcome in an unselected regional population. , 1995, Journal of the American College of Cardiology.

[52]  W. Williams,et al.  Hypertrophic cardiomyopathy. Clinical spectrum and treatment. , 1995, Circulation.

[53]  F. Cecchi,et al.  Effect of verapamil on absolute myocardial blood flow in hypertrophic cardiomyopathy. , 1994, The American journal of cardiology.

[54]  A. Ciarmiello,et al.  Effects of induced asynchrony on left ventricular diastolic function in patients with coronary artery disease. , 1993, Journal of the American College of Cardiology.

[55]  D. O'Gorman,et al.  Abnormalities of the coronary circulation associated with left ventricular hypertrophy. , 1991, Clinical science.

[56]  S. Factor,et al.  Pathologic fibrosis and matrix connective tissue in the subaortic myocardium of patients with hypertrophic cardiomyopathy. , 1991, Journal of the American College of Cardiology.

[57]  A. Quyyumi,et al.  Myocardial Metabolic, Hemodynamic, and Electrocardiographic Significance of Reversible Thallium‐201 Abnormalities in Hypertrophic Cardiomyopathy , 1991, Circulation.

[58]  A. L'Abbate,et al.  Coronary vasodilation is impaired in both hypertrophied and nonhypertrophied myocardium of patients with hypertrophic cardiomyopathy: a study with nitrogen-13 ammonia and positron emission tomography. , 1991, Journal of the American College of Cardiology.

[59]  B. Maron,et al.  Relation between extent of left ventricular hypertrophy and diastolic filling abnormalities in hypertrophic cardiomyopathy. , 1990, Journal of the American College of Cardiology.

[60]  M. Frank,et al.  Significance of positive or negative thallium-201 scintigraphy in hypertrophic cardiomyopathy. , 1989, The American journal of cardiology.

[61]  R. Bonow,et al.  Verapamil prevents silent myocardial perfusion abnormalities during exercise in asymptomatic patients with hypertrophic cardiomyopathy. , 1989, Circulation.

[62]  R. Bonow,et al.  Effect of surgical reduction of left ventricular outflow obstruction on hemodynamics, coronary flow, and myocardial metabolism in hypertrophic cardiomyopathy. , 1989, Circulation.

[63]  M. Phelps,et al.  Regional myocardial blood flow and metabolism at rest in mildly symptomatic patients with hypertrophic cardiomyopathy. , 1989, Journal of the American College of Cardiology.

[64]  S. Larson,et al.  Myocardial perfusion abnormalities in patients with hypertrophic cardiomyopathy: assessment with thallium-201 emission computed tomography. , 1987, Circulation.

[65]  C. Tracy,et al.  Differences in coronary flow and myocardial metabolism at rest and during pacing between patients with obstructive and patients with nonobstructive hypertrophic cardiomyopathy. , 1987, Journal of the American College of Cardiology.

[66]  W. Roberts,et al.  Intramural ("small vessel") coronary artery disease in hypertrophic cardiomyopathy. , 1986, Journal of the American College of Cardiology.

[67]  C Kawai,et al.  Quantitative analysis of myocardial fibrosis in normals, hypertensive hearts, and hypertrophic cardiomyopathy. , 1986, British heart journal.

[68]  Z. Krajcer,et al.  Coronary artery disease in hypertrophic cardiomyopathy. , 1985, The American journal of cardiology.

[69]  R. Bonow,et al.  Myocardial ischemia in patients with hypertrophic cardiomyopathy: contribution of inadequate vasodilator reserve and elevated left ventricular filling pressures. , 1985, Circulation.

[70]  W. Roberts,et al.  Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients. , 1982, Circulation.

[71]  C. Henschke,et al.  Pathophysiology of Chest Pain in Patients with Cardiomyopathies and Normal Coronary Arteries , 1982, Circulation.

[72]  E. Sowton,et al.  Assessment of chest pain in hypertrophic cardiomyopathy using exercise thallium-201 myocardial scintigraphy. , 1980, British heart journal.

[73]  S. Gulotta,et al.  Idiopathic hypertrophic subaortic stenosis: evaluation of anginal symptoms with thallium-201 myocardial imaging. , 1979, The American journal of cardiology.

[74]  W. Roberts,et al.  Hypertrophic cardiomyopathy and transmural myocardial infarction without significant atherosclerosis of the extramural coronary arteries. , 1979, The American journal of cardiology.

[75]  W. Roberts,et al.  Pathologic Anatomy of the Cardiomyopathies , 1975 .

[76]  Hiroshi Ito,et al.  Microvasculature in acute myocardial ischemia: part I: evolving concepts in pathophysiology, diagnosis, and treatment. , 2004, Circulation.

[77]  W. Roberts,et al.  Morphology and significance of the left ventricular collagen network in young patients with hypertrophic cardiomyopathy and sudden cardiac death. , 2000, Journal of the American College of Cardiology.

[78]  P. Nihoyannopoulos,et al.  Coronary vasodilator reserve in primary and secondary left ventricular hypertrophy. A study with positron emission tomography. , 1997, European heart journal.

[79]  W. Roberts,et al.  Pathologic anatomy of the cardiomyopathies. Idiopathic dilated and hypertrophic types, infiltrative types, and endomyocardial disease with and without eosinophilia. , 1975, Human pathology.