Recent advances in strategies to target the behavior of macrophages in wound healing.

[1]  L. Tao,et al.  Extended characterization of IL-33/ST2 as a predictor for wound age determination in skin wound tissue samples of humans and mice , 2023, International Journal of Legal Medicine.

[2]  Youhua Xu,et al.  High glucose-induced STING activation inhibits diabetic wound healing through promoting M1 polarization of macrophages , 2023, Cell death discovery.

[3]  J. Yang,et al.  SENP3 deletion promotes M2 macrophage polarization and accelerates wound healing through smad6/IκB/p65 signaling pathway , 2023, Heliyon.

[4]  B. Ghosh,et al.  Pharmacological blockade of HDAC3 accelerates diabetic wound healing by regulating macrophage activation. , 2023, Life sciences.

[5]  J. Mattner,et al.  CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation , 2023, Frontiers in Immunology.

[6]  S. Seité,et al.  The impact of visible scars on well‐being and quality of life: An international epidemiological survey in adults , 2023, Journal of the European Academy of Dermatology and Venereology : JEADV.

[7]  S. Kuo,et al.  Cost-effectiveness of Novel Macrophage-Regulating Treatment for Wound Healing in Patients With Diabetic Foot Ulcers From the Taiwan Health Care Sector Perspective , 2023, JAMA network open.

[8]  Yu Ji,et al.  CCL6 promotes M2 polarization and inhibits macrophage autophagy by activating PI3‐kinase/Akt signalling pathway during skin wound healing , 2022, Experimental dermatology.

[9]  R. Abdulah,et al.  Recent Update on the Anti-Inflammatory Activities of Propolis , 2022, Molecules.

[10]  Weifeng He,et al.  P311 promotes IL-4R-mediated M2 polarization of macrophages to enhance angiogenesis for efficient skin wound healing. , 2022, The Journal of investigative dermatology.

[11]  Jui-Ching Chen,et al.  New Horizons of Macrophage Immunomodulation in the Healing of Diabetic Foot Ulcers , 2022, Pharmaceutics.

[12]  Lijun Sun,et al.  BCR-Associated Protein 31 Regulates Macrophages Polarization and Wound Healing Function via Early Growth Response 2/C/EBPβ and IL-4Rα/C/EBPβ Pathways , 2022, The Journal of Immunology.

[13]  Satoru Takahashi,et al.  Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing , 2022, International journal of molecular sciences.

[14]  Maxim N. Artyomov,et al.  The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging. , 2022, Immunity.

[15]  J. Guthridge,et al.  The promise of precision medicine in rheumatology , 2022, Nature Medicine.

[16]  U. Dianzani,et al.  ICOSL Stimulation by ICOS-Fc Accelerates Cutaneous Wound Healing In Vivo , 2022, International journal of molecular sciences.

[17]  A. Cowin,et al.  Flightless I Negatively Regulates Macrophage Surface TLR4, Delays Early Inflammation, and Impedes Wound Healing , 2022, Cells.

[18]  L. Ivashkiv,et al.  CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes , 2022, Nature Communications.

[19]  Chih-Chiang Chen,et al.  Restoring Prohealing/Remodeling-Associated M2a/c Macrophages Using ON101 Accelerates Diabetic Wound Healing , 2022, JID innovations : skin science from molecules to population health.

[20]  K. Ravichandran,et al.  Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes , 2022, Nature.

[21]  K. Kishi,et al.  Single-Cell RNA-seq Analysis Reveals Cellular Functional Heterogeneity in Dermis Between Fibrotic and Regenerative Wound Healing Fates , 2022, Frontiers in Immunology.

[22]  T. Koh,et al.  Monocyte/Macrophage Heterogeneity during Skin Wound Healing in Mice , 2022, The Journal of Immunology.

[23]  P. Loke,et al.  Redefining inflammatory macrophage phenotypes across stages and tissues by single-cell transcriptomics , 2022, Science Immunology.

[24]  D. Çakan.  The Effect of MMP-1 on Wound Healing and Scar Formation , 2022, Aesthetic Plastic Surgery.

[25]  Lihong Wang,et al.  The Role of microRNA in the Inflammatory Response of Wound Healing , 2022, Frontiers in Immunology.

[26]  Xiaofeng Ding,et al.  IL-25 improves diabetic wound healing through stimulating M2 macrophage polarization and fibroblast activation. , 2022, International immunopharmacology.

