A NEW QRS DETECTION AND ECG SIGNAL EXTRACTION TECHNIQUE FOR FETAL MONITORING

["The electrocardiogram (ECG) signal, a graphical recording of the electrical potentials generated in association with heart activity, is one of many important physiological signals commonly used in clinical practice. As in adults, the well-being and status of a fetus can be assessed from a fetal ECG signal. Detecting and analyzing the fetal ECG are the primary objectives of electronic fetal monitoring. DSP based techniques have played a significant role in obtaining and processing the fetal ECG signal. There are two primary assumptions: 1) the ECG signals of interest, i.e., the maternal ECG and the fetal ECG signals, are quasi-periodic; and 2) the abdominal ECG signal is a linear combination of the maternal ECG, the fetal ECG signals, and any interference signal. Two new algorithms for ECG signal processing are introduced. A QRS detection algorithm that forms the basis for the ensuing processing of the ECG signal is discussed first. The main components of the QRS detection are two moving average filters implementing a bandpass filter and a feature enhancement filter based on an energy ratio computation. An ECG signal separation algorithm depending on QRS detection is then developed. The principle idea of the ECG signal separation algorithm is to align every cycle of the separating ECG signal through resampling, and then to apply the Fourier transforms to extract the required components. A novel fetal ECG signal extraction approach exploiting both of these fundamental signal processing algorithms is proposed for extracting the fetal ECG signal from the composite abdominal ECG signal. The maternal ECG signal is extracted first and eliminated and then the fetal ECG signal is extracted. Experimental results demonstrate the excellent flexibility of the proposed QRS detection algorithm both in terms of detection ability and detection accuracy. The fetal ECG signal extraction approach also shows promising results with a high degree of similarity between the extracted maternal ECG and fetal ECG signals and the original maternal ECG and fetal ECG signals. The morphological characteristics are also well preserved in the extracted maternal ECG and fetal ECG signals."]

[1]  D. T. Kaplan,et al.  Fetal ECG extraction with nonlinear state-space projections , 1998, IEEE Transactions on Biomedical Engineering.

[2]  Willis J. Tompkins,et al.  Automated High-Speed Analysis of Holter Tapes with Microcomputers , 1983, IEEE Transactions on Biomedical Engineering.

[3]  P. Strobach,et al.  Event-synchronous cancellation of the heart interference in biomedical signals , 1994, IEEE Transactions on Biomedical Engineering.

[4]  Willis J. Tompkins,et al.  Quantitative Investigation of QRS Detection Rules Using the MIT/BIH Arrhythmia Database , 1986, IEEE Transactions on Biomedical Engineering.

[5]  Kenneth E. Barner,et al.  Partition-based weighted sum filters for image restoration , 1999, IEEE Trans. Image Process..

[6]  Jonathon A. Chambers,et al.  Fetal electrocardiogram extraction by sequential source separation in the wavelet domain , 2005, IEEE Transactions on Biomedical Engineering.

[7]  E.J. Delp,et al.  Impulsive noise suppression and background normalization of electrocardiogram signals using morphological operators , 1989, IEEE Transactions on Biomedical Engineering.

[8]  Asoke K. Nandi,et al.  Noninvasive fetal electrocardiogram extraction: blind separation versus adaptive noise cancellation , 2001, IEEE Transactions on Biomedical Engineering.

[9]  B. Brambati,et al.  THE INTRAVENTRICULAR CONDUCTION TIME OF FETAL HEART IN UNCOMPLICATED PREGNANCIES , 1980, British journal of obstetrics and gynaecology.

[10]  C. Li,et al.  Detection of ECG characteristic points using wavelet transforms. , 1995, IEEE transactions on bio-medical engineering.

[11]  W.J. Tompkins,et al.  Neural-network-based adaptive matched filtering for QRS detection , 1992, IEEE Transactions on Biomedical Engineering.

[12]  Shahriar Negahdaripour,et al.  A new method for the extraction of fetal ECG from the composite abdominal signal , 2000, IEEE Transactions on Biomedical Engineering.

[13]  G. Saha,et al.  Fetal ECG extraction from single-channel maternal ECG using singular value decomposition , 1997, IEEE Transactions on Biomedical Engineering.

[14]  P.E. Trahanias,et al.  An approach to QRS complex detection using mathematical morphology , 1993, IEEE Transactions on Biomedical Engineering.

[15]  M. Lewis Review of electromagnetic source investigations of the fetal heart. , 2003, Medical engineering & physics.

[16]  H. K. Verma,et al.  ANN-based QRS-complex analysis of ECG. , 1998, Journal of medical engineering & technology.

[17]  Kenneth E. Barner,et al.  An interference cancellation algorithm for noninvasive extraction of transabdominal fetal electroencephalogram (TaFEEG) , 2004, IEEE Transactions on Biomedical Engineering.

[18]  B. Widrow,et al.  Adaptive noise cancelling: Principles and applications , 1975 .

[19]  A Kandori,et al.  Prenatal diagnosis of long QT syndrome using fetal magnetocardiography , 1999, Prenatal diagnosis.

[20]  G. Boudreaux-Bartels,et al.  Wavelet transform-based QRS complex detector , 1999, IEEE Transactions on Biomedical Engineering.

[21]  Stéphane Mallat,et al.  Singularity detection and processing with wavelets , 1992, IEEE Trans. Inf. Theory.

[22]  Joos Vandewalle,et al.  Fetal electrocardiogram extraction by blind source subspace separation , 2000, IEEE Transactions on Biomedical Engineering.

[23]  Alan V. Oppenheim,et al.  Discrete-Time Signal Pro-cessing , 1989 .

[24]  Masahiko Okada,et al.  A Digital Filter for the ORS Complex Detection , 1979, IEEE Transactions on Biomedical Engineering.

[25]  S. Suppappola,et al.  Nonlinear transforms of ECG signals for digital QRS detection: a quantitative analysis , 1994, IEEE Transactions on Biomedical Engineering.

[26]  M. Okada A digital filter for the QRS complex detection. , 1979, IEEE transactions on bio-medical engineering.

[27]  H. T. Nagle,et al.  A comparison of the noise sensitivity of nine QRS detection algorithms , 1990, IEEE Transactions on Biomedical Engineering.