Diffusion resistance and enzyme activity decay in a pellet

The effective enzyme activity decay can be decreased by diffusion limitation in the immobilized pellet. Thiele modulus changes and/or poisoning of various enzyme forms are two phenomena which are influenced by diffusion limitation. This article considers these effects on enzyme decay as applied to glucose isomerase.

[1]  D. Ollis Diffusion influences in denaturable insolubilized enzyme catalysis , 1972, Biotechnology and bioengineering.

[2]  Åke Björck,et al.  Numerical Methods , 2021, Markov Renewal and Piecewise Deterministic Processes.

[3]  R. Korus,et al.  The influence of diffusion on the apparent rate of denaturation of gel entrapped enzymes , 1975 .