[27]  N. Tan,et al.  Single-cell analysis of skin immune cells reveals an Angptl4-ifi20b axis that regulates monocyte differentiation during wound healing , 2022, Cell Death & Disease.

[28]  A. Burlui,et al.  Targeting Systemic Sclerosis from Pathogenic Mechanisms to Clinical Manifestations: Why IL-6? , 2022, Biomedicines.

[29]  M. Brans,et al.  CXCL4 drives fibrosis by promoting several key cellular and molecular processes. , 2022, Cell reports.

[30]  L. Ng,et al.  Skin‐ny deeping: Uncovering immune cell behavior and function through imaging techniques * , 2021, Immunological reviews.

[31]  Scott N. Mueller,et al.  Moving beyond velocity: Opportunities and challenges to quantify immune cell behavior * , 2021, Immunological reviews.

[32]  Bo Zhang,et al.  FOXM1 accelerates wound healing in diabetic foot ulcer by inducing M2 macrophage polarization through a mechanism involving SEMA3C/NRP2/Hedgehog signaling. , 2021, Diabetes research and clinical practice.

[33]  D. Hume,et al.  Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair. , 2021, Seminars in Immunology.

[34]  J. Uitto,et al.  Lack of efficacy of dupilumab in the treatment of keloid disorder , 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

[35]  G. Ning,et al.  Effect of a Novel Macrophage-Regulating Drug on Wound Healing in Patients With Diabetic Foot Ulcers , 2021, JAMA network open.

[36]  R. Lafyatis,et al.  Therapeutic Approaches to Systemic Sclerosis: Recent Approvals and Future Candidate Therapies , 2021, Clinical Reviews in Allergy & Immunology.

[37]  Colin G. White-Dzuro,et al.  Successful Prevention of Secondary Burn Progression Using Infliximab Hydrogel: A Murine Model , 2021, Burns.

[38]  A. Shafiee,et al.  Wound Healing: From Passive to Smart Dressings , 2021, Advanced healthcare materials.

[39]  R. A. Franklin.  Fibroblasts and macrophages: Collaborators in tissue homeostasis , 2021, Immunological reviews.

[40]  K. Liechty,et al.  Macrophage Polarization and Diabetic Wound Healing. , 2021, Translational research : the journal of laboratory and clinical medicine.

[41]  M. Ruzek,et al.  Adalimumab Induces a Wound Healing Profile in Patients with Hidradenitis Suppurativa by Regulating Macrophage Differentiation and Matrix Metalloproteinase Expression. , 2021, The Journal of investigative dermatology.

[42]  Mikaël M. Martino,et al.  Restoration of the healing microenvironment in diabetic wounds with matrix-binding IL-1 receptor antagonist , 2021, Communications biology.

[43]  W. Sequeira,et al.  Ulcerative cutaneous sarcoidosis successfully treated with infliximab , 2021, Clinical Rheumatology.

[44]  Yu Xu,et al.  Negative pressure wound therapy promotes wound healing by suppressing macrophage inflammation in diabetic ulcers. , 2021, Regenerative medicine.

[45]  Wei He,et al.  Biological drug and drug delivery-mediated immunotherapy , 2020, Acta pharmaceutica Sinica. B.

[46]  N. El-Sayed,et al.  The transition of M-CSF-derived human macrophages to a growth-promoting phenotype. , 2020, Blood advances.

[47]  A. Cowin,et al.  Systemic Delivery of Anti-Integrin αL Antibodies Reduces Early Macrophage Recruitment, Inflammation, and Scar Formation in Murine Burn Wounds. , 2020, Advances in wound care.

[48]  J. H. Lee,et al.  Tissue-remodelling M2 Macrophages Recruits Matrix Metallo-proteinase-9 for Cryotherapy-induced Fibrotic Resolution during Keloid Treatment , 2020, Acta dermato-venereologica.

[49]  C. Denton,et al.  A randomised, double-blind, placebo-controlled, 24-week, phase II, proof-of-concept study of romilkimab (SAR156597) in early diffuse cutaneous systemic sclerosis , 2020, Annals of the Rheumatic Diseases.

[50]  M. Akiyama,et al.  IL-36 receptor antagonist deficiency resulted in delayed wound healing due to excessive recruitment of immune cells , 2020, Scientific Reports.

[51]  L. Ferreira,et al.  Electric Factors in Wound Healing. , 2020, Advances in wound care.

