论文信息 - NMR Pulse Design Using Modern Optimization Methods

NMR Pulse Design Using Modern Optimization Methods

NMR consoles give us excellent control over the intensities and phases of RF pulses, This has led to a wide variety of shaped pulses for many purposes. How- ever, perhaps this is an embarrassment of riches. If we have 512 points in a pulse shape, we must optimize over 1000 variables to find the truly "best" pulse. Recently, ro- bust, open-source solvers have become available that can deal with problems of this size. In this poster, we use these methods to design a variety of shaped pulses for a number of applications.

Christopher Kumar Anand | Alex D. Bain | A. D. Bain | Zhenghua Nie | Zhenghua Nie

[1] Burkhard Luy,et al. Optimal control design of excitation pulses that accommodate relaxation. , 2007, Journal of magnetic resonance.

[2] Burkhard Luy,et al. Reducing the duration of broadband excitation pulses using optimal control with limited RF amplitude. , 2004, Journal of magnetic resonance.

[3] Burkhard Luy,et al. Exploring the limits of broadband excitation and inversion pulses. , 2004, Journal of magnetic resonance.

[4] Lorenz T. Biegler,et al. On the implementation of an interior-point filter line-search algorithm for large-scale nonlinear programming , 2006, Math. Program..

[5] E. Zuiderweg,et al. A phase cycle scheme that significantly suppresses offset-dependent artifacts in the R2-CPMG 15N relaxation experiment. , 2004, Journal of magnetic resonance (San Diego, Calif. 1997 : Print).

[6] A. Curtis,et al. Advanced Optimization Laboratory Title : Energy-Constrained Pulse Design for MRI and NMR , 2007 .

[7] Timo O. Reiss,et al. Application of optimal control theory to the design of broadband excitation pulses for high-resolution NMR. , 2003, Journal of magnetic resonance.