Human platelets express OATP 2 B 1 , an uptake transporter for atorvastatin
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D. Rosskopf | H. Kroemer | J. Niessen | T. Terasaki | A. Greinacher | S. Ohtsuki | S. Oswald | J. Kamiie | H. Schwertz | W. Siegmund | M. Grube | G. Jedlitschky | S. Bien | U. Strobel | H. Kawakami | Katharina Starke
[1] A. Gotto,et al. The evolving role of statins in the management of atherosclerosis. , 2000, Journal of the American College of Cardiology.
[2] A. Szuba,et al. Influence of dehydroepiandrosterone on platelet aggregation, superoxide dismutase activity and serum lipid peroxide concentrations in rabbits with induced hypercholesterolemia. , 2000, Medical science monitor : international medical journal of experimental and clinical research.
[3] Tetsuya Terasaki,et al. Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria , 2008, Pharmaceutical Research.
[4] M. Fromm,et al. Pharmacogenomics of human OATP transporters , 2006, Naunyn-Schmiedeberg's Archives of Pharmacology.
[5] N. Lameire,et al. Pharmacokinetics of atorvastatin and its metabolites after single and multiple dosing in hypercholesterolaemic haemodialysis patients. , 2003, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[6] M. Becchi,et al. Occurrence and biological effects of cholesteryl sulfate on blood platelets. , 1995, Biochimica et biophysica acta.
[7] J. Aznar,et al. Effect of atorvastatin upon platelet activation in hypercholesterolemia, evaluated by flow cytometry. , 2005, Thrombosis research.
[8] U. Cogan,et al. Lovastatin decreases plasma and platelet cholesterol levels and normalizes elevated platelet fluidity and aggregation in hypercholesterolemic patients. , 1994, Metabolism: clinical and experimental.
[9] C. Iden,et al. Homocysteine Induces 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Vascular Endothelial Cells: A Mechanism for Development of Atherosclerosis? , 2002, Circulation.
[10] P. K. Smith,et al. Measurement of protein using bicinchoninic acid. , 1985, Analytical biochemistry.
[11] H. Kroemer,et al. The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage. , 2004, Blood.
[12] D. Keppler,et al. A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. , 2000, American journal of physiology. Gastrointestinal and liver physiology.
[13] R. Tsien,et al. A new generation of Ca2+ indicators with greatly improved fluorescence properties. , 1985, The Journal of biological chemistry.
[14] Markus Grube,et al. EXPRESSION, LOCALIZATION, AND FUNCTION OF THE CARNITINE TRANSPORTER OCTN2 (SLC22A5) IN HUMAN PLACENTA , 2005, Drug Metabolism and Disposition.
[15] P. Meier,et al. Functional Analysis of the Extracellular Cysteine Residues in the Human Organic Anion Transporting Polypeptide, OATP2B1 , 2006, Molecular Pharmacology.
[16] D. Rosskopf,et al. Signal transduction of somatostatin in human B lymphoblasts. , 2003, American journal of physiology. Cell physiology.
[17] A. Sedman,et al. Multiple‐dose pharmacokinetics, pharmacodynamics, and safety of atorvastatin, an inhibitor of HMG‐CoA reductase, in healthy subjects , 1996, Clinical pharmacology and therapeutics.
[18] R. Kim,et al. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. , 2006, Gastroenterology.
[19] J. Farmer. High-dose atorvastatin after stroke or transient ischemic attack. , 2007, Current atherosclerosis reports.
[20] M. Endres,et al. Effects of Statins on Endothelium and Signaling Mechanisms , 2004, Stroke.
[21] B. Kinsella,et al. Effect of the statin atorvastatin on intracellular signalling by the prostacyclin receptor in vitro and in vivo , 2004, British journal of pharmacology.
[22] Thomas Rau,et al. Atorvastatin desensitizes beta-adrenergic signaling in cardiac myocytes via reduced isoprenylation of G-protein gamma-subunits. , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[23] L. Lemberg,et al. Statin pleiotropy: fact or fiction? , 2004, American journal of critical care : an official publication, American Association of Critical-Care Nurses.
[24] 曲东锋. Stroke Prevention by Aggressive Reduction in Cholesterol Levels , 2004 .
[25] J. Mehta,et al. Anti-thrombotic Effects of Atorvastatin-An Effect Unrelated to Lipid Lowering , 2002, Journal of cardiovascular pharmacology and therapeutics.
[26] J. Nezu,et al. Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. , 2000, Biochemical and biophysical research communications.
[27] D. Dixon,et al. Activated platelets mediate inflammatory signaling by regulated interleukin 1β synthesis , 2001, The Journal of cell biology.
[28] K. Swoboda,et al. Escaping the Nuclear Confines: Signal-Dependent Pre-mRNA Splicing in Anucleate Platelets , 2005, Cell.
[29] H. Kroemer,et al. Subfractionation and purification of intracellular granule-structures of human platelets: an improved method based on magnetic sorting. , 2007, Journal of immunological methods.
[30] G. Davı̀,et al. Inhibition of thromboxane biosynthesis and platelet function by simvastatin in type IIa hypercholesterolemia. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[31] W. Vainchenker,et al. Biosynthesis of major platelet proteins in human blood platelets. , 1987, European journal of biochemistry.
[32] W. Southern. Intensive lipid lowering with atorvastatin in coronary disease. , 2005, The New England journal of medicine.
[33] Nigel Mackman,et al. Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human platelets , 2006, The Journal of experimental medicine.
[34] J. Pincus. Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) , 1998, The American journal of cardiology.