[52]  Xiaoyuan Chen,et al.  Engineering Macrophages for Cancer Immunotherapy and Drug Delivery , 2020, Advanced materials.

[53]  Si-Yu Liu,et al.  Emerging Role of IL-10 in Hypertrophic Scars , 2020, Frontiers in Medicine.

[54]  M. Yasunaga.  Antibody therapeutics and immunoregulation in cancer and autoimmune disease. , 2020, Seminars in cancer biology.

[55]  S. Moestrup,et al.  Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases , 2020, International journal of molecular sciences.

[56]  Ryanne A. Brown,et al.  CD47 prevents the elimination of diseased fibroblasts in scleroderma , 2020, bioRxiv.

[57]  F. Ginhoux,et al.  Deciphering human macrophage development at single-cell resolution , 2020, Nature.

[58]  T. Radstake,et al.  CXCL4 triggers monocytes and macrophages to produce PDGF-BB, culminating in fibroblast activation: Implications for systemic sclerosis. , 2020, Journal of autoimmunity.

[59]  D. Green,et al.  The clearance of dead cells by efferocytosis , 2020, Nature Reviews Molecular Cell Biology.

[60]  M. Greter,et al.  Emerging roles of IL-34 in health and disease , 2020, The Journal of experimental medicine.

[61]  Guangdi Li,et al.  Clinical significance of chemokine receptor antagonists , 2020, Expert opinion on drug metabolism & toxicology.

[62]  Chunmao Han,et al.  Clinical guideline on topical growth factors for skin wounds , 2020, Burns & trauma.

[63]  S. Mitragotri,et al.  Drug delivery to macrophages: A review of targeting drugs and drug carriers to macrophages for inflammatory diseases. , 2019, Advanced drug delivery reviews.

[64]  J. Krueger,et al.  Keloid lesions show increased IL‐4/IL‐13 signaling and respond to Th2‐targeting dupilumab therapy , 2019, Journal of the European Academy of Dermatology and Venereology : JEADV.

[65]  A. Grada,et al.  Principles of Wound Dressings: A Review. , 2019, Surgical technology international.

[66]  C. Ulecia-Morón,et al.  CD163 overexpression using a macrophage-directed gene therapy approach improves wound healing in ex vivo and in vivo human skin models. , 2019, Immunobiology.

[67]  T. O’Connor,et al.  The prevalence of pressure ulcers in Europe, what does the European data tell us: a systematic review. , 2019, Journal of wound care.

[68]  J. Hamilton.  GM-CSF in inflammation , 2019, The Journal of experimental medicine.

[69]  A. Mamalis,et al.  The IL-4/IL-13 axis in skin fibrosis and scarring: mechanistic concepts and therapeutic targets , 2019, Archives of Dermatological Research.

[70]  Xiujun Fu,et al.  Blockade of lncRNA‐ASLNCS5088–enriched exosome generation in M2 macrophages by GW4869 dampens the effect of M2 macrophages on orchestrating fibroblast activation , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[71]  Houston R. Linder,et al.  A Critical Review and Perspective of Honey in Tissue Engineering and Clinical Wound Healing. , 2019, Advances in wound care.

[72]  E. Shirzaei Sani,et al.  Local Immunomodulation Using an Adhesive Hydrogel Loaded with miRNA-Laden Nanoparticles Promotes Wound Healing. , 2019, Small.

[73]  Xiaobing Fu,et al.  Advanced drug delivery systems and artificial skin grafts for skin wound healing. , 2019, Advanced drug delivery reviews.

[74]  K. Mace,et al.  Elevated Local Senescence in Diabetic Wound Healing Is Linked to Pathological Repair via CXCR2. , 2019, The Journal of investigative dermatology.

[75]  F. Ginhoux,et al.  Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches , 2019, Science.

[76]  D. Neri,et al.  Advances in antibody engineering for rheumatic diseases , 2019, Nature Reviews Rheumatology.

[77]  Brian Ruffell,et al.  Macrophages as regulators of tumour immunity and immunotherapy , 2019, Nature Reviews Immunology.

[78]  F. Tacke,et al.  Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications. , 2019, Molecular aspects of medicine.

[79]  G. Gurtner,et al.  Wound Healing: A Cellular Perspective. , 2019, Physiological reviews.

