Contactless recording of sleep apnea and periodic leg movements by nocturnal 3-D-video and subsequent visual perceptive computing

Contactless measurements during the night by a 3-D-camera are less time-consuming in comparison to polysomnography because they do not require sophisticated wiring. However, it is not clear what might be the diagnostic benefit and accuracy of this technology. We investigated 59 persons simultaneously by polysomnography and 3-D-camera and visual perceptive computing (19 patients with restless legs syndrome (RLS), 21 patients with obstructive sleep apnea (OSA), and 19 healthy volunteers). There was a significant correlation between the apnea hypopnea index (AHI) measured by polysomnography and respiratory events measured with the 3-D-camera in OSA patients (r = 0.823; p < 0.001). The receiver operating characteristic curve yielded a sensitivity of 90% for OSA with a specificity of 71.4%. In RLS patients 72.8% of leg movements confirmed by polysomnography could be detected by 3-D-video and a significant moderate correlation was found between PLM measured by polysomnography and by the 3-D-camera (RLS: r = 0.654; p = 0.004). In total, 95.4% of the sleep epochs were correctly classified by the machine learning approach, but only 32.5% of awake epochs. Further studies should investigate, if this technique might be an alternative to home sleep testing in persons with an increased pre-test probability for OSA.

[1]  Bodo Rosenhahn,et al.  Validation of the Kinect device as a new portable imaging system for three-dimensional breast assessment. , 2014, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

[2]  Winson C.C. Lee,et al.  Evaluation of the Microsoft Kinect as a clinical assessment tool of body sway. , 2014, Gait & posture.

[3]  Marjorie Skubic,et al.  Average in-home gait speed: investigation of a new metric for mobility and fall risk assessment of elders. , 2015, Gait & posture.

[4]  J. Connor,et al.  Profile of altered brain iron acquisition in restless legs syndrome. , 2011, Brain : a journal of neurology.

[5]  Ji Eun Kim Diagnosis of REM sleep behavior disorder , 2009 .

[6]  João Paulo da Silva Cunha,et al.  A novel portable, low-cost kinect-based system for motion analysis in neurological diseases , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[7]  Joan Santamaria,et al.  Normative EMG values during REM sleep for the diagnosis of REM sleep behavior disorder. , 2012, Sleep.

[8]  J. Connor,et al.  Abnormally increased CSF 3-Ortho-methyldopa (3-OMD) in untreated restless legs syndrome (RLS) patients indicates more severe disease and possibly abnormally increased dopamine synthesis. , 2009, Sleep medicine.

[9]  Werner Poewe,et al.  A Prospective Video-Polysomnographic Analysis of Movements during Physiological Sleep in 100 Healthy Sleepers. , 2015, Sleep.

[10]  G. Plazzi,et al.  Motor pattern of periodic limb movements during sleep , 2001, Neurology.

[11]  Rainer Stiefelhagen,et al.  Action recognition in bed using BAMs for assisted living and elderly care , 2015, 2015 14th IAPR International Conference on Machine Vision Applications (MVA).

[12]  S. Quan,et al.  Rules for scoring respiratory events in sleep: update of the 2007 AASM Manual for the Scoring of Sleep and Associated Events. Deliberations of the Sleep Apnea Definitions Task Force of the American Academy of Sleep Medicine. , 2012, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[13]  Daniel J Buysse,et al.  Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. , 1999, Sleep.

[14]  Richard P Allen,et al.  Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance. , 2014, Sleep medicine.

[15]  F. Paul,et al.  Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity , 2015, Neuropsychiatric disease and treatment.

[16]  Sonia Ancoli-Israel,et al.  A novel approach using actigraphy to quantify the level of disruption of sleep by in-home polysomnography: the MrOS Sleep Study: Sleep disruption by polysomnography. , 2017, Sleep medicine.

[17]  Friedemann Paul,et al.  Using perceptive computing in multiple sclerosis - the Short Maximum Speed Walk test , 2014, Journal of NeuroEngineering and Rehabilitation.

