Spatial and temporal variability of the complex fractionated atrial electrogram activity and dominant frequency in human atrial fibrillation

The presence of complex fractionated atrial electrograms (CFAEs) and high dominant frequencies (DFs) during atrial fibrillation (AF) have been demonstrated to be related to AF maintenance. Therefore, sequential mapping of CFAEs and DFs have been used for target sites of AF ablation. However, such mapping strategies are valid only if the CFAEs and DFs are spatiotemporally stable during the mapping procedure. We obtained spatially stable multi‐electrode recordings to assess the spatiotemporal stability of CFAEs and DFs.

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