[80]  Josip Car,et al.  The humanistic and economic burden of chronic wounds: A systematic review , 2018, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[81]  J. Pollard,et al.  Targeting macrophages: therapeutic approaches in cancer , 2018, Nature Reviews Drug Discovery.

[82]  A. Sahebkar,et al.  Efferocytosis: molecular mechanisms and pathophysiological perspectives , 2018, Immunology and cell biology.

[83]  A. Ridiandries,et al.  The Role of Chemokines in Wound Healing , 2018, International journal of molecular sciences.

[84]  B. Hinz,et al.  The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication. , 2018, Matrix biology : journal of the International Society for Matrix Biology.

[85]  Paul Martin,et al.  Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression , 2018, The EMBO journal.

[86]  A. Palmer,et al.  The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Pro-wound Healing Phenotypes , 2018, Front. Physiol..

[87]  S. Shi,et al.  Local Administration of Interleukin-1 Receptor Antagonist Improves Diabetic Wound Healing , 2018, Annals of plastic surgery.

[88]  Y. Jang,et al.  Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids , 2018, International journal of molecular sciences.

[89]  Ali Khademhosseini,et al.  Drug delivery systems and materials for wound healing applications. , 2018, Advanced drug delivery reviews.

[90]  M. El-Gamal,et al.  Recent Advances of Colony-Stimulating Factor-1 Receptor (CSF-1R) Kinase and Its Inhibitors. , 2018, Journal of medicinal chemistry.

[91]  K. Khosrotehrani,et al.  Interleukin‐23 regulates interleukin‐17 expression in wounds, and its inhibition accelerates diabetic wound healing through the alteration of macrophage polarization , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[92]  D. Kaplan.  Ontogeny and function of murine epidermal Langerhans cells , 2017, Nature Immunology.

[93]  Yuejun Kang,et al.  Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis. , 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

[94]  F. Tacke.  Targeting hepatic macrophages to treat liver diseases. , 2017, Journal of hepatology.

[95]  Junna Ye,et al.  MicroRNA-155 Inhibition Promoted Wound Healing in Diabetic Rats , 2017, The international journal of lower extremity wounds.

[96]  Jenna L. Dziki,et al.  Extracellular Matrix Bioscaffolds as Immunomodulatory Biomaterials. , 2017, Tissue engineering. Part A.

[97]  Irving L. Weissman,et al.  Unifying mechanism for different fibrotic diseases , 2017, Proceedings of the National Academy of Sciences.

[98]  Dalong Zhu,et al.  Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis† , 2017, Annals of medicine.

[99]  M. Yao,et al.  Inhibition of IRF8 Negatively Regulates Macrophage Function and Impairs Cutaneous Wound Healing , 2017, Inflammation.

[100]  Joanne T. M. Tan,et al.  Broad-Spectrum Inhibition of the CC-Chemokine Class Improves Wound Healing and Wound Angiogenesis , 2017, International journal of molecular sciences.

[101]  P. Tak,et al.  Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseases , 2016, Nature Reviews Drug Discovery.

[102]  C. Jackson,et al.  Inflammation in Chronic Wounds , 2016, International journal of molecular sciences.

[103]  Burkhard Becher,et al.  GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation. , 2016, Immunity.

[104]  R. Kirsner,et al.  Adalimumab treatment leads to reduction of tissue tumor necrosis factor‐alpha correlated with venous leg ulcer improvement: a pilot study , 2016, International wound journal.

[105]  A. Iwasaki,et al.  CD301b+ Macrophages Are Essential for Effective Skin Wound Healing. , 2016, The Journal of investigative dermatology.

[106]  R. Kalluri.  The biology and function of fibroblasts in cancer , 2016, Nature Reviews Cancer.

[107]  Amitava Das,et al.  Correction of MFG-E8 Resolves Inflammation and Promotes Cutaneous Wound Healing in Diabetes , 2016, The Journal of Immunology.

[108]  C. McCaig,et al.  Electric fields are novel determinants of human macrophage functions , 2016, Journal of leukocyte biology.

[109]  M. Ståhle,et al.  Transition from inflammation to proliferation: a critical step during wound healing , 2016, Cellular and Molecular Life Sciences.

[110]  N. Bessis,et al.  Novel Immunotherapeutic Avenues for Rheumatoid Arthritis. , 2016, Trends in molecular medicine.

[111]  R. Medzhitov,et al.  Tissue biology perspective on macrophages , 2015, Nature Immunology.

