Ca2+-saturated calmodulin binds tightly to the N-terminal domain of A-type fibroblast growth factor homologous factors
暂无分享,去创建一个
[1] S. Marx,et al. Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding–deficient channels , 2020, JCI insight.
[2] A. Hudmon,et al. Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5 , 2020, bioRxiv.
[3] G. Tomaselli,et al. Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif , 2019, Nature Communications.
[4] S. Dib-Hajj,et al. Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner , 2019, Neurobiology of pain.
[5] G. Tomaselli,et al. Allosteric regulators selectively prevent Ca2+-feedback of CaV and NaV channels , 2018, eLife.
[6] R. MacKinnon,et al. Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures , 2018, Science.
[7] Christopher N. Johnson,et al. A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel. , 2018, Structure.
[8] T. Ha,et al. Voltage-gated sodium channels assemble and gate as dimers , 2017, Nature Communications.
[9] M. A. Shea,et al. Backbone resonance assignments of complexes of human voltage-dependent sodium channel NaV1.2 IQ motif peptide bound to apo calmodulin and to the C-domain fragment of apo calmodulin , 2017, Biomolecular NMR Assignments.
[10] M. A. Shea,et al. Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2. , 2017, Biophysical chemistry.
[11] D. Sacks,et al. Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α* , 2017, The Journal of Biological Chemistry.
[12] G. Pitt,et al. FGF14 is a regulator of KCNQ2/3 channels , 2016, Proceedings of the National Academy of Sciences.
[13] Manu Ben-Johny,et al. Detecting stoichiometry of macromolecular complexes in live cells using FRET , 2016, Nature Communications.
[14] X. J. Liu,et al. Spindle function in Xenopus oocytes involves possible nanodomain calcium signaling , 2016, Molecular biology of the cell.
[15] David J Weber,et al. Structure of the STRA6 receptor for retinol uptake , 2016, Science.
[16] Hailin Zhang,et al. FGF13 modulates the gating properties of the cardiac sodium channel Nav1.5 in an isoform-specific manner , 2016, Channels.
[17] G. Pitt,et al. Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action , 2016, Proceedings of the National Academy of Sciences.
[18] J. Nerbonne,et al. Proteomic analysis of native cerebellar iFGF14 complexes , 2016, Channels.
[19] M. A. Shea,et al. Opposing orientations of the anti‐psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulin , 2015, Proteins.
[20] Gert Vriend,et al. New ways to boost molecular dynamics simulations , 2015, J. Comput. Chem..
[21] Richard D. LeDuc,et al. Quantitative Proteomics Reveals Protein–Protein Interactions with Fibroblast Growth Factor 12 as a Component of the Voltage-Gated Sodium Channel 1.2 (Nav1.2) Macromolecular Complex in Mammalian Brain , 2015, Molecular & Cellular Proteomics.
[22] G. Tomaselli,et al. Regulation of the Nav1.5 cytoplasmic domain by Calmodulin , 2014, Nature Communications.
[23] Seok-Yong Lee,et al. Structural analyses of Ca2+/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation , 2014, Nature Communications.
[24] J. Nerbonne,et al. FGF14 localization and organization of the axon initial segment , 2013, Molecular and Cellular Neuroscience.
[25] Ming‐Jen Lee,et al. A Novel SCN9A Mutation Responsible for Primary Erythromelalgia and Is Resistant to the Treatment of Sodium Channel Blockers , 2013, PloS one.
[26] S. Dib-Hajj,et al. Gain-of-function Nav1.8 mutations in painful neuropathy , 2012, Proceedings of the National Academy of Sciences.
[27] H. Kurahashi,et al. Clinical spectrum of SCN2A mutations , 2012, Brain and Development.
[28] Seok-Yong Lee,et al. Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin. , 2012, Structure.
[29] F. van Petegem,et al. Crystallographic basis for calcium regulation of sodium channels , 2012, Proceedings of the National Academy of Sciences.
[30] N. Bursac,et al. Fibroblast Growth Factor Homologous Factor 13 Regulates Na+ Channels and Conduction Velocity in Murine Hearts , 2011, Circulation research.
