Improving oral bioavailability of water-insoluble idebenone with bioadhesive liposomes
暂无分享,去创建一个
M. Zhang | Qingmin Yang | Yaping Li | Zhiwen Zhang | Jie Li | Guanru Wang | Xinyue Zhang | Xiandi Qian
[1] A. Ungell,et al. Review of paediatric gastrointestinal physiology relevant to the absorption of orally administered medicines. , 2021, Advanced drug delivery reviews.
[2] K. Tahara,et al. Emulsion-electrospun polyvinyl alcohol nanofibers as a solid dispersion system to improve solubility and control the release of probucol, a poorly water-soluble drug , 2021, Journal of Drug Delivery Science and Technology.
[3] Tianyang Ren,et al. Bioadhesive poly(methyl vinyl ether-co-maleic anhydride)-TPGS copolymer modified PLGA/lipid hybrid nanoparticles for improving intestinal absorption of cabazitaxel. , 2021, International journal of pharmaceutics.
[4] David J Brayden,et al. Formulation strategies to improve the efficacy of intestinal permeation enhancers. , 2021, Advanced drug delivery reviews.
[5] Mo Li,et al. Effectiveness of idebenone nanorod formulations in the treatment of Alzheimer's disease. , 2021, Journal of controlled release : official journal of the Controlled Release Society.
[6] J. Leroux,et al. Physical methods for enhancing drug absorption from the gastrointestinal tract. , 2021, Advanced drug delivery reviews.
[7] A. Haeri,et al. Biopharmaceutical and pharmacokinetic aspects of nanocarrier-mediated oral delivery of poorly soluble drugs , 2021 .
[8] Xiaoyong Song,et al. Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability , 2021, Drug delivery.
[9] B. Avcı,et al. Idebenone Ameliorates Rotenone-Induced Parkinson’s Disease in Rats Through Decreasing Lipid Peroxidation , 2020, Neurochemical Research.
[10] N. Gueven,et al. Idebenone: When an antioxidant is not an antioxidant , 2020, Redox biology.
[11] A. Kabanov,et al. Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval. , 2020, Advanced drug delivery reviews.
[12] Yaping Li,et al. Phospholipid membrane-decorated deep-penetrated nanocatalase relieve tumor hypoxia to enhance chemo-photodynamic therapy , 2020, Acta pharmaceutica Sinica. B.
[13] F. Santorelli,et al. Development of Nanostructured Lipid Carriers for the Delivery of Idebenone in Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay , 2020, ACS omega.
[14] S. Hua. Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors , 2020, Frontiers in Pharmacology.
[15] Yaping Li,et al. Orally delivered legumain-activated nanovehicles improve tumor accumulation and penetration for combinational photothermal-chemotherapy. , 2020, Journal of controlled release : official journal of the Controlled Release Society.
[16] Mo Li,et al. A carbohydrate polymer is a critical variable in the formulation of drug nanocrystals: a case study of idebenone , 2019, Expert opinion on drug delivery.
[17] Wei Wu,et al. Absorption, distribution, metabolism and excretion of the biomaterials used in Nanocarrier drug delivery systems. , 2019, Advanced drug delivery reviews.
[18] C. Pouton,et al. Colloidal aspects of dispersion and digestion of self-dispersing lipid-based formulations for poorly water-soluble drugs. , 2019, Advanced drug delivery reviews.
[19] Jianping Qi,et al. Adapting liposomes for oral drug delivery , 2018, Acta pharmaceutica Sinica. B.
[20] R. Turnaturi,et al. Idebenone: Novel Strategies to Improve Its Systemic and Local Efficacy , 2018, Nanomaterials.
[21] Haotian Zhang,et al. Enhanced oral absorption and anticancer efficacy of cabazitaxel by overcoming intestinal mucus and epithelium barriers using surface polyethylene oxide (PEO) decorated positively charged polymer‐lipid hybrid nanoparticles , 2018, Journal of controlled release : official journal of the Controlled Release Society.