[112]  W. Bloch,et al.  Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair. , 2015, Immunity.

[113]  R. Frykberg,et al.  Challenges in the Treatment of Chronic Wounds , 2015, Advances in wound care.

[114]  Ki-Hyun Kim,et al.  The Matricellular Protein CCN1 Mediates Neutrophil Efferocytosis in Cutaneous Wound Healing , 2015, Nature Communications.

[115]  C. Jackson,et al.  Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring. , 2015, Advances in wound care.

[116]  T. Koh,et al.  Contributions of cell subsets to cytokine production during normal and impaired wound healing. , 2015, Cytokine.

[117]  Paul Martin,et al.  Wound repair and regeneration: Mechanisms, signaling, and translation , 2014, Science Translational Medicine.

[118]  Hsi-Chin Wu,et al.  Tailored design of electrospun composite nanofibers with staged release of multiple angiogenic growth factors for chronic wound healing. , 2014, Acta biomaterialia.

[119]  A. Richmond,et al.  Chemokine Regulation of Neutrophil Infiltration of Skin Wounds. , 2014, Advances in wound care.

[120]  B. Malissen,et al.  The origins and functions of dendritic cells and macrophages in the skin , 2014, Nature Reviews Immunology.

[121]  Zachary D. Kurtz,et al.  Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct. , 2014, Blood.

[122]  M. Longaker,et al.  Tracking the Elusive Fibrocyte: Identification and Characterization of Collagen‐Producing Hematopoietic Lineage Cells During Murine Wound Healing , 2014, Stem cells.

[123]  L. Joosten,et al.  Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. , 2014, The New England journal of medicine.

[124]  V. Driver,et al.  A prospective, randomized clinical study evaluating the effect of transdermal continuous oxygen therapy on biological processes and foot ulcer healing in persons with diabetes mellitus. , 2013, Ostomy/wound management.

[125]  G. Kwon,et al.  pH- and ion-sensitive polymers for drug delivery , 2013, Expert opinion on drug delivery.

[126]  K. Scharffetter-Kochanek,et al.  Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing. , 2013, Advances in wound care.

[127]  Sashwati Roy,et al.  Neutrophils and Wound Repair: Positive Actions and Negative Reactions. , 2013, Advances in wound care.

[128]  H. Anders,et al.  Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair. , 2013, Biochimica et biophysica acta.

[129]  R. Bank,et al.  Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts , 2013, Cell Communication and Signaling.

[130]  K. Khosrotehrani,et al.  Reduced Il17a expression distinguishes a Ly6c(lo)MHCII(hi) macrophage population promoting wound healing. , 2013, The Journal of investigative dermatology.

[131]  F. Ginhoux,et al.  Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages , 2012, The Journal of experimental medicine.

[132]  J. Pollard,et al.  A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells , 2012, Science.

[133]  M. Sweetwyne,et al.  Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms. , 2012, Matrix biology : journal of the International Society for Matrix Biology.

[134]  S. Leibovich,et al.  Regulation of Macrophage Polarization and Wound Healing. , 2012, Advances in wound care.

[135]  Zahi A. Fayad,et al.  Perspectives and opportunities for nanomedicine in the management of atherosclerosis , 2011, Nature Reviews Drug Discovery.

[136]  S. Galli,et al.  Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils , 2011, Nature Immunology.

[137]  D. Hume,et al.  Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses. , 2011, The American journal of pathology.

[138]  P. Henson,et al.  Neutrophil clearance: when the party is over, clean-up begins. , 2011, Trends in immunology.

[139]  Frank Petersen,et al.  Molecular pathways of platelet factor 4/CXCL4 signaling. , 2011, European journal of cell biology.

[140]  Kristina M. Little,et al.  Cxc Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-derived Macrophages Address Correspondence and Reprint Requests To , 2022 .

[141]  E. Collard,et al.  Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice , 2010, PloS one.

[142]  Chunmao Han,et al.  A multicenter clinical trial of recombinant human GM‐CSF hydrogel for the treatment of deep second‐degree burns , 2009, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[143]  A. Schwarting,et al.  CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice. , 2009, The Journal of clinical investigation.

[144]  G. Schultz,et al.  Interactions between extracellular matrix and growth factors in wound healing , 2009, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[145]  P. V. van Zuijlen,et al.  Potential cellular and molecular causes of hypertrophic scar formation. , 2009, Burns : journal of the International Society for Burn Injuries.

