Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

[1]  Mads Thomassen,et al.  Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. , 2010, Cancer research.

[2]  S. Tavtigian,et al.  Does nonsense-mediated mRNA decay explain the ovarian cancer cluster region of the BRCA2 gene? , 2006, Oncogene.

[3]  Julian Peto,et al.  Association of ESR1 gene tagging SNPs with breast cancer risk. , 2009, Human molecular genetics.

[4]  P. Deloukas,et al.  Common Regulatory Variation Impacts Gene Expression in a Cell Type–Dependent Manner , 2009, Science.

[5]  Petra C. Schwalie,et al.  A CTCF-independent role for cohesin in tissue-specific transcription. , 2010, Genome research.

[6]  A. Long,et al.  A human cell line from a pleural effusion derived from a breast carcinoma. , 1973, Journal of the National Cancer Institute.

[7]  Stephen P. Ethier,et al.  SUM-159PT cells: a novel estrogen independent human breast cancer model system , 1999, Breast Cancer Research and Treatment.

[8]  F. Couch,et al.  RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. , 2007, American journal of human genetics.

[9]  Leonardo Medico,et al.  Allelic Imbalance in BRCA1 and BRCA2 Gene Expression and Familial Ovarian Cancer , 2010, Cancer Epidemiology, Biomarkers and Prevention.

[10]  C. Molony,et al.  Genetic analysis of genome-wide variation in human gene expression , 2004, Nature.

[11]  M. Olivier.  A haplotype map of the human genome , 2003, Nature.

[12]  K. Buetow,et al.  Allelic variation in gene expression is common in the human genome. , 2003, Genome research.

[13]  D Zeng,et al.  Maximum likelihood estimation of haplotype effects and haplotype‐environment interactions in association studies , 2005, Genetic epidemiology.

[14]  Bhavinkumar B. Patel,et al.  One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. , 2008, Cancer research.

[15]  Emmanouil Collab.  A map of human genome variation from population-scale sequencing , 2011, Nature.

[16]  Karthik Devarajan,et al.  Altered Gene Expression in Morphologically Normal Epithelial Cells from Heterozygous Carriers of BRCA1 or BRCA2 Mutations , 2010, Cancer Prevention Research.

[17]  Catarina D. Campbell,et al.  A survey of allelic imbalance in F1 mice. , 2008, Genome research.

[18]  J. Hopper,et al.  Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies. , 2003, American journal of human genetics.

[19]  C. Caldas,et al.  Common germ-line polymorphism of C1QA and breast cancer survival , 2010, British Journal of Cancer.

[20]  M. Olivier.  A haplotype map of the human genome. , 2003, Nature.

[21]  Alison P. Klein,et al.  Allele-specific expression in the germline of patients with familial pancreatic cancer: An unbiased approach to cancer gene discovery , 2008, Cancer biology & therapy.

[22]  D. Pinkel,et al.  Retention of wild‐type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation , 1998, The EMBO journal.

[23]  Mark J. Dunning,et al.  BASH: a tool for managing BeadArray spatial artefacts , 2008, Bioinform..

[24]  B. Ponder,et al.  Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast , 2009, Breast Cancer Research.

[25]  J. Russo,et al.  Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. , 1990, Cancer research.

[26]  Toshihiro Tanaka.  The International HapMap Project , 2003, Nature.

[27]  C. Begg,et al.  Variation of breast cancer risk among BRCA1/2 carriers. , 2008, JAMA.

[28]  R. Young,et al.  A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells , 2007, Cell.

[29]  Edgar Wingender,et al.  The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation , 2008, Briefings Bioinform..

[30]  Christopher A. Haiman,et al.  The 8q24 cancer risk variant rs6983267 demonstrates long-range interaction with MYC in colorectal cancer , 2009, Nature Genetics.

[31]  J. S. Pedersen,et al.  A new human breast carcinoma cell line (PMC42) with stem cell characteristics. I. Morphologic characterization. , 1983, Journal of the National Cancer Institute.

[32]  Michael D. Wilson,et al.  Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding , 2010, Science.

[33]  K. Kinzler,et al.  Small changes in expression affect predisposition to tumorigenesis , 2002, Nature Genetics.

[34]  Pier Paolo Pandolfi,et al.  Subtle variations in Pten dose determine cancer susceptibility , 2010, Nature Genetics.

[35]  Weiping Ma,et al.  Embryogenesis Microarray for Profiling Gene Expression Patterns during 15,000 Unique Zebrafish Est Clusters and Their Future Use in Material Supplemental , 2022 .

[36]  T. Hudson,et al.  Mapping common regulatory variants to human haplotypes. , 2005, Human molecular genetics.

[37]  T. Rebbeck.  Inherited predisposition and breast cancer: Modifiers of BRCA1/2‐associated breast cancer risk , 2002, Environmental and molecular mutagenesis.

[38]  K. Lange,et al.  Programs for pedigree analysis: Mendel, Fisher, and dGene , 1988, Genetic epidemiology.

[39]  Mads Thomassen,et al.  Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. , 2009, Human molecular genetics.

[40]  Simon Tavaré,et al.  beadarray: R classes and methods for Illumina bead-based data , 2007, Bioinform..

[41]  P. Schmezer,et al.  Lower level of BRCA2 protein in heterozygous mutation carriers is correlated with an increase in DNA double strand breaks and an impaired DSB repair. , 2006, Cancer letters.

[42]  Alexander E. Kel,et al.  TRANSFAC® and its module TRANSCompel®: transcriptional gene regulation in eukaryotes , 2005, Nucleic Acids Res..

[43]  Dieter Niederacher,et al.  Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. , 2008, American journal of human genetics.

[44]  H. Stefánsson,et al.  Genetics of gene expression and its effect on disease , 2008, Nature.

[45]  Xiaowei Chen,et al.  Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an increased breast cancer risk. , 2008, Human molecular genetics.

[46]  Mark Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[47]  S. Liyanarachchi,et al.  Germline Allele-Specific Expression of TGFBR1 Confers an Increased Risk of Colorectal Cancer , 2008, Science.

[48]  B. Ponder,et al.  Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer , 2008, PLoS biology.

[49]  Rafael A Irizarry,et al.  Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data. , 2006, Biostatistics.