Linoleic Acid Decreases Leptin and Adiponectin Secretion from Primary Rat Adipocytes in the Presence of Insulin

[1]  P. Havel Role of adipose tissue in body-weight regulation: mechanisms regulating leptin production and energy balance , 2000, Proceedings of the Nutrition Society.

[2]  T. Funahashi,et al.  Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. , 2001, Diabetes.

[3]  T. Ide,et al.  Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. , 2000, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[4]  M. Moreno-Aliaga,et al.  Effects of Trecadrine, a beta3-adrenergic agonist, on leptin secretion, glucose and lipid metabolism in isolated rat adipocytes. , 2002, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[5]  P. Besnard,et al.  Hyperinsulinaemia triggered by dietary conjugated linoleic acid is associated with a decrease in leptin and adiponectin plasma levels and pancreatic beta cell hyperplasia in the mouse , 2005, Diabetologia.

[6]  E. Kraegen,et al.  Development of Muscle Insulin Resistance After Liver Insulin Resistance in High-Fat–Fed Rats , 1991, Diabetes.

[7]  J. Prins,et al.  Effects of rosiglitazone and linoleic acid on human preadipocyte differentiation , 2003, European Journal of Clinical Investigation.

[8]  G. Bray,et al.  The influence of different fats and fatty acids on obesity, insulin resistance and inflammation. , 2002, The Journal of nutrition.

[9]  A. Dulloo,et al.  Differential effects of high-fat diets varying in fatty acid composition on the efficiency of lean and fat tissue deposition during weight recovery after low food intake. , 1995, Metabolism: clinical and experimental.

[10]  A. Martí,et al.  Leptin: physiological actions. , 1999, Journal of physiology and biochemistry.

[11]  A. Martí,et al.  Conjugated linoleic acid inhibits glucose metabolism, leptin and adiponectin secretion in primary cultured rat adipocytes , 2007, Molecular and Cellular Endocrinology.

[12]  P. J. Jones,et al.  Conjugated linoleic acid and obesity control: efficacy and mechanisms , 2004, International Journal of Obesity.

[13]  Koji Yamada,et al.  Modulation of body fat and serum leptin levels by dietary conjugated linoleic acid in Sprague-Dawley rats fed various fat-level diets. , 2003, Nutrition.

[14]  P. Legrand,et al.  Temporal changes in dietary fats: role of n-6 polyunsaturated fatty acids in excessive adipose tissue development and relationship to obesity. , 2006, Progress in lipid research.

[15]  C. Kahn,et al.  Insulin action and the insulin signaling network. , 1995, Endocrine reviews.

[16]  R. Paschke,et al.  Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. , 2002, Biochemical and biophysical research communications.

[17]  A. Martí,et al.  Eicosapentaenoic fatty acid increases leptin secretion from primary cultured rat adipocytes: role of glucose metabolism. , 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

[18]  M. Rodríguez-Cruz,et al.  [Molecular mechanisms of action and health benefits of polyunsaturated fatty acids]. , 2005, Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion.

[19]  J. H. Law,et al.  Kinetic analysis of the action of soybean lipoxygenase on linoleic acid. , 1976, The Journal of biological chemistry.

[20]  M. Moreno-Aliaga,et al.  Transcriptional regulation of the leptin promoter by insulin-stimulated glucose metabolism in 3t3-l1 adipocytes. , 2001, Biochemical and biophysical research communications.

[21]  F. García-Carmona,et al.  Use of 'soluble lipids' for biochemical processes: linoleic acid-cyclodextrin inclusion complexes in aqueous solutions. , 1995, The Biochemical journal.

[22]  Y. Shimomura,et al.  Less body fat accumulation in rats fed a safflower oil diet than in rats fed a beef tallow diet. , 1990, The Journal of nutrition.

[23]  B. Cheatham,et al.  Regulation of ob gene expression and leptin secretion by insulin and dexamethasone in rat adipocytes. , 1999, Diabetes.

