Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis.
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J. Dagvadorj | Shuang Chen | E. Erbay | E. Tarling | T. Crother | M. Arditi | K. Shimada | G. Tumurkhuu | Rebecca A. Porritt
[1] P. Shah,et al. Chlamydia and Lipids Engage a Common Signaling Pathway That Promotes Atherogenesis. , 2018, Journal of the American College of Cardiology.
[2] S. Hiller,et al. The Gasdermin‐D pore acts as a conduit for IL‐1β secretion in mice , 2018, European journal of immunology.
[3] P. Libby,et al. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease , 2017, The New England journal of medicine.
[4] J. Kearney,et al. The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome , 2017, The Journal of Biological Chemistry.
[5] Minal Mulye,et al. Manipulation of Host Cholesterol by Obligate Intracellular Bacteria , 2017, Front. Cell. Infect. Microbiol..
[6] R. Gottlieb,et al. Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis. , 2016, Circulation research.
[7] V. Nizet,et al. IL-1β is an innate immune sensor of microbial proteolysis , 2016, Science Immunology.
[8] P. Eriksson,et al. NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis , 2016, Journal of the American Heart Association.
[9] P. Ridker,et al. Circulating N-Linked Glycoprotein Acetyls and Longitudinal Mortality Risk. , 2016, Circulation research.
[10] K. Bornfeldt,et al. Macrophage Phenotype and Function in Different Stages of Atherosclerosis. , 2016, Circulation research.
[11] M. Cuchel,et al. ABCA1 and Inflammation: From Animal Models to Humans. , 2015, Arteriosclerosis, thrombosis, and vascular biology.
[12] E. Latz,et al. The inflammasomes and autoinflammatory syndromes. , 2015, Annual review of pathology.
[13] Xi-Long Zheng,et al. Chlamydia pneumoniae negatively regulates ABCA1 expression via TLR2-Nuclear factor-kappa B and miR-33 pathways in THP-1 macrophage-derived foam cells. , 2014, Atherosclerosis.
[14] Sarah Parish,et al. Effects of extended-release niacin with laropiprant in high-risk patients. , 2014, The New England journal of medicine.
[15] N. Sinha,et al. Pathogenicity of Mycobacterium tuberculosis Is Expressed by Regulating Metabolic Thresholds of the Host Macrophage , 2014, PLoS pathogens.
[16] E. Verdin,et al. Ketone bodies as signaling metabolites , 2014, Trends in Endocrinology & Metabolism.
[17] Huidong Shi,et al. Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. , 2014, Immunity.
[18] Christine E. Becker,et al. CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation , 2013, Nature Immunology.
[19] A. Jefferson,et al. Nicotinic Acid Receptor GPR109A Is Down-Regulated in Human Macrophage-Derived Foam Cells , 2013, Heart.
[20] A. Jefferson,et al. 167 NICOTINIC ACID RECEPTOR GPR109A IS DOWN-REGULATED IN HUMAN MACROPHAGE-DERIVED FOAM CELLS , 2013, Heart.
[21] M. Landray,et al. HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment , 2013, European heart journal.
[22] P. Verma,et al. Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype. , 2012, Cell host & microbe.
[23] T. Crother,et al. Innate immune responses to Chlamydia pneumoniae infection: role of TLRs, NLRs, and the inflammasome. , 2012, Microbes and infection.
[24] R. Judd,et al. Effects of high fat diet on GPR109A and GPR81 gene expression. , 2012, Biochemical and biophysical research communications.
[25] J. Gage,et al. Caspase-1 deficiency decreases atherosclerosis in apolipoprotein E-null mice. , 2012, The Canadian journal of cardiology.
[26] D. Greaves,et al. Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms , 2012, Arteriosclerosis, thrombosis, and vascular biology.
[27] B. Chaitman,et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. , 2011, The New England journal of medicine.
[28] P. Edwards,et al. ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter , 2011, Proceedings of the National Academy of Sciences.
[29] M. Rosenfeld,et al. Pathogens and atherosclerosis: Update on the potential contribution of multiple infectious organisms to the pathogenesis of atherosclerosis , 2011, Thrombosis and Haemostasis.
[30] E. Latz,et al. NLRP3 inflammasomes link inflammation and metabolic disease. , 2011, Trends in immunology.
[31] Moshe Arditi,et al. Caspase-1 Dependent IL-1β Secretion Is Critical for Host Defense in a Mouse Model of Chlamydia pneumoniae Lung Infection , 2011, PloS one.
[32] K. Moore,et al. Macrophages in the Pathogenesis of Atherosclerosis , 2011, Cell.
[33] J. Tschopp,et al. Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome , 2011, Cell Death and Disease.
[34] S. Offermanns,et al. Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. , 2011, The Journal of clinical investigation.
[35] Shuang Chen,et al. IL-17A Is Proatherogenic in High-Fat Diet-Induced and Chlamydia pneumoniae Infection-Accelerated Atherosclerosis in Mice , 2010, The Journal of Immunology.
