Management and Manufacturing Process of Biologics

[1]  J. Collins,et al.  A brief history of synthetic biology , 2014, Nature Reviews Microbiology.

[2]  S. Ramakrishna,et al.  Cultured meat: state of the art and future , 2018 .

[3]  Rachel Chen,et al.  Biotechnological applications of bacterial protein secretion: from therapeutics to biofuel production. , 2013, Research in microbiology.

[4]  F. Baneyx.  Recombinant protein expression in Escherichia coli. , 1999, Current opinion in biotechnology.

[5]  Jian Chen,et al.  Molecular engineering of secretory machinery components for high-level secretion of proteins in Bacillus species , 2014, Journal of Industrial Microbiology & Biotechnology.

[6]  H. Daniell,et al.  Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptide. , 2011, Plant biotechnology journal.

[7]  Lidia Westers,et al.  Bacillus subtilis as cell factory for pharmaceutical proteins: a biotechnological approach to optimize the host organism. , 2004, Biochimica et biophysica acta.

[8]  W. Schumann,et al.  Optimization of the secretion pathway for heterologous proteins in Bacillus subtilis , 2015, Biotechnology and Bioprocess Engineering.

[9]  Jie Yu,et al.  A plant-based cholera toxin B subunit–insulin fusion protein protects against the development of autoimmune diabetes , 1998, Nature Biotechnology.

[10]  Jens Nielsen,et al.  Production of biopharmaceutical proteins by yeast , 2012, Bioengineered.

[11]  Zhan-Qiu Yang,et al.  Culture Conditions and Types of Growth Media for Mammalian Cells , 2012 .

[12]  Florian M Wurm,et al.  First CHO genome , 2011, Nature Biotechnology.

[13]  Timothy J Griffin,et al.  Advancing mammalian cell culture engineering using genome-scale technologies. , 2007, Trends in biotechnology.

[14]  G. Lee,et al.  Protein reference mapping of dihydrofolate reductase‐deficient CHO DG44 cell lines using 2‐dimensional electrophoresis , 2010, Proteomics.

[15]  H. Matsui,et al.  Hyper-production of an isomalto-dextranase of an Arthrobacter sp. by a proteases-deficient Bacillus subtilis: sequencing, properties, and crystallization of the recombinant enzyme , 2004, Applied Microbiology and Biotechnology.

[16]  Gabriel Waksman,et al.  Secretion systems in Gram-negative bacteria: structural and mechanistic insights , 2015, Nature Reviews Microbiology.

[17]  J. Hartley.  Why proteins in mammalian cells? , 2012, Methods in molecular biology.

[18]  T. Takeuchi,et al.  Processing of mutated proinsulin with tetrabasic cleavage sites to bioactive insulin in the non‐endocrine cell line, COS‐7 , 1992, FEBS letters.

[19]  Sibel Ÿztürk,et al.  Fed-Batch Biomolecule Production by Bacillus subtilis: A State of the Art Review. , 2016, Trends in biotechnology.

[20]  R. Owens,et al.  Recent advances in the production of proteins in insect and mammalian cells for structural biology. , 2010, Journal of structural biology.

[21]  J. V. Van Impe,et al.  Recombinant protein production and streptomycetes. , 2012, Journal of biotechnology.

[22]  Cheng Li,et al.  Type III secretion as a generalizable strategy for the production of full‐length biopolymer‐forming proteins , 2016, Biotechnology and bioengineering.

[23]  C. Nykiforuk,et al.  Transgenic expression and recovery of biologically active recombinant human insulin from Arabidopsis thaliana seeds. , 2006, Plant biotechnology journal.

[24]  A. Driessen,et al.  Sec- and Tat-mediated protein secretion across the bacterial cytoplasmic membrane--distinct translocases and mechanisms. , 2008, Biochimica et biophysica acta.

[25]  D. Mark,et al.  Site-specific mutagenesis of the human interleukin-2 gene: structure-function analysis of the cysteine residues. , 1984, Science.

[26]  J. Nielsen,et al.  Biopharmaceutical protein production by Saccharomyces cerevisiae: current state and future prospects , 2014 .

[27]  Chi-Long Chen,et al.  Long-term growth comparison studies of FBS and FBS alternatives in six head and neck cell lines , 2017, PloS one.

[28]  Marcos Antonio de Oliveira,et al.  Biopharmaceuticals from microorganisms: from production to purification , 2016, Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology].

[29]  Germán L. Rosano,et al.  Recombinant protein expression in Escherichia coli: advances and challenges , 2014, Front. Microbiol..