SUPRARENAL CARCINOMA WITH PUBERTAS PRAECOX IN A BOY THREE YEARS OF AGE

Stanley, 3 years of age, was admitted to the Long Island College Hospital for precocious development, cough and dyspnea. He was the third child of normal parents who stated that there was no history of any similar sexual precocity in either the immediate or remote family. A large infant weighing eleven pounds at birth, he developed normally until the ninth month, when it was noted that the external genitalia began to assume proportions abnormal for a child of his age. This increase in size continued until the second year, when there was an apparent cessation in growth of these parts. Pubic hair, which appeared at twelve months, rapidly increased in amount and extent, so that by the second year the suprapubic and perineal regions were involved. There was a simultaneous growth of hair on the face and back. Accompanying these physical alterations there were psychological disturbances evidenced by a change in disposition, refusal to play with his former playmates or with children of his own age, the assumptio...