[18]  Osman Ipsiroglu,et al.  3D detection of periodic limb movements in sleep , 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[19]  Taghi M. Khoshgoftaar,et al.  RUSBoost: A Hybrid Approach to Alleviating Class Imbalance , 2010, IEEE Transactions on Systems, Man, and Cybernetics - Part A: Systems and Humans.

[20]  R. Grunert,et al.  Development of an optical measurement system for hip implant surgery to evaluate the leg length and the hip rotation center , 2014, 2nd Middle East Conference on Biomedical Engineering.

[21]  Marjorie Skubic,et al.  Fall Detection in Homes of Older Adults Using the Microsoft Kinect , 2015, IEEE Journal of Biomedical and Health Informatics.

[22]  C. Pollak,et al.  The role of actigraphy in the study of sleep and circadian rhythms. , 2003, Sleep.

[23]  D. Bloch,et al.  Comparison of the NovaSom QSG, a new sleep apnea home-diagnostic system, and polysomnography. , 2003, Sleep Medicine.

[24]  S. Lord,et al.  Kinect-Based Five-Times-Sit-to-Stand Test for Clinical and In-Home Assessment of Fall Risk in Older People , 2015, Gerontology.

[25]  J S Wheat,et al.  Development and assessment of a Microsoft Kinect based system for imaging the breast in three dimensions. , 2014, Medical engineering & physics.

[26]  Hui Chen,et al.  Evaluation of a portable recording device (ApneaLink™) for case selection of obstructive sleep apnea , 2009, Sleep and Breathing.

[27]  W. M. Anderson,et al.  Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. Portable Monitoring Task Force of the American Academy of Sleep Medicine. , 2007, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[28]  Daniel J Buysse,et al.  Sleep–Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research , 2000 .

[29]  Martin Schätz,et al.  Extraction of breathing features using MS Kinect for sleep stage detection , 2016, Signal Image Video Process..

[30]  S. Ferré,et al.  New Insights into the Neurobiology of Restless Legs Syndrome , 2018, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[31]  Julius Verrel,et al.  Accuracy and Reliability of the Kinect Version 2 for Clinical Measurement of Motor Function , 2016, PloS one.

[32]  A. Chesson,et al.  The American Academy of Sleep Medicine (AASM) Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications , 2007 .

[33]  Friedemann Paul,et al.  Validity of visual perceptive computing for static posturography in patients with multiple sclerosis , 2016, Multiple sclerosis.

[34]  Thomas Penzel,et al.  Sleep Detection Using De-identified Depth Data , 2014, J. Mobile Multimedia.

[35]  Yi Wang,et al.  Diagnostic performance of single airflow channel recording (ApneaLink) in home diagnosis of sleep apnea , 2010, Sleep and Breathing.

[36]  C. Stam,et al.  Abnormal H-reflexes in periodic limb movement disorder; impact on understanding the pathophysiology of the disorder , 2005, Clinical Neurophysiology.

[37]  Gene Cheung,et al.  Estimating heart rate via depth video motion tracking , 2015, 2015 IEEE International Conference on Multimedia and Expo (ICME).

[38]  D. Greenblatt,et al.  The International Classification of Sleep Disorders , 1992 .

[39]  Guilherme C. S. Ruppert,et al.  Touchless gesture user interface for interactive image visualization in urological surgery , 2012, World Journal of Urology.

[40]  Richard P Allen,et al.  Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. , 2003, Sleep medicine.

[41]  Xu Xu,et al.  Accuracy of the Microsoft Kinect for measuring gait parameters during treadmill walking. , 2015, Gait & posture.

[42]  Friedemann Paul,et al.  Maximum walking speed in multiple sclerosis assessed with visual perceptive computing , 2017, PloS one.

[43]  John Cosmas,et al.  Recognition of postures and Freezing of Gait in Parkinson's disease patients using Microsoft Kinect sensor , 2015, 2015 7th International IEEE/EMBS Conference on Neural Engineering (NER).

[44]  Thomas Penzel,et al.  A comparison of radio-frequency biomotion sensors and actigraphy versus polysomnography for the assessment of sleep in normal subjects , 2015, Sleep and Breathing.