[24]  T. Funahashi,et al.  Plasma adiponectin concentrations in children: relationships with obesity and insulinemia. , 2002, The Journal of clinical endocrinology and metabolism.

[25]  M. Cnop,et al.  Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex , 2003, Diabetologia.

[26]  高橋 陽子 Dietary n-3 fatty acids affect mRNA level of brown adipose tissue uncoupling protein 1,and white adipose tissue leptin and glucose transporter 4 in the rat , 2000 .

[27]  R. Giacco,et al.  Dietary fat, insulin sensitivity and the metabolic syndrome. , 2004, Clinical nutrition.

[28]  M. Quon,et al.  Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes. , 2004, Molecular endocrinology.

[29]  M. Pariza,et al.  trans-10,cis-12-Conjugated linoleic acid reduces leptin secretion from 3T3-L1 adipocytes. , 2001, Biochemical and biophysical research communications.

[30]  B. Vessby Dietary fat and insulin action in humans , 2000, British Journal of Nutrition.

[31]  H M Roche,et al.  Effect of long-chain n-3 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism. , 2000, The American journal of clinical nutrition.

[32]  T. Matsuo,et al.  Body fat accumulation is greater in rats fed a beef tallow diet than in rats fed a safflower or soybean oil diet. , 2002, Asia Pacific journal of clinical nutrition.

[33]  K. Nakao,et al.  Downregulation of leptin by free fatty acids in rat adipocytes: effects of triacsin C, palmitate, and 2-bromopalmitate. , 2000, Metabolism: clinical and experimental.

[34]  Y. Deshaies,et al.  Regulation of leptin secretion from white adipocytes by free fatty acids. , 2003, American journal of physiology. Endocrinology and metabolism.

[35]  P. Havel Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolism. , 2004, Diabetes.

[36]  E. Kraegen,et al.  Fish oil prevents insulin resistance induced by high-fat feeding in rats. , 1987, Science.

[37]  E. Berry,et al.  Diet and disease--the Israeli paradox: possible dangers of a high omega-6 polyunsaturated fatty acid diet. , 1996, Israel journal of medical sciences.

[38]  C. Warden,et al.  Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. , 1998, Endocrinology.

[39]  F. Giorgino,et al.  Insulin signalling in human adipose tissue , 2006, Archives of physiology and biochemistry.

[40]  A. Simopoulos Is insulin resistance influenced by dietary linoleic acid and trans fatty acids? , 1994, Free radical biology & medicine.

[41]  M. C. Cha,et al.  Dietary fat type and energy restriction interactively influence plasma leptin concentration in rats. , 1998, Journal of lipid research.

[42]  G. Cooney,et al.  Mechanisms of Liver and Muscle Insulin Resistance Induced by Chronic High-Fat Feeding , 1997, Diabetes.

[43]  J. Born,et al.  Glucose metabolism rather than insulin is a main determinant of leptin secretion in humans. , 2000, The Journal of clinical endocrinology and metabolism.

[44]  T. Funahashi,et al.  Secretion of adiponectin and regulation of apM1 gene expression in human visceral adipose tissue. , 2001, Biochemical and biophysical research communications.

[45]  R. Adler,et al.  Dual regulation of leptin secretion: intracellular energy and calcium dependence of regulated pathway. , 2000, American journal of physiology. Endocrinology and metabolism.

[46]  K. Miyashita,et al.  Conjugated linoleic acid deteriorates insulin resistance in obese/diabetic mice in association with decreased production of adiponectin and leptin. , 2004, Journal of nutritional science and vitaminology.

[47]  J. Evans,et al.  Effects of metformin and vanadium on leptin secretion from cultured rat adipocytes. , 2000, Obesity research.

[48]  Armando R. Tovar,et al.  Mecanismos moleculares de acción de los ácidos grasos poliinsaturados y sus beneficios en la salud , 2005 .