[36] E. Lien,et al. Inflammation and Fibrosis during Chlamydia pneumoniae Infection Is Regulated by IL-1 and the NLRP3/ASC Inflammasome , 2010, The Journal of Immunology.
[37] M. Elkind. Infectious burden: a new risk factor and treatment target for atherosclerosis. , 2010, Infectious disorders drug targets.
[38] G. Cook,et al. The NLRP3 inflammasome, a target for therapy in diverse disease states , 2010, European journal of immunology.
[39] K. Moore,et al. NLRP3 inflamasomes are required for atherogenesis and activated by cholesterol crystals that form early in disease , 2010, Nature.
[40] Shuiping Zhao,et al. Niacin Promotes Cholesterol Efflux through Stimulation of the PPARγ-LXRα-ABCA1 Pathway in 3T3-L1 Adipocytes , 2009, Pharmacology.
[41] P. Eriksson,et al. A functional interleukin-1 receptor antagonist polymorphism influences atherosclerosis development. The interleukin-1beta:interleukin-1 receptor antagonist balance in atherosclerosis. , 2009, Circulation journal : official journal of the Japanese Circulation Society.
[42] C. Eder. Mechanisms of interleukin-1beta release. , 2009, Immunobiology.
[43] Shuang Chen,et al. Chlamydia pneumoniae-Induced Foam Cell Formation Requires MyD88-Dependent and -Independent Signaling and Is Reciprocally Modulated by Liver X Receptor Activation1 , 2008, The Journal of Immunology.
[44] P. Shah,et al. TLR/MyD88 and Liver X Receptor α Signaling Pathways Reciprocally Control Chlamydia pneumoniae-Induced Acceleration of Atherosclerosis1 , 2008, The Journal of Immunology.
[45] A. Tall,et al. Increased Inflammatory Gene Expression in ABC Transporter–Deficient Macrophages: Free Cholesterol Accumulation, Increased Signaling via Toll-Like Receptors, and Neutrophil Infiltration of Atherosclerotic Lesions , 2008, Circulation.
[46] M. Willingham,et al. Increased Cellular Free Cholesterol in Macrophage-specific Abca1 Knock-out Mice Enhances Pro-inflammatory Response of Macrophages* , 2008, Journal of Biological Chemistry.
[47] J. Guyton. Niacin in cardiovascular prevention: mechanisms, efficacy, and safety , 2007, Current opinion in lipidology.
[48] Nanping Wang,et al. ROS and NF-κB but not LXR mediate IL-1β signaling for the downregulation of ATP-binding cassette transporter A1 , 2007 .
[49] J. Heinecke,et al. ATP-binding cassette transporter A1: a cell cholesterol exporter that protects against cardiovascular disease. , 2005, Physiological reviews.
[50] D. Connolly,et al. (d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G* , 2005, Journal of Biological Chemistry.
[51] P. Parnet,et al. ATP binding cassette transporter ABC1 is required for the release of interleukin‐1β by P2X7‐stimulated and lipopolysaccharide‐primed mouse Schwann cells , 2005, Glia.
[52] S. Akira,et al. Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[53] G. Cheng,et al. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. , 2003, Molecular cell.
[54] S. Tunaru,et al. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect , 2003, Nature Medicine.
[55] P. Libby. Inflammation in atherosclerosis , 2002, Nature.
[56] A. von Eckardstein,et al. The ATP binding cassette transporter A1 contributes to the secretion of interleukin 1beta from macrophages but not from monocytes. , 2002, Biochemical and biophysical research communications.
[57] M. Fishbein,et al. Toll-Like Receptor-4 Is Expressed by Macrophages in Murine and Human Lipid-Rich Atherosclerotic Plaques and Upregulated by Oxidized LDL , 2001, Circulation.
[58] H. Brewer,et al. Regulation and intracellular trafficking of the ABCA1 transporter. , 2001, Journal of lipid research.
[59] H. Brewer,et al. Cellular Localization and Trafficking of the Human ABCA1 Transporter* 210 , 2001, The Journal of Biological Chemistry.
[60] J. Arnal,et al. Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice. , 1998, Circulation.
[61] A Rubartelli,et al. Interleukin-1beta secretion is impaired by inhibitors of the Atp binding cassette transporter, ABC1. , 1997, Blood.
[62] B. Verrier,et al. ABC1, an ATP Binding Cassette Transporter Required for Phagocytosis of Apoptotic Cells, Generates a Regulated Anion Flux after Expression in Xenopus laevis Oocytes* , 1997, The Journal of Biological Chemistry.
[63] J. Stamler,et al. Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. , 1986, Journal of the American College of Cardiology.
[64] M. He,et al. OxLDL-induced IL-1beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation , 2013, Inflammation Research.
[65] L. Campbell,et al. Chlamydia pneumoniae — an infectious risk factor for atherosclerosis? , 2004, Nature Reviews Microbiology.