[31] G. Pitt,et al. Identification of Novel Interaction Sites that Determine Specificity between Fibroblast Growth Factor Homologous Factors and Voltage-gated Sodium Channels* , 2011, The Journal of Biological Chemistry.
[32] M. A. Shea,et al. Structural and energetic determinants of apo calmodulin binding to the IQ motif of the Na(V)1.2 voltage-dependent sodium channel. , 2011, Structure.
[33] M. A. Shea,et al. Recognition of β–calcineurin by the domains of calmodulin: Thermodynamic and structural evidence for distinct roles , 2011, Proteins.
[34] E. Isacoff,et al. Multiple C‐terminal tail Ca2+/CaMs regulate CaV1.2 function but do not mediate channel dimerization , 2010, The EMBO journal.
[35] Egidio D'Angelo,et al. Long‐term inactivation particle for voltage‐gated sodium channels , 2010, The Journal of physiology.
[36] A. Bax,et al. SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network , 2010, Journal of biomolecular NMR.
[37] F. van Petegem,et al. A Double Tyrosine Motif in the Cardiac Sodium Channel Domain III-IV Linker Couples Calcium-dependent Calmodulin Binding to Inactivation Gating , 2009, The Journal of Biological Chemistry.
[38] K. Yamakawa,et al. De novo mutations of voltage-gated sodium channel αII gene SCN2A in intractable epilepsies , 2009, Neurology.
[39] J. Nerbonne,et al. FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels , 2009, Molecular and Cellular Neuroscience.
[40] A. Wilde,et al. Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test. , 2009, Heart rhythm.
[41] M. A. Shea,et al. Energetics of calmodulin domain interactions with the calmodulin binding domain of CaMKII , 2009, Proteins.
[42] M. Mohammadi,et al. Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels* , 2009, The Journal of Biological Chemistry.
[43] P. C. Viswanathan,et al. Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin* , 2009, Journal of Biological Chemistry.
[44] F. van Petegem,et al. Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation. , 2008, Structure.
[45] D. Douguet,et al. HELIQUEST: a web server to screen sequences with specific alpha-helical properties , 2008, Bioinform..
[46] Kengo Kinoshita,et al. Prediction of disordered regions in proteins based on the meta approach , 2008, Bioinform..
[47] M. A. Shea,et al. Interdomain cooperativity of calmodulin bound to melittin preferentially increases calcium affinity of sites I and II , 2008, Proteins.
[48] C. V. Vander Kooi,et al. Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin: high-resolution mechanistic implications for channel regulation by Ca2+. , 2008, Structure.
[49] G. Tomaselli,et al. Calmodulin Regulation of NaV1.4 Current: Role of Binding to the Carboxyl Terminus , 2008, The Journal of general physiology.
[50] M. A. Shea,et al. The neuronal voltage-dependent sodium channel type II IQ motif lowers the calcium affinity of the C-domain of calmodulin. , 2008, Biochemistry.
[51] J. Hell,et al. The NMDA receptor NR1 C1 region bound to calmodulin: structural insights into functional differences between homologous domains. , 2007, Structure.
[52] Eric S. Silver,et al. A Novel and Lethal De Novo LQT-3 Mutation in a Newborn with Distinct Molecular Pharmacology and Therapeutic Response , 2007, PloS one.
[53] Richa Agarwala,et al. COBALT: constraint-based alignment tool for multiple protein sequences , 2007, Bioinform..
[54] Anne Houdusse,et al. Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features , 2006, Proceedings of the National Academy of Sciences.
[55] D. Bers,et al. Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes. , 2006, Journal of molecular and cellular cardiology.
[56] A. Persechini,et al. Biphasic Ca2+-dependent switching in a calmodulin-IQ domain complex. , 2006, Biochemistry.
[57] J. Balser,et al. Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[58] S. Franceschetti,et al. Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[59] Filip Van Petegem,et al. Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain–Ca2+/calmodulin complex , 2005, Nature Structural &Molecular Biology.