[22] A. Beloqui,et al. Nanostructured lipid carriers as oral delivery systems for poorly soluble drugs , 2017 .
[23] Xing-jie Liang,et al. Poly(vinyl methyl ether/maleic anhydride)-Doped PEG-PLA Nanoparticles for Oral Paclitaxel Delivery To Improve Bioadhesive Efficiency. , 2017, Molecular pharmaceutics.
[24] Xiaoming Li,et al. In vivo gastrointestinal drug-release monitoring through second near-infrared window fluorescent bioimaging with orally delivered microcarriers , 2017, Nature Communications.
[25] R. Alany. Oral dosage forms and drug delivery systems: tablets, oral films, liquid dosage forms, oral bioavailability enhancement , 2017, Pharmaceutical development and technology.
[26] B. Ruozi,et al. Innovative oral spray-dried Idebenone systems to improve patient compliance , 2016, Drug development and industrial pharmacy.
[27] K. Lyseng-Williamson. Idebenone: A Review in Leber’s Hereditary Optic Neuropathy , 2016, Drugs.
[28] J. Veuthey,et al. Strategies for formulating and delivering poorly water-soluble drugs , 2015 .
[29] R. Finkel,et al. Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial , 2015, The Lancet.
[30] Yihui Deng,et al. A review on phospholipids and their main applications in drug delivery systems , 2015 .
[31] Yaping Li,et al. Nanoassembly of probucol enables novel therapeutic efficacy in the suppression of lung metastasis of breast cancer. , 2014, Small.
[32] Haijun Yu,et al. The use of lipid-coated nanodiamond to improve bioavailability and efficacy of sorafenib in resisting metastasis of gastric cancer. , 2014, Biomaterials.
[33] M. M. Oliveira,et al. Targeted thiolation of graphene oxide and its utilization as precursor for graphene/silver nanoparticles composites , 2013 .
[34] Fang Gao,et al. Bile salts enhance the intestinal absorption of lipophilic drug loaded lipid nanocarriers: mechanism and effect in rats. , 2013, International journal of pharmaceutics.
[35] Yaping Li,et al. A self-assembled nanocarrier loading teniposide improves the oral delivery and drug concentration in tumor. , 2013, Journal of controlled release : official journal of the Controlled Release Society.
[36] Fang Gao,et al. Solid lipid nanoparticles loading candesartan cilexetil enhance oral bioavailability: in vitro characteristics and absorption mechanism in rats. , 2012, Nanomedicine : nanotechnology, biology, and medicine.
[37] Laura M Ensign,et al. Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers. , 2012, Advanced drug delivery reviews.
[38] Chunjie Zhao,et al. Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: Performance and mechanism. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[39] J. Drewe,et al. Pharmacokinetic evaluation of idebenone , 2010, Expert opinion on drug metabolism & toxicology.
[40] J M Irache,et al. Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[41] J. Drewe,et al. Pharmacokinetic properties and metabolism of idebenone , 2009, Journal of Neurology.
[42] J. Drewe,et al. Pharmacokinetics and metabolism of idebenone in healthy male subjects , 2009, European Journal of Clinical Pharmacology.
[43] K. Fischbeck,et al. Safety, tolerability, and pharmacokinetics of high-dose idebenone in patients with Friedreich ataxia. , 2007, Archives of neurology.
[44] A. Bernkop‐Schnürch,et al. Thiolated polymers: evidence for the formation of disulphide bonds with mucus glycoproteins. , 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[45] S. Chi,et al. Preparation and In Vitro Evaluation of Self-Microemulsifying Drug Delivery Systems Containing Idebenone , 2000, Drug development and industrial pharmacy.
[46] E. Mathiowitz,et al. Bioadhesive microspheres. I: A novel electrobalance-based method to study adhesive interactions between individual microspheres and intestinal mucosa , 1995 .