History and introduction of dendrimers

Abstract A dendrimer is one of the nanotechnology-based novel drug delivery systems that has attracted the attention of numerous researchers in the field of drug delivery. These three-dimensional nano-engineered polymeric structures provide uniform size and options for surface functionalization to develop an attractive tool for biomedical application. Hydrophobic as well as hydrophilic components including genetic and imaging materials could be delivered using this platform. The application of this delivery system has now been extended against several diseases in order to circumvent the limitations of conventional deliveries. Thus, this chapter is focused to provide the history of dendrimer development with different types, synthesis, properties, and application of dendrimer in the biomedical field.