[60] J. Nerbonne,et al. Fibroblast growth factor 14 is an intracellular modulator of voltage‐gated sodium channels , 2005, The Journal of physiology.
[61] Wayne Boucher,et al. The CCPN data model for NMR spectroscopy: Development of a software pipeline , 2005, Proteins.
[62] D. Tester,et al. Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing. , 2005, Heart rhythm.
[63] David Baker,et al. Protein structure prediction and analysis using the Robetta server , 2004, Nucleic Acids Res..
[64] K. Török,et al. Ca2+/Calmodulin-Dependent Activation and Inactivation Mechanisms of αCaMKII and Phospho-Thr286-αCaMKII† , 2004 .
[65] B. Ding,et al. Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia , 2004, Journal of Medical Genetics.
[66] M. Mohammadi,et al. Fibroblast Growth Factor (FGF) Homologous Factors Share Structural but Not Functional Homology with FGFs* , 2003, Journal of Biological Chemistry.
[67] Ron D. Appel,et al. ExPASy: the proteomics server for in-depth protein knowledge and analysis , 2003, Nucleic Acids Res..
[68] Yukitoshi Takahashi,et al. Mutations of sodium channel alpha subunit type 1 (SCN1A) in intractable childhood epilepsies with frequent generalized tonic-clonic seizures. , 2003, Brain : a journal of neurology.
[69] Sulayman D. Dib-Hajj,et al. Modulation of the Cardiac Sodium Channel Nav1.5 by Fibroblast Growth Factor Homologous Factor 1B* , 2003, The Journal of Biological Chemistry.
[70] M. A. Shea,et al. An interdomain linker increases the thermostability and decreases the calcium affinity of the calmodulin N-domain. , 2002, Biochemistry.
[71] W. Catterall,et al. Role of the C-terminal domain in inactivation of brain and cardiac sodium channels , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[72] S. Dib-Hajj,et al. Fibroblast Growth Factor Homologous Factor 1B Binds to the C Terminus of the Tetrodotoxin-resistant Sodium Channel rNav1.9a (NaN)* , 2001, The Journal of Biological Chemistry.
[73] M Montal,et al. A missense mutation of the Na+ channel αII subunit gene Nav1.2 in a patient with febrile and afebrile seizures causes channel dysfunction , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[74] M. Goldfarb,et al. Fibroblast growth factor homologous factors are intracellular signaling proteins , 2001, Current Biology.
[75] Jeffrey J. Clare,et al. Distribution of voltage‐gated sodium channel α‐subunit and β‐subunit mRNAs in human hippocampal formation, cortex, and cerebellum , 2000 .
[76] K. Nagayama,et al. Novel interaction of the voltage-dependent sodium channel (VDSC) with calmodulin: does VDSC acquire calmodulin-mediated Ca2+-sensitivity? , 2000, Biochemistry.
[77] J. Nathans,et al. Isoform Diversity among Fibroblast Growth Factor Homologous Factors Is Generated by Alternative Promoter Usage and Differential Splicing* , 2000, The Journal of Biological Chemistry.
[78] Masaya Orita,et al. A novel target recognition revealed by calmodulin in complex with Ca2+-calmodulin-dependent kinase kinase , 1999, Nature Structural Biology.
[79] A. Persechini,et al. The Relationship between the Free Concentrations of Ca2+ and Ca2+-calmodulin in Intact Cells* , 1999, The Journal of Biological Chemistry.
[80] D. T. Yue,et al. Calmodulin Is the Ca2+ Sensor for Ca2+-Dependent Inactivation of L-Type Calcium Channels , 1999, Neuron.
[81] Vann Bennett,et al. AnkyrinG Is Required for Clustering of Voltage-gated Na Channels at Axon Initial Segments and for Normal Action Potential Firing , 1998, The Journal of cell biology.
[82] J. Ovádi,et al. Simultaneous binding of drugs with different chemical structures to Ca2+-calmodulin: crystallographic and spectroscopic studies. , 1998, Biochemistry.
