Detection and susceptibility testing of Mycoplasma amphoriforme isolates from patients with respiratory tract infections.

Three isolates of Mycoplasma amphoriforme, a new Mycoplasma species rarely described to date, were obtained from respiratory tract specimens from two children and one adult with respiratory tract infections. Molecular methods were required to distinguish them from Mycoplasma pneumoniae. MICs of macrolides, tetracyclines and fluoroquinolones were identical to those for M. pneumoniae, except for that of ciprofloxacin, which was slightly more potent against M. amphoriforme. M. amphoriforme could possibly have been involved in one case of severe respiratory infection with sepsis, but further studies are needed to specify its role as a potential respiratory tract pathogen.

[1]  B. Cookson,et al.  First international spread and dissemination of the virulent Queensland community-associated methicillin-resistant Staphylococcus aureus strain. , 2010, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[2]  A. Bénard,et al.  Evaluation of Five Commercial Real-Time PCR Assays for Detection of Mycoplasma pneumoniae in Respiratory Tract Specimens , 2009, Journal of Clinical Microbiology.

[3]  P. Nordmann,et al.  Plasmid-mediated quinolone resistance in Aeromonas allosaccharophila recovered from a Swiss lake. , 2008, The Journal of antimicrobial chemotherapy.

[4]  J. Vila,et al.  Plasmid-Mediated QnrS2 Determinant from a Clinical Aeromonas veronii Isolate , 2008, Antimicrobial Agents and Chemotherapy.

[5]  P. Nordmann,et al.  Unexpected Occurrence of Plasmid-Mediated Quinolone Resistance Determinants in Environmental Aeromonas spp. , 2008, Emerging infectious diseases.

[6]  P. Nordmann,et al.  Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. , 2007, The Journal of antimicrobial chemotherapy.

[7]  K. Bhilegaonkar,et al.  Species identification of clinically important Aeromonas spp. by restriction fragment length polymorphism of 16S rDNA , 2007, Letters in applied microbiology.

[8]  Mitchell F. Balish,et al.  Ultrastructure and gliding motility of Mycoplasma amphoriforme, a possible human respiratory pathogen. , 2006, Microbiology.

[9]  D. Windsor,et al.  Mycoplasma amphoriforme sp. nov., isolated from a patient with chronic bronchopneumonia. , 2005, International journal of systematic and evolutionary microbiology.

[10]  G. Jacoby.  Mechanisms of resistance to quinolones. , 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[11]  D. Windsor,et al.  Chronic Bronchitis in Immunocompromised Patients: Association with a Novel Mycoplasma Species , 2003, European Journal of Clinical Microbiology and Infectious Diseases.

[12]  A. Martínez-Murcia,et al.  Phylogenetic analysis of members of the genus Aeromonas based on gyrB gene sequences. , 2003, International journal of systematic and evolutionary microbiology.

[13]  P. Caumette,et al.  Type II Topoisomerase Quinolone Resistance-Determining Regions of Aeromonas caviae, A. hydrophila, and A. sobria Complexes and Mutations Associated with Quinolone Resistance , 2002, Antimicrobial Agents and Chemotherapy.

[14]  A. Martínez-Murcia,et al.  Identification of Aeromonas clinical isolates by restriction fragment length polymorphism of PCR-amplified 16S rRNA genes , 1997, Journal of clinical microbiology.

[15]  H. Young.  Antimicrobial resistance spread in aquatic environments. , 1993, The Journal of antimicrobial chemotherapy.

[16]  A F Angulo,et al.  Genus- and species-specific identification of mycoplasmas by 16S rRNA amplification , 1992, Applied and environmental microbiology.