[146]  A Bayat,et al.  The hidden cost of skin scars: quality of life after skin scarring. , 2008, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

[147]  J. Boateng,et al.  Wound healing dressings and drug delivery systems: a review. , 2008, Journal of pharmaceutical sciences.

[148]  K. Matthews,et al.  Formulation, stability and thermal analysis of lyophilised wound healing wafers containing an insoluble MMP-3 inhibitor and a non-ionic surfactant. , 2008, International journal of pharmaceutics.

[149]  L. Williams,et al.  Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome , 2008, Science.

[150]  H. Mühl,et al.  Systemic anti-TNFalpha treatment restores diabetes-impaired skin repair in ob/ob mice by inactivation of macrophages. , 2007, The Journal of investigative dermatology.

[151]  Giulio Gabbiani,et al.  The myofibroblast: one function, multiple origins. , 2007, The American journal of pathology.

[152]  T. Krieg,et al.  Inflammation in wound repair: molecular and cellular mechanisms. , 2007, The Journal of investigative dermatology.

[153]  M. Streit,et al.  Topical application of the tumour necrosis factor‐α antibody infliximab improves healing of chronic wounds , 2006, International wound journal.

[154]  Pei Wang,et al.  Glutamine granule-supplemented enteral nutrition maintains immunological function in severely burned patients. , 2006, Burns : journal of the International Society for Burn Injuries.

[155]  Kristina D. O'Shaughnessy,et al.  Chronic Wound Pathogenesis and Current Treatment Strategies: A Unifying Hypothesis , 2006, Plastic and reconstructive surgery.

[156]  E. Pamer,et al.  Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2 , 2006, Nature Immunology.

[157]  Vincent Falanga,et al.  Wound healing and its impairment in the diabetic foot , 2005, The Lancet.

[158]  S. Werner,et al.  Wound repair and regeneration , 1994, Nature.

[159]  S. Werner,et al.  Regulation of wound healing by growth factors and cytokines. , 2003, Physiological reviews.

[160]  A. Schor,et al.  Growth factors in the treatment of diabetic foot ulcers , 2003, The British journal of surgery.

[161]  bc David J. Margolisa,et al.  Venous leg ulcer: incidence and prevalence in the elderly. , 2002, Journal of the American Academy of Dermatology.

[162]  J. Pfeilschifter,et al.  Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair. , 2000, The Journal of investigative dermatology.

[163]  T. Krieg,et al.  Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds. , 2000, The Journal of investigative dermatology.

[164]  Kristi Kincaid,et al.  M-1/M-2 Macrophages and the Th1/Th2 Paradigm1 , 2000, The Journal of Immunology.

[165]  M. Ernst,et al.  The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages. , 2000, Blood.

[166]  A. Singer,et al.  Cutaneous wound healing. , 1999, The New England journal of medicine.

[167]  E. Bröcker,et al.  Chemokines IL-8, GROalpha, MCP-1, IP-10, and Mig are sequentially and differentially expressed during phase-specific infiltration of leukocyte subsets in human wound healing. , 1998, The American journal of pathology.

[168]  E. Shinar,et al.  Treatment of human ulcers by application of macrophages prepared from a blood unit , 1997, Experimental Gerontology.

[169]  F. Grinnell,et al.  Fibronectin Degradation in Chronic Wounds Depends on the Relative Levels of Elastase, α1-Proteinase Inhibitor, and α2-Macroglobulin , 1996 .

[170]  G. Kaplan,et al.  Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth, and enhanced wound healing , 1992, The Journal of experimental medicine.

[171]  OUP accepted manuscript , 2022, Burns and Trauma.

[172]  T. Litman,et al.  Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection. , 2015, The Journal of allergy and clinical immunology.

[173]  R. Kirsner.  Biological Agents for Chronic Wounds , 2010, American journal of clinical dermatology.

[174]  K. Matsushima,et al.  Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-kappaB activation and a reciprocal suppression of TGF-beta signal pathway. , 2006, Journal of immunology.

[175]  P. Vogt,et al.  [Clinical application of growth factors and cytokines in wound healing]. , 2000, Zentralblatt fur Chirurgie.

[176]  C. Di Mauro,et al.  Lyophilized collagen in the treatment of diabetic ulcers. , 1991, Drugs under experimental and clinical research.

[177]  R. van Furth,et al.  The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells. , 1972, Bulletin of the World Health Organization.