[83] M. A. Shea,et al. Interactions between domains of apo calmodulin alter calcium binding and stability. , 1998, Biochemistry.
[84] D. Birnbaum,et al. Murine FGF-12 and FGF-13: expression in embryonic nervous system, connective tissue and heart , 1997, Mechanisms of Development.
[85] A. Persechini,et al. Detection in Living Cells of Ca2+-dependent Changes in the Fluorescence Emission of an Indicator Composed of Two Green Fluorescent Protein Variants Linked by a Calmodulin-binding Sequence , 1997, The Journal of Biological Chemistry.
[86] J. Nathans,et al. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[87] R. Huganir,et al. Inactivation of NMDA Receptors by Direct Interaction of Calmodulin with the NR1 Subunit , 1996, Cell.
[88] S. Grzesiek,et al. NMRPipe: A multidimensional spectral processing system based on UNIX pipes , 1995, Journal of biomolecular NMR.
[89] J. Sutcliffe,et al. Calmodulin Stabilizes an Amphiphilic α-Helix within RC3/Neurogranin and GAP-43/Neuromodulin Only When Ca2+ Is Absent (*) , 1995, The Journal of Biological Chemistry.
[90] Arthur J Moss,et al. SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome , 1995, Cell.
[91] W. Cook,et al. Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex. , 1994, Biochemistry.
[92] J. Sutcliffe,et al. Mutational and biophysical studies suggest RC3/neurogranin regulates calmodulin availability. , 1994, The Journal of biological chemistry.
[93] Y. Katsube,et al. Crystal structure of basic fibroblast growth factor at 1.6 A resolution. , 1994, Journal of biochemistry.
[94] F A Quiocho,et al. Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex. , 1992, Science.
[95] H. Schulman,et al. Decoding calcium signals by multifunctional CaM kinase. , 1992, Cell calcium.
[96] D. Storm,et al. Characterization of the calmodulin binding domain of neuromodulin. Functional significance of serine 41 and phenylalanine 42. , 1991, The Journal of biological chemistry.
[97] William A. Catterall,et al. Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons , 1989, Neuron.
[98] P. Vassilev,et al. Identification of an intracellular peptide segment involved in sodium channel inactivation. , 1988, Science.
[99] C. Klee,et al. Calmodulin binding by calcineurin. Ligand-induced renaturation of protein immobilized on nitrocellulose. , 1987, The Journal of biological chemistry.
[100] W. Catterall,et al. The sodium channel from rat brain. Separation and characterization of subunits. , 1985, The Journal of biological chemistry.
[101] A. Means,et al. Bacterial expression and characterization of proteins derived from the chicken calmodulin cDNA and a calmodulin processed gene. , 1985, The Journal of biological chemistry.
[102] C. Klee,et al. Interaction of calmodulin with myosin light chain kinase and cAMP-dependent protein kinase in bovine brain. , 1981, The Journal of biological chemistry.
[103] P. Greengard,et al. Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein , 1978, Nature.
[104] W. Cheung,et al. Cyclic 3',5'-nucleotide phosphodiesterase. Demonstration of an activator. , 1970 .
[105] T. Arndt. Crystal , 2019, Springer Reference Medizin.
[106] W. Chazin,et al. NMR studies of the interaction of calmodulin with IQ motif peptides. , 2013, Methods in molecular biology.
[107] John H. Caldwell,et al. Expression and distribution of voltage-gated sodium channels in the cerebellum , 2008, The Cerebellum.
[108] D. Leahy,et al. Crystal structure of the Ca V 2 IQ domain in complex with Ca2+/ calmodulin: High-resolution mechanistic implications for channel regulation by Ca 2+ , 2008 .
[109] Cathy H. Wu,et al. UniProt: the Universal Protein knowledgebase , 2004, Nucleic Acids Res..
[110] D. Newton,et al. Regulation of the calcium signal by calmodulin. , 1986, Ciba Foundation symposium.
[111] 浅野 富子. Cyclic3',5'-nucleotide phosphodiesteraseに関する研究 , 1977 .