Transcript signature predicts tissue NK cell content and defines renal cell carcinoma subgroups independent of TNM staging

[1]  M. Koch,et al.  Natural Killer Cells are Scarce in Colorectal Carcinoma Tissue Despite High Levels of Chemokines and Cytokines , 2011, Clinical Cancer Research.

[2]  J. Larkin,et al.  Challenges and opportunities for converting renal cell carcinoma into a chronic disease with targeted therapies , 2011, British Journal of Cancer.

[3]  F. Shi,et al.  Central nervous system (CNS)–resident natural killer cells suppress Th17 responses and CNS autoimmune pathology , 2010, The Journal of experimental medicine.

[4]  Holger Moch,et al.  Reassessing the current UICC/AJCC TNM staging for renal cell carcinoma. , 2009, European urology.

[5]  Yi Han,et al.  Overview of Artificial Neural Networks , 2009, Artificial Neural Networks.

[6]  Jeremy MG Taylor,et al.  Validation of Biomarker-Based Risk Prediction Models , 2008, Clinical Cancer Research.

[7]  M. Wong The current role of immunotherapy for renal cell carcinoma in the era of targeted therapeutics , 2008, Current oncology reports.

[8]  E. Noessner,et al.  Immune suppression in renal cell carcinoma. , 2007, Seminars in cancer biology.

[9]  É. Vivier,et al.  Natural killer cells: from CD3(-)NKp46(+) to post-genomics meta-analyses. , 2007, Current opinion in immunology.

[10]  G. Martignoni,et al.  TNM staging system for renal-cell carcinoma: current status and future perspectives. , 2007, The Lancet. Oncology.

[11]  Daniel Olive,et al.  Deficient expression of NCR in NK cells from acute myeloid leukemia: Evolution during leukemia treatment and impact of leukemia cells in NCRdull phenotype induction. , 2007, Blood.

[12]  P. Nelson,et al.  Cytotoxic Markers and Frequency Predict Functional Capacity of Natural Killer Cells Infiltrating Renal Cell Carcinoma , 2006, Clinical Cancer Research.

[13]  G. Girolomoni,et al.  CD56brightCD16– NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation , 2006, European journal of immunology.

[14]  L. Kaer,et al.  NK cells promote islet allograft tolerance via a perforin-dependent mechanism , 2005, Nature Network Boston.

[15]  J. A. van der Laak,et al.  Intratumoral Recombinant Human Interleukin-12 Administration in Head and Neck Squamous Cell Carcinoma Patients Modifies Locoregional Lymph Node Architecture and Induces Natural Killer Cell Infiltration in the Primary Tumor , 2005, Clinical Cancer Research.

[16]  P. Allavena,et al.  Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors. , 2004, Seminars in cancer biology.

[17]  C. Cohen,et al.  Gene expression analysis in renal biopsies. , 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[18]  K. Ley,et al.  Trafficking of natural killer cells. , 2004, Current molecular medicine.

[19]  P. Kuppen,et al.  NK cells and the tumour microenvironment: implications for NK-cell function and anti-tumour activity. , 2003, Trends in immunology.

[20]  Taoyong Chen,et al.  Chemoattraction, adhesion and activation of natural killer cells are involved in the antitumor immune response induced by fractalkine/CX3CL1. , 2003, Immunology letters.

[21]  J. Hanna,et al.  CXCL12 expression by invasive trophoblasts induces the specific migration of CD16- human natural killer cells. , 2003, Blood.

[22]  S. Mocellin,et al.  Use of quantitative real-time PCR to determine immune cell density and cytokine gene profile in the tumor microenvironment. , 2003, Journal of immunological methods.

[23]  L. Moretta,et al.  The impaired NK cell cytolytic function in viremic HIV‐1 infection is associated with a reduced surface expression of natural cytotoxicity receptors (NKp46, NKp30 and NKp44) , 2003, European journal of immunology.

[24]  N. Cascinelli,et al.  Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma. , 2003, Cancer research.

[25]  A. Moffett-King Natural killer cells and pregnancy , 2002, Nature Reviews Immunology.

[26]  Kazuyoshi Takeda,et al.  New aspects of natural-killer-cell surveillance and therapy of cancer , 2002, Nature Reviews Cancer.

[27]  F. Shi,et al.  The Natural Killer Cell – Friend or Foe in Autoimmune Disease? , 2002, Scandinavian journal of immunology.

[28]  M. Caligiuri,et al.  The biology of human natural killer-cell subsets. , 2001, Trends in immunology.

[29]  T. Imai,et al.  Fractalkine and vascular injury. , 2001, Trends in immunology.

[30]  J. Lieberman,et al.  Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection. , 2001, Blood.

[31]  K. Nakachi,et al.  Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population , 2000, The Lancet.

[32]  D. Speiser,et al.  Cutting Edge: Cytolytic Effector Function in Human Circulating CD8+ T Cells Closely Correlates with CD56 Surface Expression1 , 2000, The Journal of Immunology.

[33]  D. Patel,et al.  Fractalkine and CX3CR1 Mediate a Novel Mechanism of Leukocyte Capture, Firm Adhesion, and Activation under Physiologic Flow , 1998, The Journal of experimental medicine.

[34]  P. Hersey,et al.  Relationship between natural killer cell activity and histological features of lymphocyte infiltration and partial regression of the primary tumor in melanoma patients. , 1982, Cancer research.

[35]  G. Trinchieri,et al.  Human natural killer cells. , 1979, Transplantation proceedings.