Functionalized MoS(2) nanosheet-based field-effect biosensor for label-free sensitive detection of cancer marker proteins in solution.

Label-free MoS(2) nanosheet-based field-effect biosensor detects cancer marker protein Prostate Specific Antigen in real time with high sensitivity and selectivity, exhibiting great potential in point-of-care diagnostics application.

[1]  Y. Chang,et al.  Carbon nanotube DNA sensor and sensing mechanism. , 2006, Nano letters.

[2]  Filip Braet,et al.  Carbon nanomaterials in biosensors: should you use nanotubes or graphene? , 2010, Angewandte Chemie.

[3]  Chan Woo Park,et al.  Ultrasensitive, label-free, and real-time immunodetection using silicon field-effect transistors , 2007 .

[4]  J. Appenzeller,et al.  High performance multilayer MoS2 transistors with scandium contacts. , 2013, Nano letters.

[5]  Bin Liu,et al.  Hysteresis in single-layer MoS2 field effect transistors. , 2012, ACS nano.

[6]  Charles M. Lieber,et al.  Subthreshold regime has the optimal sensitivity for nanowire FET biosensors. , 2010, Nano letters.

[7]  P M Campbell,et al.  Chemical vapor sensing with monolayer MoS2. , 2013, Nano letters.

[8]  E. Plueddemann,et al.  SILANE COUPLING AGENTS , 1982 .

[9]  A. Radenović,et al.  Single-layer MoS2 transistors. , 2011, Nature nanotechnology.

[10]  Ajay Agarwal,et al.  Label-free electrical detection of cardiac biomarker with complementary metal-oxide semiconductor-compatible silicon nanowire sensor arrays. , 2009, Analytical chemistry.

[11]  Hugen Yan,et al.  Anomalous lattice vibrations of single- and few-layer MoS2. , 2010, ACS nano.

[12]  C. Mathers,et al.  Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 , 2010, International journal of cancer.

[13]  Yuyuan Tian,et al.  Dielectric screening enhanced performance in graphene FET. , 2009, Nano letters.

[14]  R. Ruoff,et al.  Graphene and Graphene Oxide: Synthesis, Properties, and Applications , 2010, Advanced materials.

[15]  Ruth Etzioni,et al.  Early detection: The case for early detection , 2003, Nature Reviews Cancer.

[16]  Kyu-Sik Shin,et al.  Quantitative measurements of C-reactive protein using silicon nanowire arrays , 2008, International journal of nanomedicine.

[17]  R. Frindt,et al.  Single Crystals of MoS2 Several Molecular Layers Thick , 1966 .

[18]  J. Shan,et al.  Atomically thin MoS₂: a new direct-gap semiconductor. , 2010, Physical review letters.

[19]  Gengfeng Zheng,et al.  Nanowire sensors for medicine and the life sciences. , 2006, Nanomedicine.

[20]  N. Mohanty,et al.  Graphene-based single-bacterium resolution biodevice and DNA transistor: interfacing graphene derivatives with nanoscale and microscale biocomponents. , 2008, Nano letters.

[21]  Fred J Sigworth,et al.  Importance of the Debye screening length on nanowire field effect transistor sensors. , 2007, Nano letters.

[22]  Chao Li,et al.  Complementary detection of prostate-specific antigen using In2O3 nanowires and carbon nanotubes. , 2005, Journal of the American Chemical Society.

[23]  Hua Zhang,et al.  Single-layer MoS2 phototransistors. , 2012, ACS nano.

[24]  G. S. Wilson,et al.  Electrochemical biosensors: recommended definitions and classification. , 2001, Biosensors & bioelectronics.

[25]  Mark A. Reed,et al.  Label-free immunodetection with CMOS-compatible semiconducting nanowires , 2007, Nature.

[26]  P. Humphrey,et al.  The early detection of prostate carcinoma with prostate specific antigen , 1997, Cancer.

[27]  Hua Zhang,et al.  Fabrication of single- and multilayer MoS2 film-based field-effect transistors for sensing NO at room temperature. , 2012, Small.

[28]  J. Kong,et al.  Integrated circuits based on bilayer MoS₂ transistors. , 2012, Nano letters.

[29]  Gengfeng Zheng,et al.  Fabrication of silicon nanowire devices for ultrasensitive, label-free, real-time detection of biological and chemical species , 2006, Nature Protocols.

[30]  Li Zhang,et al.  Silicon nanowire biosensor for highly sensitive and rapid detection of Dengue virus , 2010 .

[31]  Dar-Bin Shieh,et al.  Control and Detection of Organosilane Polarization on Nanowire Field-Effect Transistors , 2007 .

[32]  Bastian E. Rapp,et al.  Biosensors with label-free detection designed for diagnostic applications , 2010, Analytical and bioanalytical chemistry.

[33]  Jia Zhang,et al.  Carbon Nanostructure-Based Field-Effect Transistors for Label-Free Chemical/Biological Sensors , 2010, Sensors.

[34]  Dominique Baillargeat,et al.  From Bulk to Monolayer MoS2: Evolution of Raman Scattering , 2012 .

[35]  Gengfeng Zheng,et al.  Multiplexed electrical detection of cancer markers with nanowire sensor arrays , 2005, Nature Biotechnology.

[36]  Qiyuan He,et al.  Fabrication of flexible MoS2 thin-film transistor arrays for practical gas-sensing applications. , 2012, Small.

[37]  Andre K. Geim,et al.  The rise of graphene. , 2007, Nature materials.

[38]  Peng Chen,et al.  Biological and chemical sensors based on graphene materials. , 2012, Chemical Society reviews.

[39]  Andre K. Geim,et al.  Two-dimensional atomic crystals. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[40]  A M Ward,et al.  Prostate specific antigen: biology, biochemistry and available commercial assays , 2001, Annals of clinical biochemistry.

[41]  Andre K. Geim,et al.  Electric Field Effect in Atomically Thin Carbon Films , 2004, Science.

[42]  S. Schreiber,et al.  Printing proteins as microarrays for high-throughput function determination. , 2000, Science.